| Sunrise
Course: |
| MRI and MRS of the Mouse Brain: Techniques and Applications |
| Organizers:
Jeffry R. Alger, Ph.D. and Afonso C. Silva, Ph.D. |
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| Skill Level: Intermediate |
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| Tuesday, 21 April 2009 -
Friday, 24 April 2009 |
| 07:00 - 08:00 |
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| OVERVIEW |
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This four hour course will
teach how to perform the following types of mouse brain
MRI studies: anatomical (T1- and T2-weighted) imaging,
diffusion tensor imaging, functional imaging and
magnetic resonance spectroscopy. Each technical
introduction will be followed by a survey of significant
biomedical findings that have been obtained with the
particular type of MRI. |
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| EDUCATIONAL OBJECTIVES
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Upon completion of this
case based session, participants should be able to:
- Identify hardware/software configurations that
are needed to perform anatomical imaging, diffusion
tensor imaging, functional imaging and magnetic
resonance spectroscopy in the mouse brain;
- Recognize the constraints associated with the
small size of the mouse body and brain and how to
achieve stable physiology of the animals during the
MRI/MRS experiments;
- Define how to perform anatomical imaging,
diffusion tensor imaging, functional imaging and
magnetic resonance spectroscopy in the mouse brain;
- Describe the anatomical or physiological
properties that can be measured with MRI in mouse
brain; and
- Identify significant biomedical findings that
have been obtained through mouse brain neuroimaging
using anatomical imaging, diffusion tensor imaging,
functional imaging and magnetic resonance
spectroscopy.
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| Tuesday, 21 April 2009 |
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Anatomical MRI of
the Mouse Brain |
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| 07:00 |
Techniques for Anatomic Brain Imaging of Mouse Brain
|
Robia G. Pautler, Ph.D. |
| 07:30 |
Evaluation of Mouse
Brain Development with MRI |
Daniel
H. Turnbull, Ph.D. |
| 08:00 |
Adjournment |
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| Wednesday, 22 April
2009 |
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Diffusion Tensor Imaging |
| 07:00 |
Techniques for
Diffusion Tensor Imaging in Mouse Brain |
Jiangyang Zhang, Ph.D. |
| 07:30 |
Diffusion Tensor
Imaging of Multiple Sclerosis Models |
Sheng-Kwei Victor Song, Ph.D. |
| 08:00 |
Adjournment |
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Thursday, 23 April 2009 |
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Functional Brain Imaging |
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| 07:00 |
How to
Image CBF in the Mouse Brain |
Frank Kober, Ph.D. |
| 07:30 |
Functional Magnetic Resonance Imaging of the Mouse
Olfactory System |
Kai-Hsiang Chuang, Ph.D.
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| 08:00 |
Adjournment |
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| Friday, 24 April
2009 |
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Magnetic
Resonance Spectroscopy |
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| 07:00 |
MRS in Mice Models of Neurodegenerative Diseases |
Ivan
Tkac, Ph.D. |
| 07:30 |
Measurements of Glutamate/GABA/Glutamine Cycling in
the Mouse Brain |
Kevin L. Behar, Ph.D. |
| 08:00 |
Adjournment |
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