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Keywords: Cardiovascular: Vascular

Intracranial aneurysm is a major cause of hemorrhagic stroke. Traditional imaging methods only evaluate the lumen geometry but not the underlying pathology of the aneurysm wall. Contrast enhanced vessel wall MRI can identify the neovasculature – a marker of inflammation. Dynamic contrast enhanced MRI can identify wall permeability. 4D flow MRI can identify hemodynamic factors that contribute to aneurysm progression and rupture. These MRI-based novel imaging markers have been investigated in many cross-sectional and longitudinal clinical studies and showed promises. This talk will cover both the recent technical development of intracranial aneurysm imaging and also its applications.  

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Keywords: Neuro: Cerebrovascular, Cardiovascular: Vascular

Cerebrovascular disease, a major cause of morbidity and mortality worldwide, can arise from diverse intracranial vessel wall pathologies such as atherosclerosis, dissection, and vasculitis. Methods traditionally used for the diagnosis of the disease are based on lumenography imaging, which is limited to the detection of luminal abnormalities and thus inadequate for differentiating various wall pathologies. Recently, there is a growing interest in intracranial MR vessel wall imaging due to its capacity to directly assess various vessel wall pathologies and to potentially unravel etiology. This talk will provide an overview of technical advances and clinical applications of this new technology.