Kousaku Saotome¹, Koji Matsumoto², Yoshiaki Kato³, Yoshihiro Ozaki⁴, Motohiro Nagai³, Tomoyuki Hasegawa⁵, Hiroki Tsuchiya⁶, and Tensho Yamao^1
1Department of Radiological Sciences, School of Health Sciences, Fukushima Medical University, Fukushima, Japan, ²Chiba University Hospital, Chiba, Japan, ³Kameda General Hospital, Kamogawa-shi, Japan, ⁴Meiwa Hospital, Nishinomiya-shi, Japan, ⁵Hitachinaka General Hospital, Hitachinaka-shi, Japan, ⁶QST Hospital, Anagawa-shi, Japan

Motivation: Finding ways to use the PROPELLER sequence as an even more the robustness method to motion.

Goal(s): This study investigates whether repositioning the head after pausing during PROPELLER imaging, enhances image quality.

Approach: This study investigated whether image quality improved with repositioning the head after a pause during PROPELLER method with a brain phantom and driver system.

Results: We found that image quality improved at all rotational angles and that pausing multiple times was effective depending on the frequency of motion.

Impact: Incorporating a pause function into the PROPELLER method is expected to be clinically applicable as a practical means to further improve the robustness of the PROPELLER method to motion.

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omaima said¹, Sabrina Doblas¹, Gwenaël Pagé¹, Dominique Valla^1,2, Valérie Paradis^1,2, Bernard Van Beers^1,2, and Philippe Garteiser^1
1INSERM, Paris, France, ²Beaujon University Hospital, Paris, France

Motivation: In nonalcoholic fatty liver disease (NAFLD), hepatic fibrosis is strongly associated with patient survival. Diffusion MRI has been proposed to assess liver fibrosis, but this evaluation is hampered in hepatic steatosis. 

Goal(s): Our goal was to evaluate the diagnostic performance of non-Gaussian diffusion MRI in assessing liver fibrosis in 250 patients with NAFLD. 

Approach: We developed a method to calculate the non-Gaussian diffusion coefficient, based on non-linear regression and fat correction. 

Results: With this corrected diffusion method, NAFLD patients with liver fibrosis could be differentiated from patients without it.

Impact: With this corrected diffusion method, NAFLD patients with liver fibrosis could be differentiated from patients without it.

Guido Rene van Haren¹, Teresa Goncalves Ferreira², Jan Willem Beenakker³, and Myriam Jaarsma-Coes^1
1Radiology, LUMC Leiden, Leiden, Netherlands, ²Radiology, LUMC, Leiden, Netherlands, ³Radiology and ophtalmology, LUMC, Leiden, Netherlands

Keywords:

Motivation: Proton therapy is a relatively new option for treatment of uveal melanomas. For adequate treatment, accurate measurement of tumour dimensions and tumour-marker distance is essential. The dedicated MRI protocol for uveal melanoma patients developed in our institution could be helpful.

Goal(s): In this study, we compared MRI-based measurements with conventional ophthalmic measurements.

Approach: Retrospectively, MRI based measurements of  tumour dimensions and marker-tumour distances in 23  patients were compared with conventional ophthalmic measurements and evaluated.

Results: MRI allowed for the three-dimensional assessment of the tumour. In specific patients, it provided a more reliable measurement of tumour dimensions and marker-tumour distances.

Impact:  Dedicated ocular MRI proved to be  a reliable tool for measurements required in the planning of proton therapy in patients with uveal melanoma.