Novel and Smart Contrast Agents

16:30         166.      In Vivo Tracking of Gene Delivery Modules to Central Nervous System Using a Novel Susceptibility MRI Contrast Agent - not available

Young Kim¹, Christina Liu¹, Shuning Huang¹, Bruce Rosen¹, Philip Liu¹

¹MGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA

16:42         167.      Novel “Smart” ¹H MRI Contrast Agents for Assessing LacZ Gene Expression

Jian-Xin Yu¹, Li Liu¹, Vikram D. Kodibagkar¹, Weina Cui¹, Robert D. Gerard¹, Ralph P. Mason¹

¹University of Texas Southwestern Medical Center, Dallas, Texas, USA

16:54         168.      ¹⁹F CSI of Gene-Reporter Molecule OFPNPG - not available

Vikram D. Kodibagkar¹, Jianxin Yu¹, Li Liu¹, Hoby P. Hetherington², Stephen L. Brown³, Robert D. Gerard¹,

Ralph P. Mason¹

¹University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA; ²Albert Einstein College of Medicine, Bronx, New York, USA; ³Henry Ford Health System, Detroit, Michigan, USA

17:06         169.      Persistent Anti-Angiogenic Effectiveness in Early Atherosclerosis Following a Single ανβ3-Targeted Administration of Fumagillin Paramagnetic Nanoparticles at 1.5 T - not available

Patrick M. Winter¹, Anne M. Morawski, Shelton D. Caruthers ², Thomas D. Harris³, Grace Hu, Ralph W. Fuhrhop, Huiying Zhang, John S. Allen, Elizabeth K. Lacy, Todd A. Williams, Samuel A. Wickline, Gregory M. Lanza

¹Washington University, St. Louis, Missouri, USA; ²Philips Medical Systems, Cleveland, Ohio, USA; ³Bristol-Myers Squibb Medical Imaging, Billerica, Massachusetts, USA

17:18         170.      Molecular MR Imagining of the Estrogen Receptor Using a Novel Contrast Agent - not available

Erez Eyal¹, David Milstein¹, Hadassa Degani¹, Sarbani Mukhopadhyay¹, Dalia Seger¹, Raanan Margalit¹,

Ronit Hirsch¹, Yehoshua Ben-David¹, Edna Furman-Haran¹

¹Weizmann Institute of Science, Rehovot, Israel

17:30         171.      Development of ¹³C and ¹⁵N Contrast Agents Employing PASADENA - not available

Pratip Bhattacharya^1,2, Daniel P. Weitekamp¹, Kent C. Harris², Alexander Peter Lin³, Brian D. Ross, ^1,2

¹California Institute of Technology, Pasadena, California, USA; ²Huntington Medical Research Institutes, Pasadena, California, USA; ³Rudi Schulte Research Institute, Pasadena, California, USA

17:42         172.      Quantifying Exchange Rates in CEST Agents Using Saturation Time and Saturation Power Dependencies of the Magnetization Transfer Effect (QUEST and QUESP) - not available

Michael T. McMahon^1,2, Assaf A. Gilad¹, Jinyuan Zhou^1,2, Jeff W.M. Bulte¹, Peter C.M. van Zijl^1,2

¹Johns Hopkins School of Medicine, Baltimore, Maryland, USA; ²Kennedy Krieger Institute, Baltimore, Maryland, USA

17:54         173.      Characterization of HE-24.8: A New Contrast Agent for Experimental Magnetic Resonance Angiography

Fabian Maximilian Kiessling¹, Melanie Heilmann¹, Peter Peschke¹, Karel Ulbrich², Vladimir Subr², Twan Lamers¹, Lothar Schad, Wolfhard Semmler¹

¹German Cancer Research Center, Heidelberg, Germany; ²Institute of Macromolecular Chemistry, Prague, Czech Republic

18:06         174.      Characterization of Relaxational Properties of New Bis-Hydrazide-Gd-DTPA-Complexes as Contrast Agents for Molecular MRI

Timo Dansauer¹, Ekkehard Kuestermann¹, Dorit Kemken¹, Dieter Leibfritz¹

¹University of Bremen, Bremen, Germany

18:18         175.      Comparision of Poly(L-Glutamic Acid)Gd (III)-DOTA Conjugate with Degradable and Non-Degradable Spacers for Magnetic Resonance Imaging

T. Ke¹, Y. Feng¹, F. Ye¹, J. Guo¹, D. L. Parker¹, Z-R. Lu¹

¹University of Utah, Salt Lake City, Utah, USA