MR Spectroscopy of Cerebral Energetics and Neurotransmission

Room A 101-102      16:00 - 18:00                                     Chairs: Rolf Gruetter and Graeme F. Mason

16:00      542.    Quantitative Modelling of H3 Hydrogen Turnover in (2-13C) Glutamate and (2-13C) Glutamine During (1-13C) Glucose Metabolism in the Adult Rat Brain  - not available

Alejandra Sierra1, Luis Lopes da Fonseca2, Tiago Brandao Rodrigues1, Marina Benito1, Paloma Ballesteros3, Sebastian Cerdan1

1IIB-CSIC, Madrid, Spain; 2Instituto de Tecnologia Quimica e Biologica, Lisbon, Portugal; 3UNED, Madrid, Spain
 

16:12      543.    Suppression of Glial Glutamine Release to the ECF Studied in Vivo by N-15 NMR and Microdialysis/HSQC

Keiko Kanamori1, Brian D. Ross1

1Huntington Medical Research Institutes, Pasadena, California, USA
 

16:24      544.    Glucose Transport Kinetics Upregulates in Chronic Hypoglycemic Rats: An in Vivo 13C MRS Approach  - not available

Hongxia Lei1, Rolf Gruetter1

1University of Minnesota, Minneapolis, Minnesota, USA
 

16:36      545.    MR Determination of Neurochemical Profile and TCA Cycle Flux Reveals Concomitant Alterations of GABA/Glutamine Metabolism and Oxidative Pathway in a Primate Model of Huntington's Disease

Fawzi Boumezbeur1, Laurent Besret2, Julien Valette1, Martine Guillermier2, Francoise Vaufrey1, Philippe Hantraye1, Gilles Bloch1, Vincent Lebon1

1CEA-SHFJ, Orsay, France; 2URA CEA-CNRS 2210, Orsay, France
 

16:48      546.    In Vivo Detection of Altered GABA Levels Following Acute Administration of Antidepressant/Antipanic Drug Phenelzine
 - not available

Jehoon Yang1, Jun Shen1

1National Institute of Mental Health, Bethesda, Maryland, USA
 

17:00      547.    Localized 1H MR Spectroscopy in the alert Monkey at 7 Tesla  - not available

Josef Pfeuffer1, Christoph Juchem1, Hellmut Merkle2, Nikos K. Logothetis1

1Max Planck Institute for biological Cybernetics, Tuebingen, D, Germany; 2National Institutes of Health, Bethesda, Maryland, USA
 

17:12      548.    Metabolic Alterations in Rat Somatosensory Cortex During Forepaw Stimulation Measured by 1H-MR Spectroscopy at 11.7 T

Su Xu1, Jehoon Yang1, Charles Q. Li1, Wenjun Zhu1, Jun Shen1

1National Institute of Mental Health, Bethesda, Maryland, USA
 

17:24      549.    Regional Difference of GABA Concentration in the Human Brain Measured by MEGA-PRESS with LCModel Fitting on Clinical 3T Apparatus

Masafumi Harada1, Hitoshi Kubo1, Minoru Sakama1, Masako Minato1, Hiromu Nishitani1, Tsuyoshi Matsuda2

1University of Tokushima, Tokushima City, Tokushima Prefecture, Japan; 2GE-Yokogawa Medical Ltd., Tokyo, Japan
 

17:36      550.    A Shim Mapping Method for Spectroscopic Imaging of the Mouse Brain at 9.4T

Naoyuki Miyasaka1, Kan Takahashi1, Jullie W. Pan1, Hoby P. Hetherington1

1Albert Einstein College of Medicine, Bronx, New  York, USA
 

17:48      551.    MR Spectroscopic Measurement of Inhomogeneous Temperature Distribution in the Rat Brain

Mingming Zhu1,2, Joseph J. H. Ackerman1,2, Dmitriy A. Yablonskiy, 1,2

1Washington University, Saint Louis, Missouri, USA; 2Washington University School of Medicine, Saint Louis, Missouri, USA