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Molecular Imaging in
Atherosclerosis
Room 6E
16:30 - 18:30
Chairs: Zahi A. Fayad and Patrick M. Winter
Time |
Prog # |
|
16:30 |
554. |
Multimodality
Validation and Mechanistic Explanation of Functional Restoration of
Murine Model of Myocardial Infarction
by Mouse Embryonic
Stem Cells
Phillip C. Yang1,
Shoko Ikeda1, Brett Fenster1, Stephen Hendry1,
Sally Zhang1, Micha Drukker1, Irv Weissman1,
Philip Tsao1,
Robert C. Robbins1
1Stanford
University, Stanford, California, USA |
16:42 |
555. |
MRI Tracking of the Regional
Persistence of Feridex-Labeled Mesenchymal Stem Cells in a Canine Myocardial
Infarction
Model
Ana Victoria Soto1,
Wesley D. Gilson1, Dorota Kedziorek1, Adit Tal1,
Danielle Crawford1, Parag Karmarker1,
Randell G. Young2,
Mark F. Pittenger3, Jeff W. M. Bulte1, Dara L. Kraitchman1
1Johns
Hopkins University, Baltimore, Maryland, USA; 2Osiris Therapeutics,
Inc, Baltimore, Maryland, USA; 3Johns Hopkins University School of
Medicine, Baltimore, Maryland, USA |
16:54 |
556. |
Tracking of Intra-Coronary
Delivered Mesenchymal Stem Cells Using MRI in a Porcine Model of Myocardial
Infarction
John J. Graham1,
Warren D. Foltz2, Yeusong Yang1, Jay S. Detsky3,
Graham A. Wright1, 3, Alexander J. Dick1
1Sunnybrook
and Women's College Health Sciences Centre, Toronto, ON, Canada; 2St
Michael's Hospital, Toronto, ON, Canada; 3University of Toronto,
Toronto, ON, Canada |
17:06 |
557. |
Relationship Between
Macrophage Content and MRI Signal Intensity of Atherosclerosis Using
Gadolinium-Containing
Immunomicelles Targeted to
Macrophage Scavenger Receptor
Smbat
Amirbekian1, Vardan Amirbekian2, Juan Gilberto S.
Aguinaldo, Juan Carlos Frias, Venkatesh Mani,
Karen C.
Briley-Saebo, Esad Vucic, Marc Sirol, Zahi Adel Fayad
1Emory
University School of Medicine - Mount Sinai School of Medicine, New York, USA;
2Johns Hopkins University School of Medicine - Mount Sinai School of
Medicine, New York, USA |
17:18 |
558. |
Method for Specific Detection
of Plaque Angiogenesis in the Cholesterol-Fed Apolipoprotein-E Deficient Mouse
with MR
Fluorine Spectroscopy of
Integrin-Targeted Perfluorocarbon Nanoparticles at 11.7T
Emily A. Waters1,
2, John Stacy Allen2, Huiying Zhang2, Gregory M.
Lanza2, Samuel A. Wickline, 12, Junjie Chen2
1Washington
University in St. Louis, St. Louis, Missouri, USA; 2Washington
University School of Medicine, St. Louis, Missouri, USA |
17:30 |
559. |
Imaging of Atherosclerosis
In Vivo Using a Magnetic Resonance Contrast Probe Molecularly Targeted to
Matrix
Metalloproteinases (MMPs)
Smbat Amirbekian1,
Juan Gilberto S. Aguinaldo, Vardan Amirbekian2, Marc Sirol, Fabien
Hyafil, Esad Vucic, Venkatesh Mani, Eric
Lancelot3, Claire
Corot3, Zahi Adel
Fayad
1Emory
University School of Medicine - Mount Sinai School of Medicine, New York, USA;
2Johns Hopkins University School of Medicine - Mount Sinai School of
Medicine, New York, USA; 3Guerbet, Paris, France |
17:42 |
560. |
Visualizing the Uptake of
Combidex® (Ferumoxtran-10) in a Rat Model of AAA Using Positive and
Negative Contrast
Methods
Joan M. Greve1,
Eiketsu Sho2, Maureen Tedesco1, Masahiro Terashima1,
Michael V. McConnell1, Ronald L. Dalman1, Maj Hedehus3,
Charles H. Cunningham1,
Steven M. Conolly4, Charles A. Taylor1
1Stanford
University, Stanford, California, USA; 2KAI Pharmaceuticals, Inc.,
South San Francisco, California, USA; 3Varian, Inc., Palo Alto,
California, USA; 4University of California Berkeley, Berkeley,
California, USA |
17:54 |
561. |
In Vivo MR Imaging of
Bone Marrow Cell Trafficking to Atherosclerotic Plaques
Bensheng Qiu1, Fabao
Gao1, Piotr Walczak1, Jiangyang Zhang1, Sourav
Kar1, Jeff WM Bulte1, Xiaoming Yang1
1Johns
Hopkins Univ School of Medicine, Baltimore, Maryland, USA |
18:06 |
562. |
Molecular Imaging of
Angiogenic Therapy in Peripheral Vascular Disease with Alphanubeta3-Targeted
Nanoparticles
Patrick M. Winter1,
Shelton D. Caruthers1, 2, John S. Allen1, Todd
A. Williams1, Thomas D. Harris3,
Samuel A. Wickline1,
Gregory M. Lanza1
1Washington
University, St. Louis, Missouri, USA; 2Philips Medical Systems,
Cleveland, Ohio, USA; 3Bristol-Myers Squibb Medical Imaging,
Billerica, Massachusetts, USA |
18:18 |
563. |
Positive Contrast MR Imaging
of In Vivo Atherosclerosis in a Rabbit Model Using Ultrasmall Iron Oxide
Particles
Karen C.
Briley-Saebo1, Venkatesh Mani1, Fabien Hyafil1,
Zahi A. Fayad1
1Mount
Sinai School of Medicine, New York, New York, USA |
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