Myocardial Function and Strain Analysis

                  1634.    Single Breath-Hold Whole-Heart 3D CINE Imaging Using Kt-BLAST and Kt-SENSE

Marcus Katoh¹, Elmar Spuentrup¹, Arno Buecker¹, Marc Kouwenhoven², Jürgen Bunke², Rolf W. Guenther¹,

Thoralf Niendorf¹, Thoralf Niendorf¹

¹RWTH Aachen University Hospital, Aachen, Germany; ²Philips Medical Systems, Best, Netherlands

                  1635.    Fast 3D Cine Steady-State Free Precession Imaging with Sensitivity Encoding for Assessment of
                                Left Ventricular Function in a Single Breath-Hold

Neil B. Mascarenhas¹, Raja Muthupillai², ³, Benjamin Cheong², Mercedes Pereyra², Scott D. Flamm, ¹²

¹Baylor College of Medicine, Houston, Texas, USA; ²St. Luke's Episcopal Hospital/Texas Heart Institute, Houston, Texas, USA; ³Philips Medical Systems, Cleveland, Ohio, USA

                  1636.    Single Breath-Hold 3D Cine Imaging of the Heart: A Non-Angulated Isotropic Acquisition Using
                                SENSE on a 32 Channel System

Vivek Muthurangu¹, Nicholas MI Noble², Redha Boubertakh¹, Richard Winkelmann³, Peter Börnert⁴, Derek L. G. Hill², Reza S. Razavi¹

¹King's College London, London, UK; ²University College London, London, UK; ³University of Karlsruhe, Karlsruhe, Germany; ⁴Philips Research Laboratories, Hamburg, Germany

                  1637.    Minimized Off-Resonance Effects with Centric Radial SSFP for Imaging Cardiac Function

Matthew D. Robson¹, Stefan Neubauer¹

¹Oxford University, Oxford, Oxfordshire, UK

                  1638.    A Reproducibility Comparison of Quantitative Left Ventricular Assessments in Healthy Volunteers
                                Using Different MRI Scanners - Implications for Multicentre Cardiac MRI Studies

Stephen J. Gandy¹, Shelley A. Waugh¹, R Stephen Nicholas¹, Helen Simpson², Wendy Milne¹, Tracy Rylott³,

J Graeme Houston¹

¹NHS Tayside, Ninewells Hospital, Dundee, Angus, UK; ²School of Medicine, University of Dundee, Dundee, Angus, UK; ³NHS Tayside, Perth Royal Infirmary, Perth, Perthshire, UK

                  1639.    Range of Biventricular Dimensions and Function Evaluated by Steady State Free Precession
                                Cine Magnetic Resonance in Patients with Repaired Tetralogy of Fallot

Margaret Mary Samyn¹, Andrew J. Powell¹, Ruchira Garg¹, Laureen Sena¹, Tal Geva¹

¹Children's Hospital Boston, Boston, Massachusetts, USA

                  1640.    Longitudinal, Radial, and Circumferential Myocardial Velocities in Patients with Ventricular Dyssynchrony

Jana Delfino¹, Mobit Bhasin, Angel Leon, Robert Eisner, John Oshinski¹

¹Georgia Institute of Technology/ Emory University, Atlanta, Georgia, USA

                  1641.    Pre- And Postcontrast Three-Dimensional Cardiac Cine MRI Using SENSE and K-T BLAST

Yasuo Amano¹, Tatsuo Kumazaki¹, Yuriko Suzuki²

¹Nippon Medical School, Tokyo, Japan; ²Philips Medical System, Tokyo, Japan

                  1642.    Acquisition of Black-Blood Cine Cardiac Images in a Single Heartbeat at 3.0T

Ahmed S. Fahmy¹, Li Pan¹, Nael F. Osman¹

¹Johns Hopkins University, Baltimore, Maryland, USA

                  1643.    A Double Navigator Approach to Double Inversion Recovery Fast Spin Echo Imaging in Black Blood
                                Cardiac MRI

Pascal Spincemaille¹, Thanh D. Nguyen¹, Martin Prince¹, Yi Wang¹

¹Weill Medical College of Cornell University, New York, USA

                  1644.    MR Compatible Heart Phantom for Medical Research

Holger Timinger¹, Sascha Krueger¹, Joern Borgert¹

¹Philips Research, Hamburg, Germany

                  1645.    An MRI-Based Beating Heart Model

Qing Wei¹, Stuart Crozier¹, Ben Appleton¹, Ling Xia², Feng Liu¹, Stephen Wilson¹, Wendy Strugnell³,

Richard Slaughter³, Robyn Riley³

¹The University of Queensland, Brisbane, Queensland, Australia; ²ZheJiang University, HangZhou, ZheJiang, People’s Republic of China; ³The Prince Charles Hospital, Brisbane, Queensland, Australia

                  1646.    Balanced 2D Radial Acquisition SSFP of the Mouse Heart at 7 Tesla

Elizabeth Kathleen Bucholz¹, G. Allan Johnson¹

¹Duke University, Durham, North Carolina, USA

                  1647.    Direct Measurement of Intra Ventricular and Atrial Pressures Concurrent with MR Image Acquisiton

S. David Smith¹, ², Helene Benveniste², ³, G. Ron Morris⁴, Svante Hojer⁵, Igor Izrailtyan³, Mei Yu², Congwu Du², Zhongchi Luo⁶, Yu Ma², Hai-Dee Lee², Igor Feinstein⁷

¹INNOVISION Diagnostic Imaging Corp., Bellport, New York, USA; ²Brookhaven National Laboratories, Upton, New York, USA; ³Stony Brook Hospital, Stony Brook, New York, USA; ⁴SA Instruments, Inc., Stony Brook, New York, USA; ⁵Samba Instruments, Inc., Gotenburg, Sweden; ⁶Stony Brook University, Stony Brook, New York, USA; ⁷New York University, New York, New York, USA

                  1648.    Slice Refocusing Signal for Retrospective Reconstruction of CINE Cardiac MR Images

Arno Nauerth¹, Edwin Heijman², Claudia Diekmann¹

¹Bruker BioSpin MRI GmbH, Ettlingen, Germany; ²Eindhoven University of Technology, Eindhoven, Netherlands

                  1649.    Optimal Combination of Phase Cycling and Gradient Spoiling in DENSE Displacement Mapping

Eric Bennett¹, Bruce Spottiswoode², Christine H. Lorenz², Han Wen¹

¹National Institutes of Health, Bethesda, Maryland, USA; ²Siemens, Bethesda, Maryland, USA

                  1650.    Combining 2D DENSE and SENC to Calculate the 3D Strain Tensor

Aaron Timothy Hess¹, Xiaodong Zhong², Bruce Shawn Spottiswoode¹, Frederick H. Epstein², Ernesta M. Meintjes¹

¹University of Cape Town, Cape Town, Western Cape, South Africa; ²University of Virginia, Charlottesville, Virginia, USA

                  1651.    DENSE and HARP: Two Views on the Same Technique of Phase-Based Strain Imaging

Joost Kuijer¹, Mark B. Hofman¹, Jaco J. Zwanenburg¹, J. Tim Marcus¹, Albert C. Van Rossum¹, Rob M. Heethaar¹

¹VU University Medical Centre, Amsterdam, NL, Netherlands

                  1652.    More Comprehensive Cardiac DENSE MR Imaging by Combination of Short Axis and Long Axis Data

Abbas Nasiraei Moghaddam¹, Han Wen², Morteza Gharib¹

¹California Institute of Technology, Pasadena, California, USA; ²NIH/NHLBI, Bethesda, Maryland, USA

                  1653.    Fast 3D Dense Tracking of Cardiac Material Points Using ZHARP: In-Vivo Validation and Comparison
                                with 3D SF-HARP

Khaled Z. Abd-Elmoniem¹, Matthias Stuber¹, Jerry L. Prince¹

¹Johns Hopkins University, Baltimore, Maryland, USA

                  1654.    Real-Time Single-Shot CINE Imaging of Through-Slice Strain in the Human Heart

Han Wen¹, Eric Bennett¹

¹National Institutes of Health, Bethesda, Maryland, USA

                  1655.    Navigator Gated High Temporal Resolution Tissue Phase Mapping of Myocardial Motion

Bernd André Jung¹, Maxim Zaitsev¹, Jürgen Hennig¹, Michael Markl¹

¹University Hospital, Freiburg, Germany

                  1656.    Toward True Myocardial Plannar Strain Using ZHARP: Experimental In-Vivo Validation

Khaled Z. Abd-Elmoniem¹, Matthias Stuber¹, Jerry L. Prince¹

¹Johns Hopkins University, Baltimore, Maryland, USA

                  1657.    Comparison of Myocardial Velocities Obtained with Magnetic Resonance Phase Velocity Mapping
                                and Tissue Doppler Imaging in Normal Subjects and Patients with Left Ventricular Dyssynchrony

Jana Delfino¹, Mobit Bhasin¹, Robert Cole¹, Angel Leon¹, Robert Eisner¹, John Merlino¹, John Oshinski¹

¹Georgia Institute of Technology/ Emory University, Atlanta, Georgia, USA

                  1658.    The Effect of Noise on the Accuracy of Strain Measurment When Using Strain Encoded (SENC) MRI

Tamer Yousef¹, Nael F. Osman¹

¹Johns Hopkins University, Baltimore, Maryland, USA

                  1659.    VaFA: Replacing CSPAMM

Vinay Manjunath Pai¹, Daniel Kim¹

¹New York University, New York, New York, USA


 

Lung Imaging: Applications

                  1660.    Quantitative Regional Lung Ventilation- Results in 15 Single Lung Transplanted Patients

Hans-Georg Topf¹, P Biondetti², Maren Zapke¹, Rainer Kuth³, M Deimling³, C Chefd´hotel⁴, B Geiger⁵,

Thomas Rupprecht⁶

¹Childrens Hospital, Erlangen, Germany; ²Clinico, Milano, Italy; ³Siemens, Erlangen, Germany; ⁴Siemens, Princeton, U, USA; ⁵Siemens, U, Germany; ⁶Childrens Hospital, Bayreuth, Germany

                  1661.    Is There a Diagnostic Potential of Magnetization Transfer MRI in Patients with Lung Cancer?

Johannes F. T. Arnold¹, Markus Kotas¹, Eberhard D. Pracht¹, Michael Flentje¹, Peter Michael Jakob¹

¹University of Würzburg, Würzburg, Bavaria, Germany

                  1662.    The Role of Hyperpolarized 3-Helium MRI in NSCLC

Rob H. Ireland¹, Mark McJury², Matthew Q. Hatton³, Neil Woodhouse¹, Edwin JR van Beek⁴, Jim M. Wild¹

¹University of Sheffield, Sheffield, UK; ²Belvoir Park Hospital, Belfast, UK; ³Weston Park Hospital, Sheffield, UK; ⁴University of Iowa, Iowa City, Iowa, USA

                  1663.    Ventilation Heterogeneity Indices Computed from Hyperpolarized ³He MRI Captures Differences
                                Between Asthmatic and Non-Asthmatic Lungs

Yang-Sheng Tzeng¹, ², Niral Shah, ¹², Joey Mansour¹, Jessica Gereige¹, George Washko¹, Elliot Israel¹,

Kenneth Lutchen², Mitchell Albert¹

¹Brigham & Women's Hospital, Boston, Massachusetts, USA; ²Boston University, Boston, Massachusetts, USA

                  1664.    Assessing the Temporal Changes of the Regional Ventilation in the Lungs of Asthmatics
                                with Hyperpolarized Helium-3 MR Imaging

Talissa A. Altes¹, ², John J. Battiston², Adam P. Juersivich², John P. Mugler², Thomas AE Platts-Mills²,

Eduard E. de Lange²

¹Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA; ²University of Virginia, Charlottesville, Virginia, USA

                  1665.    Comparison of Diffusion Weighted Helium-3 MRI in Patients with Asthma Versus Those with COPD

Sean B. Fain¹, Tallissa A. Altes², Rafael O'Halloran¹, Ronald L. Sorkness¹, Michael D. Evans¹, Frank R. Korosec¹, Thomas M. Grist¹

¹University of Wisconsin, Madison, Wisconsin, USA; ²University of Pennsylvania, Philadelphia, Pennsylvania, USA

                  1666.    Helium-3 Apparent Diffusion Coefficient MRI Compared to CT in Emphysema Patients

Per Åkeson¹, Sandra Diaz¹, Ingrid Casselbrant¹, Eeva Piitulainen¹, Per Wollmer¹, Göran Pettersson², Peter Magnusson², Barry Peterson³

¹Malmö University Hospital, Malmö, Sweden; ²GE Healthcare, Malmö, Sweden; ³Pfizer Inc., Groton, Connecticut, USA

                  1667.    Velocity Encoding MRI with SENSE: Utility for Assessment of Disease Severity in Pulmonary
                                Emphysema Patients

Munenobu Nogami¹, Yoshiharu Ohno¹, Hisanobu Koyama¹, Daisuke Takenaka¹, Masahiko Fujii¹, Kazuro Sugimura¹

¹Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan

                  1668.    Early Detection of Emphysema by Hyperpolarized Helium-3 MRI Through Measuring
                                Regional Fractional Ventilation

Kiarash Emami¹, Martin Fischer¹, Jianliang Zhu¹, Masaru Ishii², Vahid Vahdat¹, Stephen Kadlecek¹,

John MacDuffie Woodburn¹, Michael E. Friscia¹, JiangSheng Yu¹, Rahim R. Rizi¹, Joseph Shrager¹

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA; ²Johns Hopkins University, Baltimore, Maryland, USA


 

Muscle Spectroscopy

                  1669.    Measurement of Intramyocellular Lipids in Obese Subjects Using Spectroscopic Imaging with High Spatial Resolution

Jan Weis¹, Lars Johansson², Frederic Courivaud³, Anders Karlsson¹, Håkan Ahlström¹

¹Uppsala University Hospital, Uppsala, Sweden, Sweden; ²Astra Zeneca R&D, Uppsala, Sweden, Sweden; ³Philips Medical Systems, Oslo, Norway, Norway

                  1670.    Separation of the Intra- And Extracellular Apparent Diffusion Coefficients (ADC) of Water in
                                Rat Skeletal Muscle Using Spectroscopic MEMRI

Karl G. Helmer¹, John G. Seland², Nils Henninger³, Christopher H. Sotak¹, ³

¹Worcester Polytechnic Institute, Worcester, Massachusetts, USA; ²Norwegian University of Science and Technology, Trondheim, Norway; ³UMass/Memorial Healthcare, Worcester, Massachusetts, USA

                  1671.    In Vivo Quantification of Intramyocellular Lipid in Mouse Hindleg Muscle

Rachida Fissoune¹, Bassem Hiba², Marc Janier², André Briguet¹

¹Laboratoire de RMN CNRS UMR 5012, Lyon, France; ²Animage Plateforme of Small Animal Imaging, Lyon, France

                  1672.    IMCL Changes During Moderate Endurance Exercise as Measured by Three Different Methods

Tom Dresselaers¹, Katrien De Bock¹, Paul Van Hecke¹, Peter Hespel¹

¹K.U.Leuven, Leuven, Belgium, Belgium

                  1673.    MRI Measurement of Advanced Glycation End Products: The MRI Hyperglycemic Damage Index

Andres Rahal¹, Gary D. Fullerton¹

¹The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA

                  1674.    ¹H-MRSI in Human Calf Muscles at 3T: Ordering Effects and Intra-Myocellular Lipids

Peter Vermathen¹, Roland Kreis¹, Chris Boesch¹

¹University & Inselspital, Berne, Switzerland

                  1675.    Response of Insulin-Dependent Type 2 Diabetic Subjects to a 5-Month Exercise Training Program

Henk M.M.L. De Feyter¹, Stephan S.F. Praet², Luc J. van Loon², Jeanine J. Prompers¹, Klaas Nicolay¹

¹Eindhoven University of Technology, Eindhoven, Netherlands; ²Maastricht University, Maastricht, Netherlands

                  1676.    Assesment of the Fat Content of Proximal Femur and Adjacent Muscle in Patients with Osteoarthritis

Trevor S. Ahearn¹, Thomas W. Redpath¹, Richard M. Aspden¹, James D. Hutchison¹, Scott I.K. Semple¹, David J. Knight¹

¹University of Aberdeen, Aberdeen, UK

                  1677.    PPARδ Agonist Treatment Increases Skeletal Muscle Lipid Metabolism Without Altering Mitochondrial Coupling:
                                An In Vivo Magnetic Resonance Spectroscopy Study

Dewen Yang¹, Warren M. Casey¹, Alan R. Olzinski¹, Carolyn Williams¹, Stephen C. Lenhard¹, Jeffrey J. Legos¹, Terrance C. Hawk¹, Susanta K. Sarkar¹, Steve J. Newsholme¹, Beat M. Jucker¹

¹GlaxoSmithKline, King of Prussia, Pennsylvania, USA

                  1678.    The Typical IMCL Distribution Pattern in Rat Tibialis Anterior Muscle Remains Unchanged
                                After High-Fat Diet or Fasting

Henk M.M.L. De Feyter¹, Klaas Nicolay¹, Jeanine J. Prompers¹

¹Eindhoven University of Technology, Eindhoven, Netherlands

                  1679.    Magnetic Resonance Findings and Serum Creatine Kinase Measurements in Acute Human
                                Skeletal Muscle Injury

Tatiana Zaraiskaya¹, Dinesh Kumbhare², Michael D. Noseworthy¹

¹McMaster University, Hamilton, Ontario, Canada; ²St.Joseph's Healthcare, Hamilton, Ontario, Canada

                  1680.    Reproducibility of Muscle Metabolism Parameters in Children Determined by  ³¹P Spectroscopy

Jonathan Fulford¹, Neil Armstrong¹, Alan Barker¹, Deborah Welford¹, Joanne Welsman¹

¹University of Exeter, Exeter, Devon, UK

                  1681.    In Vivo Assessment by 31P-MRS of Skeletal Muscle Mitochondrial Function in Patients on
                                Long-Term Home Parenteral Nutrition

Loris Pironi¹, Emil Malucelli², Cristina Guidetti¹, Caterina Tonon², Claudia Testa², Raffaele Lodi², Bruno Barbiroli², Stefano Iotti²

¹Università di Bologna, Bologna, Italy; ²University of Bologna, Bologna, Italy

                  1682.    OPA1 Mutations Result in a Deficit of In Vivo Mitochondrial ATP Production in Patients with
                                Autosomal Dominant Optic Atrophy

R Lodi¹, C Tonon¹, D Manners¹, E Malucelli¹, C Testa¹, M L. Valentino¹, P Barboni², S Schaich³, S Schimpf³,

B Wissinger³, V Carelli¹, B Barbiroli¹

¹Università di Bologna, Bologna, Italy, Italy; ²Centro Salus, Bologna, Italy, Italy; ³Molekulargenetisches Labor der Universitats-Augenklinik, Tubingen, Germany, Germany

                  1683.    Bioenergetic Defects in Muscles of Polymyositis Patients:  Quantitative MRI and P-31 MRS Investigation

Jing Qi¹, ², Nancy Josephine Olsen¹, ³, Kenneth John Niermann¹, Jane Harting Park¹

¹Vanderbilt University Medical School, Nashville, Tennessee, USA; ²Nanjing Medical University, Nanjing, Jiangsu, People’s Republic of China; ³UT Southwestern Medical School, Dallas, Texas, USA

                  1684.    Intersubject Differences in the Effect of Acidosis on Phosphocreatine Recovery Kinetics After Exercise

Jeanine J. Prompers¹, Henk M.M.L. De Feyter¹, Nicole M.A. van den Broek¹, Larry A.H.J. de Graaf¹, Klaas Nicolay¹

¹Eindhoven University of Technology, Eindhoven, Netherlands

                  1685.    Mitochondrial Capacity and Oxygenation Measured by ³¹P MRS and Near Infrared Spectroscopy
                                in Healthy and Diabetic Subjects

Jonathan Fulford¹, Rajagopalan Sriraman², Claire Ball², John Tooke², Neil Armstrong¹, Angela Shore²

¹University of Exeter, Exeter, Devon, UK; ²Peninsula Medical School, Exeter, Devon, UK

                  1686.    A Quantitative Study of Bioenergetics in Skeletal Muscle Lacking Carbonic Anhydrase III
                                by 31P Magnetic Resonance Spectroscopy

Min Liu¹, Glenn Walter¹, Neeti Pathare¹, Un-jin Zimmerman², Robert E. Forster², Krista Vandenborne¹

¹University of Florida, Gainesville, Florida, USA; ²University of Pennsylvania, Philadelphia, Pennsylvania, USA

                  1687.    Direct Quantification of Lactate and High Energy Phosphates in Exercising Human Skeletal Muscle
                                by Interleaved Localised ¹H DQF, ¹H- And ³¹P STEAM

Martin Meyerspeer¹, Graham J. Kemp², Vladimir Mlynárik¹, Martin Krššák³, Julia Szendroedi¹, Michael Roden⁴, Ewald Moser¹, ³

¹Vienna Medical University, Wien, Austria; ²University of Liverpool, Faculty of Medicine,, Liverpool, UK; ³Medical University of Vienna, Wien, Austria; ⁴Hanusch Hospital Vienna, Wien, Austria

                  1688.    Energy Metabolism in the Extensor Muscles of the Hand and Wrist of Musicians with Overuse Syndrome
                                Studied by 31P-MRS

Angel Moreno-Torres¹, Jaume Rosset², Jesus Pujol³, Silvia Fàbregas²

¹Centre Diagnostic Pedralbes - Cetir Grup Mèdic, Esplugues de Llobregat, Spain; ²Institut de Fisiologia i Medicina de l’Art, Terrassa, Spain; ³Institut d’Alta Tecnologia, Barcelona, Spain

                  1689.    Skeletal Muscle Hydrogen Ion Concentration Stimulates Ventilatory Drive Through Direct Neural Pathways
                                as Shown by ³¹P MRS

Christian Thomas Farrar¹, Mirko I. Hrovat¹, Anne V. LaRaia², Gregory D. Lewis², Paul P. Pappagianopoulos²,

David M. Systrom²

¹Massachusetts General Hospital, Charlestown, Massachusetts, USA; ²Massachusetts General Hospital, Boston, Massachusetts, USA



 

MSK/Body: Spine, Bone, Muscle, Tendon, Misc.

                  1690.    Prediction of Bone Mechanical Properties Using Quantitative MRI

Eveliina Lammentausta¹, Mikko Antero Hakulinen¹, Ilkka Kiviranta², Jukka Sakari Jurvelin¹, ³, Miika Tapio Nieminen⁴

¹University of Kuopio, Kuopio, Finland; ²Jyväskylä Central Hospital, Jyväskylä, Finland; ³Kuopio University Hospital, Kuopio, Finland; ⁴Oulu University Hospital, Oulu, Finland

                  1691.    In-Vivo Micro-MRI of Trabecular Bone in the Ovariectomized Rhesus at 3T

Paul J. McCracken¹, Marie A. Holahan¹, Parker D. Mathers¹, Jacquelynn J. Cook¹, Donald B. Kimmel¹,

Richard Hargreaves¹, Le T. Duong¹, Donald S. Williams¹

¹Merck Research Laboratories, West Point, Pennsylvania, USA

                  1692.    In-Vivo MR Microscopy of Trabecular Structure of a Human Finger Using a Small Permanent Magnet

Nachiko Iita¹, Katsumi Kose¹

¹University of Tsukuba, Tsukuba, Ibaraki, Japan

                  1693.    Trabecular Bone Structure and Anisotropy Studies Via Diffusion-Based MR

Eric Edward Sigmund¹, Hyungjoon Cho¹, Yi-Qiao Song¹, Steve Byrnes, ¹², Peiqiu Chen, ¹², Edward X. Guo³,

Truman Brown³

¹Schlumberger-Doll Research, Ridgefield, Connecticut, USA; ²Harvard University, Cambridge, Massachusetts, USA; ³Columbia University, New York, New York, USA

                  1694.    Measurements of Bone Marrow Proton Relaxation Times and Trabecular Bone Volume Fraction (TBVF)
                                of the Calcaneus for 100 Subjects Using a Compact MRI

Sadanori Tomiha¹, Nachiko Iita¹, Fumi Okada¹, Shinya Handa¹, Katsumi Kose¹

¹University of Tsukuba, Tsukuba, Ibaraki, Japan

                  1695.    Pathophysiology of Bone Marrow Edema: Insights from Dynamic Contrast Enhanced MR Imaging

Edward W. Jung¹, Glenn A. Tung¹, Jonathan P. Dyke², Jonathan H. Lee³, D McK Ciombor¹, Roy K. Aaron¹

¹Brown Medical School, Providence, Rhode Island, USA; ²Weill Cornell Medical College, New York, New York, USA; ³Columbia University Medical School, New York, New York, USA

                  1696.    Contrast-Enhanced MRI with Fat Suppression Using T₁ Dispersion

Sharon E. Ungersma¹, Nathaniel I. Matter¹, Ross D. Venook¹, Albert Macovski¹, Greig C. Scott¹, Garry E. Gold¹, Steven M. Conolly²

¹Stanford University, Stanford, California, USA; ²University of California, Berkeley, Berkeley, California, USA

                  1697.    Water and Fat Suppressed Proton Projection MRI (WASPI) of Rat Femur Bone with Sub-Millimeter Resolution

Yaotang Wu¹, Jerome L. Ackerman², David A. Chesler², Guangping Dai², Mirko I. Hrovat³, Brian D. Snyder⁴,

Ara Nazarian⁴, Melvin J. Glimcher¹

¹Children's Hospital, Boston, Massachusetts, USA; ²Massachusetts General Hospital, Boston, Massachusetts, USA; ³Mirtech Inc, Brockton, Massachusetts, USA; ⁴Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

                  1698.    Trabecular Bone Volume Fraction (TBVF) Measurements of 108 Young Children Using a Compact MRI

Sadanori Tomiha¹, Katsumi Kose¹, Naomi Omi¹, Kayoko Kamemoto¹

¹University of Tsukuba, Tsukuba, Ibaraki, Japan

                  1699.    MRI Characterization of Trabecular Bone Structure by Exploring Bone Microscopic Susceptibility Effect

Shing Chung Cheung¹, Jian Yang¹, Sai Kam Hui¹, Ed Xuekui Wu¹

¹The University of Hong Kong, Pokfulam, Hong Kong, People’s Republic of China

                  1700.    Basic Clinical Imaging Techniques in Prepolarized MRI

Nathaniel I. Matter¹, Greig C. Scott¹, Ross D. Venook¹, Sharon E. Ungersma¹, Thomas Grafendorfer, ^1,2,

John M. Pauly¹, Albert Macovski¹, Steven M. Conolly, ^1,2

¹Stanford University, Stanford, California, USA; ²University of California at Berkeley, Berkeley, California, USA

                  1701.    Prepolarized MRI:  Reducing Susceptibility Artifacts Around Metal Orthopedic Implants Without
                                Sacrificing Image Quality

Ross Venook¹, Nathaniel Matter¹, Meena Ramachandran¹, Sharon Ungersma¹, Garry Gold¹, Nicholas Giori²,

Albert Macovski¹, Greig Scott¹, Steven Conolly³

¹Stanford University, Stanford, California, USA; ²VA Palo Alto Healthcare System, Palo Alto, California, USA; ³U.C. Berkeley, Berkeley, California, USA

                  1702.    Combined Rotational/Translational Motion Correction Using Autofocusing for High-Resolution
                                Trabecular Bone Images

Wei Lin¹, Glenn Ladinsky¹, Felix W. Wehrli¹, Hee Kwon Song¹

¹University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA

                  1703.    Using the Phase for MR Image Segmentation: Application to the Bone of the Knee

Pierrick Bourgeat¹, Peter Stanwell², Saad Ramadan², Sebastien Ourselin¹

¹BioMedia Lab, Autonomous Systems Laboratory, ICT Centre, CSIRO, Sydney, NSW, Australia; ²University of Sydney, Sydney, NSW, Australia

                  1704.    Observation of Anisotropic Properties of Skeletal Muscle in MR Elastography Via a Needle Device

Queenie C. C. Chan¹, Geng Li¹, Richard L. Ehman², Edward S. Yang¹

¹The University of Hong Kong, Pokfulam, Hong Kong, People’s Republic of China; ²Mayo Clinic and Foundation, Rochester, Minnesota, USA

                  1705.    MR-Elastography Reveals Skeletal Muscle Elasticity Changes in Patients with Hypogonadism
                                Prior to Testosterone Substitution and After 6 Months

Katja Brauck¹, Stefan Maderwald¹, Craig Galban¹, Burkhard Herrmann¹, Frank Stock¹, Mark Ladd¹

¹University Hospital Essen, Essen, NRW, Germany

                  1706.    The Effects of Deoxyhemoglobin and Flow Rate on R2' in Hindlimb Perfused Skeletal Muscle

Otto Alexander Sanchez¹, Bruce M. Damon¹

¹Vanderbilt University, Nashville, Tennessee, USA

                  1707.    Dual Gradient-Echo Imaging of Ischemia/Reperfusion in Skeletal Muscle

Bruce M. Damon¹, Jennifer L. Hornberger¹, Jane A. Kent-Braun²

¹Vanderbilt University, Nashville, Tennessee, USA; ²University of Massachusetts, Amherst, Massachusetts, USA

                  1708.    Idiopathic Inflammatory Myositis: Analysis of Magnetic Resonance Imaging Using IDL to Enhance Diagnosis

Charles Edward Hutchinson¹, Harriet Chaney¹, Robert C. Cooper², Judith E. Kilgallon³

¹University of Manchester, Manchester, UK; ²Salford Royal Hospital NHS Trust, Salford, UK; ³Christie Hospital NHS Trust, Manchester, UK

                  1709.    Fast Spatially Resolved Measurement of R2’ and R2 of Each Component of Cancellous Bone Marrow
                                and Correlation of R2’ with Trabecular Bone Volume Fraction (BVF)

Catherine E. Jones¹, Jeremy F. Magland¹, Aranee Techawiboonwong¹, Felix W. Wehrli¹

¹University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA

                  1710.    Potential Metabolic Markers for Intervertebral Disc Pain

Kayvan Keshari¹, John Kurhanewicz¹, Serena Hu¹, Thomas Link¹, Jeffrey Lotz¹, Sharmila Majumdar¹

¹University of California, San Francisco, San Francisco, California, USA

                  1711.    Dynamic Contrast Enhanced MR Imaging and ¹H MR Spectroscopy Study of Post Menopausal Osteoporosis

James Francis Griffith¹, David Yeung¹, Gregory E. Antonio¹

¹The Chinese University of Hong Kong, Shatin, Hong Kong, People’s Republic of China

                  1712.    Magic Angle MR Microscopy and T2 Quantification of Intervertebral Discs
                                Highlights the 3-Dimensional Collagen Structure

Jeff Frank Dunn¹, Tad Foniok², John Robert Matyas¹

¹University of Calgary, Calgary, AB, Canada; ²National Research Council, Calgary, AB, Canada

                  1713.    Apparent Diffusion Coefficient Measurement for Evaluation of Vertebral Normal Variations in the Lumbar Spine

Youichi Sato¹, Eito Kozawa¹, Naoko Nishi¹, Takayuki Hoshino¹, Atsuko Heshiki¹

¹Saitama Medical School, Moroyama-chou, Saitama, Japan

                  1714.    Normal Variations in the Vertebral Appearrence on Opposed-Phase MRI: We Need to Know
                                Normal Bone Marrow Appearrence

Eito Kozawa¹, Waka Mizukoshi¹, Takayuki Hoshino¹, Atsuko Heshiki¹

¹Saitama Medical School, Moroyama-chou, Saitama, Japan

                  1715.    In Vivo MR T1rho Mapping in Lumbar Vertebral Discs at 3T: A Preliminary Study

Xiaojuan Li¹, Eric T. Han², Thomas M. Link¹, Sharmila Majumdar¹

¹University of California at San Francisco, San Francisco, California, USA; ²GE Healthcare Global, Menlo Park, California, USA

                  1716.    Characterization of Intervertebral Disc Degeneration with T1ñ Imaging

Chenyang Wang¹, Walter Witschey¹, Wade Johannessen¹, Sampreet Niyogi¹, Ari Borthakur¹, Dawn M. Elliott¹, Ravinder Reddy¹

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA

                  1717.    Improved Assessment of Degenerative Intervertebral Discs with a Novel Magic Echo Mapping Technique

Walter R.T. Witschey II¹, C Wang¹, Brian K. Bronzo¹, Wade Johannessen¹, Dawn M. Elliott¹, Ravinder Reddy¹

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA

                  1718.    Quantitative 3D- T1_ρ Weighted MRI of Lumbar Spine at 3.0T

Famory -. Niang¹, Sait Kubilay Pakin¹, Mark E. Schweitzer¹, Ravinder R. Regatte¹

¹New York University School of Medicine, New York, New York, USA

                  1719.    In Vivo Assessment of Human Lumbar Disc Degeneration

Ari Borthakur¹, Joshua D. Auerbach¹, Wade Johannessen¹, Carol A. Dolinskas², Richard A. Balderston²,

Dawn M. Elliott¹, Ravinder Reddy¹

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA; ²Pennsylvania Hospital, Philadelphia, Pennsylvania, USA

                  1720.    Quantitative Assessment of Clinical Stage of Aplastic Anemia by Using Dual Phase Chemichal Shift Sequence

Eito Kozawa¹, Waka Mizukoshi¹, Atsuko Heshiki¹

¹Saitama Medical School, Moroyama-chou, Saitama, Japan

                  1721.    Diffusion Tensor Imaging of the Forearm's Nerves

Dan Stein¹, Arnon Neufeld², Moshe Graif², Yaniv Assaf¹, ²

¹Tel Aviv University, Tel Aviv, Israel; ²Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

                  1722.    Diffusion Weighted Magnetic Resonance Spectroscopy of Peripheral Nerve at 18.8T

Jacob Ellegood¹, Ryan T. McKay¹, Chris C. Hanstock¹, Christian Beaulieu¹

¹University of Alberta, Edmonton, Alberta, Canada

                  1723.    Tendon Imaging Using 3D Ultrashort TE Scanning

Jürgen Rahmer¹, Peter Börnert¹, Clemens Bos², Jan Groen², Giel Mens²

¹Philips Research Laboratories, Hamburg, Germany; ²Philips Medical Systems, Best, Netherlands

                  1724.    Diffusion MRI of Denervated Skeletal Muscle for Early Diagnosis of Peripheral Nerve Injury

Eiko Yamabe¹, Toshiyasu Nakamura¹, Koichi Oshio¹, Yoshito Kikuchi², Hiroyasu Ikegami¹, Yoshiaki Toyama¹

¹School of Medicine, Keio University, Tokyo, Japan; ²Saitama Municipal Hospital, Saitama, Japan

                  1725.    Determination of Anisotropic Velocity Profiles in Muscle Using Wave-Guide Constrained
                                Magnetic Resonance Elastography

Anthony Joseph Romano¹, Philip B. Abraham¹, Stacie I. Ringleb², Phillip J. Rossman², Joseph A. Bucaro¹,

Richard L. Ehman²

¹Naval Research Laboratory, Washington, District of Columbia, USA; ²Mayo Clinic, Rochester, Minnesota, USA

                  1726.    Fanctional Imaging of Muscle Contraction Caused by Electric Stimulation

Yasuharu Watanabe¹, Keisaku Kimura², Masahiro Umeda², Ichio Aoki², Masahiro Higuchi², Chuzo Tanaka²,

Shoji Naruse³

¹Meiji School of Oriental Medicine, Suita, Osaka, Japan; ²Meiji University of Oriental Medicine, Nantan, Kyoto, Japan; ³Radiology, Kyoto, Kyoto, Japan

                  1727.    Skeletal Muscle Degeneration and Regeneration Following Femoral Artery Ligation in the Mouse,
                                as Monitored Using Diffusion Tensor Imaging

Anneriet M. Heemskerk¹, Glenda S. van Bochove¹, Maarten R. Drost², Gustav J. Strijkers¹, Klaas Nicolay¹

¹Eindhoven University of Technology, Eindhoven, Netherlands; ²Maastricht University, Maastricht, Netherlands

                  1728.    Dynamic Changes in DTI Eigenvalues and Eigenvectors Following Ischemia-Induced Skeletal Muscle Damage

Anneriet M. Heemskerk¹, Gustav J. Strijkers¹, Glenda S. van Bochove¹, Maarten R. Drost², Klaas Nicolay¹

¹Eindhoven University of Technology, Eindhoven, Netherlands; ²Maastricht University, Maastricht, Netherlands

                  1729.    Diffusion Tensor MRI for the In Vivo Determination of Skeletal Muscle Architecture in Two Ankle Angles

Anneriet M. Heemskerk¹, Gustav J. Strijkers¹, Maarten R. Drost², Klaas Nicolay¹

¹Eindhoven University of Technology, Eindhoven, Netherlands; ²Maastricht University, Maastricht, Netherlands

                  1730.    Quantitative Characterization of Mouse Calf Muscle Degeneration After Left Sciatic Nerve
                                Axotomy with Magnetic Resonance Imaging

Jiangyang Zhang¹, Gang Zhang¹, Susumu Mori¹, ², Kazim A. Sheikh¹

¹Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; ²Kennedy Krieger Institute, Baltimore, Maryland, USA

                  1731.    Effect of Skeletal Muscle T1 Changes on the Determination of Perfusion by Arterial Spin Labelling
                                Combined to NMR Imaging

Céline Baligand¹, Didier Bertoldi¹, Claire Wary¹, Pierre G. Carlier¹

¹Institut de Myologie, Paris, France

                  1732.    Radiologic Evaluation of Hip Measurements: MR Versus X-Ray Correlation

Sarah Ann Shock¹, Andy I. Abeles², Mark E. Schweitzer¹, Robert Meislin¹, James Babb¹, Charbel Isaak¹

¹NYU, New York, New York, USA; ²University of Missouri, Columbus, Missouri, USA

                  1733.    The Study of Ulnar Variance with High-Resolution MRI: Correlation with Triangular
                                Fibrocartialge Complex and Cartilage of Ulnar Side of the Wrist

Hiroshi Yoshioka¹, Toshiokazu Tanaka², Teruko Ueno³, John A. Carrino¹, Carl S. Winalski¹, Philipp Lang¹,

Barbara N. Weissman¹

¹Brigham and Women's Hospital, Boston, Massachusetts, USA; ²Mayo Clinic, Rochester, Minnesota, USA; ³Iwate Medical School, Morioka, Iwate, Japa

                  1734.    The Value of MR Imaging Using Microscopy Coil in Evaluation of Finger Masses: Correlation
                                with Pathologic and Surgical Findings

Jung-Ah Choi¹, In Sook Lee², Joo Han Oh¹, Heung Sik Kang¹

¹Seoul National University Bundang Hospital, Seongnam, Gyeongi-do, Republic of Korea; ²Pusan National University College of Medicine, Pusan, Republic of Korea

                  1735.    Joint Arthrography with MRI Image Overlay: Porcine Trials

Gregory Scott Fischer¹, Anton Deguet¹, Csaba Csoma¹, Russell H. Taylor¹, Laura Fayad¹, S James Zinreich¹,

Gabor Fichtinger¹

¹Johns Hopkins, Baltimore, Maryland, USA

                  1736.    Feasibility of MR Guided Direct Arthrography

Suzanne Wakeley¹, Martin J. Graves¹, Philip Bearcroft¹, Richard T. Black¹, Elzare van Rooyen¹, David John Lomas¹

¹University of Cambridge & Addenbrooke's Hospital, Cambridge, UK

                  1737.    High SNR, Microscopic Imaging of Skin Lesions

Stefan Maderwald¹, Susanne C. Ladd¹, Mark E. Ladd¹, Frank Stock¹, Thomas Paul¹, Anja Liffers², Jörg Barkhausen¹, Thilo Gambichler², Harald H. Quick¹

¹University Hospital Essen, Essen, Germany; ²Ruhr-University Bochum, Bochum, Germany

                  1738.    Abnormal Post-Ischemic Reperfusion Patterns in the Skeletal Muscle of Serotonin Deficient Mice
                                Identified by Arterial Spin Labeling Coupled to SSFSE Imaging

Didier Bertoldi¹, Yves Fromes², Cécile Fligny³, Francine Cote³, Guilan Vodjdani³, Pierre G. Carlier¹

¹Institut de Myologie, Paris, France; ²Institut de myologie, Paris, France; ³UMR 7091, Paris, France

                  1739.    Application of 1H and 31P Single Point Imaging (SPI) of Teeth Using Silent Gradients

Marco L.H. Gruwel¹, Peter Latta¹, Marta Tanasiewicz², Vyacheslav Volotovskyy¹, Milos Sramek³, Boguslaw Tomanek¹

¹NRC-CNRC, Winnipeg, MB, Canada; ²Silesia Medical Academy, Katowice, Poland; ³OAW Visualisierung, Vienna, Austria

                  1740.    3D Visualisation of the Tooth Caries - Potential New Area for Biomedical Application of MRI

Wladyslaw Piotr Weglarz¹, Marta M. Tanasiewicz², Tomasz W. Kupka², Marco LH Gruwel³, Cezary Przeorek⁴,

Andrzej Jasinski¹, Boguslaw Tomanek³

¹Institute of Nuclear Physics, Krakow, Poland; ²Medical University of Silesia, Bytom, Poland; ³NRC Institute of Biodiagnostics, Winnipeg, Manitoba, Canada; ⁴Comprehensive Cancer Centre, Gliwice, Poland

                  1741.    NMR Study of Gallstones from Benign and Malignant Gallbladders

Madhulika Srivastava¹, ², G. A. Nagana Gowda², Ajay Sharma³, Ashish Gupta², V. K. Kapoor³, C. L. Khetrapal²

¹Department of Surgery, Lucknow, Uttar Pradesh, India; ²Centre of Biomedical Magnetic Resonance, Lucknow, Uttar Pradesh, India; ³Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India


 

Cancer Models: Detection, Diagnoses, and Staging

                  1742.    Functional Colonoscopy Using Dark Lumen DCE-MRI

Christopher Chad Quarles¹, James Oliver McIntyre¹, David Lee Gorden¹, Martin Lepage, ^1,2, Thomas Edison Yankeelov¹, Ronald R. Price¹, Lynn M. Matrisian¹, John Christopher Gore¹

¹Vanderbilt University, Nashville, Tennessee, USA; ²University Sherbrooke, Sherbrooke, QC, Canada

                  1743.    Tumor-Antigen Targeted Imaging of Pancreatic Adenocarcinoma

Zdravka Medarova¹, Wellington Pham¹, Young Kim¹, Guangping Dai¹, Anna Moore¹

¹Massachusetts General Hospital, Charlestown, Massachusetts, USA

                  1744.    A Dendrimer Based Contrast Agent for MR Imaging of Her-2/neu Receptors by a Three-Step
                                Pretargeting Approach

Wenlian Zhu¹, Baasil Okollie¹, Zaver M. Bhujwalla¹, Dmitri Artemov¹

¹Johns Hopkins University, Baltimore, Maryland, USA

                  1745.    Characterization of Rat Glioma Models by Magnetic Resonance Angiography

Sabrina Doblas¹, Yasvir Tesiram¹, Debra Saunders¹, Quentin Pye¹, Preeti Kshirsagar¹, Rheal A. Towner¹

¹Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA

                  1746.    Dynamic Contrast Magnetic Resonance Imaging Detects Premalignant High-Grade
                                Dysplasia in Epithelial Carcinogenesis

Joel Richard Garbow¹, John Engelbach¹, Krista Olson¹, Jeffrey Arbeit¹

¹Washington University, St. Louis, Missouri, USA

                  1747.    Early Detection of Prostate Neoplasm Using Pixel-By-Pixel R1 Mapping Following Gd(ABE-DTTA)
                                Administration in TRAMP Mice

Pal Kiss¹, Ada Elgavish¹, Isam-Eldin A. Eltoum¹, Pal Suranyi¹, Huadong Zeng¹, Tamas Simor¹, Balazs Ruzsics¹, Gabriel A. Elgavish¹

¹University of Alabama at Birmingham, Birmingham, Alabama, USA

                  1748.    Improved Prostate Cancer Detection Using DCE-MRI and Probability Maps

Xinrui Huang¹, Qiang Wang², Yufeng Xu³, Xiaoying Wang³, Shanglian Bao¹

¹The Key Lab of Medical Physics and Engineering,Peking University, Beijing, People’s Republic of China; ²The Medical School of Peking University, Beijing, People’s Republic of China; ³The First Hospital of Peking University, Beijing, People’s Republic of China

                  1749.    Tumor Growth with Anisotropic Diffusion

Ashok Kumar¹, Alma Gregory Sorensen¹

¹Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA

                  1750.    Longitudinal MR Studies of Human Mammary Carcinoma Cell Brain Metastasis in Nude Mice at 7 Tesla

Rui Simoes¹, ², Antonio Martinez³, Sebastián Cerdán⁴, Angels Sierra³, Carles Arús¹

¹Universitat Autònoma de Barcelona, Barcelona, Spain; ²Universidade de Coimbra, Coimbra, Portugal; ³Institut de Recerca Oncològica, Barcelona, Spain; ⁴Instituto de Investigaciones Biomédicas Alberto Sols UAM-CSIC, Madrid, Spain

                  1751.    High Field MR Imaging of Pre-Invasive Pancreatic Carcinoma in a Transgenic Mouse Model

Palamadai Nilakantan Venkatasubramanian¹, Paul Grippo², Richard Knop³, Alice Wyrwicz¹

¹ENH Research Institute, Evanston, Illinois, USA; ²Northwestern University School of Medicine, Chicago, Illinois, USA; ³Evanston Northwestern Healthcare, Evanston, Illinois, USA

                  1752.    Characterization and Early Detection of Liver Metastasis by fMRI

Yifat Edrei¹, Eitan Gross¹, Eli Pikarsky¹, Eithan Galun¹, Rinat Abramovitch¹

¹Hadassah Hebrew University Medical Center, Jerusalem, Israel

                  1753.    Semi-Automated Lymph Node Staging Using LN-MRI

Gozde Unal¹, Greg Slabaugh¹, Bernd Wachmann¹, Thomas Fuchs¹, Tong Fang¹, Robert Krieg², Ravi Seethamraju², Mukesh Harisinghani³, Ralph Weissleder³

¹Siemens Corporate Research, Princeton, New Jersey, USA; ²Siemens Medical Solutions, Erlangen, Germany; ³Massachusetts General Hospital, Boston, Massachusetts, USA

                  1754.    Multiparametric Imaging of Tumor Boundaries Using Linear Discriminant Analysis

Marina Benito-Vicente¹, Pilar López-Larrubia¹, Laura Barrios², Patricia Sanchez-García¹, Sebastián Cerdán¹,

María Luisa García-Martín¹

¹Instituto de Investigaciones Biomédicas “Alberto Sols” CSIC/UAM, Madrid, Spain; ²CSIC, Madrid, Spain

                  1755.    Comparison of Spectral Spatial PRESS with TE Averaged PRESS in Breast Choline Detection

Fei Sun¹, Lu Hong², Guang Cao³

¹GE Healthcare China, Beijing, People’s Republic of China; ²Tianjin Cancer Hospital, Tianjin, People’s Republic of China; ³GE Healthcare China, Hong Kong, People’s Republic of China

                  1756.    Fatty Acid Speciation by NMR Spectroscopy and Potential Methods for Liver Cancer Diagnaosis

Yasvir A. Tesiram¹, Debra Saunders¹, Jeff Griffitts¹, Rheal A. Towner¹

¹Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA

                  1757.    1H-MR Spectroscopy of the Prostate at 3.0 T with a Phase-Array Surface Coil

Frank Traeber¹, Nuschin Morakkabati-Spitz¹, Ursula Jaeger¹, Mike P. Wattjes¹, Patrick Bastian¹, Alexander Schmitz¹, Jürgen Gieseke², Okan Guer¹, Wolfgang Block¹, Renate Bloemer¹, Hans H. Schild¹

¹University of Bonn, Bonn, Germany; ²Philips Medical Systems, Best, Netherlands

                  1758.    Line Scan Echo Planar Spectroscopic Imaging of the Prostate at 3T: Feasibility Study

Yasushi Kaji¹, Kagayaki Kuroda², Ryo Sugihara¹, Kazuro Sugimura¹

¹Kobe Univ. Graduate School of Medicine, Kobe, Hyogo, Japan; ²Institute of Biomedical Research and Innovation, Kobe, Hyogo, Japan

                  1759.    Differentiation of Low from High Grade Oligodendrogliomas by 1H Magnetic Resonance
                                Spectroscopy Imaging and Perfusion Weighted Imaging

Sanjeev Chawla¹, Sumei Wang¹, John H. Woo¹, Jiongjiong Wang¹, Donald M. O' Rourke¹, Kevin Judy¹,

Michael S. Grady¹, Ranald L. Wolf¹, Elias R. Melhem¹, Harish Poptani¹

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA

                  1760.    Dynamic Contrast-Enhanced MR and Proton MR Spectroscopic Imaging in Localizing Prostate Cancer

Jurgen J. Futterer¹, Tom W.J. Scheenen¹, Stijn W.T.P.J. Heijmink¹, Christina A. Hulsbergen-van de Kaa¹,

J. Alfred Witjes¹, Arend Heerschap¹, Jelle O. Barentsz¹

¹UMCN, Nijmegen, Gld, Netherlands

                  1761.    Imaging Findings of Castleman Disease of the Abdomen and Pelvis

Liangping Zhou¹, Weijun Peng¹, Peihua Wang¹, Bei Zhang², Yubao Guan³, Kangrong Zhou⁴

¹Cancer Hosipital of Fudan University, Shanghai, People’s Republic of China; ²Shanghai Ruijin Hosipital, Shanghai, People’s Republic of China; ³1stHospital of Guangzhou  College, Guangzhou, People’s Republic of China; ⁴Zhongshan Hosipital of Fudan University, Shanghai, People’s Republic of China

Cancer Models: Predicting and Monitoring Therapy Response with MRI

                  1762.    Characterization of the Tumor Micro-Environment After Administration of Glucocorticoids to
                                Understand Their Radiosensitization Effect

Nathalie Crokart¹, Bénédicte F. Jordan¹, Christine Baudelet¹, Gregory O. Cron¹, Julie Hotton¹, Kim Radermacher¹, Vincent Gregoire¹, Nelson Beghein¹, Philippe Martinive¹, Olivier Feron¹, Bernard Gallez¹

¹Université Catholique de Louvain, Brussels, B, Belgium

                  1763.    Botulinum Toxin Potentiates Cancer Radiotherapy and Chemotherapy

Réginald Ansiaux¹, Christine Baudelet¹, Greg O.Cron¹, Jérôme Segers¹, Chantal Dessy¹, Philippe Martinive¹,

Julie De Wever¹, Julien Verrax¹, Valérie Wauthier¹, Nelson Beghein¹, Vincent Grégoire¹, Pedro Buc Calderon¹,

Olivier Feron¹, Bernard Gallez¹

¹Catholic University of Louvain, Woluwe, Brussels, Belgium

                  1764.    Botulinum Toxin Increases Tumor Uptake of Gemcitabine Chemotherapy as Measured with Fluorine Spectroscopy

Greg O. Cron¹, Nelson Beghein¹, Réginald Ansiaux¹, Bernard Gallez¹

¹Catholic University of Louvain, Brussels, Belgium

                  1765.    Blood Flow Increase in 9L Brain Tumors in Response toRadiation Therapy and Chemotherapy as
                                Detected by Arterial Spin Labeling MRI

Amandeep Salhotra¹, Phillip Zhe Sun¹, ², Peter C.M. van Zijl¹, ², Zaver Bhujwalla¹, Bachchu Lal², John Laterra¹, ², Jinyuan Zhou¹, ²

¹Johns Hopkins University, Baltimore, Maryland, USA; ²KKI, Baltimore, Maryland, USA

                  1766.    Carbogen Breathing Differentially Enhances Blood Plasma Volume and 5-Fluorouracil Uptake in
                                Two Murine Colon Tumor Models with Distinct Vascular Structures

Hanneke van Laarhoven¹, Giulio Gambarota¹, Jasper Lok¹, Martin Lammens¹, Yvonne Kamm¹, Theo Wagener¹, Cornelis Punt¹, Albert van der Kogel¹, Arend Heerschap¹

¹University Medical Centre Nijmegen, Nijmegen, Gld., Netherlands

                  1767.    Application of Multiple-Quantum-Filtered 23Na MRI to Monitor Chemotherapeutic Response in RIF-1 Tumors

Andriy Babsky¹, Hong Zhang¹, Shahryar K. Hekmatyar¹, Gary Hutchins¹, Navin Bansal¹

¹Indiana University, Indianapolis, Indiana, USA

                  1768.    Evolution of the Tumor Oxygenation and Perfusion at the Early Stage of the Treatment with SU5416,
                                an Inhibitor of Flk-1 Tyrosine Kinase

Réginald Ansiaux¹, Christine Baudelet¹, Greg O.Cron¹, Philippe Martinive¹, Julie De Wever¹, Vincent Grégoire¹, Olivier Feron¹, Bernard Gallez¹

¹Catholic University of Louvain, Woluwe, Brussels, Belgium

                  1769.    Comprehensive Magnetic Resonance Monitoring of Tumoricidal Effect of a Vascular Targeting Agent
                                in a Rodent Liver Metastatic Model

Yicheng Ni¹, Xihe Sun¹, ², Feng Chen¹, ³, Frederik De Keyzer¹, Vincent Vandecaveye¹, Willy Landuyt¹,

Paul Van Hecke¹, Hide Bosmans¹, Guy Marchal¹

¹University Hospital, Catholic University of Leuven, Leuven, B-3000, Belgium; ²Affiliated Hospital, Weifang Medical University, Weifang, Shandong, People’s Republic of China; ³Zhong Da Hospital, Southeast University, Nanjing, Jiangsu, People’s Republic of China

                  1770.    Early Response Measurements of NGR-TNF Efficacy Using MR and Immunohistochemical Methods

Hanneke van Laarhoven¹, Giulio Gambarota¹, Cornelis Punt¹, Jasper Lok¹, Ilja Verhagen¹, Angelo Corti²,

Salvatore Toma³, Corrado Gallo Stampino³, Albert van der Kogel¹, Arend Heerschap¹

¹University Medical Centre Nijmegen, Nijmegen, Netherlands; ²San Raffaele H Scientific Institute, Milan, Italy; ³MolMed S.p.A, Milan, Italy

                  1771.    TOOKAD Photodynamic Therapy of Orthotopic PC3-MM2  Prostate Tumors in Nude Rats :
                                Investigation Using  BOLD-MRI, Diffusion-Weighted-MRI and  Dynamic-Contrast Enhanced MRI

Dominique Blanc¹, Henri Ficheux¹, Nathalie Just², Nicolas Guilbaud²

¹NEGMA-LERADS, Magny-les-Hameaux, France; ²Oncodesign Biotechnology, Dijon, France

                  1772.    MRI Assessment of a Treatment for Non-Small Cell Lung Cancer in a Mouse Model

Ruqayyah M. Al-Hashem¹, Hongbin Ji², Mitchell S. Albert¹, Kwok-Kin Wong², Yanping Sun¹

¹Brigham & Women's Hospital, Boston, Massachusetts, USA; ²Dana Farber Cancer Institute, Boston, Massachusetts, USA

                  1773.    Ranpirnase-Induced Changes in Blood Flow, Lactate, and ATP Levels in A549 Human NSCLC
                                Measured by Noninvasive Near Infra-Red Spectroscopy and Magnetic Resonance Spectroscopy

Sergey Magnitsky¹, Ulas Sunar¹, Matthew Milkevitch¹, Arjun G. Yodh¹, Intae Lee¹

¹University of Pennsylvania, Philadelphia, PA 19104-6069, USA

                  1774.    A ¹H MRS Study of Tumour Overexpression of Dimethylarginine Dimethylaminohydrolase (DDAH)
                                and Response to Taxotere

Basetti Madhu¹, Saira Ansari¹, John R. Griffiths¹, Guy St.J. Whitley¹, Simon P. Robinson¹

¹St. George's, University of London, London, England, UK

                  1775.    Real-Time Imaging of Emerging Resistance During Cancer Therapy

Kuei C. Lee¹, Daniel E. Hall¹, Benjamin A. Hoff¹, Bradford A. Moffat¹, Surabhi Sharma¹, Thomas L. Chenevert¹, Charles R. Meyer¹, Wilbur R. Leopold², Timothy D. Johnson¹, Alnawaz Rehemtulla¹, Brian D. Ross¹

¹University of Michigan Medical School, Ann Arbor, Michigan, USA; ²Molecular Imaging Research Preclinical Services, Ann Arbor, Michigan, USA

                  1776.    The ADC Value in Esophageal Caners on Diffusion-Weighted MR Images for Predicting Effect
                                of Chemoradiotherapy

Takashi Koyama¹, Shigeaki Umeoka¹, Tsuneo Saga¹, Ken Tamai¹, Go Watanabe¹, Masahiro Hiraoka¹, Kaori Togashi¹

¹Kyoto University, School of Medicine, Kyoto, Japan

                  1777.    In Vivo MR Diffusion Investigation of Murine Tumors with Bacteria Infiltration

Kaung-Ti Yung¹, Xiangjin Song¹, Gabrielle Ramus¹, Vitaly Chibisov¹, Qiuhong He¹

¹University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA

Clinical MRS in Cancer

                  1778.    Characterization of High Grade Gliomas Using TE-Averaged PRESS at 3 T

Yan Li¹, Radhika Srinivasan¹, Susan M. Chang¹, Sarah J. Nelson¹

¹University of California, San Francisco, California, USA

                  1779.    Quantitative SENSE Spectroscopy of Gliomas at 3T

Esin Ozturk-Isik¹, ², Albert P. Chen¹, ², Jason C. Crane¹, Duan Xu¹, Eric T. Han³, Daniel B. Vigneron¹, ²,

Soonmee Cha¹, Susan M. Chang¹, Sarah J. Nelson¹, ²

¹University of California, San Francisco, California, USA; ²UCSF/UCB Joint Graduate Group in Bioengineering, San Francisco, California, USA; ³GE Healthcare Global Applied Science Laboratory, Menlo Park, California, USA

                  1780.    Fast Nosologic Imaging of the Brain

Maarten De Vos¹, Teresa Laudadio¹, Arjan W. Simonetti¹, Sabine Van Huffel¹, Arend Heerschap²

¹K.U.Leuven, Leuven, Belgium; ²U.M.C.Nijmegen, Nijmegen, Netherlands

                  1781.    Enhanced  Detection of Glutamine (Gln) and Glutamate (Glu) with 1H MRS Using Single
                                Voxel STEAM: Their Potential to Stage Brain Tumors

Matthew R. Amans¹, Quan Jiang², Yang Xuan¹, Shireen Hm-Meeran¹, Lucia J. Zamorano¹, Murali Guthikonda¹, Geoffrey Barger¹, Vivek Sehgal¹, Jiani Hu¹

¹Wayne State University, Detroit, Michigan, USA; ²Henry Ford Hospital, Detroit, Michigan, USA

                  1782.    Brain Tumour Diagnosis and Prognosis by In Vivo 1H MRS and Ex Vivo Metabolomic and
                                Genomic Data. A Prospective Study as Part of ETUMOUR (FP6-2002-LSH503094)

Daniel Monleon¹, Carmen Martinez-Bisbal¹, Beatriz Martinez-Granados¹, Vicent Esteve¹, Eva Piñero-Sagredo¹,

Ruben Ferrer-Luna¹, Manuel Mata², Jose Piquer³, Luis Marti-Bonmati⁴, Bernardo Celda¹

¹Universitat de Valencia, Burjassot, Valencia, Spain; ²University of Valencia, Valencia, Spain; ³Hospital de la Ribera, Alzira, Valencia, Spain; ⁴Clinica Quiron, Valencia, Spain

                  1783.    In Vivo MRS Metabolic Profiles of Human Brain Metastases from Different Primary Cancers

Torill Eidhammer Sjøbakk¹, Roar Johansen¹, Tone Frost Bathen¹, Ursula Sonnewald¹, Kjell Arne Kvistad²,

Steinar Lundgren, ¹², Ingrid Susanne Gribbestad¹

¹Norwegian University of Science and Technology, Trondheim, Norway; ²St.Olavs University Hospital Trondheim, Trondheim, Norway

                  1784.    Sequential MRSI and DWI Study for Early Assessment of Response of Breast Cancer
                                to Neo-Adjuvant Chemotherapy: A Pilot Study

K A. Danishad¹, V Seenu¹, S Roell², M Vorbuchner², N R. Jagannathan¹

¹All India Institute of Medical Sciences, New Delhi, Delhi, India; ²Siemens Medical Solutions, Erlangen, Germany

                  1785.    Simultaneous Detection of Choline and Other Metabolites Using SEE-SelMQC for Spectroscopic
                                Imaging of Human Breast Cancer

Qiuhong He¹, Xiaohong Joe Zhou²

¹Univerisity of Pittsburgh, Pittsburgh, Pennsylvania, USA; ²University of Illinois Medical Center, Chicago, Illinois, USA

                  1786.    MR-Determined Metabolic Phenotype of Breast Cancer Predicts Lymphatic Spread, Grade and Hormone Status

Tone Frost Bathen¹, Line Rørstad Jensen¹, Beathe Sitter¹, Hans Fjøsne², Jostein Halgunset¹, David E. Axelson³,

Ingrid Susanne Gribbestad¹, Steinar Lundgren, ¹²

¹NTNU, Trondheim, Norway; ²St. Olavs University Hospital, Trondheim, Norway; ³MRI_Consulting, Kingston, Ontario, Canada

                  1787.    High-Resolution Magic Angle Spinning (HRMAS) 1H MRS Detects Biomarkers in Pancreatic Cancer

Haihui Cao¹, ², Gregory Y. Lauwers², Carlos Fernandez-del Castillo², Andrew L. Warshaw², A. Aria Tzika¹, ²

¹Massachusetts General Hospital and Shriners Institute, Harvard Medical School, Boston, Massachusetts, USA; ²Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

                  1788.    Potential of 3D ¹H MRSI Localization of Prostate Cancer to Direct TRUS Guided Biopsy in Patients
                                with PSA 4 – 10 Ng/mL

Virendra Kumar¹, N R. Jagannathan¹, Rajeev Kumar¹, S C. Das¹, Lokesh Jindal¹, Sanjay Thulkar¹, S Dutta Gupta¹,

S N. Dwivedi¹, A K. Hemal¹, N P. Gupta¹

¹All India Institute of Medical Sciences, New Delhi, Delhi, India

                  1789.    1D High Resolution Magic Angle Spinning Total Correlation Spectroscopy of Prostate Cancer Tissues

Mark Gunnard Swanson¹, Andrew S. Zektzer¹, Kayvan R. Keshari¹, Laura Tabatabai¹, Thomas Butler¹,

John Kurhanewicz¹

¹UCSF, San Francisco, California, USA

                  1790.    Potential of ¹H MR Spectroscopic Imaging to Predict Negative Biopsy in Men with PSA < 10 Ng/mL

Virendra Kumar¹, Rajeev Kumar¹, Lokesh Jindal¹, Rishi Nayyar¹, Sanjay Thulkar¹, S Dutta Gupta¹, S N. Dwivedi¹,

A K. Hemal¹, N P. Gupta¹, N R. Jagannathan¹

¹All India Institute of Medical Sciences, New Delhi, Delhi, India

                  1791.    3D ¹H MRSI Based TRUS Guided Biopsies in Men with Suspected Prostate Cancer

Virendra Kumar¹, N R. Jagannathan¹, Rajeev Kumar¹, Lokesh Jindal¹, S C. Das¹, Rishi Nayyar¹, Sanjay Thulkar¹,

S Dutta Gupta¹, S N. Dwivedi¹, A K. Hemal¹, N P. Gupta¹

¹All India Institute of Medical Sciences, New Delhi, Delhi, India;

                  1792.    Single Voxel and Chemical Shift Imaging (CSI) of Soft Tissue Sarcomas

Virendra Kumar¹, Madhabanda Kar¹, K A. Danishad¹, S V.S Deo¹, N K. Shukla¹, U Sharma¹, S Dattagupta¹, S Dey¹,

S Tulkar¹, N R. Jagannathan¹

¹All India Institute of Medical Sciences, New Delhi, Delhi, India

Clinical Applications in Cancer

                  1793.    Multi-Contrast Whole-Body 2D Axial MR Imaging During Continuous Table Movement for Tumor Staging

Katja Brauck¹, Michael Zenge¹, Frank Stock¹, Ladd Mark¹, Florian Vogt¹, Joerg Barkhausen¹

¹University Hospital Essen, Essen, NRW, Germany

                  1794.    3D MR Sialography  as a Tool to Visualize and Investigate Radiation-Induced Changes to the
                                Salivary Glands and Ducts in Patients

Eleftheria Astreinidou¹, C.P.J Raaijmakers¹, J. Roesink¹, C Terhaard¹, L. W. Bartels¹

¹University Medical Center, Utrecht, Netherlands

                  1795.    Three-Dimensional Proton MR Spectroscopic Imaging of Human Breast Lesions

Michael A. Jacobs¹, ², Mari Smith³, Nagi Khouri¹, David A. Bluemke¹, Peter B. Barker³

¹Johns Hopkins School of Medicine, Baltimore, Maryland, USA; ²Sidney Kimmel Dept of Oncology, Baltimore, Maryland, USA; ³Kennedy Krieger Institute, Baltimore, Maryland, USA

                  1796.    Evaluation of CADstream^TM for Serial Automated Breast Tumor Volume Measurements in Patients
                                Undergoing Neoadjuvant Chemotherapy for Breast Cancer

Bonnie N. Joe¹, Alexander Urioste², Kiarash Vahidi¹, Jessica Gibbs¹, Evelyn Proctor¹, Zakar Siraj¹, Ying Lu¹,

Nola Hylton¹

¹University of California, San Francisco, San Francisco, California, USA; ²University of California, San Diego, San Diego, California, USA

                  1797.    Characterisation of Breast Tumors with a Model-Independent Analysis of Bolus-Tracking MRI

Smitha Makkat¹, Steven Sourbron¹, Vally Dewilde¹, Filip De Ridder¹, Rob Luypaert¹, Tadeusz Stadnik¹, Johan De Mey¹

¹Vrije Universiteit Brussel, Brussels, Belgium

                  1798.    Comparison of Whole Body MRI and Whole Body PET-CT for Staging of Advanced
                                Bronchial Carcinoma – Initial Results

Christian Plathow¹, Susanne Eschmann¹, Philipp Aschoff¹, Vanessa Heinrich¹, Jürgen Schaefer¹, Claus Claussen¹, Thomas Hehr¹, Christina Pfannenberg¹ , Heinz-Peter Schlemmer¹

¹Eberhard-Karls University, Tuebingen, Baden-Wuerttemberg, Germany

                  1799.    Usefulness of Diffusion-Weighted MR Image in Detecting Pancreas Cancer: Comparative Analyses
                                with T1, T2-Weighed MR Images

Noriaki Muraoka¹, Hirohiko Kimura¹, Hidemasa Uematsu¹, Yasuhiro Fujiwara¹, Isao Yamaguchi¹, Harumi Itoh¹

¹University of Fukui, Fukui, Japan

                  1800.    High-B-Value Diffusion-Weighted MR Imaging of Gastric Cancer: By Segmented Breath-Hold Technique

Xiao Peng Zhang¹, Lei Tang², Ying Shi Sun¹, Fei Sun³

¹Beijing Cancer Hospital & Peking University School of Oncology, Beijing, People’s Republic of China; ²Beijing Cancer Hospital, School of Oncology, Peking University, Beijing, People’s Republic of China; ³MR Modality, GE Healthcare, China, Beijing, People’s Republic of China

                  1801.    Abdominal Imaging with Extended Field of View in Rectal Cancer Using a Continuously Moving Table:
                                A Feasibility Study

Gregor Sommer¹, Ute Ariane Ludwig¹, Hans-Peter Fautz¹, Oliver Schäfer¹

¹University Hospital Freiburg, Freiburg, Germany

                  1802.    Multi-Parametric MR Imaging of Prostate Cancer at 3T

Albert P. Chen¹, ², Joonmi Oh¹, Eric T. Han³, Duan Xu¹, ², John Kurhanewicz¹, ², Daniel B. Vigneron¹, ²

¹UCSF, San Francisco, California, USA; ²UCSF/UCB, San Francisco, California, USA; ³GE Healthcare, Menlo Park, California, USA

                  1803.    Metabolic Profiling of Preinvasive and Invasive Cervical Cancer Using 1H and 31P Magic Angle Spinning MRS

Sonali S. De Silva¹, Geoffrey S. Payne¹, Patrick Soutter², Nandita M. Desouza¹

¹Institute of Cancer Research, Sutton, Surrey, UK; ²Hammersmith Hospital, London, UK

                  1804.    Deformable Registration of Abdominal Mion-Enhanced MR Images for Presurgical and Radiotherapy
                                Planning of Lymph Nodes

Fred S. Azar¹, Christophe Chefdhotel¹, Ravi T. Seethamraju², Mukesh G. Harisinghani³

¹Siemens Corporate Research, Princeton, New Jersey, USA; ²Siemens Medical Solutions, Boston, Massachusetts, USA; ³Massachusetts General Hospital, Boston, Massachusetts, USA

                  1805.    MR Imaging of Bone Tumors - A Pictorial Review

Guenther K. Schneider¹, Peter M. Fries¹, Alexander Massmann¹, Dieter Kohn², Klaus Remberger¹, Roland M. Seidel³, Roland M. Seidel³

¹UniversityHospital of Saarland, Homburg, Saar, Germany; ²Saarland University Hospital, Homburg, Saar, Germany; ³Saarland UniversityHospital, Homburg, Saar, Germany