Brain: Miscellaneous MRS

                  2631.    ¹H MR Spectroscopic Assessment of Age-Related Changes in Young and Middle-Aged Women

Sarah Andrea Dunham¹, Kathleen L. Fuchs¹, Dattesh D. Shanbhag¹, Virginia I. Simnad¹, Jack Knight-Scott¹

¹University of Virginia, Charlottesville, Virginia, USA

                  2632.    Application of Proton MRSI to Assess Metabolic Status of the Brain in Post Traumatic
                                Brain Injury Depression

Mahaveer Degaonkar¹, Vani Rao¹, Jennifer Spiro¹, Alena Horska¹, Peter Barker¹

¹Johns Hopkins School of Medicine, Baltimore, Maryland, USA

                  2633.    Hierarchical Linear Modeling of Longitudinal Magnetic Resonance Spectroscopic Imaging

Ping-Hong Yeh¹, John Kornak², Hemanth Thayyullathil¹, Dieter Meyererhoff, ^1,2

¹Northern California Institute for Research and Education, San Francisco, California, USA;
²University of California, San Francisco, San Francisco, California, USA

                  2634.    A Novel Single-Voxel ¹H-MRS Sequence for Single-Shot Detection of Brain Glycine

Andrew Paul Prescot¹, Blaise deB Frederick¹, Marc J. Kaufman¹, Perry F. Renshaw¹

¹McLean Hospital, Belmont, Massachusetts, USA

                  2635.    Estimation of Myo-Inositol and Macromolecule Contents in Normal-Appearing White and
                                Gray Matter in MS Using 3D-HMRSI at 3T

Hélène Ratiney¹, Darin Okuda¹, Danielle Graveron-Demilly², Sarah J. Nelson¹, Steve Hauser¹, Daniel Pelletier¹

¹University of California, San Francisco, California, USA; ²Laboratoire de RMN, CNRS, UMR 5012,
Université LYON I-CPE, Lyon, France

                  2636.    Characterization of the Downfield Part of the Human Cerebral ¹H MR Spectrum at 3 T

Roland Kreis¹, Chris Boesch¹, Peter Vermathen¹

¹University Berne, Berne, Switzerland

                  2637.    Fast and High Resolution MRSI Without Aliasing Using Online SFAS and Multiple
                                Regions of Support

Yun Gao¹, Stephen M. Strakowski¹, Stanley J. Reeves², Hoby P. Hetherington³, Wenjang Chu¹, Jing-Huei Lee¹

¹University of Cincinnati College of Medicine, Cincinnati, Ohio, USA; ²Auburn University, Auburn, Alabama, USA;
³Albert Einstein College of Medicine, Bronx, New York, USA

                  2638.    Age-Related Changes in Brain Metabolites in Antiretroviral Medication-Stable HIV Patients

Kenneth Yue¹, Linda Chang¹, Daniel Alicata¹, Christine Cloak¹, Kathryn Taketa¹, Thomas Ernst¹

¹University of Hawaii, Honolulu, Hawaii, USA

                  2639.    Proton MR Spectroscopic Imaging in Neurofibromatosis Type-1: Relationship to
                                Neuropsychological Testing

Mona A. Mohamed¹, Jessica R. Abel², Sheryl L. Rimrodt², Laurie E. Cutting², Peter B. Barker¹, ²

¹Johns Hopkins University, Baltimore, Maryland, USA; ²Kennedy Krieger Institute, Baltimore, Maryland, USA

                  2640.    Effects of Smoking on Brain Metabolite Concentrations

Diana Marie Lindquist¹, Reid Landes¹, Kirstin Gatchalian¹, Richard Yi¹, Warren Bickel¹

¹University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

                  2641.    MRS Monitoring of the Effects of Mobile Phone Use on the Brain

Abdesslem Khiat¹, Guy Breton¹, Yvan Boulanger¹

¹Hôpital Saint-Luc du CHUM, Montreal, Quebec, Canada

                  2642.    Combined DWI and 1H-MRS Study of the Brain of Cirrhotic Patients

Caterina Tonon¹, Raffaele Lodi¹, Claudia Testa¹, Emil Malucelli¹, David Neil Manners¹, Bruno Barbiroli¹

¹Policlinico S.Orsola-Malpighi, Università di Bologna, Bologna, Italy, Italy

Brain MRI: The Next Frontier

                  2643.    Fast T1 Mapping of the Brain at 7T with RF Calibration Using Three Point DESPOT1 Method

Tie-Qiang Li¹, Sean C. L. Deoni²

¹NIH, Bethesda, Maryland, USA; ²King's College London, London, England, UK

                  2644.    Ultrahigh Field T2 in Human Brain: Regional Differences and Changes with Age

Petra Schmalbrock¹, Peter Wassennaar¹, Johannes T. Heverhagen¹, Truong-Kha Truong¹, Donald W. Chakeres¹,
Michael R. Thompson², John Duraj², Michael V. Knopp¹

¹The Ohio State University, Columbus, Ohio, USA; ²Philips, Cleveland, Ohio, USA

                  2645.    Improving Image Contrast in Conventional Dual Spin Echo at 3.0T with Short TE and
                                Flip Angle Optimization

Chen Lin¹, Mathew A. Bernstein¹, Krzysztof R. Gorny¹, John T. Wald¹, Robert J. Witte¹

¹Mayo Clinic College of Medicine, Rochester, Minnesota, USA

                  2646.    A New Technique for Phase Susceptibility-Weighted Imaging of Iron in the Brain

Melanie S. Kotys¹, David M. Thomasson¹, Nicholas Patronas¹

¹National Institutes of Health, Bethesda, Maryland, USA

                  2647.    Automatic Detection and Classification of Hypointensity in MR Images of the Brain

Radu Serban Jasinschi¹, Ahmet Ekin¹, Adriaan Cornelius van Es², Jeroen van der Grond²,

Mark Augustinus van Buchem², Arianne van Muiswinkel³

¹Philips Research, Eindhoven, Netherlands; ²Leiden University Medical Center, Leiden, Netherlands; ³Philips Medical Systems, Best, Netherlands

                  2648.    Time-Resolved Contrast Enhanced Neuro-Angiography Using HighlY Constrained Back
                                PRojection (HYPR) with a Hybrid Radial/Cartesian Acquisition (PR-TRICKS)

Yijing Wu¹, Patrick Turski¹, Yan Wu¹, Frank R. Korosec¹, Oliver Wieben¹, Jiang Du², Charies A. Mistretta¹

¹University of Wisconsin, Madison, Wisconsin, USA; ²University of California, San Diego, San Diego, California, USA

                  2649.    New Developments in Dynamic Time-Resolved Magnetic Resonance (MR)- Angiography
                                (TREAT) and High Resolution MR-Imaging of Cerebral Arterio-Venous Malformations (CAVM)
                                Using Parallel Imaging at 3T

Karin Anna Herrmann¹, Ulrike Fasol¹, Olaf Dietrich¹, Berndt Wowra², Alexander Muacevic², Maximilian F. Reiser¹, Stefan Oswald Schoenberg¹

¹Ludwig-Maximilians-University Hospitals Munich-Grosshadern, Munich, Bavaria, Germany;
²European Cyberknife Center Munich, Munich, Bavaria, Germany

                  2650.    Quantitative Aspects of Measuring Contrast Reagent Extravasation in the Healthy Human Brain

Xin Li¹, William Rooney¹, Charles Springer¹

¹Oregon Health & Science University, Portland, Oregon, USA

Dementia MRI/MRS

                  2651.    In Vivo Detection of Cerebral Glutathione in Aging and Alzheimer’s Disease Using Selective
                                Multiple Quantum Chemical Shift Imaging of GSH

In-Young Choi¹, ², John J. Sidtis², ³, Nunzio Pomara², ³, Sang-Pil Lee¹, ²

¹University of Kansas Medical Center, Kansas City, Kansas, USA; ²The Nathan Kline Institute, Orangeburg, New York, USA; ³New York University, New York, New York, USA

                  2652.    Validation Testing of the MRI Calibration Phantom for the Alzheimer's Disease
                                Neuroimaging Initiative Study

Jeff L. Gunter¹, Matt A. Bernstein¹, Bret J. Borowski¹, Joel P. Felmlee¹, Daniel James Blezek², Richard P. Mallozzi², Joshua R. Levy³,
Norbert Schuff⁴, Clifford R. Jack, Jr. ¹

¹Mayo Clinic and Foundation, Rochester, Minnesota, USA; ²GE Global Research, Niskayuna, New York, USA;
³The Phantom Laboratory, Salem, New York, USA; ⁴UC San Francisco, San Francisco, California, USA

                  2653.    Cortical Thickness Analysis in Mild Cognitive Impairment and Alzheimer’s Disease

Won-Jin Moon¹, Jong Min Lee², Eun Chul Chung¹

¹Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea;
²Hanyang University, Seoul, Republic of Korea

                  2654.    Regional Measurement of Hippocampal Atrophy in Alzheimer’s Disease Using Optimized
                                Manual ROI Segmentation and Voxel Based Morphometry

Rahyeong Juh¹, ², Min Ying Su¹, Chang Uk Lee², Tae Suk Suh², Orhan Nalcioglu¹

¹University of California, Irvine, California, USA; ²Catholic University of Korea, Seoul, Republic of Korea

                  2655.    Evidence for Elevated Brain Iron Concentration in Patients With

Anita Ramani¹, Kamila U. Szulc¹, Jens H. Jensen¹, Hanzhang Lu¹, Caixia Hu¹, Steven H. Ferris¹, Joseph A. Helpern¹

¹New York University School of Medicine, New York, New York, USA

                  2656.    Iron Deposition in the Putamen

Bharani Krishnamurthy¹, Ewart Mark Haacke¹, ², Muhammed Ayaz², Sheri Harder³, Daniel Kido⁴, Wolff Kirsch⁴

¹Wayne State University, Detroit, Michigan, USA; ²The MRI Institute for Biomedical Research, Detroit, Michigan, USA;
³University of Saskatchewan, Saskatoon, Saskatchewan, Canada; ⁴Loma Linda University, Loma Linda, California, USA

                  2657.    Using SWI as a Means to Better Visualize the Caudate Nucleus in Huntington’s Disease

Mark E. Haacke¹, Lakshman Gollapalli¹, Diana H. Rosas², Ken Kwong²

¹Wayne State University, Detroit, Michigan, USA; ²Massachusetts Institute of Technology, Boston, Massachusetts, USA

                  2658.    Magnetic Resonance Diffusion and Spectroscopy Abnormalities in Different Forms of
                                Creutzfeldt-Jakob Disease

Danielle Ibarrola¹, Marc Hermier², Alain Vighetto², Pierre Krolak-Salmon², Jean-Claude Froment²,

Dominique Sappey-Marinier¹, ³

¹IFR19, CERMEP - Imagerie du vivant, Bron, France; ²Hôpital Neurologique, Bron, France;
³CREATIS CNRS UMR5515 & INSERM U630 - Université Claude Bernard, Lyon, France

                  2659.    Quantitative Magnetic Resonance and Histological Analysis of Primary Motor Neuronal Loss
                                in Amyotrophic Lateral Sclerosis

Mark David Meadowcroft¹, James R. Connor², Zachary Simmons¹, Don C. Bigler¹, Jian-Li Wang¹, Michael B. Smith¹, Qing X. Yang²

¹Pennsylvania State University - College of Medicine, Hershey, Pennsylvania, USA; ²Pennsylvania State University -  College of Medicine, Hershey, Pennsylvania, USA

Brain: Magnetization Transfer

                  2660.    WIMP: Self-Navigating Magnetization Transfer Pool Mapping with Stimulated Echoes

Rexford Newbould¹, Chunlei Liu¹, Stefan Ropele², Roland Bammer¹

¹Stanford University, Stanford, California, USA; ²Medical University Graz, Graz, Austria

                  2661.    A Measurement of the  Magnetization Exchange Between the Different Water
                                Compartments in Optic Nerve

Hadassah Shinar¹, Uzi Eliav¹, Gil Navon¹

¹Tel Aviv University, Tel Aviv, Israel

                  2662.    Describing Magnetization Transfer Parameters in White Matter Using a Four-Pool Model

Thorarin Albert Bjarnason¹, Alex L. MacKay²

¹University of Calgary, Calgary, AB, Canada; ²University of British Columbia, Vancouver, BC, Canada

                  2663.    Correlation of Magnetization Transfer Ratio with Cognitive Impairment in HIV

Ying Wu¹, Pippa Storey¹, Andres Carrillo², Leon G. Epstein³, Bruce Cohen³, Robert R. Edelman¹, Ann Ragin³

¹Evanston Northwestern Healthcare, Feinberg School of Medicine, Northwestern University, Evanston, Illinois, USA;
²GE Medical Healthcare, Evanston, Illinois, USA; ³Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA

                  2664.    Regional MRI Measures and Disability in Multiple Sclerosis

Robert Zivadinov¹, Ralph HB Benedict¹, Bhooma Srinivasaraghavan¹, Dominic Carone¹, Viritha Yella¹,

Nadir Abdelrahman¹, Michael G. Dwyer¹

¹Buffalo Neuroimaging Analysis Center, Buffalo, New York, USA

                  2665.    Intercentre Differences in Multicentre Brain MTR Histogram Studies Can Almost Be
                                Eliminated by Using Body Coil Transmission

Paul S. Tofts¹, Stefan CA Steens², Mara Cercignani¹, Daniel J. Tozer¹, Wouter M. Teeuwisse², Matthijs JP van Osch²,
 Faiza Admiraal-Behloul², Gareth J. Barker³, Mark A. van Buchem²

¹University College London, London, UK; ²LUMC, Leiden, Netherlands; ³KCL, London, UK

                  2666.    Fast Magnetization Transfer Imaging, a Comparative Study

Wouter Teeuwisse¹, Matthias van Osch¹, Hans Olofsen¹, Bart Emmer¹, Jeroen van der Grond¹

¹Leiden University Medical Center, Leiden, Netherlands

                  2667.    Diffusion Tensor and Magnetization Transfer Imaging of the Brain at 3T in
                                Patients with Cirrhosis

Vijay Paul Bob Grover¹, Serena J. Counsell¹, Nayna Patel¹, Joanna M. Allsop¹, Elizabeth J. Bradford²,

Brian K. Saxby², Joseph V. Hajnal¹, Simon David Taylor-Robinson¹

¹Hammersmith Hospital, Imperial College London, London, UK; ²Cognitive Drug Research, Goring-on-Thames, UK

                  2668.    Longitudinal MTR Changes in Mild to Severe Alzheimer’s Disease

Stefan Ropele¹, Faton Gorani¹, Christian Enzinger¹, Birgit Pendl¹, Alexandra Seewann¹, Reinhold Schmidt¹,

Franz Fazekas¹

¹Medical University Graz, Graz, Austria

                  2669.    Magnetization Transfer Imaging in Distinguishing Early and Adult Onset Schizophrenia
                                in Drug-Naive First-Episode Patients

Xiaoqi Huang¹, Yuqing Wang², Su Lui¹, Wei Deng¹, Luo Ouyang², Hehan Tang¹, Tao Li¹, Bin Song¹, Xiangping Zhou¹, Sumner Maclean³, Vanessa Sluming⁴, Qiyong Gong¹

¹West China Hospital of Sichuan University, Chengdu, Sichuan, People’s Republic of China; ²University of Electronic Science and Technology of China, Chengdu, Sichuan, People’s Republic of China; ³Universitatsklinikum, Goettingen, Germany; ⁴University of Liverpool, Liverpool, UK

                  2670.    Correlative Analysis of Anisotropy Diffusion Coefficient and Magnetization Transfer Ratio
                                with Serum Antibody Brain Binding and Antiphospholipid Antibodies in Multiple Sclerosis

Mehdi Adineh¹, ², Michael Kent¹, ², Ninad Mantri¹, Navin Kausthubh¹, Cemil Kirbas¹, Sehul Shah¹, Kenneth Pugar¹

¹The Wallace Kettering Neuroscience Institute, Kettering, Ohio, USA; ²Wright State University, Dayton, Ohio, USA

Stroke

                  2671.    Moyamoya Disease: Visualization of Dilated Medullary Vessels by Flow-Compensated
                                Gadolinium-Enhanced MRI

Eri Kitamura¹, ², Mitsunori Kanagaki², Yukio Miki², Akira Yamamoto², Yasutaka Fushimi², Tsutomu Okada²,

Nobuyuki Mori², Ken-ichiro Kikuta², Susumu Miyamoto², Nobuo Hashimoto², Kazuro Sugimura¹, Kaori Togashi²

¹Kobe University Graduate School of Medicine, Kobe, Japan; ²Kyoto University Graduate School of Medicine, Kyoto, Japan

                  2672.    The Feasibility of a Spin-Echo EPI Based Perfusion MRI in Moyamoya Disease on a 3.0T MR System

In-Chan Song¹, Jung-Eun Cheon¹, In-One Kim¹, Kee-Hyun Chang¹, Dong-Gyu Na¹

¹Seoul National University Hospital, Seoul, Republic of Korea

                  2673.    Cerebral Blood Flow Velocity and White Matter Changes in Type 2 Diabetes Mellitus

David Last¹, David C. Alsop¹, Amir M. Abduljalil², Kun Hu¹, Jerry Cavallerano³, Lukas Lepicovsky¹,

Christopher Robles¹, Lewis A. Lipsitz¹, ⁴, Vera Novak¹

¹Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA; ²College of Medicine and Public Health, Ohio State University, Columbus, Ohio, USA; ³Joslin Diabetes Center, Boston, Massachusetts, USA; ⁴Hebrew Seniorlife Center, Boston, Massachusetts, USA

                  2674.    Cerebral Developmental Venous Anomalies Associated with Loco-Regional Parenchymal
                                Abnormalities

Francesca B. Pizzini¹, Diego San Millán Ruíz², Enrico Piovan¹, Alberto Beltramello¹, Daniel Rüfenacht³

¹University Hospital Verona, Verona, Italy, Italy; ²Geneva University Hospital, Geneva, Switzerland, Switzerland; ³Geneva University Hospital, Geneve, Switzerland, Switzerland

                  2675.    In Vivo Human Middle Cerebral Artery Wall Imaging Using High Resolution
                                Magnetic Resonance Imaging

Isabelle Klein¹, Philippa Lavallée¹, Pierre-Jean Touboul¹, Elisabeth Schouman-Claeys¹, Pierre Amarenco¹

¹Medical Hospital and University of Bichat, Paris, France

                  2676.    The Relationship Between the Carotid Atherosclerotic Plaque and Cerebral
                                Perfusion-Weighted Imaging: Preliminary Results

Xin Lou¹, Ning Yu An¹, Jian Min Cai¹, Lin Ma¹, Xue Mei Li¹, Wei Sun²

¹PLA General Hospital, Beijing, People’s Republic of China; ²GE Healthcare, Beijing, People’s Republic of China

                  2677.    The Composition of Acute MCA Thrombus is Heterogeneous: A Comparison of
                                MR Susceptibility Image and CTA

Mingwang Zhu¹, Masahiko Hiroki¹, Hakan Ay¹, Aneesh B. Singhal¹, Nina M. Menezes¹, Chloe Joan Lopez¹, Christopher Melinosky¹,
A Gregory Sorensen¹

¹Massachusetts General Hospital, Charlestown, Massachusetts, USA

                  2678.    3 T Vs 1.5 T MR Diffusion and Perfusion Imaging in Hyper-Acute Ischemic Stroke

Robert Karl Kosior¹, ², Michael D. Hill¹, ³, Jayme Cameron Kosior¹, ², Richard Frayne¹, ²

¹University of Calgary, Calgary, Alberta, Canada; ²Foothills Medical Centre, Calgary Health Region, Calgary, Alberta, Canada;
³Foothills Medical Centre, Calgary, Alberta, Canada

                  2679.    Artifact Simulating Subarachnoid and Intraventricular Hemorrhage on Single Shot Fast Spin Echo
                                Flair Images: A Trap for the Unwary

Alessandro Cianfoni¹, Maria GM Martin¹, Jiang Du¹, John R. Hesselink¹, Steven G. Imbesi¹, William G. Bradley¹, Graeme M. Bydder¹

¹University of California, San Diego, San Diego, California, USA

                  2680.    A New Approach Using the Distribution of Transit Times (DTT) to Determine Improved Absolute
                                CBF Values in Patients with Ischemic Stroke

Marina Salluzzi¹, Richard Frayne², ³, Michael R. Smith¹, ³

¹Electrical and Computer Engineering, University of Calgary, Calgary, Alberta, Canada;
²Seaman Family MR Research Centre, Foothills Medical Centre, Calgary, Alberta, Canada;
³Radiology, University of Calgary, Calgary, Alberta, Canada

                  2681.    Pediatric and Adult Global Hypoxic-Ischemic Injury Evaluated by Diffusion-Weighted
                                Imaging and MR Spectroscopy

Karen Angela Tong¹, Anna Dengel¹, Carrie Carr¹, Udo Oyoyo¹, Stephen Ashwal¹, Sarah Uffindell¹,

Barbara Ann Holshouser¹

¹Loma Linda University Medical Center, Loma Linda, California, USA

                  2682.    Altered BOLD Hemodynamic Response in Patients with Ischemic Stroke

Kaundinya Gopinath¹, Anna Moore², Kyung Peck³, Bruce Crosson⁴, ⁵, Richard Briggs¹

¹UT Southwestern, Dallas, Texas, USA; ²Emory University, Atlanta, Georgia, USA;
³Memorial Sloan Kettering Cancer Center, New York, New York, USA; ⁴University of Florida, Gainesville, Florida, USA;
⁵VA Medical Center, Gainesville, Florida, USA

                  2683.    Visualization of Collateral Supply by Two-Coil Continuous Arterial Spin Labeling

Harald E. Möller¹, ², Toralf Mildner¹, Christoph Preul¹, Claus Zimmer³

¹Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; ²University Hospital Münster, Münster, Germany;
³University Hospital Leipzig, Leipzig, Germany

Methods in Arterial Spin Labeling

                  2684.    Toward Quantitative Whole Brain Pulsed Arterial Spin Labeling: Estimation of
                                Transit Time with Cardiac Gating at 3T

Wen-Ming Luh¹, Jerzy Bodurka¹, Peter A. Bandettini¹

¹National Institutes of Health, Bethesda, Maryland, USA

                  2685.    Dynamic Relationship Between Arterial Transit Time and Perfusion and Its Implications
                                for Fast ASL Quantification

Gregory R. Lee¹, Luis Hernandez-Garcia¹, Vikas Gulani¹, Douglas Noll¹

¹University of Michigan, Ann Arbor, Michigan, USA

                  2686.    Mapping of Arterial Transit Time Using Dual-Coil CASL with Sinusoidally Modulated Labeling Function

Toralf Mildner¹, Karsten Müller¹, Stefan Hetzer¹, Robert Trampel², Wolfgang Driesel¹, Harald E. Möller¹, ³

¹Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Saxony, Germany;
²NYU School of Medicine, New York, New York, USA; ³University Hospital Münster, Münster, NRW, Germany

                  2687.    Estimation of Blood Magnetization for Quantification of Arterial Spin Labeling Signal

Kim Cornelia Carolina van de Ven¹, ², Esben Thade Petersen¹, ³, Xavier Golay¹, ⁴

¹National Neuroscience Institute, Singapore, Singapore; ²Eindhoven University of Technology, Eindhoven, Netherlands;
³Nanyang Technological University, Singapore, Singapore; ⁴A*star, Singapore, Singapore

                  2688.    Combined Blood:Brain Partition Coefficient and Perfusion Assessment Using QUASAR

Esben Thade Petersen¹, Kim Cornelia Carolina van de Ven¹, ², Ivan Zimine¹, Xavier Golay, ¹³

¹National Neuroscience Institute, Singapore, Singapore; ²Eindhoven University of Technology, Eindhoven, Netherlands;
³ASTAR, Singapore, Singapore

                  2689.    The Effect of Fat Saturation on Arterial Spin Labeling

Yufen Chen¹, Todd B. Parrish¹

¹Northwestern University, Chicago, Illinois, USA

                  2690.    Sub-Minute Arterial Spin Labelling at 3.0T

Elizabeth A. Moore¹, Frank G. C. Hoogenraad², Xavier Golay³, ⁴, Ebsen Thade Petersen³, Maarten Versluis²,

J M. den Harder², Ad Moerland²

¹Philips Medical Systems UK, Reigate, UK; ²Philips Medical Systems, Best, Netherlands;
³National Neuroscience Institute, Singapore, Singapore; ⁴Singapore Bioimaging Consortium, Singapore, Singapore

                  2691.    In-Vivo Measurement of Arterial Cerebral Blood Volume Using LL-EPI-FAIR
                                and LL-EPI-STAR

Matthew Jon Brookes¹, Peter G. Morris¹, Penny A. Gowland¹, Susan T. Francis¹

¹University of Nottingham, Nottingham, UK

                  2692.    Activation Induced Changes in Arterial Cerebral Blood Volume (ACBV)
                                Measured Using LL-EPI-STAR

Matthew Jon Brookes¹, Peter G. Morris¹, Penny A. Gowland¹, Susan T. Francis¹

¹University of Nottingham, Nottingham, UK

                  2693.    Reducing Contamination in PASL Using BASSI RF Pulses

Jan M. Warnking¹, G. Bruce Pike¹

¹Montreal Neurological Institute, McGill University, Montreal, Québec, Canada

                  2694.    Pseudo Random Amplitude Modulation: A High Efficiency Method to Measure Flow
                                and Perfusion

Truman R. Brown¹, Nina C. Shapley¹, Haiying Tang²

¹Columbia University, New York, New York, USA; ²Merck Research Laboratories, Rahway, New Jersey, USA

                  2695.    Sensitivity and Detectability of Regional Differences in CASL Perfusion
                                Between Subject Groups

Ruth L. O'Gorman¹, ², Steven C. Williams², David C. Alsop³, Fernando O. Zelaya²

¹King's College Hospital, London, UK; ²Institute of Psychiatry, London, UK; ³Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

                  2696.    Quantitative Cerebral Vascular Response Maps: Determination with Pulsed Arterial Spin Labelling

Ulrike Noeth¹, ², Futoshi Kotajima³, Ralf Deichmann², Robert Turner², Douglas R. Corfield³, ⁴

¹GSF Forschungszentrum fuer  Umwelt und Gesundheit, Neuherberg, Germany;
²Institute of Neurology, UCL, London, UK; ³National Heart & Lung Institute, Imperial College, London, UK; ⁴Keele University, Keele, UK

Ronald L. Wolf¹, Jiongjiong Wang¹, John A. Detre¹, Eric L. Zager¹, Robert W. Hurst¹

¹University of Pennsylvania Medical Center, Philadelphia, Pennsylvania, USA

                  2698.    Regional Effects of Type 2 Diabetes Mellitus on Cerebral Blood Flow and Brain Anatomy
                                    Using MRI and Continuous Arterial Spin Labeling MRI at 3 Tesla

David Last¹, David C. Alsop¹, Amir M. Abduljalil², Robert P. Marquis¹, Christopher Robles¹, Vera Novak¹

¹Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA; ²College of Medicine and Public Health, Ohio State University, Columbus, Ohio, US

                  2699.    Assessment of Hypertension on Cerebral Blood Flow and Dementia Using CASL MRI

Weiying Dai¹, Owen T. Carmichael, ^1,2, Oscar L. Lopez¹, James T. Becker¹, Lewis H. Kuller¹, H. Michael Gach, ¹³

¹University of Pittsburgh, Pittsburgh, Pennsylvania, USA; ²Carnegie Mellon University, Pittsburgh, Pennsylvania, USA; ³Nevada Cancer Institute, Las Vegas, Nevada, USA

                  2700.    Close Correlation of ASL MRI and Ultrasound Derived Intracranial Blood Flow Velocities

Martin Griebe¹, Kristina Szabo¹, Matthias Günther¹, Rolf Rüdiger Kern¹, Fabrizio Sallustio¹, Michael G. Hennerici¹, Achim Gass¹, ²

¹Universitätsklinikum Mannheim, Mannheim, Germany; ²Universitätsspital Basel, Basel, Switzerland

DWI/DTI : Clinical Applications

                  2701.    Functional Connectivity Correlations in the Cortical-Thalamic Network of Patients with
                                Schizophrenia Using fMRI and DTI

David Matthew Carpenter¹, Gustavo Pantol¹, Joeseph I. Friedman¹, Cheuk Y. Tang¹

¹Mount Sinai School of Medicine, New York, New York, USA

                  2702.    Quantitative Analyses of  Dentate Nuclei and Cerebellar Peduncles Based on DTI in
                                    Langerhans Cell Histiocytosis

Weihong Zhang¹, ², Jiangyang Zhang¹, ², Hao Huang¹, ², Peter C.M. van Zijl¹, ², Robert J. Arceci¹, Susumu Mori¹, ²

¹Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA; ²Kennedy Krieger Institute, Baltimore, Maryland, USA

                  2703.    A Preliminary Result of Principal Diffusion Direction Comparison in
                                Attention-Deficit/Hyperactivity Disorder

Tzu-Cheng Chao¹, Hsiao-Wen Chung¹, Pin-Chen Yang², Ming-Ting Wu³, ⁴

¹National Taiwan University, Taipei, Taiwan; ²Kaohsiung Medical University, Kaohsiung, Taiwan;

³Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; ⁴National Yang Ming University, Taipei, Taiwan

                  2704.    A Diffusion-Tensor MRI Study of Brain and Cervical Cord in Benign Multiple
                                Sclerosis Patients

Beatrice Benedetti¹, Paola Valsasina¹, Elda Judica¹, Vittorio Martinelli¹, Angelo Ghezzi², Annalisa Pulizzi¹,

Giancarlo Comi¹, Massimo Filippi¹

¹Hospital San Raffaele, Milan, Italy, Italy; ²Ospedale di Gallarate, Gallarate, Italy, Italy

                  2705.    Diffusion Weighted Imaging Study of Patients with Essential Tremor

R Lodi¹, G Rizzo¹, D Manners¹, C Tonon¹, C Scaglione¹, P Martinelli¹, B Barbiroli¹

¹Università di Bologna, Bologna, Italy, Italy

                  2706.    Differentiating Perihemorrhagic Infarct from Susceptibility Artifact on DWI Images

Scott K. Nagle¹, David B. Clayton¹, Maarten G. Lansberg¹, Gregory W. Albers¹, Roland Bammer¹

¹Stanford University, Stanford, California, USA

                  2707.    Diffusion Tensor Imaging in Differentiation of PLS Patients and Healthy Controls

Liang Xuan¹, Peter A. Hardy¹, David K. Powell¹, Anders Andersen¹, Don M. Gash¹, Charles Smith¹

¹University of Kentucky, Lexington, Kentucky, USA

                  2708.    Mapping Radiation Dose Distribution on the Fractional Anisotropy Map: Applications
                                in the Assessment of Treatment-Induced White Matter Injury

Deqiang Qiu¹, Lucullus Leung¹, Dora Kwong¹, Godfrey Chan¹, Guang Cao², Pek-Lan Khong¹

¹The University of Hong Kong, Hong Kong, People’s Republic of China; ²GE Medical, Asia, Hong Kong, People’s Republic of China

                  2709.    Variability in ADC and FA Measurements in Acute Ischemic Stroke

Mirthula Govindaraj¹, Ashley D. Harris, ^1,2, Richard Frayne²

¹Foothills Medical Centre, Calgary Health Region, Calgary, Alberta, Canada; ²University of Calgary, Calgary, Alberta, Canada

                  2710.    In Vivo Brain 1H-MRS and DWI, and Post-Mortem Study of Patients with Mitochondrial
                                Neurogastrointestinal Encephalomyopathy (MNGIE)

Caterina Tonon¹, David Neil Manners¹, Piero Parchi², Roberto De Giorgio¹, Carlo Casali³, Maria Lucia Valentino², ⁴, Michio Hirano⁵,
Giuseppe Plazzi², Marzio Bellan, Valerio Carelli, Bruno Barbiroli¹, Raffaele Lodi¹

¹Policlinico S'Orsola-Malpighi, Università di Bologna, Bologna, Italy, Italy; ²Università di  Bologna, Bologna, Italy, Italy;
³Università “La Sapienza”, IRCCS Mondino-SanRaffaele Pisana, Roma, Italy, Italy; ⁴Columbia University, New York  City, New York, USA;
⁵Columbia University, New York City, New York, USA

                  2711.    Investigation of the Effects of Concurrent Chronic Cigarette Smoking in Alcoholics–
                                a Preliminary Diffusion Tensor Imaging Study

Stefan Gazdzinski¹, Timothy C. Durazzo¹, Ping-Hong Yeh¹, ², Geon-Ho Jahng², Pratik Mukherjee², Dieter J.

Meyerhoff, ^1,2

¹NCIRE, San Francisco, California, USA; ²UCSF, San Francisco, California, USA

                  2712.    Whole Brain FA Histogram Analysis for Improved Detection of DAI

Shashwath Ashok Meda¹, Koushik Athreya Govindarajan¹, Malek Makki¹, Robin Hanks², Jay Meythaler², Scott Mills², Zahid Latif¹,
 William Coplin³, Ewart Mark Haacke¹, Randall Reed Benson², ⁴

¹Wayne State University, Detroit, Michigan, USA; ²Wayne State University School of Medicine, Detroit, Michigan, USA;
³Detroit Receiving Hospital, Detroit, Michigan, USA; ⁴Detroit Medical Center, Detroit, Michigan, USA

                  2713.    Quantitative Evaluation of the White Matter Tracts of the Limbic System Segmented
                                by Diffusion Tensor Tractography: Feasibility Study of the Patients with Schizophrenia

Haruyasu Yamada¹, Shigeki Aoki¹, Hidenori Yamasue¹, Kiyoto Kasai¹, Osamu Abe¹, Mariko Yoshida²,

Yoshitaka Masutani¹, Harushi Mori¹, Tomohiko Masumoto¹, Naoto Hayashi¹, Toshiyuki Okubo¹, Kuni Ohtomo¹

¹Graduate School of Medicine, University of Tokyo, Tokyo, Japan; ²School of Medicine,
Kanazawa University, Kanazawa, Ishikawa, Japan

                  2714.    Atrophy and Diffusion Tensor MRI Metrics of Brain Fiber Bundles. Application to Primary
                                Progressive Multiple Sclerosis Patients

Elisabetta Pagani¹, Beatrice Benedetti¹, Elda Judica¹, Marco Rovaris¹, Giancarlo Comi¹, Massimo Filippi¹

¹Scientific Institute and University Ospedale San Raffaele, Milan, Italy

                  2715.    DTI of the Optic Nerve

Ashok Kumar¹, Andre J.W. Van-Der-Kouwe¹, Alma Gregory Sorensen¹, Paul Caruso²

¹Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA; ²Massachusetts Eye & Ear Infirmary,
Boston, Massachusetts, USA

The Normal Brain: DWI/DTI Analysis

                  2716.    A Refined DTI Study Shows Increased Sensitivity on an MTBI Study: Results
                                Highly Correlated with Proteomic Findings

Tong Zhu¹, Jeffrey J. Bazarian¹, Jianhui Zhong¹

¹University of Rochester, Rochester, New York, USA

                  2717.    Age-Related Changes Analyzed Using Whole-Brain Tissue Histogram: A DTI Study of
                                Two Different B Values

Elin Lundström¹, Per Julin², Lars-Olof Wahlund³, Leif Svensson¹, Kelvin Lim⁴, Eva-Lena Engman¹, Lars Bäckman³, Laura Fratiglioni³,
Anders Frank¹

¹Karolinska University Hospital Huddinge, Stockholm, Sweden; ²Astra Zeneca, Södertälje, Sweden; ³Karolinska Institutet, Stockholm, Sweden;
⁴University of Minnesota, Minneapolis, Minnesota, USA

                  2718.    Myelination and Axonal Integrity of Spinal Cord Sensory and Motor Pathways
                                Revealed by Diffusion Tensor MRI

Craig K. Jones¹, ², Seth A. Smith¹, ², John W. McDonald¹, Jonathan A. Farrell¹, ², Peter Calabresi³, Susumu Mori¹, ², Peter C.M. van Zijl¹, ²

¹Kennedy Krieger Institute, Baltimore, Maryland, USA; ²Johns Hopkins University School of Medicine, Baltimore, Maryland, USA;
³Johns Hopkins Medical Institutes, Baltimore, Maryland, USA

                  2719.    Fractional Anisotropy as a Tool for Characterization of White Matter Fiber Tract Integrity in the
                                Aging Rhesus Monkey Brain

Alexandre Coimbra¹, Marie A. Holahan¹, Yevgen Tymofyeyev¹, Richard Hargreaves¹, Jacquelynn J. Cook¹,

Donald S. Williams¹

¹Merck Research Laboratories, West Point, Pennsylvania, USA

                  2720.    Diffusion Tensor MR Imaging: Analysis of Anisotropy Metrics in the Aging Brain

Yi-Jui Liu¹, Chun-Jung Juan², ³, Cheng-Hsien Hsu¹, Ming-Chung Chou², Teng-Yi Huang⁴, Hsiao-Wen Chung²,

Cheng-Yu Chen³

¹Feng-Chia University, Taichung, Taiwan; ²National Taiwan University, Taipei, Taiwan;
³Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan;
⁴National Taiwan University of Science and Technology, Taipei, Taiwan

                  2721.    Mapping Dynamic Water Diffusion Process Inside Human Brain Based on
                                Numerical Solution of the Diffusion Equation

Wang Zhan¹, Li Jiang², Yihong Yang¹

¹National Institute on Drug Abuse, NIH, Baltimore, Maryland, USA; ²George Washington University,
Washington, District of Columbia, USA

                  2722.    Correlations Between Diffusion Tensor Indices and Intravoxel Tissue
                                Volume Fractions in Human Brain

Wang Zhan¹, Hong Gu¹, Elliot A. Stein¹, Yihong Yang¹

¹National Institute on Drug Abuse, NIH, Baltimore, Maryland, USA

                  2723.    Validation of Diffusion Tensor Imaging

D. Reamer¹, Fick T. Shush¹, F.H. Fool and Hardy¹

¹Institute of Dreams and Imaginings of Trendy Science, Buggtussle, California, USA

Resolving Multiple Fibers and Novel Approaches to DWI Analysis

                  2724.    The Effects of Intra-Voxel Fiber Architecture on the Diffusion Tensor  Parameters

Ryan Fobel¹, Greg J. Stanisz²

¹University of Toronto, Toronto, ON, Canada; ²Sunnybrook & Womens' CHSC, Toronto, ON, Canada

                  2725.    Dependence of the DTI Signal on the Presence of Fiber Crossing

Nicolas Kunz¹, Rolf Gruetter¹

¹Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

                  2726.    Linear Persistent Angular Structure MRI and Non-Linear Spherical Deconvolution for Diffusion MRI

Kiran Kumar Seunarine¹, Daniel C. Alexander¹

¹University College London, London, UK

                  2727.    Application of Independent Component Analysis for Resolving Multiple Fibre Orientations in DT-MRI Data

Laurence Vigon¹, Nikos Papadakis¹

¹The University of Sheffield, Sheffield, UK

                  2728.    Resolve Fiber Orientation Ambiguity Using HARD Imaging

Xin Hong¹, Adam W. Anderson¹, Zhaohua Ding¹

¹Vanderbilt University, Nashville, Tennessee, USA

                  2729.    Quantitative Analysis of Q-Space MRI Data: Theoretical and Experimental Validation

L Guy Raguin¹, Diego Hernando¹, Dimitris Karampinos¹, Luisa Ciobanu¹, Brad P. Sutton¹, Zhi-Pei Liang¹,

John G. Georgiadis¹

¹University of Illnois at Urbana-Champaign, Urbana, Illinois, USA

                  2730.    Bootstrap Tractography Using Multimodal Fiber Orientation Data from High Angular Resolution
                                Diffusion Imaging

Jeffrey I. Berman¹, Pratik Mukherjee¹, Christopher P. Hess¹, Eric T. Han², SungWon Chung¹, Roland G. Henry¹

¹University of California San Francisco, San Francisco, California, USA; ²GE Healthcare Global Applied Science Laboratory, Menlo Park, California, USA

                  2731.    Regularized Diffusion Tensor MRI for High Angular Resolution ODF Estimation and Fibre
                                Tractography

Jennifer S.W. Campbell¹, ², Peter Savadjiev², G. Bruce Pike¹, Kaleem Siddiqi²

¹Montreal Neurological Institute, Montreal, Quebec, Canada; ²McGill Centre for Intelligent Machines, Montreal, Quebec, Canada

                  2732.    Two Tensor Analysis for White Matter Tractography - Methodological Evaluation

Sharon Peled¹, Carl-Fredrik Westin¹

¹Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA

                  2733.    Brain Segmentation Using ATP (Automatic Twice PAM) in Multi Diffusion Indices

Yi-Ping Chao¹, Kuan-Huang Cho¹, Chun-Hung Yeh², Sue-Ping Tsao², Der-Yow Chen¹, Jyh-Horng Chen¹,

Ching-Po Lin²

¹Institute of Electrical Engineering, National Taiwan University, Taipei, Taiwan; ²National Yang-Ming University, Taipei, Taiwan

                  2734.    Time-Series' Analysis of the Diffusion Weighted Signal as a Model-Free Approach to Segmenting
                                Tissue

Sean CL Deoni¹, Derek K. Jones¹

¹Institute of Psychiatry, King's College, London, England, UK

                  2735.    Method of Measuring Diffusion Anisotropy and Diffusion Gradient Simultaneously with DTI

Jie Huang¹

¹Michigan State University, East Lansing, Michigan, USA

                  2736.    From DTI to CTI: The Role of Anisotropic Conductivity of the White Matter Tissue – an EEG FEM
                                Simulation Study

Daniel Güllmar¹, Jürgen R. Reichenbach¹, Alfred Anwander², Carsten H. Wolters³, Jens Haueisen¹, ⁴

¹Friedrich-Schiller-University, Jena, Germany; ²Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany;
³Westfalian Wilhelms-University Muenster, Münster, Germany; ⁴Technical University Ilmenau, Ilmenau, Germany

Fiber Tracking and Visualization

                  2737.    Current State of Diffusion Simulation Based Tractography

Sarah Mang¹, Ning Kang², Jun Zhang², Eric S. Carlson³, Daniel Gembris¹, Reinhard Männer¹

¹University of Mannheim, Mannheim, Germany; ²University of Kentucky, Lexington, Kentucky, USA; ³University of Alabama, Tuscaloosa, Alabama, USA

                  2738.    Anisotropic Fiber Phantom for DTI Validation on a Clinical Scanner

Ramona Lorenz¹, ², Björn W. Kreher¹, Jürgen Hennig¹, Matthias E. Bellemann², Kamil A. Il'yasov¹

¹University Hospital Freiburg, Freiburg, Germany; ²University of Applied Sciences Jena, Jena, Germany

                  2739.    Quantitative Validation of White Matter Fiber Tractography by Use of an Anatomically
                                Realistic Synthetic Diffusion Tensor Phantom

Steven Delputte¹, Els Fieremans¹, Yves Dedeene², Yves D'Asseler¹, Rik Achten², Ignace Lemahieu¹, Rik Van de Walle¹

¹Ghent University, Ghent, Belgium; ²Ghent University Hospital, Ghent, Belgium

                  2740.    Validation of Multi-Fibre Probabilistic Tractography of Corticothalamic Projections in the
                                Göttingen Minipig Brain

Tim Bjørn Dyrby¹, Lise S L Vejby¹, Geoffery J. M. Parker², Daniel C. Alexander³, Nanna M. Lind⁴, Olaf B. Paulson¹, Jacob Jelsing⁵

¹Copenhagen University Hospital, Hvidovre, Denmark; ²University of Manchester, Manchester, UK; ³University College London, London, UK;
⁴University of Copenhagen, Copenhagen, Denmark; ⁵Bispebjerg University Hospital, Copenhagen, Denmark

                  2741.    A Comparison of Fiber Tracking by Different Numerical Integration Methods

RKS Rathore¹, Getaneh Bayu¹, RK Gupta², Divya KS Rathore¹, Ankur Purwar¹, Richa Trivedi², Sona Saksena²,

Manoj Kumar Sarma¹, Anup Singh¹

¹Indian Institute of Technology, Kanpur, UP, India; ²Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, UP, India

                  2742.    Automated Assessment of Tract Similarity in Group Diffusion MRI Data

Jonathan D. Clayden¹, Mark E. Bastin¹, Amos J. Storkey¹

¹University of Edinburgh, Edinburgh, UK

                  2743.    Tract-Specific Mapping of Diffusion Anisotropy Index

Li-Wei Kuo¹, Van Jay Wedeen², Jui-Chang Tsai³, Ham-Min Tseng³, Jun-Cheng Weng¹, Su-Chun Huang⁴,

Timothy G. Reese², Jyh-Horng Chen¹, Wen-Yih Isaac Tseng, ³⁴

¹National Taiwan University, Taipei, Taiwan; ²Harvard Medical School, Charlestown, Massachusetts, USA;
³National Taiwan University Hospital, Taipei, Taiwan; ⁴National Taiwan University College of Medicine, Taipei, Taiwan

                  2744.    Visualization of Absolute T1 and T2 Along Specific White Matter Tracts

Derek K. Jones¹, Sean CL Deoni¹

¹Institute of Psychiatry, London, UK

                  2745.    Fiber Tract Based Interrogation of White Matter

Jeffrey Thomas Duda¹, Hui Zhang¹, Tony J. Simon², James C. Gee¹

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA; ²University of California, Davis, Davis, California, USA

                  2746.    Interactive Digital Stereotaxic White Matter Atlas in Talairach Coordinates (SWAT)

Hangyi Jiang¹, ², Jiangyang Zhang¹, Peter C.M. van Zijl¹, ², Susumu Mori¹, ²

¹Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; ²Kennedy Krieger Institute, Baltimore, Maryland, USA

                  2747.    High Spatial Resolution Probabilistic DT Fibre Tracking Using Seeding Points from
                                fMRI Statistical Parameter Maps

Goran Vucurevic¹

¹University Hospital Mainz, Mainz, Germany

                  2748.    Connectivity-Based Parcellation of the Midsagittal Corpus Callosum in Human Brain Using
                                Diffusion Probability Tractography

Ruiwang Huang¹, Oleg Posnansky¹, Lars Hoemke¹, Katrin Amunts¹, NJ Jon Shah¹

¹Research Centre Juelich, Juelich, Germany

                  2749.    On the Thresholding of Probabilistic Fibre Tracking Maps

Hubert Fonteijn¹, ², David G. Norris², Frans Verstraten¹

¹Helmholtz Institute, Utrecht, Netherlands; ²F.C. Donders Institute for Cognitive Neuroimaging, Nijmegen, Netherlands

                  2750.    fMRI-Guided DTI Fiber Tracking: A Verification Study in the Basal Ganglia

Philipp Staempfli¹, ², Carolin Reischauer¹, Thomas Jaermann¹, Anton Valavanis², Spyridon Kollias², Peter Boesiger¹

¹University and ETH Zurich, Zurich, Switzerland; ²University Hospital Zurich, Zurich, Switzerland

                  2751.    Identification of Parallel Hippocampo-Fusiform and Amygdalo-Fusiform Pathways in Living
                                Humans

Charles D. Smith¹, Eren Gultepe², Erbil Akbudak², Nicolas Lori², Thomas Edward Conturo²

¹University of Kentucky, Lexington, Kentucky, USA; ²Washington University, St. Louis, Missouri, USA

                  2752.    Spatial Resolution Dependence of DTI Tractography in Human Occipito-Callosal Region

Mina Kim¹, Itamar Ronen², Kamil Ugurbil¹, Dae-Shik Kim²

¹University of Minnesota, Minneapolis, Minnesota, USA; ²Boston University School of Medicine, Boston, Massachusetts, USA

                  2753.    Efficient Visualization of Fiber Tracking Uncertainty Based on Complex Gaussian Noise

Jan Klein¹, Horst K. Hahn¹, Jan Rexilius¹, Peter Erhard², Matthias Althaus¹, Dieter Leibfritz², Heinz-Otto Peitgen¹

¹MeVis - Center for Medical Diagnostic Systems and Visualization GmbH, Bremen, Germany;
²FB 2 (Chemistry) and Center of Advanced Imaging (CAI), Bremen, Germany

                  2754.    Comparison of Parametric and Nonparametric Probabilistic White Matter Tractography Methods

Mariana Lazar¹, Andrew L. Alexander¹

¹University of Wisconsin, Madison, Wisconsin, USA

                  2755.    Pre-Computed Global Illumination of MR and DTI Data

David C. Banks¹, ², Kevin Beason¹

¹Florida State University, Tallahassee, Florida, USA; ²Harvard Medical School, Boston, Massachusetts, USA

                  2756.    Visualization of Diffusion Anisotropy Using Colored Superquadric Glyphs in DT-MRI

Jinyoung Hwang¹, Yeji Han¹, HyunWook Park¹

¹Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea

                  2757.    3D Visualization of the Diffusion Tensor Ellipsoid in Mouse Brain

Chien-Yuan Lin¹, ², Yi-Hua Hsu², Chung-Yi Hong², Jyh-Hong Chen¹, Chen Chang²

¹Interdisciplinary MRI/MRS Lab, Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan;
²Functional and Micro-MRI Center, Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

                  2758.    DTI&FiberTools: A Complete Toolbox for DTI Calculation, Fiber Tracking, and Combined Evaluation

Björn Wolf Kreher¹, Jürgen Hennig², Kamil A. Il'yasov¹

¹University Hospital Freiburg, Freiburg, Germany; ²University Hospital Freiburg, Freiburg,, Germany

                  2759.    Camino: Open-Source Diffusion-MRI Reconstruction and Processing

Philip A. Cook¹, Yu Bai¹, Shahrum Nedjati-Gilani¹, Kiran K. Seunarine¹, Matt G. Hall¹, Geoffrey J. M Parker²,

Daniel C. Alexander¹

¹University College London, London, UK; ²University of Manchester, Manchester, UK

BOLD: Reactivity and CBV

                  2760.    Comparison of BOLD and CBV-Weighted fMRI Studies Using Multiple-Refocused Spin-Echo

Tao Jin¹, Seong-Gi Kim¹

¹University of Pittsburgh, Pittsburgh, Pennsylvania, USA

                  2761.    Neurovascular Coupling in the Human Visual and Motor Cortices

Peter Anthony Chiarelli¹, Daniel Peter Bulte¹, Daniel Gallichan¹, Peter Jezzard¹

¹Oxford University, Oxford, UK

                  2762.    Spatiotemporal Characteristics of BOLD, CBV and CBF Responses in the Cat Visual Cortex

Tao Jin¹, Jicheng Wang¹, Fuqiang Zhao¹, Ping Wang¹, Michelle Tasker¹, Seong-Gi Kim¹

¹University of Pittsburgh, Pittsburgh, Pennsylvania, USA

                  2763.    Quantitative Characterization of Vascular Non-Linearities in BOLD fMRI

Jacco A. de Zwart¹, Peter van Gelderen¹, J Martijn Jansma¹, Jeff H. Duyn¹

¹National Institutes of Health, Bethesda, Maryland, USA

                  2764.    Sources of Systematic Bias in Hypercapnia-Based CMR_O2 Estimation Using Functional MRI

Peter Anthony Chiarelli¹, Daniel Peter Bulte¹, Stefan Kazimierz Piechnik¹, Peter Jezzard¹

¹Oxford University, Oxford, UK

                  2765.    Model of Vascular Reactivity to Investigate the Basis of Grubb's Relationship Between Cerebral
                                Blood Flow and Volume

Stefan K. Piechnik¹, Peter Chiarelli¹, Peter Jezzard¹

¹University of Oxford, Oxford, Oxfordshire, UK

                  2766.    Does Mild Hypoxia Modulate the Stimulus-Evoked BOLD Response?

Stephen Daniel Mayhew¹, Richard Rogers¹, Paul Dunckley¹, Kyle T. Pattinson¹, Irene Tracey¹, Richard G. Wise¹

¹University of Oxford, John Radcliffe Hospital, Oxford, UK

                  2767.    The Confounding Effects of O₂ on CO₂-Induced Cerebrovascular Reactivity as Measured
                                with BOLD MRI

Alexandra Mardimae¹, ², Marat Slessarev¹, ², Jay Han¹, ², Eitan Prisman², Julien Poublanc², Adrian Crawley²,

Lisa Rodrigues², Joseph Fisher¹, ², David Mikulis²

¹University of Toronto, Toronto, Ontario, Canada; ²University Health Network, Toronto, Ontario, Canada

                  2768.    Vascular Space Occupancy Weighted Imaging with Control of Inflow Effect and Higher
                                Signal-To-Noise Ratio

Wen-Chau Wu¹, Susanne Wegener¹, Richard B. Buxton¹, Eric C. Wong¹

¹University of California, San Diego, La Jolla, California, USA

                  2769.    An Investigation of the VASO Contrast Mechanism Reveals a Novel Method for
                                Quantifying Cerebral Blood Flow

Manus Joseph Donahue¹, Hanzhang Lu², Craig Kenneth Jones¹, James J. Pekar¹, Peter Christian Marie van Zijl¹

¹Johns Hopkins University, Baltimore, Maryland, USA; ²New York University, New York, New York, USA

                  2770.    Resting-State Functional Connectivity Measured by VASO and BOLD

Yihong Yang¹, Hong Gu¹, Elliot A. Stein¹

¹National Institute on Drug Abuse, NIH, Baltimore, Maryland, USA

                  2771.    Cerebral Blood Volume: Measurement and Change

Robert Turner¹, David Thomas¹

¹University College London, London, England, UK

BOLD: Hemodynamic Responses

                  2772.    Hemodynamic Response in Human Central  Olfactory System

Jianli Wang¹, Robert Grunfeld¹, Mark D. Meadowcroft¹, Xiaoyu Sun¹, Erin Zimmermann¹, Paul J. Eslinger¹,

Lukas Ansel¹, Michael B. Smith¹, Qing X. Yang¹

¹Penn State College of Medicine, Hershey, Pennsylvania, USA

                  2773.    Laminar Analysis of the BOLD Hemodynamic Impulse Response

David Ress¹

¹Brown University, Providence, Rhode Island, USA

                  2774.    An Efficient Method for Obtaining Subject-Specific HRF Estimates in Event-Related fMRI

Hannah Devlin¹, Joseph T. Devlin¹, Mark Woolrich¹, Karla L. Miller¹, Peter Jezzard¹

¹University of Oxford, Oxford, Oxon, UK

                  2775.    Reduction of Onset Variability of Event-Related BOLD Responses with
                                Diffusion-Weighted Spin-Echo EPI

Ho-Ling Liu¹, ², Wan-Chun Kuan¹, ³, Tieh-Chi Chu³, Yung-Liang Wan¹, ², Yau-Yau Wai¹, ², Jiun-Jie Wang¹, ²

¹Chang Gung University, Taoyuan, Taiwan; ²Chang Gung Memorial Hospital, Taoyuan, Taiwan; ³National Tsing Hua Univ., Hsinchu, Taiwan

                  2776.    Somatosensory fMRI at 1.5, 3 and 7 T: Measuring BOLD Signal Changes

Wietske van der Zwaag¹, Kay Elizabeth Head¹, Andrew Peters¹, Susan Francis¹, Penny Gowland¹, Richard William Bowtell¹, Peter Morris¹

¹University of Nottingham, Nottingham, UK

                  2777.    The Effect of Global Cerebral Vasodilation on Focal Activation Hemodynamics

Bojana Stefanovic¹, Jan M. Warnking², Karin M. Rylander³, Bruce Pike²

¹NINDS, NIH, Bethesda, Maryland, USA; ²MNI, McGill University, Montreal, Quebec, Canada;
³MNI, McGill University, Montreal, Quebec, Canada

                  2778.    Habituation of the BOLD Response in fMRI of the Human Auditory and Visual Cortex

Mark A. Elliott¹, Luke Bloy¹, Justin Hulvershorn¹

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA

                  2779.    Modeling the Temporal Dynamics of the Positive and Negative BOLD Response

Yashar Behzadi¹, Thomas Liu¹

¹UCSD, La Jolla, California, USA

                  2780.    Intravascular BOLD Signal Contribution to the fMRI ADC Changes in the IVIM Model Regime

Tao Jin¹, Fuqiang Zhao¹, Ping Wang¹, Seong-Gi Kim¹

¹University of Pittsburgh, Pittsburgh, Pennsylvania, USA

                  2781.    Caffeine Reduces the Initial Dip in the Visual BOLD Response

Joy Liau¹, Yashar Behzadi¹, Thomas Liu¹

¹UCSD Center for fMRI, La Jolla, California, USA

                  2782.    An Analysis of Micro- And Macro-Vasculature Blood Flow Characteristics During Graded Stimulation

Yi-Ching Lynn Ho¹, ², Esben Thade Petersen¹, ², Xavier Golay¹, ³

¹National Neuroscience Institute, Singapore, Singapore; ²Nanyang Technological University, Singapore, Singapore;
³A*STAR, Singapore, Singapore

                  2783.    Functional Asymmetry in Human Visual Cortex as Revealed by fMRI

Zhaohui M. Liu¹, ², Xiaoping Hu¹

¹Emory University, Atlanta, Georgia, USA; ²WPI & UMass Medical School, Worcester, Massachusetts, USA

                  2784.    Hemodynamics and Nonlinearities of BOLD Response to Ultrashort Visual
                                Stimulation (5ms - 1s)

Kamil Uludag¹, Baris Yesilyurt¹, Kamil Ugurbil, ^1,2

¹Max-Planck-Institute for biological Cybernetics, Tübingen, Germany; ²Center for Magnetic Resonance Research, Minnesota, Minneapolis, USA

                  2785.    Minimization of Post-Stimulus Undershoot in Heavily Diffusion-Weighted Functional Magnetic
                                Resonance Imaging

Takayuki Obata¹, Moyoko Tomiyasu¹, Kenichi Kashikura², Yoshiyuki Hirano¹, Hiroi Nonaka¹, Masaya Hirano³,

Hiroo Ikehira¹

¹National Institute of Radiological Sciences, Chiba, Japan; ²Gunma Prefectural College of Health Sciences, Maebashi, Gunma, Japan;
³GE Yokogawa Medical Systems, ltd., Tokyo, Japan

                  2786.    Study of Post-Stimulus BOLD Undershoots Between Lateral Geniculate Nucleus and Primary
                                Visual Cortex in Cat Brain

Xiao-Hong Zhu¹, Yi Zhang¹, Nanyin Zhang¹, Jaekeun Park¹, Wei Chen¹

¹CMRR, Radiology Department, University of Minneasota Medical School, Minneapolis, Minnesota, USA

                  2787.    The Contribution of the BOLD Poststimulus Undershoot to Block-Design Subtraction Outcomes
                                in Cognitive fMRI

Jed A. Meltzer¹, Michiro Todd Negishi¹, R. Todd Constable¹

¹Yale University, New Haven, Connecticut, USA

                  2788.    Differential BOLD Hemodynamics in Young and Elderly: Emphasis on Post-Stimulus Undershoot

Kaundinya Gopinath¹, Christina Wierenga², Timothy Conway³, ⁴, Bruce Crosson³, ⁴, Richard Briggs¹

¹UT Southwestern, Dallas, Texas, USA; ²UC San Diego, San Diego, California, USA; ³University of Florida, Gainesville, Florida, USA; ⁴VA Medical Center, Gainesville, Florida, USA

                  2789.    A Two-Compartment BOLD Model of an Infusion of Contrast Agent

Nicholas Paul Blockley¹, Susan T. Francis¹, Penny A. Gowland¹

¹University of Nottingham, Nottingham, UK

                  2790.    Physical Source of fMRI Signal Phase Change: Theory and Simulation

Fuqiang Zhao¹, ², Ping Wang², Tao Jin², Xiaoping Hu¹, Seong-Gi Kim²

¹Emory / Georgia Tech University, Atlanta, Georgia, USA; ²Pittsburgh University, Pittsburgh, Pennsylvania, USA

                  2791.    Source of Phase Change in BOLD and CBV-Weighted fMRI

Fuqiang Zhao¹, ², Ping Wang², Tao Jin², Tsukasa Nagaoka³, Noam Harel³, Xiaoping Hu¹, Seong-Gi Kim²

¹Emory / Georgia Tech University, Atlanta, Georgia, USA; ²Pittsburgh University, Pittsburgh, Pennsylvania, USA;
³University of Minnesota, Minneapolis, Minnesota, USA

                  2792.    Phase Map Based Investigation of Intravoxel Signal Dephasing in Gradient Echo MRI

Alexander Rauscher¹, ², Jan Sedlacik¹, Markus Barth³, Stephan Witoszynskyj⁴, Jürgen R. Reichenbach⁵

¹IDIR, FSU, Jena, Thuringia, Germany; ²Core Unit MR Methods, Jena, Germany; ³Radboud University, Nijmegen, Netherlands;
⁴Medical University, Vienna, Austria; ⁵IDIR, FSU, Jena, Germany

                  2793.    Contribution of Residual BOLD Susceptibility-Induced Local Field Gradients in Diffusion fMRI

Shin-ichi Urayama¹, Toshihiko Aso¹, Takashi Hanakawa¹, Naohide Fukuyama¹, Denis Le Behan¹, ²

¹Kyoto University Graduate School of Medicine, Kyoto, Japan; ²CEA, Orsay, France

fMRI: Combining with Other Modalities

                  2794.    Regional Homogeneity: Epileptic Patients vs. Healthy Volunteers

Huafu Chen¹, ², Xia Zhao², Dezhong Yao¹, Guangming Lu³, zhiqiang zhang³, Jia-Hong Gao²

¹University of Electronic Science and Technology of China, chengdu, sichuan, People’s Republic of China;
²University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA;
³Nanjing General Hospital of PLA, Nanjing, Jiangsu, People’s Republic of China

                  2795.    Simultaneous Recording of ERP and fMRI for Cortical Source Imaging

Chang-Hwan Im¹, Zhongming Liu¹, Nanyin Zhang¹, Wei Chen¹, Bin He¹

¹University of Minnesota, Minneapolis, Minnesota, USA

                  2796.    Simultaneous fMRI and EEG Source Localization with Visual Motion Stimuli

Myung Ho In¹, Soo Yeol Lee¹, Min Hyoung Cho¹, Byung Hee Han¹, Tae-S Kim¹, Jae Yong Han²

¹Kyung Hee University, Yongin, Kyungki, Republic of Korea; ²Gachon Medical School, Incheon, Republic of Korea

                  2797.    Biological Parametric Mapping

Ramon Casanova¹, Ryali Srikanth¹, Aaron Baer¹, Paul J. Laurienti¹, Ann M. Peiffer¹, Jonathan H. Burdette¹,

Satoru Hayasaka¹, Joseph A. Maldjian¹

¹Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA

                  2798.    A Combined NIR and BOLD fMRI Study of Transient Activation and Deactivation

Lin Tang¹, Christopher J. Cannistraci¹, Blake Niederhauser², Malcolm J. Avison¹, John C. Gore¹

¹Vanderbilt University Institute of Imaging Science, Nashville, Tennessee, USA; ²Vanderbilt University, Nashville, Tennessee, USA

                  2799.    Automated Real-Time Tracing of Functional MRI Signals from Multiple Cortical Areas

Seung-Schik Yoo¹, Heather M. O'Leary¹, Hae-Jeong Park², Jong-Hwan Lee¹, HyunWook Park³, Lawrence P. Panych¹,
Ferenc A. Jolesz¹

¹Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA;
²Yonsei University College of Medicine, Seoul, Republic of Korea; ³KAIST, Daejon, Republic of Korea

                  2800.    Fx3MRI: Simultaneous fMRI Scanning in an Open System

Frank Gerardus Cornelis Hoogenraad¹, Elizabeth A. Moore², Frits de Graaf¹, Fredy Visser¹, Johan W. de Jong¹,

Mark Stoesz³, Ad L. Moerland¹

¹Philips Medical Systems, Best, The Netherlands, Netherlands; ²Philips Medical Systems, London, UK, UK;
³Philips Medical Systems, Cleveland, Ohio, USA