fMRI: Measurement Techniques

                  2801.    A New Method to Record 2D- Movement Kinematics During Functional Magnetic
                                Resonance Imaging (fMRI)

Tammar Kushnir¹, Bjoern Hauptmann², Ronen Sosnik³, Oded Smikt³, Eli Okon³, Tamar Flash³, Avi Karni, ¹⁴

¹The Chaim Sheba Medical Center, Tel Hashomer, Israel; ²University Berlin, Berlin, Germany; ³The Weizmann Institute of Science, Rehovot, Israel; ⁴Haifa University, Haifa, Israel

                  2802.    Characterization and Suppression of System Noise Due to Scanner Instability in fMRI Using a
                                SMART PHANTOM BOLD Simulator

Yu Li¹, Qun Zhao², Mark Limkeman¹, Tim Conway², Keith D. White², Keith McGregor², Bruce Crosson²

¹Invivo Diagnostic Imaging, Gainesville, Florida, USA; ²R&D Brain Rehabilitation Research Center, Gainesville, Florida, USA

                  2803.    Reduced fMRI Signal Sensitivity in Motor Areas When Cued by MRI-Compatible Apparatuses

Hsin-Mei Chen¹, Wan-Chun Kuan¹, Yau-Yau Wai¹, ², Yung-Liang Wan¹, ², Ho-Ling Liu¹, ²

¹Chang Gung Univ., Taoyuan, Taiwan; ²Chang Gung Memorial Hospital, Taoyuan, Taiwan

                  2804.    A New Stimulus for Isolating Optokinetic Eye Movement from Smooth Pursuit

Caroline K.L. Schraa-Tam¹, Aad van der Lugt¹, Marion Smits¹, Maarten A. Frens¹, Philippus C.A. van Broekhoven¹, Josef N. van der Geest¹

¹ErasmusMC, Rotterdam, ZH, Netherlands

                  2805.    Evaluation of a Two Compartment Gel Phantom for fMRI

Anders Nilsson¹, Anthony Brian Waites¹, Peter Mannfolk¹, Johan Olsrud¹

¹Lund University, Lund, Sweden

                  2806.    BOLD Phantom Investigations of the Relationship Between Blood Oxygenation, Flow Variation and
                                Intra- And Extra-Vessel Signal Change

Lan Jiang¹, Roderick McColl¹, Ralph P. Mason¹

¹UT Southwestern Medical Center, Dallas, Texas, USA

                  2807.    Improved Design for Absolute Skin Conductance Response Measurement During Motor fMRI

Bradley J. MacIntosh¹, ², Richard Mraz¹, Vladimir Verpakhovski, Simon J. Graham¹, ²

¹Imaging Research, Sunnybrook & Women's CHSC, Toronto, ON, Canada; ²University of Toronto, Toronto, ON, Canada

                  2808.    Predictive Eye Estimation Regression (PEER) for Simultaneous Eye Tracking and fMRI

Stephen Michael LaConte¹, Scott J. Peltier¹, Keith A. Heberlein¹, Xiaoping P. Hu¹

¹Emory University/Georgia Tech, Atlanta, Georgia, USA

                  2809.    Recording of Ultrafast (600-Hz) EEG Oscillations with Amplitudes in the Nanovolt Range
                                    During fMRI- Acquisition Periods

Petra Ritter¹, Frank Freyer¹, Robert Becker¹, Kimitaka Anami², Gabriel Curio¹, Arno Villringer¹

¹Berlin Neuroimaging Center, Berlin, Germany; ²National Center Hospital for Mental, Nervous, and Muscular Disorders, Tokyo, Japan

                  2810.    Failure to Detect Magnetic Source Dephasing Corresponding to ERP Generation

Lin Tang¹, James Christopher Gatenby¹, Malcolm J. Avison¹, John C. Gore¹

¹Vanderbilt University Institute of Imaging Science, Nashville, Tennessee, USA

                  2811.    Using MR Magnitude Imaging to Determine the Spatial Distribution of the Changes of
                                Magnetic Field Induced by Sub-μA Electric Current

Ruiwang Huang¹, Oleg Posnansky¹, Avdo Celik¹, NJ Jon Shah¹

¹Research Centre Juelich, Juelich, Germany

                  2812.    BOLD Sensitivity in Multiecho Sequences

Penny Anne Gowland¹, Richard William Bowtell¹

¹Unversity of Nottingham, Nottingham, UK

                  2813.    On the Effect of Flow and Modest Diffusion Weighting in fMRI

Maarten Versluis¹, ², Hans Hoogduin¹

¹University Medical Center Groningen, University of Groningen, Groningen, Netherlands; ²Philips Medical Systems, Best, Netherlands

                  2814.    Determination of Acoustic Noise Characteristics and Development of Silent EPI for
                                Auditory fMRI

Sebastian Schmitter¹, Michael Amann¹, Lothar Rudi Schad¹

¹Deutsches Krebsforschungszentrum, Heidelberg, Germany

                  2815.    Frequency Stabilization Using Finite Impulse Response Filtering for BOSS fMRI at 3T

Ming-Long Wu¹, Teng-Yi Huang², Pei-Hsin Wu¹, Ming-Chung Chou¹, ³, Cheng-Yu Chen³, Hsiao-Wen Chung¹, ³

¹National Taiwan University, Taipei, Taiwan; ²National Taiwan University of Science and Technology, Taipei, Taiwan; ³Tri-Service General Hospital, Taipei, Taiwan

                  2816.    Transient State BOSS fMRI for a Further Increase in Sensitivity

Pei-Hsin Wu¹, Ming-Long Wu¹, Teng-Yi Huang², Hsiao-Wen Chung¹, ³

¹National Taiwan University, Taipei, Taiwan; ²National Taiwan University of Science and Technology, Taipei, Taiwan;
   ³Tri-Service General Hospital, Taipei, Taiwan

                  2817.    Parallel Imaging in Functional MRI: Comparison of Spiral SENSE and GRAPPA
                                and of Calibration Update Schemes

YoonChung Kim¹, Douglas C. Noll¹

¹University of Michigan, Ann Arbor, Michigan, USA

                  2818.    Feasibility of High Resolution 3D fMRI with Whole Brain Coverage

Yanle Hu¹, Gary H. Glover¹

¹Stanford University, Stanford, California, USA

                  2819.    Partial K-Space Acquisition Method for Improved SNR Efficiency and
                                Temporal Resolution in 3D fMRI

Yanle Hu¹, Gary H. Glover¹

¹Stanford University, Stanford, California, USA

                  2820.    Doubling EPI Resolution by Acquiring Two K-Space Lines Per Readout Gradient
                                Reversal Using TRAIL

Andrew Nicholas Priest¹, ², Enrico De Vita, ²³, Roger John Ordidge³

¹University Hospital Hamburg-Eppendorf, Hamburg, Germany; ²UCL Hospitals NHS Trust, London, UK;
   ³University College London, London, UK

                  2821.    Isotropic, High-Resolution fMRI at 7T Using 3D Stack-Of-Segmented EPI

Karla L. Miller¹, Graham C. Wiggins², Christopher J. Wiggins²

¹Oxford University, Oxford, UK; ²Massachusetts General Hospital, Charlestown, Massachusetts, USA

                  2822.    Echo Train Shifted Multi-Echo FLASH for Functional MRI of the Human Brain at
                                Ultra-High Spatial Resolution

Dirk Voit¹, Jens Frahm¹

¹Biomedizinische NMR Forschungs GmbH, Goettingen, Germany

                  2823.    Effects of Local Susceptibility Gradients on Spiral K-Space Trajectory and
                                Effective Echo–Time (TEeff)

Sumati Krishnan¹, Douglas C. Noll¹

¹University of Michigan, Ann Arbor, Michigan, USA

                  2824.    Counterbalancing Mismatched Magnetization Differences in Functional
                                    Arterial Spin Labeling

Yi-Ching Lynn Ho¹, Esben Thade Petersen¹, Xavier Golay¹

¹National Neuroscience Institute, Singapore, Singapore

                  2825.    Echo Time Dependence of Basal Ganglia Activation at 3T During Motor Task

Stephane Lehericy¹, ², Kamil Ugurbil², Pierre-Francois Van de Moortele²

¹University Pierre et Marie Curie, Paris, IDF, France; ²University of Minnesota, Minneapolis, Minnesota, USA

                  2826.    Magnetic Field Effect of Neuronal Currents on MRI: A Snail Ganglia Study

Tae S. Park¹, Soo Yeol Lee¹, Ji-Ho Park¹, Min Hyoung Cho¹, Byung Hee Han¹, Sang Yeon Lee¹

¹Kyung Hee University, Yongin, Kyungki, Republic of Korea

                  2827.    Theoretical Modeling of MRI Signal Changes Induced by Neuronal Magnetic Fields

Yiqun Xue¹, Jinhu Xiong¹

¹University of Iowa, Iowa City, Iowa, USA

fMRI Noise and Artifact Compensation

                  2828.    Improved Sensitivity of Spinal fMRI by Using Physiological Recordings in General
                                Linear Model Analysis

Patrick W. Stroman¹

¹Queen's University, Kingston, Ontario, Canada

                  2829.    A Bootstrap Method for Removing Aliased Cardiac and Respiratory Effects in
                                Volumetric Resting State Connectivity Data

Mark J. Lowe¹, Ken E. Sakaie¹

¹Cleveland Clinic Foundation, Cleveland, Ohio, USA

                  2830.    Efficacy of Data-Driven Respiration Compensation Methods in fMRI Data at 1.5T

Shuowen Hu¹, Akshay D. Kothari¹, Thomas M. Talavage¹

¹Purdue University, West Lafayette, Indiana, USA

                  2831.    Functional MRI of the Human Amygdala Avoiding Susceptibility Artefacts

Carmen Morawetz¹, Claudia Lange², Petra Holz¹, Jürgen Baudewig¹, Godehard Weniger², Eva Irle², Peter Dechent¹

¹MR-Research in Neurology and Psychiatry, Medical Faculty, Georg-August-University, Göttingen, Germany;
²Department of Psychiatry and Psychotherapy, Medical Faculty, Georg-August-University, Göttingen, Germany

                  2832.    Calibration of fMRI by Simulating BOLD Contrast in the Living Human Brain

Qun Zhao¹, Keith D. White¹

¹University of Florida, Gainesville, Florida, USA

                  2833.    Realistic Computer Generated fMRI Phantoms with Motion Correlated Susceptibility Artifacts

Ning Xu¹, Yong Li¹, J Michael Fitzpatrick¹, Benoit M. Dawant¹, Victorial L. Morgan¹, David R. Pickens¹

¹Vanderbilt University, Nashville, Tennessee, USA

                  2834.    Complex Activation Suppresses Venous BOLD in GE-EPI fMRI Data

Daniel B. Rowe¹, Andrew S. Nencka¹

¹Medical College of Wisconsin, Milwaukee, Wisconsin, USA

                  2835.    Test-Retest Reliability of fMRI Using SmartPhantom

Qun Zhao¹, ², Keith D. White¹, ², Tim Conway¹, ², Keith McGregor¹, Bruce Crosson¹, ²

¹University of Florida, Gainesville, Florida, USA; ²VA Medical Center, Gainesville, Florida, USA

                  2836.    Application of Distortion Correction Procedures to Spin-Echo EPI for fMRI
                                Studies in the Temporal Lobe

Karl Vincent Embleton¹, Matthew A. Lambon Ralph¹, Geoff J. M. Parker¹

¹University of Manchester, Manchester, UK

                  2837.    Local Dynamic Shimming for Slice-Wise Image Acquisition

Jung-Jiin Hsu¹, Gary H. Glover¹

¹Lucas Center for Imaging, Stanford University School of Medicine, Stanford, California, USA

                  2838.    Dynamic Updates of R₂^* and Field Map in fMRI Using a Spiral-In Quick-Spiral-Out
                                K-Space Trajectory

Valur Olafsson¹, Jeffrey A. Fessler¹, Douglas C. Noll¹

¹The University of Michigan, Ann Arbor, Michigan, USA

                  2839.    Double-Sampled EPI in fMRI: A Ghost-Free Acquisition Method with Inherent
                                Field Map Correction Capability

Yi-Ru Lin¹, ², Shang-Yueh Tsai¹, Teng-Yi Huang³, Ming-Long Wu¹, Cheng-Yu Chen⁴, Hsiao-Wen Chung¹, ⁴,

Nan-kuei Chen², Kenneth Kwong⁵

¹National Taiwan University, Taipei, Taiwan; ²Brigham and Women's Hospital - Harvard Medical School, Boston, Massachusetts, USA;
³National Taiwan University of Science and Technology, Taipei, Taiwan; ⁴Tri-Service General Hospital, Taipei, Taiwan;
⁵MGH-HMS-MIT Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA

                  2840.    Quantification of Motion-Related Artifacts in  Simulated fMRI Data Using ICA

Ivana Drobnjak¹, Christian F. Beckmann¹, Mark Jenkinson¹

¹University of Oxford, Oxford, UK

                  2841.    Detection and Correction of Motion-Induced Susceptibility Changes in fMRI Time
                                Series of the Alert  Monkey

Josef Pfeuffer¹, ², Thomas Steudel¹, Hellmut Merkle³, Nikos K. Logothetis¹

¹MPI Biol. Cybernetics, Tuebingen, D, Germany; ²Siemens Medical Solutions, Erlangen, D, Germany; ³NIH/NINDS, Bethesda, Maryland, USA

                  2842.    An Improved ICA Filter for Motion and Ballistocardiogram Artefacts in EEG
                                Recorded in the MR Scanner

Richard Andrew J. Masterton¹, ², David F. Abbott¹, Steve Fleming¹, Graeme D. Jackson¹, ²

¹Brain Research Institute, Melbourne, Victoria, Australia; ²University of Melbourne, Melbourne, Victoria, Australia

                  2843.    Constrained ICA–based Ballistocardiogram and Electrooculogram Artifacts
                                Removal from EEG Signals Acquired Inside MRI

T. Rasheed¹, T.-S. Kim¹, Y.-K. Lee¹, M. H. In¹, W. H. Lee¹, S. Y. Lee¹, S. Y. Lee¹

¹Kyung Hee University, Yongin, Gyeonggi, Republic of Korea

                  2844.    BOLD Baseline 'activity' of Auditory Cortex During Silence

Iain D. Wilkinson¹, Mike D. Hunter¹, Simon B. Eickhoff², Thomas WR Miller¹, Thomas F. Farrow¹, Peter WR Woodruff¹

¹University of Sheffield, Sheffield, South Yorkshire, UK; ²Institut for Medicine (IME), Research Center Juelich, Germany

fMRI Data and Statistical Analysis Method

                  2845.    Sparse PCA a New Method for Unsupervised Analyses of fMRI Data

Karl Sjöstrand¹, ², Torben E. Lund², Kristoffer H. Madsen, ^1,2, Rasmus Larsen¹

¹Technical University of Denmark, Copenhagen, Denmark; ²Copenhagen University Hospital, Hvidovre, Denmark

                  2846.    Accurate Localization of Functional Brain Activity Using Structure Adaptive Smoothing

Karsten Tabelow¹, Jörg Polzehl¹, Volodia Spokoiny¹, Jonathan P. Dyke², Linda A. Heier², Henning U. Voss²

¹Weierstrass Institute for Applied Analysis and Stochastics, Berlin, Germany;
²Weill Medical College of Cornell University, New York, New York, USA

                  2847.    Temporal Clustering Analysis: 3D Versus 2D Approaches in Functional MRI Studies

Xia Zhao¹, Jie Tang², Jia-Hong Gao¹

¹University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA;
²Shenzhen Sinorad Medical Electronics Inc., Shenzhen, Guangdong, People’s Republic of China

                  2848.    Multisubject Fuzzy Cluster Analysis of Functional MRI

Hesamoddin Jahanian¹, ², Seyyed Mohammad Shams², Gholam Ali Hossein-Zadeh², Hamid Soltanian-Zadeh¹, ²

¹Image Analysis Lab. Radiology Dept., Henry Ford Health System, Detroit, Michigan, USA;
²Control and Intelligent Processing Center of Excellence, University of Tehran, Tehran, Iran

                  2849.    Exploring Spatiotemporal Pattern of Human Motor Cortex from fMRI by
                                Self-Clustering Independent Components with Partner Matching

Zhishun Wang¹, Bradley S. Peterson¹

¹Columbia University and NYSPI, New York, New York, USA

                  2850.    Multivariate Analysis of Resting State fMRI in Major Depression Using SeedPLS

Richard Cameron Craddock¹, Svetlana Ye Masalovich², Scott J. Peltier³, Xiaoping Hu³, Helen S. Mayberg²

¹Georgia Institute of Technology, Atlanta, Georgia, USA; ²Emory University, Atlanta, Georgia, USA;
³Georgia Institute of Technology/Emory University, Atlanta, Georgia, USA

                  2851.    2dTCA for Detection of Irregular, Transient fMRI Activation

Victoria L. Morgan¹, Yong Li¹, Bassel Abou-Khalil¹

¹Vanderbilt University, Nashville, Tennessee, USA

                  2852.    Independent Component Analysis in the Presence of Noise in fMRI

Dietmar Cordes¹, Rajesh Nandy²

¹University of Washington, Seattle, Washington, USA; ²UCLA, Los Angeles, California, USA

                  2853.    fMRI Data Analysis by Means of Locally Linear Embedding

Peter Mannfolk¹, Anthony Waites¹, ², Anders Nilsson¹, Johan Olsrud¹

¹Lund University Hospital, Lund, Sweden; ²Brain Research Institute, Melbourne, Australia

                  2854.    Nonparametric Mixture Modeling for Mapping of Brain Activation
                                Using Functional MRI Data

Rajesh Ranjan Nandy¹, Dietmar Cordes²

¹University of California, Los Angeles, California, USA; ²University of Washington, Seattle, Washington, USA

                  2855.    Correlation Analysis of Functional Magnetic Resonance Imaging Data
                                Using FPGA Hardware

Markus Gipp¹, Daniel Gembris¹, Gerhard Lienhart¹, Andreas Kugel¹, Reinhard Männer¹

¹Universität Mannheim, Mannheim, Germany

                  2856.    Distinguishing Robust Brain Activations Using Consistency Maps

Epifanio Bagarinao¹, Kayako Matsuo², Toshiharu Nakai², Yoshio Tanaka¹

¹National Institute of Advanced Industrial Science and Technology, Tsukuba City, Ibaraki, Japan;
²National Center for Geriatrics and Gerontology, Obu, Aichi, Japan

                  2857.    Wavelet-Based Statistical Analysis of fMRI Activation Images

Radu Mutihac¹

¹University of Bucharest, Bucharest, Romania

                  2858.    Statistical Inference for Wavelet-Denoised Statistical Parametric Maps

Ryali Srikanth¹, Ramon Casanova¹, Paul J. Laurienti¹, Ann M. Peiffer¹, Joseph A. Maldjian¹

¹Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA

                  2859.    Dynamic Monitoring of the Brain Activation Under Visual Stimulation Using fMRI -
                                The Advantage of a Sliding Window Analysis

Toshiharu Nakai¹, Epifanio Bagarinao², Kayako Matsuo¹, Yuko Ohgami³, Chikako Kato⁴

¹National Center for Geriatrics and Gerontology, Ohbu, Aichi, Japan; ²AIST, Tsukuba, Ibaragi, Japan; ³Ochanomizu University Graduate School of Humanitics and Science, Bunkyo-ku, Tokyo, Japan; ⁴Toyohashi Sozo College, Toyohashi, Aichi, Japan

                  2860.    Time Course Analysis of T-Values in fMRI of Tool-Use Gestures with and Without Real Tools

Kayako Matsuo¹, Epifanio Tila Bagarinao², Yuko Ohgami³, Toshiharu Nakai¹

¹National Center for Geriatrics and Gerontology, Obu, Aichi, Japan; ²National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan; ³Ochanomizu University, Bunkyo-ku, Tokyo, Japan

                  2861.    The Degree of Bilateral Organization of the Motor Areas Under Unimanual Motor Execution -
                                A Correlation Analysis Approach Using Dynamic Monitoring of T-Statistics

Toshiharu Nakai¹, Epifanio Bagarinao², Kayako Matsuo¹, Yuko Ohgami³, Chikako Kato⁴

¹National Center for Geriatrics and Gerontology, Ohbu, Aichi, Japan; ²AIST, Tsukuba, Ibaragi, Japan;
³Ochanomizu University Graduate School of Humanitics and Science, Bunkyo-ku, Tokyo, Japan; ⁴Toyohashi Sozo College, Toyohashi, Aichi, Japan

                  2862.    Functional MRI Incorporating Information on Voxel-Wise Tissue Volume Fractions

Yihong Yang¹, Wang Zhan¹, Hong Gu¹, Elliot A. Stein¹

¹National Institute on Drug Abuse, NIH, Baltimore, Maryland, USA

                  2863.    Jackknife Assessment of Individual Subject Effects on a Mixed-Effect Group
                                Level fMRI Analysis

Pradeep Chilakamarri Venkat¹, Tom Johnstone¹, Andy Alexander¹, Terry Oakes¹

¹University of Wisconsin-Madison, Madison, Wisconsin, USA

                  2864.    Comparison of the Signal-To-Noise Sensitivity of Different False
                                Discovery Rate Methods

Murali Murugavel¹, John M. Sullivan¹, Karl G. Helmer¹

¹Worcester Polytechnic Institute, Worcester, Massachusetts, USA

                  2865.    Modified Weisskoff Test for Assessing fMRI Stability

Hans Hoogduin¹, Peter Koopmans¹, Remco Renken¹

¹University Medical Center Groningen, University of Groningen, Groningen, Netherlands

                  2866.    Dotslashen: A Bayesian Decision Support System for fMRI Clinical Investigation

Ricardo Z.N. Vêncio¹, ², Liana Guerra Sanches¹, Anita Taub¹, Carolina Araújo¹, Marcelo Maria Felix¹,

Griselda Esther Jara Garrido¹, Carlos Alberto Bragança Pereira², Edson Amaro Jr. ¹

¹Hospital Israelita Albert Einstein, São Paulo, SP, Brazil; ²BIOINFO-USP Núcleo de Pesquisa em Bioinformática, São Paulo, SP, Brazil

Breast

                  2867.    Rapid Fat Suppression in MRI of the Breast with Short Binomial Pulses

Glen Morrell¹

¹University of Utah, Salt Lake City, Utah, USA

                  2868.    Simultaneous Acquisition of Fat and Water Volume Images of the Breast with
                                    T2-Like Contrast Using Vastly Undersampled Isotropic Projection (VIPR) SSFP

Catherine J. Moran¹, Aiming Liu², Youngkyoo Jung¹, Frederick Kelcz¹, Ethan Brodsky¹, Thomas M. Grist¹,

Sean B. Fain¹, Walter F. Block¹

¹University of Wisconsin, Madison, Wisconsin, USA; ²Stanford University, Stanford, California, USA

                  2869.    Improved DCE-MRI in Bilateral Breast Imaging with Fat Suppressed TRICKS

Neville Dali Gai¹, Manojkumar Saranathan², Sandeep Gupta³, David Thomasson¹, Catherine Chow¹

¹National Institutes of Health, Bethesda, Maryland, USA; ²Indian Institute of Science, Bangalore, Karnataka, India;
³GE Healthcare, Hanover, Maryland, USA

                  2870.    The Applicability of K-T GRAPPA for Dynamic Contrast Enhanced MRI

Feng Huang¹

¹Invivo Corporation, Gainesville, Florida, USA

                  2871.    High Resolution Bilateral Dynamic Contrast Enhancement Breast Imaging

Jin Hyung Lee¹, Charles H. Cunningham¹, Brian A. Hargreaves¹, Logi Vidarsson¹, Dwight G. Nishimura¹,

John M. Pauly¹, Bruce L. Daniel¹

¹Stanford University, Stanford, California, USA

                  2872.    “Direct Imaging” Method for Bilateral Breast Imaging Using Micro-Strip Coils

Jian-xiong Wang¹, Elizabeth Ramsay¹, Yangmei Li¹, Donald B. Plewes¹

¹Sunnybrook & Women's College Health Science Centre, Toronto, ON, Canada

                  2873.    Contrast Agent Enhanced Breast Imaging with a Combined 3D Dual Echo Dixon
                                and Parallel Imaging Technique

Jingfei Ma¹, Anthony T. Vu², Jong Bum Son¹, ³, Yinan Liu¹, ³, Adrian Knowles², Jason Polzin², Constance Lehman⁴

¹University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA; ²GE Healthcare Technologies, Waukesha, Wisconsin, USA;
³Texas A & M University, College Station, Texas, USA; ⁴Seattle Cancer Care Alliance, Seattle, Washington, USA

                  2874.    Comparisons of Water-To-Fat Ratios in Malignant, Benign Breast Lesions, and Normal
                                Breast Parenchyma: An In Vivo Proton MRS Study

Sunitha B. Thakur¹, Lia Bartella¹, Nicole M. Ishill¹, Elizabeth A. Morris¹, Laura Liberman¹, David D. Dershaw¹, Hedvig Hricak¹,
Jason A. Koutcher¹, Wei Huang¹

¹Memorial Sloan Kettering Cancer Center, New York, New York, USA

                  2875.    Breast Cancer Diagnosis Using Single-Voxel MRS Measurement of Apparent
                                Diffusion Coefficient of Water

Curtis Andrew Corum¹, Adeka D. McIntosh¹, Angela L. Styczynski¹, Nathaniel J. Powell¹, Janice R. Kruse¹,

Patrick J. Bolan¹, Michael Nelson¹, Tim H. Emory¹, Douglas Yee¹, Todd M. Tuttle¹, Lenore I. Everson¹,

Michael Garwood¹

¹University of Minnesota, Minneapolis, Minnesota, USA

                  2876.    Can MRS Improve Our Ability to Distinguish Between Benign and Malignant Lesions?

Richard Kinh Gian Do¹, Linda Moy¹, Nouha Salibi², Cecilia L. Mercado¹, Kelly Anne McGorty¹, Mary Kitazono³, Elizabeth Hecht¹

¹New York University, New York, New York, USA; ²Siemens Medical Solutions, St. Louis, Missouri, USA;
³Keck School of Medicine of USC, Los Angeles, California, USA

                  2877.    Localized ¹³C NMR Spectroscopy in the Human Breast In Vivo

Isabelle valentine Iltis¹, Patrick J. Bolan¹, Hellmut Merkle¹, Carl J. Snyder¹, Curtis Andrew Corum¹, Kamil Ugurbil¹,
Michael Garwood¹, Pierre-Gilles Henry¹

¹Center for Magnetic Resonance Research, Minneapolis, Minnesota, USA

                  2878.    Improved Measurement of Choline-Containing Compounds in Malignant Breast
                                Tumors Using Multiple Long-TEs Averaging MR Spectroscopy

Hyun-Man Baik¹, Min-Ying Su¹, O. Nalcioglu¹

¹University of California-Irvine, Irvine, California, USA

                  2879.    Change of ADC Value of Breast Cancer in Patients Undergoing Neoadjuvant Chemotherapy:
                                Preliminary Study

Guangwei Jin¹, Ningyu An¹, Youquan Cai¹

¹PLA General Hospital, Beijing, People’s Republic of China

                  2880.    Breast Cancer Evaluation Using Diffusion Weighted MR-Imaging –
                                Prior to and Following Chemotherapy   Can DWI Predict Chemotherapeutic Response?

Paul Weatherall¹, Qi Peng², Yao Ding³, Roderick W. McColl³, Debu Tripathy³, Jonathan M. Chia⁴, Ralph P. Mason³

¹University of Texas Southwestern Medical Center, Dallas, Texas, USA; ²University of Texas Health Science Center San Antonio, San Antonio, Texas, USA; ³UT Southwestern Medical Center, Dallas, Texas, USA; ⁴Philips Medical Systems, Dallas, Texas, USA

                  2881.    Do Diffusion Changes Occur Prior to Size Changes in Breast Tumours Undergoing
                                Neoadjuvant Chemotherapy?

Martin Darren Pickles¹, Peter Gibbs¹, Martin Lowry¹, Lindsay W. Turnbull¹

¹University of Hull, Hull, East Yorkshire, UK

                  2882.    The Role of Apparent Spin-Spin Relaxation in Assessing Response to Treatment in
                                    Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy

Martin Darren Pickles¹, Martin Lowry¹, Lindsay W. Turnbull¹

¹University of Hull, Hull, East Yorkshire, UK

                  2883.    Contrast-Enhanced MRI for Assessing the Response of Invasive Breast Cancer to
                                Neoadjuvant Chemotherapy

Alan Howard Stolpen¹, Jeong Mi Park¹, Mark W. Karwal¹, Megha Garg¹

¹University of Iowa, Iowa City, Iowa, USA

                  2884.    Fast Exchange Regime Analysis of the Response to Treatment in Human Breast Cancer

Thomas Yankeelov¹, Martin Lepage², A. Bapsi Chakravarthy¹, Kenneth J. Niermann¹, Cheryl R. Herman¹,

Kevin McManus¹, Mark C. Kelley¹, Ingrid Mayer¹, Ingrid Meszoely¹, John C. Gore¹

¹Vanderbilt University, Nashville, Tennessee, USA; ²Universite de Sherbrooke, Sherbrooke, QC, Canada

                  2885.    Volumetric Texture Analysis of DCE-MR Images of the Breast Using Gray-Level
                                Co-Occurrence Matrix Method

Weijie Chen¹, Maryellen L. Giger¹

¹The University of Chicago, Chicago, Illinois, USA

                  2886.    Textural Analysis Optimisation in MRI of the Breast

Tom Beach¹, Peter Gibbs¹, Martin D. Pickles¹, Lindsay Turnbull¹

¹University of Hull, Hull, UK

                  2887.    Bootstrap Ensemble Neural Networks in MRI of the Breast

Peter Gibbs¹, Muthyala Sreenivas¹, Andrew Hunter², Lindsay Turnbull¹

¹University of Hull, Hull, UK; ²Lincoln University, Lincoln, UK

                  2888.    Breast MRI Lesion Classification: Comparison Between Human Readers and
                                Backpropagation Neural Network (BNN)

Lina Arbash Meinel¹, Alan Stolpen², Kevin Berbaum², Laurie Fajardo², Joseph M. Reinhardt³

¹Philips Research USA, Chicago, Illinois, USA; ²University of Iowa Hospitals, Iowa City, Iowa, USA; ³University of Iowa, Iowa City, Iowa, USA

                  2889.    Artificial Neuronal Network Analysis of Neoadjuvant Chemotherapy Response Using
                                Quantitative Morphological, Texture and Enhancement Kinetic Parameters

Yong Chu¹, Ke Nie¹, Hon J. Yu¹, Jeon-Hor Chen¹, Orhan Nalcioglu¹, Min-Ying Su¹

¹University of California, Irvine, California, USA

                  2890.    Clinical Evaluation of Combining Dynamic Contrast Enhancement MRI and Diffusion
                                    Weighted MR Imaging for Diagnosis of Breast Lesion

Xiaopeng Zhang¹, Jie LI¹, Yinshi Sun¹, Lei Tang², Kun Cao³

¹Beijing Cancer Hospital,Peking University School of Oncology, Beijing, People’s Republic of China;
²Beijng Cancer Hospital, Peking University School of Oncology, Beijing, People’s Republic of China;
³Beijing Cancer Hospital, Peking University School of Oncology, Beijing, People’s Republic of China

                  2891.    Differentiation of Malignant from Bening Breast Lesions by Diffusion-Weighted
                                Imaging with ASSET Technique

Guangwei Jin¹, Ningyu An¹, Yu Cai¹

¹PLA General Hospital, Beijing, People’s Republic of China

                  2892.    MR-Elastography for Breast Lesion Characterization - The Effect of Rheology on
                                Its Diagnostic Impact

Ralph Sinkus¹, Katja Siegmann², Tanja Xydeas², Jeremy Bercoff³, Mickael Tanter¹, Benjamin Robert¹, Mathias Fink¹

¹Laboratoire Ondes et Acoustique, Paris, France; ²University Tuebingen, Tuebingen, Germany; ³SuperSonic Imagine, Aix-en-Provence, France

                  2893.    Assessment of Magnetization Transfer and Tissue Blood Flow Imaging in Human
                                Breasts Tissue by GREAST

Ka-Loh Li¹, Lisa J. Wilmes¹, Jessica Gibbs¹, Eric Han², Greg Zaharchuk¹, Christopher P. Hess¹, Bonnie Joe¹,

Nola Hylton¹

¹University of California, San Francisco, San Francisco, California, USA;
²GE Healthcare Global Applied Science Laboratory,, Menlo Park, California, USA

                  2894.    The Value of T2 Imaging in Establishing Benignancy or Malignancy of Enhancing Lesions
                                Detected by Gd-Enhanced Breast MRI

Frederick Kelcz¹, Mai A. Elezaby¹

¹University of Wisconsin, Madison, Wisconsin, USA

                  2895.    Parametric Mapping of Contrast Kinetics from Rapid Radial DCE-MR Breast Images

Lawrence Dougherty¹, Hee Kwon Song¹, Peter J. Moate¹, Linda White Nunes², Mark A. Rosen¹, Raymond C. Boston¹

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA; ²Pennsylvania Hospital, Philadelphia, Pennsylvania, USA

                  2896.    Volumetric Mapping of the Longitudinal to Transverse Relaxation Times Ratio
                                (T1/T2) of the Entire Human Breast

Jaroslaw Nicholas Tkacz¹, Yommy Chiu², Hernan Jara²

¹Boston University Medical Center, Boston, Massachusetts, USA;
²Boston University, Boston, Massachusetts, USA

                  2897.    Breast MR Electrical Impedance Tomography Toward Breast Cancer Imaging

H. Y. Heo¹, Y. Cho¹, B. I. Lee¹, S. H. Oh¹, T.-S. Kim¹, S. Y. Lee¹, E. J. Woo¹

¹Kyung Hee University, Yongin, Gyeonggi, Republic of Korea

                  2898.    Study of Marker Component for Low Susceptibility Tri-Modalities
                                Breast Tumor Localization

Yangmei Li¹, Claire Holloway¹, Jian-Xiong Wang¹, Donald B. Plewes¹

¹Sunnybrook and Women's Health Science Centre, University of Toronto, Toronto, Ontario, Canada

                  2899.    Negative Pressure Fixation Device to Reduce Motion Artifacts on
                                Contrast-Enhanced MR Imaging of the Breast

Asha Balakrishnan¹, Daniel F. Kacher², Steven E. Chavoustie³

¹Massachusetts Institute of Technology, Cambridge, Massachusetts, USA;
²Brigham and Women's Hospital, Boston, Massachusetts, USA; ³University of Miami, Miami, Florida, USA

                  2900.    7T High Resolution Breast MRI

Ray F. Lee¹, Linda Moy¹, Ryan Brown², KellyAnn McGorty¹, Cornel Stefanescu¹, Yi Wang², Naomi Peck¹

¹New York University, New York, USA; ²Conell University, New York, USA

                  2901.    Coregistration of Contrast Enhanced MRI and Broadband Diffuse
                                Optical Spectroscopy for Characterizing Breast Cancer

Min-Ying Su¹, Hon J. Yu¹, Natasha S. Shah¹, David J-B Hsiang¹, Rita S. Mehta¹, Albert E. Cerussi¹,

Bruce J. Tromberg¹, Orhan Nalcioglu¹

¹University of California, Irvine, California, USA

                  2902.    Diffusion Tensor Imaging of the Breast: Preliminary Clinical Findings

Savannah C. Partridge¹, JoAnn M. Lorenzo¹, Sue Peacock¹, Bonnie M. Thursten², John S. McCloskey²,

Wendy B. DeMartini¹, Peter R. Eby¹, Eric L. Rosen¹, Constance D. Lehman¹

¹University of Washington, Seattle, Washington, USA; ²Seattle Cancer Care Alliance, Seattle, Washington, USA

Perfusion and Permeability in Cancer Models

                  2903.    Distribution of Steady State Contrast Agent Concentration and Interstitial
                                Fluid Pressure in Human Xenografts

Yaron Hassid¹, Raanan Margalit¹, Edna Haran Furman¹, Maya Dadiani¹, Hadassa Degani¹

¹Weizmann Institute of Science, Rehovot, Israel

                  2904.    Parallel Observation of Left Ventricular Arterial Input Function and Brain
                                Perfusion in Rats Using a Multi-Coil System

Stephen Pickup¹, Sanjeev Chawla¹, Dae-Hong Kim¹, Harish Poptani¹

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA

                  2905.    Early Effects of Combretastatine A-4-P on Rat Bladder Tumor Heterografts Assessed by
                                Combined Carbogen Based fMRI and T2 Mapping

Carole D. Thomas¹, Christine Walczak¹, Julia Kaffy², Renée Pontikis², Jacqueline Jouanneau², Andreas Volk¹

¹Institut Curie, Orsay, France; ²Institut Curie, Paris, France 

Melanie Heilmann¹, Jean-Luc Dimicoli¹, Carole D. Thomas¹, Christine Walczak¹, Andreas Volk¹

¹Institut Curie - Research Center, Orsay, France

                  2907.    Direct Comparison of Macromolecular Contrast Agent Vistarem with Dotarem for Detecting Drug
                                Effects on Tumor Vasculature by DCE MRI

Peter R. Allegrini¹, Claudia Weidensteiner¹, Paul M.J. McSheehy¹

¹Novartis Inst. for BioMedical Research, Basel, BS, Switzerland

                  2908.    Longitudinal Studies of Angiogenesis in Hormone Dependent Shionogi Tumours

Trevor Wade¹, Piotr Kozlowski²

¹University of British Columbia, Vancouver, British Columbia, Canada;
²Prostate Centre at Vancouver General Hospital, Vancouver, British Columbia, Canada

                  2909.    DCE-MRI for Evaluation of Response to Gefitinib: Comparison of Two Treatment Regimens
                                in a Breast Cancer Model

Lisa J. Wilmes¹, Ka-Loh Li¹, Sheye Aliu¹, Donghui Wang¹, Byron C. Hann¹, Mark M. Moasser¹, Nola M. Hylton¹

¹University of California San Francisco, San Francisco, California, USA

                  2910.    Monitoring Micro-Vasculature Damage Induced by Radiotherapy on Mouse Breast Carcinomas
                                Using DCE-MRI

Martin Pellerin¹, Luc Tremblay¹, Benoit Paquette¹, Martin Lepage¹

¹Université de Sherbrooke, Sherbrooke, QC, Canada
 

                  2911.    DCE MRI Detected Differential Response to ZD6126 of Metastatic Versus Indolent
      Human Melanoma

Rong Zhou¹, Hui Qiao¹, Lin Z. Li¹, Xin Li², Phyllis Wachsberger³, Charles S. Springer, Jr², Mary JC Hendrix⁴,

Jerry D. Glickson¹

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA; ²Oregon Health & Science University, Portland, Oregon, USA;
³Thomas Jefferson University, Philadelphia, Pennsylvania, USA; ⁴University of Chicago, Chicago, Illinois, USA

                  2912.    Short-Term Treatment with the Triple Angiokinase Inhibitor, BIBF 1120, Affects Vascular Permeability
                                and Perfusion of Human Tumor Xenografts in Nude Mice

Martin Krssak¹, Monika Kriz¹, Frank Hilberg¹

¹Boehringer Ingelheim Austria, Vienna, Austria

                  2913.    MRI of Calu-6 Lung Tumors for the Assessment of the Anti-Vascular Activity of MN-029

Nathalie Just¹, Veronique Rancier¹, Nicolas Guilbaud¹, Philippe Genne¹, Kenneth Locke²

¹Oncodesign Biotechnology, Dijon, France; ²MediciNova Inc, San Diego, California, USA

Cancer Models: Assessment of Vascular Function

                  2914.    Nonlinear Correction of Arterial Input Function Measured with Spoiled Gradient Echo Sequences

Matthias C. Schabel¹

¹University of Utah, Salt Lake City, Utah, USA

                  2915.    Modelling DCE-MRI Arterial Input Functions in Rats

Deirdre McGrath¹, Tony Lacey², Daniel Bradley², Chris Taylor¹, Geoff Parker¹

¹University of Manchester, Manchester, Lancashire, UK; ²Astrazeneca, Alderley Park, Macclesfield, Cheshire, UK

                  2916.    An Adaptive Bayesian MRF Approach for DCE-MR Imaging

Volker J. Schmid¹, Brandon Whitcher², N. Jane Taylor³, Anwar R. Padahni³, Guang-Zhong Yang¹

¹Imperial College London, London, England, UK; ²GlaxoSmithKline, Greenford, England, UK; ³Mount Vernon Hospital, Northwood, England, UK

                  2917.    Tissue Assessment in Gliomas: Comparison of Tumor Blood Volume, Vascular Permeability
                                by Perfusion-Weighted MR Imaging and Tl-201 SPECT

Hidemasa Uematsu¹, Tatsuro Tsuchida¹, Hirohiko Kimura¹, Nobuyuki Kosaka¹, Harumi Itoh¹

¹University of Fukui, Fukui, Japan

                  2918.    Determination of Maturity and Functionality of Tumor Vasculature by MRI: Correlation Between
                                BOLD MRI and DCE MRI Using P792 in Experimental Fibrosarcoma Tumors

Christine Baudelet¹, Greg O. Cron¹, Bernard Gallez¹

¹Catholic University of Louvain, Brussels, Belgium

                  2919.    The Role of Vessel Maturation and Vessel Functionality in Spontaneous Fluctuations
       of T2*-Weighted GRE Signal Within Tumors

Christine Baudelet¹, Greg O. Cron¹, Réginald Ansiaux¹, Nathalie Crokart¹, Julie DeWever¹, Olivier Feron¹,

Bernard Gallez¹

¹Catholic University of Louvain, Brussels, Belgium

                  2920.    DCEMRI Detects Effects of Tumors on Adjacent Normal Tissue That Reflect Tumor Grade

Xiaobing Fan¹, Milica Medved¹, Jonathan N. River¹, Marta Zamora¹, Gregory S. Karczmar¹

¹University of Chicago, Chicago, Illinois, USA

                  2921.    Susceptibility MRI of Vascular Function and Therapeutic Response in LS174T Colorectal
                                Carcinomas Grown Orthotopically in Murine Liver

Tammy Louise Kalber¹, Anderson Joseph Ryan², John R. Griffiths¹, John C. Waterton², Simon P. Robinson¹

¹St. George's, University of London, London, UK; ²AstraZeneca, Alderley Park, Macclesfield, UK

                  2922.    Lineshape and Susceptibility in a Rat Glioma Monitored by Echo Planar Spectroscopic Imaging

Gary V. Martinez¹, Maria Luisa Garcia Martin¹, ², Gregory S. Karczmar³, Jeffrey R. Alger⁴, Nikhil Rajguru¹,

Robert J. Gillies¹

¹University of Arizona, Tucson, Arizona, USA; ²CSIC-UAM, Madrid, Spain; ³University of Chicago, Chicago, Illinois, USA; ⁴UCLA, Los Angeles, California, USA

                  2923.    MR Perfusion and 1H Spectroscopic Imaging in the Longitudinal Evaluation of Brain Tumor
      Angiogenesis

Narasimha Shastry Akella¹, Steven D. Buchthal¹, Louis Burt Nabors¹, Jan A. den Hollander¹

¹University of Alabama at Birmingham, Birmingham, Alabama, USA

                  2924.    Quantitative Assessment of Tumor Microstructure in Canine Brain Using High Resolution DTI
                                Microimaging

Jian-Ming Zhu¹, Ping Wang¹, John L. Robertson², John H. Rossmeisl, Jr. ², Michael E.C Robbins¹, Edward G. Shaw¹

¹Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA;
²Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg, Virginia, USA

                  2925.    Hypoxia Increases Endothelial Cell Invasion and Migration

Barjor Gimi¹, Noriko Mori¹, Zaver M. Bhujwalla¹

¹The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

                  2926.    MR Imaging of Bone Marrow-Derived Mesenchymal Stem Cells Incorporation Into Tumor
                                Vasculature in Prostate Cancer Models

Lyubov Ostrovskaya¹, Yoshinori Kato¹, Piotr Walczak¹, Baasil Okollie¹, Jeff W. Bulte¹, Dmitri Artemov¹

¹Johns Hopkins University, Baltimore, Maryland, USA

                  2927.    Monitoring of Cellular Uptake of Gadollinium by Dendritic Cells Useful for Tracking the Cell
                                Trafficking in Tumor Using MRI

Raghvendra S. Sengar¹, Patricia Griffin¹, Daniel Steed¹, Tianbing Yang², Lorissa Villa², William Chambers²,

Erik Craig Wiener²

¹University of Pittsburgh Cancer Institute, Pittburgh, Pennsylvania, USA;
²University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA

DCE-MRI in Cancer: Clinical and Analysis

                  2928.    DCE-MRI Perinecrotic Imaging Biomarker Signature and Observed Interpatient Heterogeneity

Dee Wu¹, Yi Zheng¹, Susan Edwards¹, Syed Rahmannan¹, William TC Yuh², Nina Mayr²

¹University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA; ²Ohio State University, Columbus, Ohio, USA

                  2929.    Incorporation of Explicit Arterial Input Function for DCE-MRI Quantification: Use in Human
                                Trial of Sorafenib in Renal Cell Carcinoma

Mark Rosen¹, Keith Flaherty¹, Dan Heitjan¹, Brian Schwartz², Peter O'Dwyer¹

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA; ²Bayer Pharmaceutical Corp, West Haven, Connecticut, USA

                  2930.    Pixel-Based Quantitative Analysis of Dynamic Contrast-Enhanced MRI of Lung Tumors

Yu-Jen Chen¹, Woei-Chyn Chu¹, Wen-Yih Isaac Tseng²

¹Institute of Biomedical Engineering, National Yang-Ming University, Taipei, Taiwan;
²Center for Optoelectronic Biomedicine, National Taiwan University College of Medicine, Taipei, Taiwan

                  2931.    Dynamic Contrast Enhanced MRI as a Priori Predictor of Response in Head and Neck Squamous
                                Cell Carcinoma: Initial Analysis

Amita Shukla-Dave¹, H. Stambuk¹, Y. Wang¹, S. Karimi¹, Y. B. Su¹, D. G. Pfister¹, N. Lee¹, J. A. Koutcher¹

¹Memorial Sloan-Kettering Cancer Center, New York, USA 


 

Aleksandra Radjenovic¹, Barbara J. G. Dall², Steven Frederick Tanner¹, Sarah E. Bacon², Daina Dambitis²,

John Peter Ridgway², Michael A. Smith³

¹University of Leeds, Leeds, UK; ²Leeds General Infirmary, Leeds, UK; ³University of Teesside, Middlesbrough, UK

                  2933.    The Extent and Severity of Vascular Leakage as Evidence of Tumor Aggressiveness in
                                High-Grade Gliomas

Yue Cao¹, Vijaya Nagesh¹, Daniel Hamstra¹, Christina I. Tsien¹, Ross D. Brian¹, Thomas L. Chenevert¹, Larry Junck¹, Theodore S. Lawrence¹

¹University of Michigan, Ann Arbor, Michigan, USA

                  2934.    Radiologist Selection of Tumor Regions of Interest for Dynamic Contrast Enhanced MRI Analysis:
                                Effect on Reproducibility and Spread of Modelled and Non-Modelled Parameters

Adrian Tang¹, David Collins², James d'Arcy¹, Martin Leach¹, Simon Walker-Samuel¹, Toni Wallace², Nandita deSouza¹

¹Institute of Cancer Research, Sutton, Surrey, UK; ²Royal Marsden NHS Foundation Trust, Sutton, Surrey, UK

                  2935.    What is the Optimal Cohort Size for a Reproducibility Study of Dynamic Contrast-Enhanced MRI?

N Jane Taylor¹, James A. d'Arcy², Simon Walker-Samuel², David J. Collins², Benjamin Knowles², J James Stirling¹, Toni Wallace²,
Dow-Mu Koh², Adrian Tang², Chooi Lee², Martin O. Leach², Gordon J S Rustin¹, Anwar R. Padhani¹

¹Mount Vernon Hospital, Northwood, Middlesex HA6 2RN, UK; ²Royal Marsden Hospital, Sutton, Surrey SM2 5PT, UK

                  2936.    Reproducibility of Pharmacokinetic Parameters Using Different Input Functions in a
                                Multi-Center Non-Expert Phase I Oncology Clinical Trial

Vahan Sharoyan¹, David White², Radhika Sivaramakrishna¹, Susan Galbraith³, Ali Guermazi¹, Caroline Reinhold¹, Anwar Padhani ^{1, 4}

¹Synarc, Inc., San Francisco, California, USA; ²Synarc, Inc.,, San Francisco, California, USA;
³Bristol Myers Squibb Company, Princeton, New Jersey, USA; ⁴Paul Strickland Scanner Centre, Mount Vernon Hospital, Northwood, Middlesex, UK

                  2937.    Optimal Quantification of DCE-MRI Data Using Reference Tissue Normalisation

Simon Walker-Samuel¹, Benjamin R. Knowles¹, James A. d'Arcy¹, Neil J. Smith², Gina Brown³, Martin O. Leach¹, David J. Collins¹

¹Institute of Cancer Research, Sutton, Surrey, UK; ²Mayday University Hospital, Thornton Heath, Surrey, UK;
³Royal Marsden and NHS Foundation Trust, Sutton, Surrey, UK