Cancer Models: MRI/MRS Assessment
Room 4A Monday 14:00 - 16:00

 

Time

Prog #

Computer#

 
14:00 3173 16

Difference in Early Intratumoral Changes Induced by Single Dose and Fractionated Radiotherapy in Rat

Rhabdomyosarcoma Measured with Diffusion- And Perfusion-Weighted Magnetic Resonance Imaging

Frederik De Keyzer1, Vincent Vandecaveye1, Jill Eckelmans1, Feng Chen1, Ronald R. Peeters1, Pascal Hamaekers1,

Yicheng Ni1, Robert Hermans1, Sandra Nuyts1, Willy Landuyt2, Hilde Bosmans1

1University Hospitals Leuven, Leuven, Vlaams-Brabant, Belgium; 2Catholic University of Leuven (KUL), Leuven, Vlaams

Brabant, Belgium

14:00 3174 17

Comparison of T and Diffusion Response Following Chemotherapy in Mouse EL4 Tumors at 9.4 T

Mikko I. Kettunen1, De-En Hu1, Kevin M. Brindle1

1University of Cambridge, Cambridge, UK
14:00 3175 18

Evaluation of Salmonella-Based Suicide Gene Transfer in a Rodent Tumor Model Using In Vivo 19F MR

Spectroscopy

Tom Dresselaers1, Jan Theys2, Ludwig Dubois2, Willy Landuyt1, Paul Van Hecke1, Philippe Lambin2

1K.U.Leuven, Leuven, Belgium, Belgium; 2Maastricht Radiation Oncology Lab/GROW, Maastricht, The Netherlands,

Netherlands

14:30 3176 18

The PPARγ Inhibitor GW9662 Attenuates Phenylbutyrate-Induced Lipid Metabolite Accumulation in DU145

Prostate Cancer Cells

Matthew Milkevitch1, Nancy J. Beardsley1, Edward J. Delikatny1

1University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, U
14:30 3177 17

Apparent Diffusion Coefficient  Predicts Survival in  a Transgenic Model of Glioma

Patrick McConville1, Jonathan B. Moody1, Alicia R. Kreger1, William L. Elliott1, Wilbur R. Leopold1, Brian D. Ross2, Eric

C. Holland3

1Molecular Imaging Research, Inc., Ann Arbor, Michigan, USA; 2University of Michigan, Ann Arbor, Michigan, USA; 3Memorial Sloan-Kettering Cancer Center, New York, New York, USA
14:30 3178 16

Dose Response of Rat GH3 Prolactinomas to 5,6-Dimethylxanthenone-4-Acetic Acid (DMXAA) Assessed by

Dynamic Contrast Enhanced MRI

Dominick John McIntyre1, Lesley D. McPhail1, Christian Ludwig2, Philip Kestell3, John Richard Griffiths1,

Lloyd R. Kelland4, Simon Philip Robinson1

1St George's, University of London, London, UK; 2University of Birmingham, Birmingham, UK; 3University of Auckland, Auckland, New Zealand; 4Antisoma Research Ltd, London, UK
15:00 3179 16

Assesing the Response of Pre-Clinical Tumor Models to Anti-Neoplastic Therapies Using Functional Diffusion

Mapping (FDM)

Bradford A. Moffat1, Daniel E. Hall1, Benjamin Hoff1, Thomas L. Chenevert1, Brian D. Ross1

1University of Michigan, Ann Arbor, Michigan, USA
15:00 3180 17

Assessment of Emerging Chemotherapeutic Tumor Resistance to BCNU

Victor D. Schepkin1, Kuei C. Lee1, Kyle Kuszpit1, Mukilan Muthuswami1, Thomas L. Chenevert1, Alnawaz Rehemtulla1,

Brian D. Ross1

1University of Michigan Medical School, Ann Arbor, Michigan, USA
15:00 3181 18

Choline Phospholipid Metabolism in Human Ovarian Tumor Progression: A MRS Study

Egidio Iorio1, Alessandro Ricci1, Delia Mezzanzanica2, Francesca Spadaro1, Carlo Ramoni1, Rossella Canese1, Carmela

Rozera1, Massimo Spada1, Filippo Belardelli1, Sandra D'Ascenzo3, Vincenza Dolo3, Silvana Canevari2, Franca Podo1

1Istituto Superiore di Sanità, Roma, Italy; 2Istituto Nazionale Tumori, Milano, Italy; 3University of L'Aquila, L'Aquila, Italy
15:30 3182 18

Magnetic Resonance Spectroscopy: A Non-Invasive Tool for Monitoring Histone Deacetylase Inhibition

Madhuri Sankaranarayanapillai1, William PingYiu Tong1, Ashutosh Pal1, William G. Bornmann1, Juri G. Gelovani1,

Sabrina M. Ronen1

1UT M.D.Anderson Cancer Center, Houston, Texas, USA

15:30 3183 17

Accelerated Evaluation of Tumor Treatment Response by Diffusion MRI

Jonathan Bryan Moody1, Patrick James McConville1, Richard J. Lister1, Bradford A. Moffat2, Thomas L. Chenevert2,

Alnawaz Rehemtulla2, Brian D. Ross2, William L. Elliott1, Wilbur R. Leopold1

1MIR Preclinical Services, Ann Arbor, Michigan, USA; 2University of Michigan, Ann Arbor, Michigan, USA
15:30 3184 16

Statistical Power of Two Quantitative Biomarkers for Analysis of DCE-MRI Studies of Agents Targeting Tumour

Vasculature

Dominick John McIntyre1, Simon Phili Robinson1, Philip Worthington2, John Richard Griffiths1, John C. Waterton2

1St George's, University of London, London, UK; 2AstraZeneca, Alderley Park, Macclesfield, UK