Overview:
This course will consist of four one-hour sessions given over 4 days: A
discussion of various theoretical aspects of high static B0 fields and
corresponding higher radio frequency B1 magnetic fields and
the challenges that they pose with respect to human MRS and MRI at such
fields; selected applications of MRI at high fields with emphasis on the
challenges of body imaging, and on contrast mechanisms such as T1,
susceptibility, MRA and BOLD; the challenges of performing heteronuclear
spin-spin decoupling in human MRS at high fields, and the benefits of
high fields for the technology for in vivo detection of the
neurotransmitters GABA and glutamate/glutamine; and the bioeffects,
regulation and management issues as they relate to high static fields.
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Educational Objectives:
Upon completion of this session, participants should be able to: |
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· |
Describe the general behavior of B0
and B1 fields in the human body when the Larmor
frequency is of the order of or greater than 100 MHz; |
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· |
List the problems faced in trying to obtain a
homogeneous B0 field and a B1 field; |
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· |
Recognize the challenges of developing RF coils
for high field applications; |
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• |
Recognize the challenges of whole-body imaging at
high fields and list potential solutions; |
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• |
List recent methodological advances for detecting
neurotransmitters by MRS at high fields; |
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· |
Recognize the challenges of implementing
heteronuclear spin-spin decoupling at high static fields; |
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• |
Describe the benefits of high field for BOLD
contrast; |
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• |
Describe the interaction between high magnetic
fields and biological systems; and |
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• |
List organizations responsible for regulating
exposure to magnetic fields. |
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Audience
Description:
This course is designed for individuals with at least a bachelor’s
degree in engineering and/or physical sciences, a year of research
experience with MRI and MRS at any field. Clinicians and scientists
currently working with high-field human MRI instruments or who have
recently purchased (or intend to purchase) a high field system would
find this course of interest. |
Program |
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Tuesday, 9 May |
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| 07:00 |
Impediments to
High Field MR - A Look at B0 and B1 Field Behavior |
David I Hoult,
D.Phil. |
| 07:30 |
How to Do RF at
High Fields |
J. Thomas
Vaughan, Jr., Ph.D. |
| Wednesday,
10 May |
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| 07:00 |
High Resolution
Imaging: Why Is It Important for T1 Weighted Imaging, MRA and
SWI? |
E. Mark Haacke,
Ph.D. |
| 07:30 |
Parallel Excitation: Making SENSE of High-Field Body MRI |
Yudong Zhu, Ph.D. |
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Thursday, 11 May |
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| 07:00 |
Advances in
Spectral Editing: MRS of Neurotransmitters |
Peter S. Allen,
Ph.D. |
| 07:30 |
Broadband
Decoupling at High Field: Challenges and
Solutions |
Robin A. de
Graaf, Ph.D. |
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Friday, 12 May |
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| 07:00 |
Getting BOLDer with High
Field fMRI |
Xiaoping P. Hu,
Ph.D. |
| 07:30 |
Static Magnetic Fields:
Bioeffects, Regulation and Management |
Penny Anne
Gowland, Ph.D. |
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