Time

Prog #

Measurement of the GABA/Glutamine Cycling Rate in the Human Brain Using ¹³C MRS

Fawzi Boumezbeur¹, Kitt F. Petersen², Gerald I. Shulman², Douglas L. Rothman¹, Graeme F. Mason¹

¹Magnetic Resonance Research Center, Yale University, New Haven, Connecticut, USA; ²Howard Hughes Medical Institute, Yale University, New Haven, Connecticut, USA
 

Diffusion-Weighted Spectroscopy Allows to Probe ¹³C Labeling of Glutamate Inside Distinct

Metabolic Compartments in the Monkey Brain - not available

Julien Valette¹, Myriam Chaumeil¹, Fawzi Boumezbeur¹, Gilles Bloch¹, Philippe Hantraye¹, Vincent Lebon¹, ²

¹CEA-CNRS SHFJ, Orsay, France; ²CEA-NeuroSpin, Gif-sur-Yvette, France
 

In Vivo Measurement of ¹³C Isotopic Enrichment of Brain Glycogen. Effect of Adrenergic

Stimulation on Glycogen Turnover.

Florence D. Morgenthaler¹, Sabrina Laus², Hanne Frenkel¹, Lijing Xin¹, Ruud B. van Heeswijk¹, Hongxia Lei³, Rolf Gruetter¹, ³

¹EPFL, Lausanne, Switzerland; ²University of Geneva, Geneva, Switzerland; ³University of Lausanne, Lausanne, Switzerland
 

In Vivo Determination of the Rate of Cerebral Carbonic Anhydrase Reaction

Jehoon Yang¹, Sujata Singh¹, Jun Shen¹

¹NIH, Bethesda, Maryland, USA
 

Glycogen Utilization During Hypoglycemia in the Human Brain

Gulin Oz¹, Anjali Kumar¹, Jyothi P. Rao¹, Elizabeth R. Seaquist¹

¹University of Minnesota, Minneapolis, Minnesota, USA
 

Kinetic Modeling of Hyperpolarized ¹³C₁-Pyruvate Metabolism Using Dynamic Magnetic

Resonance Spectroscopy

Matthew Luke Zierhut¹, ², Albert Pofu Chen¹, ², Robert Bok², Mark Albers¹, ², Vickie Zhang², Pieter Pels², James Tropp³, Ilwoo Park¹, ², Daniel B. Vigneron¹, ², John Kurhanewicz¹, ², Ralph Hurd³, Sarah J. Nelson¹, ², Yi-Fen Yen³

¹UCSF/UCB, San Francisco, California, USA; ²UCSF, San Francisco, California, USA; ³GE Healthcare, California, USA
 

Monitoring Prostate Cancer Progression in a Transgenic Murine Model Using 3T Hyperpolarized ¹³C MRSI

Mark J. Albers¹, ², Albert P. Chen¹, Robert Bok¹, Vickie Yi Zhang¹, Ralph E. Hurd³, Yi Fen Yen³, Matt L. Zierhut¹, ², Sarah J. Nelson¹, ², Daniel B. Vigneron¹, ², John Kurhanewicz¹, ²

¹University of California San Francisco, San Francisco, California, USA; ²UC Berkeley / UC San Francisco, San Francisco, California, USA; ³GE Healthcare - America, Menlo Park, California, USA

 

Detecting Tumor Cell Response to Therapy Using Hyperpolarized ¹³C MRS

Samuel E. Day¹, ², Ferdia A. Gallagher¹, ³, Mikko I. Kettunen, ¹⁴, Kevin M. Brindle, ¹⁴

¹University of Cambridge, Cambridge, UK; ²National Institutes of Health, Bethesda, Maryland, USA; ³Addenbrooke's Hospital, Cambridge, UK; ⁴Cancer Research UK Cambridge Research Institute, Cambridge, UK
 

In Vivo DNP-Enhanced 13C Labeled Acetate Brain Studies in a 9.4T Animal Scanner

Arnaud Comment¹, Kai Uffmann¹, Sami Jannin¹, Fiodar Kurdzesau¹, ², Ruud B. van Heeswijk¹, Hanne Frenkel¹, Patrick Hautle², J. A. Konter², Ben van den Brandt², Rolf Gruetter¹, Jacques J. van der Klink¹

¹Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland; ²Paul Scherrer Institute, Villigen, Switzerland
 

Real-Time Measurement of Substrate Uptake and Metabolism in Heart Using Dynamic Nuclear

Polarization-Magnetic Resonance (DNP-MR)

Lowri E. Cochlin¹, Marie A. Schroeder¹, George K. Radda¹, Kieran Clark¹, Damian J. Tyler¹

¹University of Oxford, Sherrington Building, Oxford, UK