Time

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Diffusion Tensor Imaging Reveals Nigrostriatal Degeneration in the 6-Hydroxydopamine Rat Model for Parkinson’s Disease

Nadja Van Camp¹, Ines Blockx¹, Marleen Verhoye¹, Veerle Baekelandt², Jan Sijbers¹, Annemie Van der Linden¹

¹University of Antwerp, Wilrijk, Antwerp, Belgium; ²University of Leuven, Leuven, Belgium

Diffusion Tensor Imaging Measures Therapeutic Effects in a Mouse Model of Niemann-Pick Type C Disease

at 23 Days of Age

Silvia Lope-Piedrafita¹, ², Chad M. Hicks¹, Robert J. Gillies¹, Robert P. Erickson¹, Theodore P. Trouard¹

¹University of Arizona, Tucson, Arizona, USA; ²Universidad Autónoma de Barcelona, Cerdanyola del Valles, Barcelona, Spain

Neurochemical Changes in the Early Stage of Huntington’s Disease Progression Studied in Transgenic

Mice Using ¹H and ³¹P NMR Spectroscopy

Ivan Tkac¹, Pierre-Gilles Henry¹, Janet M. Dubinsky¹

¹University of Minnesota, Minneapolis, Minnesota, USA

Study of Brain Metabolite Change in Amyotrophic Lateral Sclerosis Using TE-Averaged PRESS

Jing Han¹, Lin Ma²

¹Huanhu Hospital, Tianjin, People’s Republic of China; ²PLA General Hospital, Beijing, People’s Republic of China

Multimodality Voxel-Based MRI Study: Possible Tool for Disease Diagnosis and Monitoring in ALS

Don C. Bigler¹, Byeong-Yeul Lee¹, Helen E. Stephens¹, Collin M. Torok¹, J. Ryan Olson², Jianli Wang¹, Kevin R. Scott¹, Qing X. Yang¹, Zachary Simmons¹, Michael B. Smith¹

¹Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA; ²Memorial Hospital, York, Pennsylvania, USA
 

Longitudinal Changes in Amyotrophic Lateral Sclerosis Detected by Diffusion Tensor Imaging and MR Spectroscopy

Sumei Wang¹, Sanjeev Chawla¹, John H. Woo¹, Lauren B. Elman¹, Leo F. McCluskey¹, Harish Poptani¹, Elias R. Melhem¹

¹University of Pennsylvania, Philadelphia, Pennsylvania, USA
 

fMRI Reveals Altered Auditory Sensory Integration in Manifest and Premanifest Huntington’s Disease

Bettina Pfleiderer¹, Anne Habbel¹, Jürgen Audrich², Walter Heindel¹, Carsten Saft²

¹University Hospital Münster, Münster, Germany; ²University Hospital Bochum, Germany
 

Evaluation of Contrast Mechanisms in the Substantia Nigra, Red Nucleus and Adjacent Brain Stem Structures at 7T

Peter A. Wassenaar¹, Georgeta Mihai¹, Amir M. Abduljalil¹, Donald W. Chakeres¹, Michael V. Knopp¹, Petra Schmalbrock¹

¹The Ohio State University, Columbus, Ohio, USA

Brain Iron and Neuronal Integrity in Patients with Parkinson’s Disease Probed by Novel MRI Contrasts

Shalom Michaeli¹, Gulin Oz¹, Dennis J. Sorce¹, Michael Garwood¹, Kamil Ugurbil¹, Stacy Majestic, Paul Tuite

¹CMRR, University of Minnesota, Minneapolis, Minnesota, USA

High Contrast Susceptibility Weighted Imaging: Reliable Unwrapping Susceptibility Technique (RUST SWI)

Improved Visualization of Midbrain Nuclei for Deep Brain Stimulation

Geoffrey S. Young¹, Nan-kuei Chen²

¹Brigham  and Womens Hospital, Boston, Massachusetts, USA; ²Brigham and Women's Hospital, Boston, Massachusetts, USA