TRADITIONAL
POSTERS Hall 14.1 Wednesday 13:30 - 15:30
1924. High Resolution SE-fMRI in Humans at 3 and 7 T Using a Motor Task
Andreas Schäfer1, Wietske van der Zwaag1, Susan Francis1, Penny A. Gowland1, Richard W. Bowtell1 1University of Nottingham, Nottingham, UK
1925. Comparitive Evaluation of a Multi-Echo fMRI Acquisition Technique Using Parallel Imaging
Heiko Schmiedeskamp1, 2, Rexford D. Newbould2, Roland Bammer2 1ETH Zurich, Zurich, Switzerland; 2Stanford University, Stanford, California, USA
1926. Functional Changes in CSF Volume Estimated Using Spectroscopic Water T2 Decay Measurement
Stefan K. Piechnik1, John Evans1, Lizet H.A. Bary1, 2, Richard G. Wise1, 3, Peter Jezzard1 1Oxford University, Oxford, UK; 2Technische Universiteit Eindhoven, Eindhoven, Netherlands; 3Cardiff University, Cardiff, UK
1927. High-Resolution Human Functional MRI: Feasibility and Specificity at High (3T) and Ultra-High (7T) Fields
Itamar Kahn1, 2, Chris J. Wiggins2, Graham Wiggins2, Karla L. Miller3, Thomas Benner2, Bruce Fischl2, 4, Lawrence L. Wald2, Bradford L. Dickerson2, Randy L. Buckner1, 2 1Harvard University, Cambridge, Massachusetts, USA; 2MGH, Charlestown, Massachusetts, USA; 3Oxford, Oxford, UK; 4MIT, Charlestown, Massachusetts, USA
1928. Finger-Tapping Modulates Functional Synchrony in the Motor Cortex Network
Yin Xu1, Gaohong Wu1, Shi-Jiang Li1 1Medical College of Wisconsin, Milwaukee, Wisconsin, USA
1929. Using Independent Component Analysis to Measure Language Laterality
Anthony B. Waites1, Emil Johansson, 12, David F. Abbott1, Graeme D. Jackson1 1Brain Research Institute, Heidelberg West, Vic, Australia; 2University of Lund, Lund, Sweden
1930. Mapping of Task-Relevant Activation in Human Posterior Parietal Cortex for Processing Spatial and Non-Spatial Stimulus Characteristics
Dorothe A. Poggel1, 2, Dae-Shik Kim1, Joseph F. Rizzo2, 3, Louis J. Toth1 1Boston University Medical School, Boston, Massachusetts, USA; 2Boston VA Medical Center, Boston, Massachusetts, USA; 3Harvard Medical School, Boston, Massachusetts, USA
1931. Interclass Correlation Coefficient as a Measure of Drug Intervention in FMRI
Alejandro Caceres1, Daeana L. Hall1, Fernando O. Zelaya1, Steven C.R. Williams1, Mitul A. Mehta1 1Institute of Psychiatry, London, UK
1932. Probing Into Specificity of Neuronal Circuits Through fMRI Refractory Response
Yulwan Sung1, Masayuki Kamba1, Seiji Ogawa1 1Hamano Life Science Research Foundation, Tokyo, Japan
1933. Comparison of Unilateral and Bilateral Complex Finger Tapping-Related Activation in the Precentral Gyrus
Micheal D. Phillips1, Craig Israel Horenstein1, Mark J. Lowe1 1Cleveland Clinic, Cleveland, Ohio, USA
1934. Comparison of GE and SE BOLD fMRI Techniques in Temporal-Encoding Iso-Orientation Maps.
ChanHong Moon1, Hiro Fukuda1, Ping Wang1, Seong-Gi Kim1 1University of Pittsburgh, Pittsburgh, Pennsylvania, USA
1935. Investigating fMRI and fNIRS Signal with Balloon Model During Breath Hold Task
Uzay Emrah Emir1, Cengizhan Ozturk1, Ata Akin1 1Bogazici University, Istanbul, Turkey
1936. BOLD Contrast-To-Noise Ratio Across Field Strengths Under Global Stimulus
Christina Triantafyllou1, 2, Lawrence L. Wald2, Richard D. Hoge3 1MIT, Cambridge, Massachusetts, USA; 2MGH, Charlestown, Massachusetts, USA; 3Unite de Neuroimagerie fonctionelle, Montreal, QC, Canada
1937. Evidence of the BOLD Post-Undershoot Rebound
Kevin Murphy1, Jerzy Bodurka1, Peter Anthony Bandettini1 1National Institute of Mental Health, Bethesda, Maryland, USA
1938. Quantitative Comparison of Two Biophysical Models for the BOLD fMRI Signal: A Theoretical Study
Chenguang Zhao1, Hanzhang Lu1 1University of Texas Southwestern Medical Center, Dallas, Texas, USA
1939. Inferring Evoked and Baseline Cerebral Blood Flow, Volume, and Oxygen Metabolism from Dynamic BOLD and ASL Measurements
Theodore J. Huppert1, Monica S. Allen2, David A. Boas1 1Massachusetts General Hospital, Charlestown, Massachusetts, USA; 2University of Texas at Arlington, Arlington, Texas, USA
Hall 14.1 Wednesday 13:30 - 15:30
1940. A Time Efficient High Resolution Multi-Echo FLASH Sequence
Patrick Michael Heiler1, Sebastian Schmitter1, Lothar Rudi Schad1 1German Cancer Research Center, Heidelberg, Germany
1941. Triple Spiral with Asymmetric Spin Echo: A New Method for Improved BOLD fMRI in Regions of Magnetic Susceptibility Induced Field Inhomogeneity
Kimberly D. Brewer1, 2, James A. Rioux2, Ryan C.N. D'Arcy, 12, Chris V. Bowen, 12, Steven D. Beyea, 12 1Dalhousie University, Halifax, Nova Scotia, Canada; 2National Research Council of Canada, Halifax, Nova Scotia, Canada
1942. Single-Shot Z-Shimmed Sensitivity-Encoded Spiral-In/Out Imaging for fMRI
Trong-Kha Truong1, Allen W. Song1 1Duke University, Durham, North Carolina, USA
1943. Reduction of Magnetic Susceptibility Artifacts in Olfactory fMRI with SENSE-GESEPI-EPI Method
Qing X. Yang1, Erin K. Zimmerman1, Jianli Wang1, Paul J. Eslinger1, Robert Grunfeld1, Jeffery Vesek1, Mark D. Meadowcroft1, James R. Connor1, Michael B. Smith2 1Penn State University College of Medicine, Hershey, Pennsylvania, USA; 2Novartis Institutes for BioMedical Research, Inc., Cambridge, Massachusetts, USA
1944. Automatic Slice-Dependent Frequency Adjustments for SSFP fMRI
Ming-Long Wu1, 2, Teng-Yi Huang3, Pei-Hsin Wu1, Yi-Yu Shih1, Ming-Chung Chou1, 4, Hua-Shan Liu1, 4, Hsiao-Wen Chung1, 4, Cheng-Yu Chen4 1National Taiwan University, Taipei, Taiwan; 2Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; 3National Taiwan University of Science and Technology, Taipei, Taiwan; 4Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan
1945. Increasing the Sensitivity to BOLD Contrast in High Resolution fMRI Studies by Using 3D Spiral Technique
Yanle Hu1, Gary H. Glover1 1Stanford University, Stanford, California, USA
1946. 3D kSPA for High Spatial and High Temporal Resolution fMRI
Chunlei Liu1, Yanle Hu1, Jingjing Lu2, Gary H. Glover1, Michael E. Moseley1 1Stanford University, Stanford, California, USA; 2Peking Union Medical College Hospital, Beijing, People’s Republic of China
1947. Functional Neuroimaging of Inner Field-Of-Views Using FLASH with 2D-Selective RF Excitations
Wolfgang Weber-Fahr1, 2, Jürgen Finsterbusch1, 2 1University Medical Center Hamburg-Eppendorf, Hamburg, Germany; 2Neuroimage Nord, Hamburg-Kiel-Lübeck, Germany
1948. Localized Parallel Echo Volume Imaging at 1.5 T: A First Extensive fMRI Study
Cécile Rabrait1, Philippe Ciuciu1, Alejandro Ribés1, Cyril Poupon1, Patrick Le Roux2, Denis Le Bihan1, Franck Lethimonnier1 1CEA, Orsay, France; 2General Electric, Buc, France
1949. SSFP fMRI with Parallel Interleaved Multiple Frequency Acquisition
Pei-Hsin Wu1, Ming-Long Wu, Teng-Yi Huang2, Ming-Chung Chou, Hua-Shan Liu, Cheng-Yu Chen3, Hsiao-Wen Chung 1National Taiwan University, Taipei, Taiwan, Taiwan; 2National Taiwan University of Science and Technology; 3Tri-Service General Hospital,
1950. SSFP fMRI at 0.37 Mm3 Voxel Volume: Effects of Spatial Resolution on SNR and Functional Sensitivity
Ming-Long Wu1, 2, Pei-Hsin Wu1, Teng-Yi Huang3, Yi-Yu Shih1, Ming-Chung Chou1, 4, Hua-Shan Liu1, 4, Hsiao-Wen Chung1, 4, Cheng-Yu Chen4 1National Taiwan University, Taipei, Taiwan; 2Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; 3National Taiwan University of Science and Technology, Taipei, Taiwan; 4Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan
1951. A New Method of Motion-Compensated Spinal fMRI: Identifying Human Spinal Cord Function with Increased Sensitivity and Reproducibility
Chase R. Figley1, Patrick W. Stroman1 1Queen's University, Kingston, Ontario, Canada
Hall 14.1 Wednesday 13:30 - 15:30
1952. Quantitative Analysis of Brain Functional Hemodynamics with Time-Series T1 Mapping
Jung-Jiin Hsu1, Gary H. Glover1 1Stanford University, Stanford, California, USA
1953. T2 Weighted fMRI with Whole Brain Coverage at Ultra-High Fields
Johannes Ritter1, Eddie Auerbach1, Gregor Adriany1, Kamil Ugurbil1 1University of Minnesota, Minneapolis, Minnesota, USA
1954. Quantitative Relationships of Metabolic and Vascular Parameters in Brain Activation: A Multi-Modal fMRI Study
Hanzhang Lu1, Chenguang Zhao1, Kelly Lewis-Amezcua1 1University of Texas Southwestern Medical Center, Dallas, Texas, USA
1955. Dynamic Measurement of Functional Changes in Venous Cerebral Blood Volume at 3 T
Jean Jing Chen1, Gilbert Bruce Pike1 1Montreal Neurological Institute, Montreal, Quebec, Canada
1956. Quality of Single-Trial Discrimination in Simulataneous EEG/fMRI
Robin I. Goldman1, Adam D. Gerson2, Marios G. Philiastides2, David Friedman3, Truman R. Brown1, Paul Sajda2 1Columbia University, New York, New York, USA; 2Columbia University, New York, USA; 3New York State Psychiatric Institute, New York, New York, USA
1957. Acquisition Strategies to Improve the Specificity of Block-Design fMRI Studies of Overt Speech
David A. Soltysik1, James S. Hyde1 1Medical College of Wisconsin, Milwaukee, Wisconsin, USA
1958. Encoding of EEG in MR Images
Lars G. Hanson1, Arnold Skimminge1, Christian G. Hanson1 1Copenhagen University Hospital, Hvidovre, Denmark
1959. Optimized fMRI Protocol for Fear Conditioning Experiments at 3 Tesla Using Parallel Acquisition Technique
Alexander Kroll1, 2, Julia Ofer1, Christiane Hermann1, Herta Flor1, Lothar Rudi Schad2 1University of Heidelberg, Central Institute of Mental Health, Mannheim, Germany; 2German Cancer Research Center, Heidelberg, Germany
1960. Monitoring of the Consistency of Brain Activation by Using a Dynamic Analysis of T-Statistics - An Application to Conventional Mapping of the Motor Areas
Toshiharu Nakai1, Epifanio Bagarinao2, Kenichi Ohishi3, Chikako Kato4, Kayako Matsuo1 1National Center for Geriatrics and Gerontology, Ohbu, Aichi, Japan; 2National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaragi, Japan; 3Johns Hopkins School of Medicine, Baltimore, Maryland, USA; 4Toyohashi Sozo College, Toyohashi, Aichi
1961. Functional Magnetic Resonance Imaging (fMRI)-A Useful Tool for the Assessment of Hypothalamus Function?
Abdelmalek Benattayallah1, Daniel Flanagan2, Binu Krishnan2, Claire Ball3, Jonathan Fulford3, Kenneth Macleod3, Ian R. Summers1, Angela Shore3 1University of Exeter, Exeter, UK; 2Peninsula Medical School, Plymouth, UK; 3Peninsula Medical School, Exeter, UK
1962. Modelling BOLD Response in Auditory Cortex with Baloon Hemodynamic Model
Piotr Bogorodzki1, Tomasz Wolak1, Ewa Piatkowska-Janko1, Mateusz Orzechowski1, Robert Kuriata1, Henryk Skarzynski2, Wojciech Gradkowski3 1Warsaw University of Technology, Warsaw, Poland; 2Institute of Physiology and Pathology of Hearing, Warsaw, Poland; 3Warsaw University of Technology, Poland
1963. Effects of Capillary Orientation on Muscle T2/T2*: Comparison of Numerical Simulations with Empirical Data
Otto Alexander Sanchez1, Anneriet Marie Heemskerk1, Bruce Murray Damon1 1Vanderbilt University, Nashville, Tennessee, USA
1964. Clustering fMRI Data Using a Spatiotemporal Geodesic K-Means Algorithm
Richard Andrew James Masterton1, 2, David F. Abbott1, 2, Graeme D. Jackson1, 2 1Brain Research Institute, Melbourne, Victoria, Australia; 2The University of Melbourne, Melbourne, Victoria, Australia
1965. An MR-Compatible Haptic Device for fMRI Investigations of Force Control
Markus Klarhöfer1, Sven Haller2, Dominique Chapuis3, Roger Gassert4, Aidan Roche4, Klaus Scheffler1, Etienne Burdet4 1University of Basel, Basel, Switzerland; 2University Hospital Basel, Basel, Switzerland; 3Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland; 4Imperial College London, London, UK
Hall 14.1 Wednesday 13:30 - 15:30
1966. Functional Magnetic Resonance Imaging of Cortical Tissue Slices by Means of Signal Enhancement by Extravascular Water Protons (SEEP) Contrast
Patrick W. Stroman1, David Andrew1 1Queen's University, Kingston, Ontario, Canada
1967. Functional MRI of the Brainstem and Cervical Spinal Cord of Children Based on SEEP Contrast
Patrick W. Stroman1, Jane Lawrence2, Jennifer Kornelsen2 1Queen's University, Kingston, Ontario, Canada; 2Stanford University, Palo Alto, California, USA
1968. Functional Contrast Based on iDQC - Influence of the Correlation Distance
Andreas Schäfer1, 2, Harald E. Möller2 1University of Nottingham, Nottingham, UK; 2Max Planck Institute for Human Cognitive and Brain Science, Leipzig, Germany
1969. Hypercapnia-Induced Vasoreactivity as Evaluated by Vascular-Space-Occupancy (VASO) Dependent fMRI
Hanzhang Lu1, Uma Yezhuvath1, Kelly Lewis-Amezcua1, Jinsoo Uh1, Feng Xu1, Rani Varghese1 1University of Texas Southwestern Medical Center, Dallas, Texas, USA
1970. Direct Comparison of Multi-Echo BOLD and VASO Based fMRI
Erik Groenewold1, Hans Hoogduin2 1University Medical Center Groningen, University of Groningen; 2University Medical Center Groningen, University of Groningen, Groningen, Netherlands
1971. Single-Shot ADC Imaging for fMRI
Allen W. Song1, Hua Guo1, Trong-Kha Truong1 1Duke University, Durham, North Carolina, USA
1972. Direct Detection of Neuronal Magnetic Field Changes Using MRI:Timing Effect of Stimulation
Yiqun Xue1, Xiying Chen1, Thomas Grabowski1, Jinhu Xiong1 1University of Iowa, Iowa city, Iowa, USA
1973. Improved Temporal Resolution in Time-Series ASL Perfusion Imaging with Single-Shot 3D GRASE Using Variable Shared Control Phases
David A. Feinberg1, 2, Sudhir Ramanna1 1Advanced MRI Technologies and Redwood Regional Medical Group, Sebastopol, California, USA; 2CIND, VA Medical Center, San Francisco, California, USA
1974. Lorentz Effect Imaging of Ionic Currents in Solution
Trong-Kha Truong1, Alexandru Avram1, Allen W. Song1 1Duke University, Durham, North Carolina, USA
1975. Functional 31P-{1H} EPSI with 6 S Temporal Resolution of the Human Brain
Marco Ulrich1, Tim Wokrina1, Nuran Tunc-Skarka1, Peter Bachert2, Gabriele Ende1 1Central Institute of Mental Health, Mannheim, Germany; 2German Cancer Research Center, Heidelberg, Germany
Hall 14.1 Wednesday 13:30 - 15:30
1976. EPI Magnitude Signal Formation in the Proximity of Straight Conductor Subjected to a Weak Electric Current.
Jerzy Bodurka1, Peter Bandettini1 1National Institute of Mental Health, NIH, Bethesda, Maryland, USA
1977. Reducing Correlated Noise in fMRI Data
Jacco A. de Zwart1, Peter van Gelderen1, Masaki Fukunaga1, Jeff H. Duyn1 1National Institutes of Health, Bethesda, Maryland, USA
1978. Reducing Effects of Drift in fMRI Data Using Joint Reconstruction of R2* and Field Maps
Valur Olafsson1, Magnus Ulfarsson1, Jeffrey A. Fessler1, Douglas C. Noll1 1University of Michigan, Ann Arbor, Michigan, USA
1979. Determination of Inversely Correlated Resting State Brain Functional Networks Using Cluster Analysis
Cheuk Ying Tang1, Eric Leung1, David Carpenter1, Johnny Ng1 1Mount Sinai School of Medicine, New York, New York, USA
1980. Resting-State Functional Connectivity and Stimulation-Induced Neural Activity in the Cortex and Sub-Cortical Structures of Rat Brain
Fuqiang Zhao1, Tiejun Zhao1, Lei Zhou1, Qiulin Wu1, Zhi Yang1, Xiaoping Hu1 1Emory / Georgia Tech, Atlanta, Georgia, USA
1981. Extracting the Resting-State BOLD Signal from an Event-Related fMRI Study
Minjie Wu1, Robert Tamburo1, Greg Siegle1, Howard J. Aizenstein1 1University of Pittsburgh, Pittsburgh, Pennsylvania, USA
1982. MR Signal Fluctuations and Regional Vasomotion
Homer Pien1, Wei-Ting Zhang1, Emmanuelle DiTomaso1, D. G. Duda2, Rakesh Jain1, Tracy Batchelor1, A. Gregory Sorensen1 1Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA; 2Massachusetts General Hospital and Harvard Medical School, Bosotn, Massachusetts, USA
1983. Mitigation of Physiological Noise in the fMRI Time-Series by CSF Nulling
Christina Triantafyllou1, 2, Lawrence L. Wald2 1MIT, Cambridge, Massachusetts, USA; 2MGH, Charlestown, Massachusetts, USA
1984. Characterization of an Intrinsic Low-Frequency Component at Around 0.025 Hz in Steady-State fMRI Signals
Yin Xu1, Guofan Xu1, Gaohong Wu1, Shi-Jiang Li1 1Medical College of Wisconsin, Milwaukee, Wisconsin, USA
1985. Connectivity Analysis During Motor Imagery and Motor Execution Using DCM
Christian H. Kasess1, Ross Cunnington2, Rupert Lanzenberger1, Ewald Moser1, Lukas Pezawas1, Christian Windischberger1 1Medical University of Vienna, Vienna, Austria; 2University of Melbourne, Melbourne, Australia
1986. Low-Frequency Fluctuations in the Cardiac Rate Contribute to Variance in the Resting-State fMRI BOLD Signal
Karin Shmueli1, Peter van Gelderen1, Jacco A. de Zwart1, Silvina G. Horovitz1, Masaki Fukunaga1, J Martijn Jansma1, Jeff H. Duyn1 1National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
1987. Group Independent Component Analysis Reveals Consistent Resting-State Networks Across Multiple Sessions
Sharon Chen1, Yihong Yang1, Wang Zhan1, Elliot A. Stein1, Carol S. Myers1, Stephen J. Heishman1, Keh-Shih Chuang2, Thomas J. Ross1 1National Institute on Drug Abuse, Baltimore, Maryland, USA; 2National Tsing-Hua University, Hsin Chu, Taiwan
1988. Structural Equation Modeling of Resting-State Temporal Lobe Functional Connectivity
George Andrew James1, Stephen M. LaConte1, Richard Cameron Craddock1, Thomas Reid Henry2, Helen S. Mayberg2, Xiaoping P. Hu1 1Emory University and Georgia Institute of Technology, Atlanta, Georgia, USA; 2Emory University, Atlanta, Georgia, USA
1989. Functional Hierarchy of the Visual System as Revealed by Resting-State Connectivity
Egbert Jan Willem Bleeker1, Hubert M.J. Fonteijn2, Elena Shumskaya2, Jens Schwarzbach3, David G. Norris2 1Leiden University Medical Center, Leiden, Netherlands; 2F.C. Donders Centre for Cognitive Neuroimaging, Nijmegen, Netherlands; 3University of Trento, Trento, Italy
fMRI: Miscellaneous Neuro Applications Hall 14.1 Wednesday 13:30 - 15:30
1990. Cortical Activation in Reduced During Motor Imagery in Amyotrophic Lateral Sclerosis
Biba Rhiannon Stanton1, Victoria C. Williams1, Peter Nigel Leigh1, Steven Williams1, Andrew Simmons1 1Institute of Psychiatry, King's College London, London, UK
1991. Hypothalamic Functional MRI Response After Glucose Ingestion Is Diminished in Patients with Type 2 Diabetes Mellitus
Paul Smeets1, Solrun Vidarsdottir2, Matthias van Osch2, Max Viergever1, Diana Eichelsheim2, Johannes Romijn2, Hanno Pijl2, Jeroen van der Grond2 1University Medical Center Utrecht, Utrecht, Netherlands; 2Leiden University Medical Center, Netherlands
1992. Brain fMRI Correlates of Pain in Diabetes
Iain D. Wilkinson1, Rajiv A. Gandhi2, Dinesh Selvarajah2, Michael D. Hunter1, Celia J. Emery2, Paul D. Griffiths1, Solomon Tesfaye2 1University of Sheffield, Sheffield, UK; 2Royal Hallamshire Hospital, Sheffield, UK
1993. A Network Analysis of Acupuncture Effects by Functional Connectivity MRI
Lin Yang1, Wei Qin2, Xiulai Gao1, Jie Tian2, Peng Chen3, Jianping Dai4, Hongyan Chen4 1Department of Anatomy and Embryology,China Capital Medical University, Beijing, People’s Republic of China; 2Medical Image Processing Group, Institute of Automation, Chinese Academy of Sciences, Beijing, People’s Republic of China; 3Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 4Department of Radiology, Beijing Tiantan Hospital£Capital University of Medical Sciences, Beijing, People’s Republic of China
1994. Brain Activation in Overactive Bladder Patients Evaluated by Pharmacological fMRI
Shweta Moonat1, Michael Pontari1, Steve Lebovitch1, Brett Lebed1, Michael Ruggieri1, Scott H. Faro1, Feroze B. Mohamed1 1Temple University, Philadelphia, Pennsylvania, USA
1995. BOLD fMRI Response in the Motor Cortex Is Strongly Linked with CO2 Reactivity in Patients with Carotid Artery Disease.
Stephen David Goode1, Christine Ojango1, Dorothee Auer1 1Queens Medical Centre, Nottingham, UK
1996. Characterization of Cortical Activation Patterns in Action Induced Focal Dystonia by 3.0 T fMRI
Karl Titus Hoffmann1, Tina Islam1, Harald Bruhn1, Sein Schmidt2, Lutz Lüdemann1, Thomas Trottenberg2, Andreas Kupsch2 1Charité Virchow, Berlin, Germany; 2Charité,
1997. fMRI of Brain Activity During Active Place Avoidance in a Task of Divided Attention
Martin Meier1, 2, Peter Ehrhard2, Andre A. Fenton3, Kamil Vlcek3, Barbara Wolynski1, Dieter Leibfritz2 1University of Magdeburg, Magdeburg, Germany; 2University of Bremen, Bremen, Germany; 3Academy of Science of the Czech Republic, Prague
1998. Analyzing Structural and Functional Imaging Data on the Cortical Surface
Donald G. McLaren1, Adrian A. Epstein2, Josh S. Shimony2, Harold Burton2, David C. Van Essen2, Andy L. Alexander1, Sterling C. Johnson1 1University of Wisconsin, Madison, Wisconsin, USA; 2Washington University School of Medicine, St. Louis, Missouri, USA
Hall 14.1 Wednesday 13:30 - 15:30
1999. Networks of Correlated Activity in the phMRI Response to Amphetamine Resolved by Cluster Analysis
Adam James Schwarz1, Alessandro Gozzi1, Torsten Reese1, Angelo Bifone1 1GlaxoSmithKline / Psychiatry CEDD, Verona, Veneto, Italy
2000. Neural Substrates of the Orexigenic Hormone Ghrelin: A Pharmacological MRI Study in the Rat
Alessandro Gozzi1, Adam Schwarz1, Valerio Crestan1, Carla Di Francesco1, Francesca Marini1, Mario Massagrande1, Torsten Reese1, Phil Gerrard1, Christian Heidbreder1, Sergio Melotto1, Angelo Bifone1 1Centre of Excellence for Drug Discovery, Psychiatry, GlaxoSmithKline Medicines Research Centre, Verona, Italy
2001. Drug-Anaesthetic Interaction in Pharmacological MRI: The Case of the Psychotogenic Agent Phencyclidine
Alessandro Gozzi1, Adam Schwarz1, Torsten Reese1, Valerio Crestan1, Angelo Bifone1 1Centre of Excellence for Drug Discovery, Psychiatry, GlaxoSmithKline Medicines Research Centre, Verona, Italy
2002. Assessment of Ocular Dominance Plasticity with Functional MRI at 3 Tesla
Jeffrey Keating Thompson1, Louis J. Toth1, Itamar Ronen1, Dae-Shik Kim1 1Boston University School of Medicine, Boston, Massachusetts, USA
2003. Coupling Between Simultaneously Recorded BOLD Response and Neuronal Activity in the Rat Somatosensory Cortex Under Different Anesthetics
Joanna K. Huttunen1, Olli Gröhn1, Markku Penttonen1, 2 1University of Kuopio, Kuopio, Finland; 2University of Jyväskylä, Jyväskylä, Finland
2004. Amphetamine PharmacoMRI in the Rat Under Isoflurane Anesthesia
Carmen de Groote1, Shane McKie1, Bill Deakin1, Steve Ross Williams1 1University of Manchester, Manchester, Greater Manchester, UK
2005. Characterizing the Differential Effects of Selective Cannabinoid Agonists on Brain Activity in Awake Rats Using Pharmacological MRI
Chih-Liang Chin1, Terese R. Seifert1, Ann E. Tovcimak1, Vincent P. Hradil1, Michael J. Dart1, Gin C. Hsieh1, Michael D. Meyer1, Betty B. Yao1, Bryan F. Cox1, Gerard b. Fox1 1Abbott Laboratories, Abbott Park, Illinois, USA
2006. Activity Mappings in Olfactory Bulb of Newborn Rabbits Elicited by Odor Stimulation Using Quantitative Manganese Enhanced MRI
Jean-marie Bonny1, Gilles Sicard2, Yves Maurin3, Cécile Keller1, Benoist Schaal2, Olivier Rampin3, Jean-Pierre Renou1, André Holley2, Philippe Andrey3, Gérard Coureaud2 1INRA, Saint-Genès Champanelle, France; 2CNRS, Dijon, France; 3INRA, Jouy en josas, France
2007. Selective Modulation of Functional Connectivity in the Brain’s Reward Pathway by D3 Receptor Antagonism
Adam James Schwarz1, Alessandro Gozzi1, Torsten Reese1, Christian A. Heidbreder1, Angelo Bifone1 1GlaxoSmithKline / Psychiatry CEDD, Verona, Veneto, Italy
2008. Modeling Dopamine Dynamics Using Combined Microdialysis and MRI Measurements.
Bruce G. Jenkins1, Ji-Kyung Choi1, Andac Hamamci1, Joseph B. Mandeville1, Bruce R. Rosen1, Yin-Ching Iris Chen1 1Massachusetts General Hospital, Charlestown, Massachusetts, USA
2009. Investigating the Influence of Anesthesia on Resting State Connectivity in Rats Using Multiple Analysis Techniques
Kathleen A. Williams1, Stephen M. LaConte1, Scott J. Peltier2, Shella D. Keilholz1 1Georgia Institute of Technology/Emory University, Atlanta, Georgia, USA; 2University of Michigan, Ann Arbor, Michigan, USA
2010. Rat BOLD fMRI Using Domitor for Anesthesia: Investigation of Stimulus Dependence and Negative BOLD Response in Somatosensory Network
Fuqiang Zhao1, Tiejun Zhao1, Lei Zhou1, Qiulin Wu1, Xiaoping Hu1 1Emory / Georgia Tech, Atlanta, Georgia, USA
2011. In Vivo Mapping of Functional Connectivity in Active Neurotransmitter Systems Using Pharmacological MRI
Adam James Schwarz1, Alessandro Gozzi1, Torsten Reese1, Angelo Bifone1 1GlaxoSmithKline / Psychiatry CEDD, Verona, Veneto, Italy
2012. Quantification of Resting State CMRO2 Using Low-Frequency Hemodynamic Oscillations in Rat Brains
Young R. Kim1, Bharat B. Biswal2, Bruce R. Rosen1 1Athinoula Martinos Center for Biomedical Imaging/Massachusetts General Hospital, Charlestown, Massachusetts, USA; 2UMDNJ-New Jersey Medical School/ Department of Radiology, Newark, New Jersey, USA
2013. Towards Functional MRI in Blood Free Rats
Helen E. D'Arceuil1, Richard M. Kiral2, Alex J. de Crespigny1 1Massachusetts General Hospital, Charlestown, Massachusetts, USA; 2Synthetic Blood International Inc., Costa Mesa, California, USA
2014. Analysis of Amphetamine-Induced BOLD fMRI Signals in Striatum Indicate Novel Temporal Regulation by Insulin
Jason M. Williams1, John C. Gore1, Malcolm J. Avison1, Aurelio Galli1 1Vanderbilt University Medical Center, Nashville, Tennessee, USA
2015. Spin-Echo fMRI of the Temporal Lobe in Awake, Behaving Monkeys at 7T
Jozien B.M. Goense1, Shih-Pi Ku1, Hellmut Merkle2, Andreas S. Tolias1, 3, Nikos K. Logothetis1 1Max-Planck Institute for Biological Cybernetics, Tübingen, Germany; 2NIH/NINDS, Bethesda, Maryland, USA; 3Baylor College of Medicine, Houston, Texas, USA
2016. Functional MRI of Spontaneous Absence Seizures in a Genetic Rat Model
Olivier David1, Isabelle Guillemain2, Sébastien Reyt3, Colin Deransart2, Christoph Segebarth3, Antoine Depaulis2 1UM UJF-Inserm 594, Grenoble, France; 2UM UJF-Inserm 704, France; 3UM UJF-Inserm 594, France
2017. Functional MRI in a Zebra Finch Model of Dysfluency Shows Altered BOLD Responses to Familiar Birdsong Stimuli
Henning U. Voss1, Delanthi Salgado-Commissariat2, Douglas Ballon1, Santosh A. Helekar2 1Cornell Medical College, New York, New York, USA; 2The Methodist Neurological Institute, Houston, Texas, USA
2018. Do Differences in BOLD and CBV Responses to Cortical Stimulation During mGluR5 Blockade Reflect Regional Differences in Neurovascular Coupling Mechanisms?
Hazel Sloan1, Vivienne Austin1, Andrew Lowe1, Michael O'Neill2, Paul Matthews3, Nicola Sibson1 1University of Oxford, Oxford, UK; 2Eli Lilly & Co. Ltd, UK; 3GlaxoSmithKline, UK
2019. Dynamic Response of the Livers of Chronic Ethanol-Treated Rats to Oxygenation Changes: An fMRI Study
Manfred Brauer1, Melissa J. Yau2, Lesley M. Foley3 1University of Guelph, Guelph, Ontario, Canada; 2University of Guelph, Guelph, Canada; 3Carnegie Mellon University, Pittsburgh, Pennsylvania, USA
2020. Role of Glutamate Release in Ketamine-Induced Blood-Oxygenation Level Dependent (BOLD) Responses: An fMRI Study in Rats.
Carmen de Groote1, Shane McKie1, Bill Deakin1, Steve Ross Williams1 1University of Manchester, Manchester, UK
2021. Functional Brain Mapping During Acute Stimulation Through Chronic Electrode Implants in Rat
Jeff F. Dunn1, Ursula I. Tuor, 12, Jonn Kmech1, Nicole A. Young1, G Campbell Teskey1, Pamela A. Valentine1 1University of Calgary, Calgary, AB, Canada; 2National Research Council, Calgary, AB, Canada
fMRI Applications: Neuroscience Hall 14.1 Wednesday 13:30 - 14:30
2022. The Neural Correlates of Interpreting Speech-In-Noise in Children with Unilateral Sensorineural Hearing Loss Investigated Using a Functional MRI Paradigm with Silent Gradient Intervals
Vincent J. Schmithorst1, Robert W. Keith2, David Brown1, Scott K. Holland1 1Children's Hospital Medical Center, Cincinnati, Ohio, USA; 2University of Cincinnati, Cincinnati, Ohio, USA
2023. Congruence Between BOLD Activation Pattern and the Maximal Suppression Effect by TMS During a Simple Visual Discrimination Task
Axel Thielscher1, Alexandra Reichenbach1, Kamil Ugurbil1, 2, Kamil Uludag1 1MPI for biological Cybernetics, Tübingen, BW, Germany; 2University of Minnesota, Minneapolis, Minnesota, USA
2024. Multisensory Recruitment Associated with REM Sleep Eye Movements: An fMRI Study
Charles Chong-Hwa Hong1, James C. Harris2, Godfrey D. Pearlson3, 4, Jin-Suh Kim5, Vince D. Calhoun6, 7, James H. Fallon8, Xavier Golay9, Joseph S. Gillen, 210, Peter C.M. van Zijl, 210, David S. Zee2, James J. Pekar, 210 1Johns Hopkins University, Baltimore, Maryland; 2Johns Hopkins University, Baltimore, Maryland, USA; 3Yale University, New Haven, Connecticut, USA; 4Hartford Hospital, Hartford, Connecticut, USA; 5University of Iowa, Iowa City, Iowa, USA; 6University of New Mexico, Albuquerque, New Mexico; 7The MIND Institute, Albuquerque, New Mexico, USA; 8University of California, Irvine, Irvine, California, USA; 9Singapore Bioimaging Consortium, Singapore, Singapore; 10Kennedy Krieger Institute, Baltimore, Maryland, USA
2025. Relating Yourself to Visual Scenes Incongruous with Body Posture: An fMRI Study
Kayako Matsuo1, Epifanio Tila Bagarinao, Jr. 2, Chikako Kato3, Toshiharu Nakai1 1National Center for Geriatrics and Gerontology, Obu, Aichi, Japan; 2National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan; 3Toyohashi Sozo University, Toyohashi, Aichi, Japan
2026. Comparing Functional Connectivity in Default Mode of Brain Between Adult and Children During Mental Calculation
Feiyan Chen1, Lixia Tian2, Hongjian He1, Weimin Zhang1, Zhikang Wang1, Tianzi Jiang2 1Zhejiang University, Hangzhou, Zhejiang, People’s Republic of China; 2Institute of Automation, Chinese Academy of Sciences, Beijing, People’s Republic of China
2027. Neural Correlates of Attentional Control of Conflict Processing: fMRI Evidence from a Stroop Match-To-Sample Task
Tilman Schulte1, Eva Maria Muller-Oehring2, Dirk Mayer3, Shara Vinco1, Adolf Pfefferbaum1, Edith V. Sullivan2 1SRI International, Menlo Park, California, USA; 2Stanford University, Stanford, California, USA; 3Stanford University, Stanford, USA
2028. Effects of Citalopram on Effective Connectivity During the Go/No-Go Task
Nia Goulden1, Shane McKie1, Rebecca Elliott1, Steve Williams1, Cristina Del-Ben2, John Frances William Deakin1, Ian Anderson1 1University of Manchester, Manchester, UK; 2University of Sao Paulo, Ribeirao Presto, Brazil
2029. Teasing Apart the Paced Auditory Serial Addition Task (PASAT): An fMRI Study
Shen-Hsing Annabel Chen1, Jessie Shuo-En Huang1, Jill Dorflinger2, Judi Zaferos2, Sally Durgerian2, Stephen M. Rao2 1National Taiwan University, Taipei, Taiwan; 2Medical College of Wisconsin, Milwaukee, Wisconsin, USA
2030. Joint Activation of the SMA and Pre-SMA During Simultaneous Motor and Language Tasks: A Functional MRI Study
Kyung Peck1, Bob Hou1, Estee Psaty2, Michelle Bradbury3, Nicole Petrovich3, Andrei Holodny4 1Memorial Sloan-Kettering Cancer Center, New York, USA; 2Albert Einstein College of Medicine, New York; 3Memorial Sloan-Kettering Cancer Center, New York; 4Memorial Sloan-Kettering Cancer Center, New York, USA
2031. Can High Field Functional MRI Detect Interhemispheric Transfer of Visual and Motor Information?
Erin Lindsay Mazerolle1, 2, Ryan C N D'Arcy, 12, Chris V. Bowen, 12, Steven D. Beyea, 12 1Dalhousie University, Halifax, Nova Scotia, Canada; 2National Research Council, Halifax, Nova Scotia, Canada
2032. Neural Correlates of Cross Script Repetition Priming: An fMRI Study
Hyo Woon Yoon1, Kyungduk Cho2, Jun-Young Chung3, HyunWook Park 1Gachon University of Medicine and Science, Incheon, Republic of Korea; 2Paichai University, Daejeon, Republic of Korea; 3KAIST, Daejeon, Republic of Korea
2033. Motor Representations of Well-Practiced Handwriting Versus Novel Motor Sequences of Graphomoto Output: An fMRI Study
Meirav Balas1, 2, David Manor3, Nir Giladi2, 4, Tammar Kushnir3, Avi Karni, 13 1Haifa University, Haifa, Israel; 2Tel-Aviv Sourasky Medical Center, Tel Aviv, Israel; 3The Chaim Sheba Medical Center, Tel Hashomer, Israel; 4Tel Aviv University, Tel Aviv, Israel
2034. Does the Modulation of the Insular Activity Affect Our Emotional Involvement? A Real-Time fMRI Study During Emotional Pictures Processing
Andrea Caria1, Ranganatha Sitaram1, Ralf Veit1, 2, Niels Birbaumer1, 3 1University of Tübingen, Tübingen, Germany; 2Max Planck Institute for Biological Cybernetics, Tübingen, Germany; 3National Institute of Health (NIH), Bethesda, USA
2035. Meta-Analysis of fMRI Activation Associated with Response Inhibition During Performance of Go/Nogo Tasks
Daniel Joseph Simmonds1, James J. Pekar1, 2, Stewart H. Mostofsky1, 2 1Kennedy Krieger Institute, Baltimore, Maryland, USA; 2Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
2036. Cervical Spinal fMRI Study: Modulation of Functional Activation Signal by Task Difficulty, Hand Skill and Handedness
Man Cheuk Ng1, Ho Fai Lau1, E X. Wu1, E S. Yang2, y Hu2, D K. Luk2 1The University of Hong Kong, Pokfulam, Hong Kong; 2The University of Hong Kong, Pokfulam, Hong Kong
2037. Cognitive Coping Style Modulates Neural Responses to Emotional Faces – a 3T fMRI Study
Harald Kugel1, Astrid Veronika Rauch1, Patricia Ohrmann1, Jochen Bauer1, Almut Engelien1, Volker Arolt1, Walter Heindel1, Thomas Suslow1 1University of Muenster, Muenster, NRW, Germany
2038. Dissociating Bottom-Up Responses in the Amygdala from Top-Down Processing in the Orbitofrontal Cortex Using an Event-Related Emotion Rating Paradigm
Paul Wright1, Dolores Albarracin1, Rick Donald Brown1, Hong Li1, G He1, Yijun Liu1 1University of Florida, Gainesville, Florida, USA
2039. Administration of Selective Serotonin Reuptake Inhibitors Changes Amygdala Activation During Facial Emotion Processing
Christian Windischberger1, Rupert Lanzenberger1, Susanne Friedreich1, Christoph Spindelegger1, Alexander Holik1, Patrycja Stein1, Ulrike Moser1, Ewald Moser1, Siegfried Kasper1 1Medical University of Vienna, Vienna, Austria
2040. Functional Brain Correlates of Response Time Variability in Children
Daniel Joseph Simmonds1, Sunaina G. Fotedar1, Stacy J. Suskauer1, 2, James J. Pekar1, 2, Martha B. Denckla1, 2, Stewart H. Mostofsky1, 2 1Kennedy Krieger Institute, Baltimore, Maryland, USA; 2Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
2041. Learning Effects of Neurofeedback-fMRI on Neural Substrates Involved in Motor Imagery
Seung-Schik Yoo1, Jong-Hwan Lee1, Matthew Marzelli2, Ferenc A. Jolesz3, Lawrence P. Panych1 1Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA; 2Boston University, Boston, Massachusetts, USA; 3Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA
2042. Assessing the Influence of Negative Mood on Brain Processing of Visceral Sensation
Steven John Coen1, Martina Mitterschiffthaler1, Lloyd J. Gregory2, Lidia Yágüez1, Michael J. Brammer1, Steven CR Williams1, Qasim Aziz2 1Institute of Psychiatry, Kings College, London, UK; 2University of Manchester, UK
2043. Resting in Peace, Noise or with Instructions: The Influence of Scanner Background Noise on the Default Mode of Brain Functions
Nadine Gaab1, Noa Ofen1, John DE Gabrieli1, Gary H. Glover2 1MIT, Cambridge, Massachusetts, USA; 2Stanford University, Stanford, California, USA
2044. Ingested Lipid Modulates Hypothalamic and Brainstem Neuronal Activity in Man: A phMRI Study
Shane McKie1, Daniel J. Lassman2, Lloyd J. Gregory2, Graham J. Dockray3, David G. Thompson2 1University of Manchester, Manchester, UK; 2Hope Hospital, Salford, UK; 3University of Liverpool, Liverpool, UK
2045. Altered Basal Ganglia Activation During Complex Finger Tapping Tasks in Patients with MS
Micheal D. Phillips1, Craig Israel Horenstein1, Lael Stone1, Ruth Ann Marrie1, Mark J. Lowe1 1Cleveland Clinic, Cleveland, Ohio, USA
2046. FMRI Reveals that Peak Activated Regions in the Primary Sensorimotor Cortex and Premotor Regions are the Same for Multiple Sclerosis Patients and Controls During Complex Finger Tapping
Micheal D. Phillips1, Craig Israel Horenstein1, Lael Stone1, Ruth Ann Marrie1, Mark J. Lowe1 1Cleveland Clinic, Cleveland, Ohio, USA
2047. Measuring Variability in the BOLD Response to Interictal Epileptiform Discharges: An EEG/fMRI Study
Anthony B. Waites1, Danny Flanagan1, Richard A. Masterton1, David F. Abbott1, Graeme D. Jackson1 1Brain Research Institute, Heidelberg West, Vic, Australia
2048. Modelling Large Head Motion Events in fMRI Studies of Patients with Epilepsy
Louis Lemieux1, Afraim Salek-addadi1, Torben Ellegaard Lund2, Helmut Laufs1, David Carmichael1, Roman Rodionov1 1Institute of Neurology, University College London, London, UK; 2Danish Research Centre for MR, Denmark
2049. Identification of a Multivariate Biomarker of Alzheimer's Disease with ASL
Christian Habeck1, Iris Asllani1, Ajna Borogovac1, Nikolaos Scarmeas1, Truman Brown1, Yaakov Stern1 1Columbia University, New York, USA
2050. Limited Default Network in Bipolar Disorder by BOLD-Based fMRI
Sue-jin Lin1, Tzu-chen Yeh, 12, Chou-Ming Cheng2, Wen-Jui Kuo1, Jen-chuen Hsieh1, 2, Ton-ping Su, 12, Low-tone Ho, 12 1National Yang-Ming University, Taipei, Taiwan, Taiwan; 2Taipei Veterans General Hospital, Taipei, Taiwan, Taiwan
2051. Therapeutic Effect of Intensive Sensory Motor Integration Training in Children with ADHD: A Multimodal Approach Using fMRI and VBM
Chien han Lai1, Tzu-chen Yeh, 12, Chou-ming Cheng2, Ming-hwei Yen3, Shin-Siung Jung4 1National Yang-Ming University, Taipei, Taiwan, Taiwan; 2Taipei Veterans General Hospital, Taipei, Taiwan, Taiwan; 3BioInno Health Technology, Taipei, Taiwan, Taiwan; 4Taiwan Research Institute of Learning Disability, Taipei, Taiwan, Taiwan
2052. Test-Retest Reproducibility of Cerebral and Subjective Responses to Painful and Non-Painful Contact-Heat Evoked Potential Stimulation (CHEPS)
Matt A. Howard1, Steven J. Coen1, Tim J. Buchanan2, Trevor S. Smart2, Sarah L. Gregory1, John P. Huggins2, Magdi Hanna3, William Vennart2, Steven C R Williams1 1Institute of Psychiatry, London, UK; 2Pfizer, Sandwich, UK; 3Kings College Hospital, London, UK
Hall 14.1 Wednesday 13:30 - 15:30
2053. Tripping Over Ourselves to Image the Cerebellum
Sean CL Deoni1, 2, Marco Catani2 1Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, Oxford, England, UK; 2Institute of Psychiatry, London, England, UK
2054. Detection of the Stria of Gennari Using Turbo Spin Echo Imaging at High Field
Rosa Maria Sanchez Panchuelo1, Stuart Clare2, Holly Bridge2, Richard Bowtell1, Sue Francis1 1University of Nottingham, Nottingham, UK; 2University of Oxford, Oxford, UK
2055. Signal Intensity of the Motor Cortex on Phase-Weighted Images at 3T
Mai Hanamiya1, Shingo Kakeda1, Junji Moriya1, Norihiro Ohnari1, Toru Sato1, Mika Kitajima2, Haque Hasnine3, Naoki Hirata3, Yukunori Korogi1 1University of Occupational and Environmental Health School of Medicine, Kitakyushu, Fukuoka, Japan; 2Department of Radiology, Kumamoto University School of Medicine; 3GE Yokogawa Medical Systems, Ltd,
2056. Sex Differences in the Mid-Sagittal Area of Corpus Callosum in the Human Brain Image Obtained at 4.7T
Nobuhiro Takaya1, Hidehiro Watanabe1, Fumiyuki Mitsumori1 1National Institute for Environmental Studies, Tsukuba, Ibaraki, Japan
2057. Age-Related Changes of Normal Subthalamic Nucleus: Evaluation with High Resolution MR Imaging at 3.0 T
Mika Kitajima1, Shingo Kakeda2, Junji Moriya2, Norihiro Ohnari2, Toru Sato2, Yoshiko Hayashida1, Toshinori Hirai1, Yasuyuki Yamashita1, Mitsuhiro Uike3, Yukunori Korogi2 1Kumamoto University, Kumamoto, Japan; 2University of Occupational and Environmental, Kitakyushu, Japan; 3GE Yokogawa Medial Systems, Japan
2058. Optimized High-Resolution Mapping of Magnetisation Transfer at 3 Tesla Reveals Substructures in the Human Thalamus in Clinically Feasible Measurement Time
Gunther Helms1, Tabea Gringel1, Erck Elolf1, Walter Schulz-Schaeffer2, Peter Dechent1 1University of Göttingen, Faculty of Medicine, Göttingen, Germany; 2University of Göttingen, Faculty of Medicine, Germany
2059. Thalamo-Cortical Abnormalities Correlate with Thalamic Atrophy in CIS Patients at Presentation
Mason Shieh1, Daniel Pelletier1, SungWon Chung1, 2, Darin Okuda1, Roland G. Henry1, 2 1University of California at San Francisco, San Francisco, California, USA; 2University of California at Berkeley, Berkeley, California, USA
2060. Now That’s a Hippo! a Clinical Imaging Protocol for the Human Hippocampus at 7T
Jens Matthias Theysohn1, 2, Oliver Kraff1, 2, Stefan Maderwald1, 2, Armin de Greiff1, 2, Mark E. Ladd1, 2, Susanne C. Ladd1, 2, Elke Ruth Gizewski2, Michael Forsting2 1University Duisburg-Essen, Essen, Germany; 2University Hospital Essen, Essen, Germany
2061. Hippocampal Atrophy is the Critical Brain Change in Patients with Memory Disorder Resulting from Anoxic Episode
Margherita Di Paola1, Lucia Fadda2, Laura Serra, Carlo Caltagirone2, Giovanni Augusto Carlesimo2 1Neuroimaging Laboratory, IRCCS S. Lucia Foundation, Rome, Italy, Italy; 2Department of Neurological Sciences, University of Rome “Tor Vergata”, Rome, Italy
2062. Quantitative Brain Tissue Mapping Using Fast Spin Echo Imaging
Robert Marc Lebel1, Luis Concha1, Christian Beaulieu1, Alan H. Wilman1 1University of Alberta, Edmonton, Alberta, Canada
2063. One Third of the Anterior Portion of the Optic Nerve Is Susceptible to Motion of Different Eye Direction
Michael G. Dwyer1, David A. Fritz1, Jennifer L. Cox1, Sonal Ambwani1, Erik Saluste2, Robert Matyas2, Robert Zivadinov1 1Buffalo Neuroimaging Analysis Center, Buffalo, New York, USA; 2Buffalo General Hospital, Buffalo, New York, USA
2064. Segmentation of Subtraction Images Yields Improvement in Reproducibility and Sensitivity of Lesion Change Measurements in MS
Yang Duan1, 2, David F. Tate3, 4, Peter G. Hildenbrand3, 5, Istvan Csapo3, Dominik S. Meier3, Charles R.G. Guttmann3 1Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; 2The Second Clinical College & The Second Affiliated Hospital, China Medical University, Shenyang, Liaoning, People’s Republic of China; 3Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; 4Brown Medical School, Providence, Rhode Island, USA; 5Lahey Clinic, Burlington, Massachusetts, USA
2065. MR Imaging of a Postmortem Formalin-Fixed Human Brain of a Multiple Sclerosis Patient at 3T and 7T
Steffen Sammet1, Alayar Kangarlu2, Eric Bourekas1, Kottil W. Rammohan1, Regina Maria Koch1, Michael V. Knopp1 1The Ohio State University, Columbus, Ohio, USA; 2Columbia University, New York, New York, USA
2066. Sex Difference and Age Dependence of the Human Brain Structure Delineated at the High Magnetic Field of 4.7T
Fumiyuki Mitsumori1, Nobuhiro Takaya1, Hidehiro Watanabe1 1Natl. Inst. Environ. Studies, Tsukuba, Ibaraki, Japan
Hall 14.1 Wednesday 13:30 - 15:30
2067. Morphological Differences in the Grey Matters of Mathematicians: A Voxel-Based Morphometry Study
Ozlem Ozmen Okur1, Ayaz Agayev2, Cengizhan Ozturk3, Kubilay Aydin2, Adem Ucar,2 Kader Karli Oguz4 1Bogazici University Biomedical Engineering, Istanbul, Turkey; 2Istanbul University, Istanbul Medical School, Istanbul, Turkey; 3Bogazici University Biomedical Engineering, Istanbul, Turkey, 4Hacettepe University, Medical School, Ankara, Turkey
2068. The Similarity of the Brain in Healthy Monozygotic Twins: A Voxel Based Analysis of Volume, T2 and DTI
Gaby S. Pell1, Regula S. Briellmann1, Kate Lawrence1, Debra Glencross1, Tony Waites1, Sam Berkovic1, Graeme D. Jackson1 1Brain Research Institute, W Heidelberg, VIC, Australia
2069. Haircut: A Method to Reduce the Dragging Effect Due to Smoothing in Voxel-Based Morphometry
Julio Acosta-Cabronero1, Joao Pereira1, Guy B. Williams1, Peter J. Nestor1 1University of Cambridge, Cambridge, UK
2070. Impact of Bias-Correction and Skull-Stripping Pipelines on Spatial Normalisation Using SPM5 in a Phantom Model
Julio Acosta-Cabronero1, Guy B. Williams1, Peter J. Nestor1 1University of Cambridge, Cambridge, UK
2071. Magnetic Resonance Image Classification Via Over-Complete Independent Component Analysis and Active Support Vector Machines
Clayton Chi-Chang Chen1, Jyh-Wen Chai2, Hsiang-Min Chen3, Tsung-Jung Li4, Yen-Chieh Ouyang3, Ching-Wen Yang1, San-Kan Lee5, Chein-I Chang6 1Taichung Veterans General Hospital, Taichung, Taiwan, Taiwan; 2Taichung VeteransGeneral Hospital, Taichung, Taiwan, Taiwan; 3National Chung Hsing University, Taichung, Taiwan, Taiwan; 4Chung Shan Medical University, Taichung, Taiwan, Taiwan; 5Yuanshan Veterans General Hospital, Yilan, Taiwan, Taiwan; 6University of Maryland, Baltimore County, Baltimore, Maryland, USA
2072. Improving Quantitative Analysis of Gray and White Matters in Brain Magnetic Resonance Imaging Based on Coupling Independent Component Analysis with Support Vector Machines
Jyh-Wen Chai1, Clayton Chi-Chang Chen2, Hsiang-Min Chen3, Tsung-Jung Li4, Yen-Chieh Ouyang3, Ching-Wen Yang2, San-Kan Lee5, Chein-I Chang6 1Taichung VeteransGeneral Hospital, Taichung, Taiwan, Taiwan; 2Taichung Veterans General Hospital, Taichung, Taiwan, Taiwan; 3National Chung Hsing University, Taichung, Taiwan, Taiwan; 4Chung Shan Medical University, Taichung, Taiwan, Taiwan; 5Yuanshan Veterans General Hospital, Yilan, Taiwan, Taiwan; 6University of Maryland, Baltimore County, Baltimore, Maryland, USA
2073. Reproducibility of Segmented Brain Volumes Using SPM5: Effects of Changes in Signal-To-Noise Ratio and Scanner Software
Borys Shuter1, 2, Berne Yeh1, Steven Graham2, Christopher Au1, Shih-Chang Wang1, 2 1National University Hospital, Singapore, Singapore; 2National University of Singapore, Singapore, Singapore
MR Techniques for Neuro: Miscellaneous Hall 14.1 Wednesday 13:30 - 15:30
2074. Blood-Pressure Dependent T2*-Mapping
Claus Kiefer1, Gerhard Schroth1, Roland Wiest1, Christoph Ozdoba1, Johannes Slotboom1, Luca Remonda1, Marwan ElKoussy1 1University Hospital, Bern, Switzerland
2075. Paramagnetic and Diamagnetic Cerebral Lesions in Susceptibility Weighted Phase Imaging (SWI)
Andreas Deistung1, Alexander Rauscher1, Hans-Joachim Mentzel1, Stephan Witoszynskyj1, Werner A. Kaiser1, Jürgen R. Reichenbach1 1Friedrich Schiller-University, Jena, Germany
2076. Susceptibility Weighted Imaging at 1.5T, 3T and 7T
Andreas Deistung1, Jan Sedlacik1, Alexander Rauscher1, Jörg Stadler2, Claus Tempelmann3, Johannes Bernarding3, Werner A. Kaiser1, Paul Müller1, Enrico Dittrich1, Jürgen R. Reichenbach1 1Friedrich Schiller-University, Jena, Germany; 2Leibniz Institute for Neurobiology, Magdeburg, Germany; 3Otto von Guericke University, Magdeburg, Germany
2077. Monitoring the Role and Metabolism of 13C-Hyperpolarized Steroids and Nonsteroidal Anti-Inflammatory Drugs Via Parahydrogen-Enhanced MRI
Joachim Bargon1, Ute Bommerich2, Rahim Rizi3 1University of Bonn, Bonn, Germany; 2University of Magdeburg, Germany; 3University of Pennsylvania, Philadelphia, Pennsylvania, USA
2078. Hyperpolarizing and Exploring the Function of Drugs Used to Combat Epilepsy Via Parahydrogen-Enhanced MRI
Joachim Bargon1, Ute Bommerich2, Rahim Rizi3 1University of Bonn, Bonn, Germany; 2University of Magdeburg, Germany; 3University of Pennsylvania, Philadelphia, Pennsylvania, USA
2079. Hyperpolarizing Drugs to Determine Their Role in Suppressing Epileptic Seizures and Migraine Headaches Via MRI
Joachim Bargon1, Ute Bommerich2, Rahim Rizi3 1University of Bonn, Bonn, Germany; 2University of Magdeburg, Germany; 3University of Pennsylvania, Philadelphia, Pennsylvania, USA
2080. Verification of Susceptibility Difference and Volume Fraction for the Calculation of Oxygenation Extraction Fraction Using Measurements of a Single Capillary and Network Phantom
Jan Sedlacik1, Alexander Rauscher1, Stephan Witoszynskyj1, Paul Müller2, Enrico Dittrich3, Werner A. Kaiser1, Jürgen R. Reichenbach1 1Friedrich Schiller Universität, Jena, Germany; 2Technische Univeristät Ilmenau, Ilmenau, Germany; 3Fachhochschule Jena, Jena, Germany
2081. Oxygen Effects in Tissue Preparation Neuronal Current MRI
Qingfei Luo1, Ho-Ling Liu2, Brent Parris1, Huo Lu3, David M. Senseman3, Jia-Hong Gao1 1University of Chicago, Chicago, Illinois, USA; 2Chang Gung University, Taiwan; 3University of Texas at San Antonio, San Antonio, Texas, USA
2082. Mapping BOLD Sensitivity to CO2 in the Human Brainstem
Kyle T S Pattinson1, Georgios D. Mitsis1, Ann K. Harvey1, Sharon Dirckx1, Stephen D. Mayhew1, Helen Hoar1, Richard Rogers1, Irene Tracey1, Richard G. Wise2 1Oxford University, Oxford, UK; 2Cardiff University, Cardiff, UK
2083. Decreased Glutamate Levels with Acute Exposure to Anesthetic Agent Propofol: A Preliminary In Vivo 1H Spectroscopy Study
Jeffrey A. Stanley1, George M. Mckelvey1, Aliakei Pustavoitau2, Kerry Murphy1, Dalal Khatib1, Harold M. Marsh1, Matthew P. Galloway1 1Wayne State Univ Sch Med, Detroit, Michigan, USA; 2John Hopkins University, Baltimore, Maryland, USA
2084. Anesthetic Effects of Sevoflurane and Propofol on Regional CBF: A Comparative MRI Study on Normal Subjects and Implications
Maolin Qiu1, Ramachandran Ramani1, Shu-Ming Wang1, Nallakandi Rajeevan1, Fuyuze S. Tokoglu1, Todd R. Constable1 1Yale University School of Medicine, New Haven, Connecticut, USA
2085. Brain Morphometry with Multiecho MPRAGE
Andre JW van der Kouwe1, Thomas Benner1, David H. Salat1, Bruce Fischl1, 2 1Massachusetts General Hospital, Charlestown, Massachusetts, USA; 2Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
2086. Clinical Experience of the Use of Gadolinium Contrast Agents for T1-Weighted 3D High Resolution Neurological Imaging
Terri Louise Watson1, Ulrika Estenberg1, Maria Kristoffersen Wiberg2 1Karolinska University Hospital, Huddinge, Stockholm, Sweden; 2Karolinska Institutet, Stockholm, Sweden
2087. High Contrast Imaging at High Field Strengths with Low SAR
Neelavalli Jaladhar1, Ewart Mark Haacke2 1Wayne State University, Detroit, Michigan, USA; 2Wayne State University, Michigan, USA
2088. Contrast Between Grey and White Matter in 7 T Phase Images and Its Potential for Segmentation
Andreas Schäfer1, Penny A. Gowland1, Richard W. Bowtell1 1University of Nottingham, Nottingham, UK
2089. A Robust Spherical Inflation Technique Using the Method of Concentric Rings
Min Jeong Kwon1, Jooyoung Hahn1, HyunWook Park1 1Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea
2090. Automatic Segmentation of Human Brain, Grey and White Matter in MRI: A Robust and Accurate Algorithm Based on the Tissues' Features Analysis
Manfredo Atzori1, Gianluca Rambaldelli1, Cinzia Perlini1, Marcella Bellani1, Nicola Dusi1, Silvia Sponda1, Michele Tansella1, Paolo Brambilla2 1University of Verona, Verona, Italy; 2University of Udine, Udine, Italy
2091. Automatic Measurements of Brain Tissue Volumes and Volume Distributions
Erin Jane McCormack-Kelly1, Sachin Jambawalikar2, Michael R. Egnor3, Zengmin Yan3, Mark E. Wagshul3 1Stony Brook University, Coram, New York, USA; 2Stony Brook University, Stony Brook, New York; 3Stony Brook University, Stony Brook, New York, USA
2092. Quantitation of Brain Tissue Swelling Using MRI
Rebecca J. Theilmann1, Edward Dyer1, Susan R. Hopkins1, Richard B. Buxton1, David J. Dubowitz1 1University of California San Diego, La Jolla, California, USA
2093. T1 Mapping to Identify Changes in Cortical Structure
Nurunisa Neyzi1, Stuart Clare2, Sean Deoni2 1Weill Cornell Medical College, New York, New York, USA; 2Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, Oxford University, Oxford, UK
2094. Diagnostic Features of Acute DWI Abnormalities of Different Origin in the Hippocampus
Kristina Szabo1, Rolf Kern1, Martin Griebe1, Simone Bukow1, Alex Förster1, Michael G. Hennerici1, Achim Gass1 1Universitätsklinikum Mannheim; University of Heidelberg, Mannheim, Germany
2095. Structural Correlates of Implicit Memory Learning Deficits in Developmental Dyslexia
Deny Menghini1, 2, Gisela Hagberg2, Stefano Vicari1, 3, Laura Petrosini, 24, Emiliano Macaluso2, Carlo Caltagirone2, 5, Marco Bozzali2 1IRCCS, Children’s Hospital “Bambino Gesù”, Santa Marinella, Rome, Italy; 2Santa Lucia Foundation, Rome, Italy; 3University LUMSA, Rome, Italy; 4University “La Sapienza”, Rome, Italy; 5University Tor Vergata, Rome, Italy
2096. Chronic and Incremental Effect of Hypoxia Due to Extreme High-Altitude Exposure Relate with Atrophy in Motor-Function Related Brain Areas
Margherita Di Paola1, Marco Bozzali1, Lucia Fadda2, Massimo Musicco3, Umberto Sabatini1, Carlo Caltagirone2 1Neuroimaging Laboratory, IRCCS S. Lucia Foundation, Rome, Italy, Italy; 2Department of Neurological Sciences, University of Rome “Tor Vergata”, Rome, Italy; 3National Research Council. Institute of Biomedical Technologies. Milan Italy. Ev-K2-CNR, Milan, Italy
2097. Subcortical Physiological Abnormalities in Type 2 Diabetes Detected Using Magnetization Transfer
Anand Kumar1, R.K. Gupta2, Olusola Ajilore1, Ebrahim Haroon3, Genevieve Rodriguez1, Albert Thomas2 1UCLA Semel Institute, Los Angeles, California, USA; 2UCLA, Los Angeles, California, USA; 3Emory University, Atlanta, Georgia, USA
2098. Polymorphic Deletion in DCDC2 Affects Brain Morphology - A Voxel Based Morphometric Study
Shashwath A. Meda1, Jeffrey R. Gruen2, Vince D. Calhoun2, 3, Joel Gelernter2, Haiying Meng2, Godfrey D. Pearlson1, 2 1Hartford Hospital, Hartford, Connecticut, USA; 2Yale University, New Haven, Connecticut, USA; 3University of New Mexico, Albuquerque, New Mexico, USA
2099. Cross-Sectional and Longitudinal Brain Morphometry in HIV Associated Cognitive Impairment
Ying Wu1, Pippa Storey2, Bruce Cohen, Leon Epstein, Robert Edelman2, Ann Ragin 1Evanston Northwestern Healthcare; Feinberg School of Medicine, Northwestern University., Evanston, Illinois, USA; 2Evanston Northwestern Healthcare; Feinberg School of Medicine, Northwestern University., Illinois, USA
2100. Brain Tissue Water Content Measured by MRI: Pre- Vs. Post-Shunt Chronic Hydrocephalus
XIAODONG GUO1, JIA-HONG GAO2, Richard D. Penn1 1University of Chicago, Chicago, Illinois, USA; 2University of Chicago, Chicago, Illinoise, USA
2101. Structural Brain Deficits in Smokers Measured by MR Volumetry at 3 T
Florian Schubert1, Frank Seifert1, Mario Staedtgen2, Jürgen Gallinat2 1Physikalisch-Technische Bundesanstalt, Berlin, Germany, Germany; 2Charite Universitätsmedizin, Berlin, Germany, Germany
2102. Brain MRI of Moving Subjects: Snapshot Images with Volume Reconstruction (SVR) Extended to Multi-Shot Sequences and Applied to Neonates and Adults
Shuzhou Jiang1, Hui Xue1, Mary A. Rutherford1, Adam Waldman1, Kate McLeish2, Derek Hill2, Daniel Rueckert, Joseph V. Hajnal1 1Hammersmith Hospital, Imperial College London, London, UK; 2University College London, London, UK
2103. T2 Relaxation Illustrates Correlation Between Myelin Development and Verbal IQ Scores in Young Males
Kirstie Whitaker1, Campbell M. Clarke1, Alex L. MacKay1 1University of British Columbia, Vancouver, BC, Canada
2104. Null Point Imaging
John James Totman1, Penny A. Gowland1, Alain Pitiot1 1University of Nottingham, Nottingham, UK
2105. The ADNI Phantom and Analysis Algorithm: A New and Accurate Tool to Measure Scanner Performance
Jeffrey L. Gunter1, Paula J. Britson1, Joel P. Felmlee1, Chadwick P. Ward1, Norbert Schuff2, Michael Weiner2, Josh Levy3, Clifford R. Jack,Jr. 1 1Mayo Clinic and Foundation, Rochester, Minnesota, USA; 2UC SanFrancisco, SanFrancisco, California, USA; 3The Phantom Laboratory, Salem, New York, USA
2106. Estimation of Fractional Contributions of White and Gray Matter by Cross-Regularized Inverse Laplace Transform
Christian Labadie1, Silvia Jarchow2, Harald E. Möller3 1905 chemin des Genêts, Saint-Dié, France; 2Riensbergerstr. 82, Bremen, Germany; 3Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany
2107. Morphometry of the Retrobulbar Human Optic Nerve: Comparison of 3T MRI with Conventional Sonography
Thorsten Alexander Bley1, Mathias Weigel1, Wolf Lagreze1, Alexander Lazzarro1, Alex Frydrychowicz1, Mathias Langer1, Juergen Hennig1 1University of Freiburg, Freiburg, Baden-Wuerttemberg, Germany
2108. Towards Quantitative Magnetic Resonance "Angstromscopy"
Sean CL Deoni1, 2, Catherine Traynor2 1Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, Oxford, England, UK; 2Institute of Psychiatry, London, England, UK
2109. A Comparison of T2- And T2*-Weighted Imaging at 7T
Christopher John Wiggins1, Graham Charles Wiggins1, Christina Triantafyllou1, Lawrence Wald1, Alma Gregory Sorensen1 1Massachusetts General Hospital, Charlestown, Massachusetts, USA
2110. Contrast Enhanced MR Imaging of the Brain Using T1-FLAIR with BLADE Compared with Conventional Spin Echo Sequence
Shinji Naganawa1, Hisashi Kawai1, Hiroshi Fukatsu1 1Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
2111. Geometric Reconstruction of Brain Vasculature from Small Rodents; a Comparison of Different Imaging Methods
Manuel Gaudnek1, Michael Siblia1, 2, Klaus Obermayer1, 3, Brune Kay4, Andreas Hess4 1Berlin University of Technology, Berlin, Germany; 2Bernstein Centre for Computational Neuroscience, Berlin, NA, Germany; 3Bernstein Centre for Computational Neuroscienc, Berlin, NA, Germany; 4I. f. Experimental Pharmacology, Erlangen, NA, Germany
2112. Evaluation of Anterior Choroidal Artery on 3T 3D TOF MRA
Yoshiyasu Hiratsuka1, Hitoshi Miki1, Keiichi Kikuchi1, Ikuko Kiriyama1, Teruhito Mochizuki1, Shizue Takahashi2, Ichiro Matsubara2, Kazuhiko Sadamoto2 1Ehime University School of Medicine, Toon, Ehime, Japan; 2Washo-kai Sadamoto Hospital, Matsuyama, Ehime, Japan
Motion Artifact Suppression - Brain Hall 14.1 Wednesday 13:30 - 15:30
2113. Detection and Measurement of Data Loss Due to MRI Interleave Positioning Errors
Roger Tam1, Andrew Riddehough1, Guojun Zhao1, Anthony Traboulsee1, David Li1 1University of British Columbia, Vancouver, British Columbia, Canada
2114. Motion Artifacts for Diffusion Spectrum Imaging
Wen-Yang Chiang1, Van J. Wedeen2, Timothy G. Reese3, Wen-Yih Isaac Tseng1 1National Taiwan University College of Medicine, Taipei, Taiwan; 2Harvard Medical School, Charlestown, Massachusetts, USA; 3Massachusetts General Hospital, Boston, Massachusetts, USA
2115. Improvement of DTI Measurement Accuracy Using Real-Time Navigated Data Acquisition
XIANFENG SHI1, Eugene Kholmovski2, Seong-Eun Kim2, Dennis L. Parker2, Eun-Kee Jeong2 1University of Utah, salt lake city, Utah, USA; 2University of Utah, Salt Lake City, Utah, USA
2116. High-Quality Non-Water Suppressed MR Spectra with Correction for Motion Induced Signal Reduction
Jyh-Miin Lin1, Shang-Yueh Tsai1, Chou-Ming Cheng2, Tzu-Chen Yeh2, Hua-Shan Liu1, 3, Robert V. Mulkern4, Hsiao-Wen Chung1, Nan-Kuei Chen5 1National Taiwan University, Taipei, Taiwan; 2Taipei Veterans General Hospital, Taipei, Taiwan; 3Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan; 4Children's Hospital and Harvard Medical School, Boston, Massachusetts, USA; 5Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
2117. Motion Insensitive 3D Imaging Using a Novel Real-Time Image-Based 3D PROspective MOtion Correction Method (3D PROMO)
Ajit Shankaranarayanan1, Cooper Roddey2, Nathan White2, Eric T. Han3, Daniel Rettmann4, Juan Santos5, Ehud Schmidt6, Anders Dale2 1GE Healthcare, Bethesda, Maryland, USA; 2University of California San Diego, San Diego, California, USA; 3GE Healthcare, Menlo Park, California, USA; 4GE Healthcare, Rochester, Minn, USA; 5Stanford University, Palo Alto, California, USA; 6GE Healthcare, Boston, Massachusetts, USA
2118. Optimization of Hybrid 2-Dimensional Navigator Correction to Suppress Respiratory-Induced Physiological Noise
Robert L. Barry1, 2, L. M. Klassen1, Ravi S. Menon1, 2 1Robarts Research Institute, London, Ontario, Canada; 2University of Western Ontario, London, Ontario, Canada
2119. Prospective Correction of Large Simple Through-Plane Motion
Sara Elizabeth Yancey1, Fred Tam2, Kevan James Thompson Anderson1, Labonny Biswas3, Graham A. Wright1, Simon J. Graham1, 4 1University of Toronto, Toronto, Ontario, Canada; 2Sunnybrook Hospital, Toronto, Ontario, Canada; 3The Hospital for Sick Children, Toronto, Ontario, Canada; 4Baycrest Hospital, Toronto, Ontario, Canada
2120. Ballistocardiogram Artifact Removal from EEG Signals Using the Real-Time Kalman Filter
Myung Ho In1, Hyun Chung Kim1, Tae Seok Park1, Tae-Seong Kim1, Min Hyoung Cho1, Soo Yeol Lee1 1Kyung Hee University, Yongin, Kyungki, Republic of Korea
2121. A Multi-Echo Approach to Removing Task-Correlated Motion Artefacts in fMRI
Pieter François Buur1, David Gordon Norris1 1F.C. Donders Centre for Cognitive Neuroimaging, Nijmegen, Netherlands
2122. The Effects of Slice-Timing and the Use of Registration Parameters as Covariates in the Analysis of fMRI Experiments Exhibiting Either Task-Correlated Motion or Residual Motion from Image-Based Motion Tracking.
Sebastiaan Gobets1, Jan-Henry Seppenwoolde1, Suzanne Koudijs1, Josien Pluim1, Matthias J.P. van Osch2 1University Medical Center Utrecht, Utrecht, Netherlands; 2Leiden University Medical Center, Leiden, Netherlands
Diffusion Imaging of Neurodegenerative Diseases Hall 14.1 Wednesday 13:30 - 15:30
2123. Progressive White Matter Microstructural Changes Following Mild Traumatic Brain Injury Revealed by Bootstrap Analysis of Serial 3T Diffusion Tensor MRI
SungWon Chung1, 2, Hana Lee2, Srivathsa Veeraraghavan2, Duan Xu2, Michele Meeker2, Jamshid Ghajar3, Geoffrey T. Manley2, Roland G. Henry1, 2, Pratik Mukherjee1, 2 1University of California San Francisco & Berkeley, San Francisco, California, USA; 2University of California San Francisco, San Francisco, California, USA; 3Brain Trauma Foundation, New York, New York, USA
2124. Improved Distortion Correction in Cerebral and Spinal DTI Using Interleaved Reversed Gradients
Man Cheuk Ng1, Seth A. Smith2, 3, Joseph S. Gillen2, 3, Bennett A. Landman2, D K. Luk4, y Hu4, Peter C.M. van Zijl2, 3, E S. Yang4 1The University of Hong Kong, Pokfulam, Hong Kong; 2Johns Hopkins University, Baltimore, Maryland, USA; 3Kennedy Krieger Institute, Baltimore, Maryland, USA; 4The University of Hong Kong, Pokfulam, Hong Kong
2125. Brain Diffusion Weighted Imaging Study of Friedreich Ataxia Patients
Raffaele Lodi1, Giovanni Rizzo1, Caterina Tonon1, David Manners1, Emil Malucelli1, Filippo Fortuna1, Claudia Testa1, Barbara Mostacci1, Antonella Pini2, Valerio Carelli1, Bruno Barbiroli1 1Università di Bologna, Bologna, Italy; 2U.O. Neuropediatria, Ospedale Maggiore, Bologna, Italy
2126. Diffusion Tensor Imaging in Parkinsonism – Analysis of Corticospinal Tracts and Association Bundles in Patients with Essential Tremor Vs Parkinson´s Disease by Quantitative Spatially Normalized DTI at 3.0T
Heiner Matthias Stiepani1, Alexander Hopt2, Michail Plotkin, Harald Bruhn1, Zhun Kyung-Hee1, Andreas Kupsch2, Soren Gartenschlager1, Florian Streitparth1, Karl Titus Hoffmann1 1Charite Virchow, Berlin, Germany; 2Charite,
2127. Increased Brain Diffusion in the Genu of HIV Patients at One-Year Follow-Up
Victoria Wong1, Linda Chang1, Helenna Nakama1, Michael Watters1, Christine Cloak1, Darlene Ramones1, Thomas Ernst1 1University of Hawaii, John A. Burns School of Medicine, Honolulu, Hawaii, USA
2128. DTI VBM Analysis of Pathological Progression in HIV Patients Underwent Associated Dementia
Tong Zhu1, Michelle Gaugh1, Kim Cruttenden1, David Gill1, Kevin Biglan1, Jianhui Zhong, 12, Giovanni Schifitto1 1University of Rochester, Rochester, New York, USA; 2University of Rochesterr, Rochester, New York, USA
2129. White Matter Changes in Chronic Cocaine Users Revealed by Voxelwise Group Analysis of Diffusion Tensor Imaging
Wang Zhan1, Hong Gu1, Thomas J. Ross1, Betty Jo Salmeron1, Elliot A. Stein1, Yihong Yang1 1National Institute on Drug Abuse, Baltimore, Maryland, USA
2130. DTI-Based Analysis Facilitates the Understanding of a Peculiar Neuropsychological Dissociation in a Patient with Bilateral Thalamic Damage
Andrea Cherubini1, Giovanni Augusto Carlesimo, 12, Laura Serra1, Lucia Fadda, 12, Marco Bozzali1 1Santa Lucia Foundation, Rome, Italy; 2Tor Vergata University, Rome, Italy
2131. Selective Damage of the Visual Pathways in Patients with Migraine: A MR Tractography Study at 3 T
Maria Assunta Rocca1, Elisabetta Pagani1, Paola Tortorella1, Bruno Colombo1, Andrea Falini1, Giuseppe Scotti1, Giancarlo Comi1, Massimo Filippi, 12 1Scientific Institute and University Ospedale San Raffaele, Milan, Italy; 2Scientific Institute and University, Hospital San Raffaele, Milan, Italy, Italy
Brain Degeneration: Ataxias & Dementias Hall 14.1 Wednesday 13:30 - 15:30
2132. Assessment of Oxidative Stress and Neuronal Viability in Friedreich’s Ataxia by 1H MRS at 4 Tesla
Gulin Oz1, Isabelle Iltis1, Diane Hutter1, Christopher M. Gomez2 1University of Minnesota, Minneapolis, Minnesota, USA; 2University of Chicago, Chicago, Illinois, USA
2133. Diffusivity and Diffusion Anisotropy of Cerebellar Peduncles in the Cases of Spinocerebellar Ataxia. - Short-Range Tractography Based Analysis in Order to Avoid Crossing Fiber Problem-
Toshiaki Taoka1, Tesseki Kin1, Hiroyuki Nakagawa1, Masahiko Sakamoto1, Satoru Iwasaki2, Makito Hirano1, Satoshi Ueno1, Kimihiko Kichikawa1 1Nara Medical University, Kashihara, Nara, Japan; 2Higashiosaka City General Hospital, Higashiosaka, Osaka, Japan
2134. Decreased Anisotropy in the Corpus Callosum of Patients Suffering from Limb Kinetic Apraxia
Jan-Hendrik Buhk1, Matthias Küntzel2, Kai Kallenberg1, Jens Frahm2, Walter Paulus1, Peter Dechent1 1University of Göttingen, Göttingen, Germany; 2Max-Planck-Institut für biophysikalische Chemie, Göttingen, Germany
2135. Characterization of Cerebellar Metabolic Alterations in Ataxia with Oculomotor Apraxia (AOA2)
Isabelle Iltis1, Diane Hutter1, Christopher M. Gomez2, Gulin Oz1 1University of Minnesota, Minneapolis, Minnesota, USA; 2University of Chicago, Chicago, Illinois, USA
2136. Quantitative SWI in Differentiation of MSA and Parkinson's Disease
Feng Feng1, Hui You1, Han Wang1, Hao Shen2, Fuling Zheng1, Hongyi Sun1, Zhengyu Jin1 1Peking Union Medical College Hospital, Beijing, People’s Republic of China; 2GE Healthcare China, Beijing, People’s Republic of China
2137. Diffusion Weighted Imaging Differentiates Corticobasal Degeneration from Progressive Supranuclear Palsy and Parkinson’s Disease
Giovanni Rizzo1, 2, David Neil Manners1, Caterina Tonon1, Cesa Scaglione2, Barbara Mostacci1, Emil Malucelli1, Valerio Maruotti2, Paolo Martinelli2, Raffaele Lodi1, Bruno Barbiroli1 1Bologna University, Bologna, Italy; 2University of Bologna, Bologna, Italy
2138. 31P MRS of the Brain Supports the Mitochondrial Hypothesis for Huntington Disease, Revealing Altered ATP Synthesis, pH Increase and Stable ATP Level
Myriam Chaumeil1, Hélène Bataille1, Julien Valette1, Emmanuel Brouillet1, Véronique Gaura1, Anne Catherine Bachoud-Levi2, Pierre Krystkowiak3, Christophe Verny4, Philippe Damier5, Amandine Rialland2, Gilles Bloch1, Philippe Hantraye1, Philippe Remy1, 2, Vincent Lebon1, 6 1CEA-CNRS, Orsay, France; 2CHU Henri Mondor, Créteil, France; 3CHRU Roger Salengro, Lille, France; 4CHRU Larrey, Angers, France; 5CHRU Guillaume et Rene Laënnec, Nantes, France; 6CEA-NeuroSpin, Gif-sur-Yvette, France
2139. First Study of Therapy Follow-Up of Creutzfeldt-Jakob Disease by Magnetic Resonance Diffusion and Spectroscopy
Danielle Ibarrola1, Alain Vighetto2, Pierre Krolak-Salmon2, Marc Hermier3, Jean-Claude Froment3, Dominique Sappey-Marinier1, 4 1IFR19, CERMEP - Imagerie du vivant, Bron, France; 2Neurologie, Hôpital Neurologique, Bron, France; 3Neuroradiologie, Hôpital Neurologique, Bron, France; 4CREATIS CNRS UMR5515 & INSERM U630 - Université Claude Bernard, Lyon, France
2140. 3 Tesla MR Spectroscopy Reveals Decreased Glutamate and Glutamine Levels in Frontal White Matter in HIV-Associated Dementia
Mona A. Mohamed1, Ned C. Sacktor1, Richard L. Skolasky1, Richard T. Moxley1, Martin G. Pomper1, Peter B. Barker1 1Johns Hopkins University Sch of Med, Baltimore, Maryland, USA
Hall 14.1 Wednesday 13:30 - 15:30
2141. Towards a 10 Minute Clinical Alzheimer MR Imaging Protocol
Gunnar Krueger1, Hubertus Fischer2, Karsten Jahns2, Daniel Driemel2, Arne Littmann2, Stephan Kannengiesser2, Alma Greg Sorensen3, Matt A. Bernstein4, Paula J. Britson4, Chadwick P. Ward4, Jeffrey L. Gunter4, Denise A. Reyes4, Clifford R. Jack Jr. 4 1Siemens Medical Solutions, Lausanne, Switzerland; 2Siemens Medical Solutions, Erlangen, Germany; 3Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA; 4Mayo Clinic and Foundation, Rochester, Minnesota, USA
2142. Whole Brain Atrophy Rate in Relation to Cognitive Decline in Alzheimer’s Disease and Mild Cognitive Impairment
Jasper D. Sluimer1, Wiesje M. van der Flier1, Nick C. Fox2, Philip Scheltens1, Frederik Barkhof1, Hugo Vrenken1 1VU Medical center, Amsterdam, Netherlands; 2University College London, UK
2143. Degeneration of Subcortical White Matter in Alzheimer's Disease: Topographical Analysis
Takashi Yoshiura1, Tomoyuki Noguchi1, Akio Hiwatashi1, Osamu Togao1, Koji Yamashita1, Seiji Kumazawa1, Futoshi Mihara1, Hiroshi Honda1 1Kyushu University, Fukuoka, Japan
2144. Local Volumetric Analysis of the Brain Ventricles in Alzheimer's Disease Using MRI
Hans Olofsen1, Luca Ferrarini1, Walter Miguel Palm, Mark A. van Buchem, Johan H.C. Reiber1, Faiza Admiraal-Behloul1 1LKEB - Leiden University Medical Center, Leiden, Netherlands
2145. Automated Hippocampal Volumetry in Alzheimer’s Disease, Mild Cognitive Impairment and Normal Aging
Olivier Colliot1, Gaël Chételat2, Marie Chupin1, 3, Béatrice Desgranges2, Dominique Hasboun1, Bruno Dubois4, Stéphane Lehéricy4, 5, Francis Eustache2, 6, Line Garnero1, 7 1CNRS - Université Pierre et Marie Curie Paris 6 - Hôpital de la Pitié-Salpêtrière, Paris, France; 2Inserm-EPHE-Université de Caen Basse-Normandie, Unité E 0218, GIP Cyceron, CHU de Caen, Caen, France; 3Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, UK; 4INSERM U610, Université Pierre et Marie Curie - Paris 6, Hôpital de la Pitié-Salpêtrière, Paris, France; 5IFR 49; 6EPHE, CNRS UMR 8581, Université René Descartes, Paris, France; 7IFR 70,
2146. Quantitative T2 Relaxation of White Matter Hyperintensities in Probable Alzheimer Patients
Wendy Oakden1, Nancy Lobaugh1, Sandra Black1, Greg Jan Stanisz1 1Sunnybrook HSC, Toronto, Ontario, Canada
2147. Association of Regional Atrophy, MRI-Guided SPECT Perfusion, and Memory Performance in Patients with Mild Cognitive Impairment Compared to Healthy Elderly Controls
Min-Ying Su1, Huali Wang2, Rahyeong Juh1, Ke Nie1, Yong Chu1, Alberto Bert1, Mark Mandelkern3, Orhan Nalcioglu1 1University of California, Irvine, California, USA; 2Peking University Institute of Mental Health, Beijing, People’s Republic of China; 3University of California, Irvine, California, USA
2148. Preliminary Cross-Sectional MRI-Derived ROI-Based Analysis of PET Data from the Alzheimer’s Disease Neuroimaging Initiative
David S. Karow1, Christine Fennema-Notestine2, Donald J. Hagler Jr. 2, Elaine Wu2, James B. Brewer2, Adam S. Fleisher2, Eric T. Han3, Carl K. Hoh2, Anders M. Dale2 1University of California, San Diego, La Jolla, California, USA; 2University of California, San Diego, California, USA; 3GE Healthcare, Menlo Park, California, USA
2149. Conserved Patterns of White Matter Hyperintensity Distribution in Alzheimer's, Cerebral Amyloid Angiopathy, and Healthy Aging
Christopher Michael Holland1, 2, Eric E. Smith3, Istvan Csapo1, M. Edip Gurol3, Douglas A. Brylka1, Charles R. G. Guttmann1, Steven Mark Greenberg3 1Brigham and Women's Hospital, Boston, Massachusetts, USA; 2Boston University School of Medicine, Boston, Massachusetts, USA; 3Massachusetts General Hospital, Boston, Massachusetts, USA
2150.
Is a Progressive Increase in the Number of Microhemorrhages
in the Aged an Earlier
E. Mark Haacke1, 2, Muhammad Ayaz1, Alexander S. Boikov2, Bharani Krishnamurthy1, Elena S. Manova1, April Dickson3, Cindy Dickson3, Wahed Baqai3, William Britt3, Wolff Kirsch3, Daniel Kido3, Floyd Petersen3 1Wayne State University, Detroit, Michigan, USA; 2MRI institute for biomedical researchers, Detroit, Michigan, USA; 3Loma Linda University, Loma Linda, California, USA
2151. Effects of Cardiovascular Disease Risk Factors on Regional Cerebral Blood Flow in Dementia
Weiying Dai1, Oscar L. Lopez1, Owen T. Carmichael2, James T. Becker1, Lewis H. Kuller1, H Michael Gach, 13 1University of Pittsburgh, Pittsburgh, Pennsylvania, USA; 2University of California, Davis, California, USA; 3Nevada Cancer Institute, Las Vegas, Nevada, USA
Imaging of Aging: Adolescents to Elders Hall 14.1 Wednesday 13:30 - 15:30
2152.
Evaluating Structural Brain Changes in Adolescence with
Magnetic Resonance
William R. Riddle1, Susan C. DonLevy1, Curtis A. Wushensky1, Benoit M. Dawant1, J Michael Fitzpatrick1, Ronald R. Price1 1Vanderbilt University, Nashville, Tennessee, USA
2153. In Vivo Imaging of Myelin Development in Young Males Using T2 Relaxation
Kirstie Whitaker1, Campbell M. Clarke1, Alex L. MacKay1 1University of British Columbia, Vancouver, BC, Canada
2154.
Microstructure in Subcortical White Matter in Individual
Cortical Regions: Age-Related Changes
Takashi Yoshiura1, Tomoyuki Noguchi1, Akio Hiwatashi1, Osamu Togao1, Koji Yamashita1, Seiji Kumazawa1, Futoshi Mihara1, Hiroshi Honda1 1Kyushu University, Fukuoka, Japan
2155.
Relationship Between Body Fat Composition and Concentrations
of Brain N-Acetyl-Aspartate
Stefan Gazdzinski1, John Kornak2, Michael W. Weiner2, 3, Dieter Johannes Meyerhoff2 1Northern California Institute for Research and Education, San Francisco, California, USA; 2University of California, San Francisco, California, USA; 3CIND, San Francisco, California, USA
2156. The Age and Gender Dependence of Total Transverse Relaxation Rate in Normal Human Brain at 3 T
Jianli Wang1, Xiaoyu Sun1, Erin Zimmerman1, Michael B. Smith1, Jianzhong Yin2, Ji Qi2, Qing X. Yang1 1Penn State College of Medicine, Hershey, Pennsylvania, USA; 2Tianjin First Central Hospital, Tinjin, People’s Republic of China
2157. Multivariate-Defined Spatial Networks of Age-Associated Atrophy
Adam M. Brickman1, Christian Habeck1, Marco A. Ramos1, Joseph Flynn1, Yaakov Stern1 1Columbia University, New York, New York, USA
2158.
Age Dependence in Phase Images of Human Brain at 3T and 7T:
Implications for
Georgeta Mihai1, Amir M. Abduljalil1, Peter A. Wassenaar1, Donald W. Chakeres1, Michael V. Knopp1, Petra Schmalbrock1 1The Ohio State University, Columbus, Ohio, USA
2159.
Decline in Extent Macroscopic Cerebral Vasculature with Age
Quantified Using
James Myers1, Hui Xue1, Adam Waldman2, Daniel Rueckert, Jo Hajnal1 1Hammersmith Hospital, Imperial College London, London, UK; 2Charing Cross Hospital, London, UK
2160. DTI and MTI Parameters Correlate in Periventricular White Matter Hyperintensities in Old Age
Mark E. Bastin1, Jonathan D. Clayden1, Alison Pattie1, Iona F. Gerrish1, Joanna M. Wardlaw1, Ian J. Deary1 1University of Edinburgh, Edinburgh, Mid Lothian, UK
2161.
Tensor-Based Morphometry and Classifier Algorithms for the
Identification of Structural
Promiti Dutta1, Robert Tamburo1, Minjie Wu1, Meryl Butters1, Charles Reynolds1, Howard Aizenstein1 1University of Pittsburgh, Pittsburgh, Pennsylvania, USA
2162. Working Memory as a Function of Cognitive Decline in Old Age: An fMRI Study
Gordon D. Waiter1, Helen C. Fox1, Alison D. Murray1, John M. Starr2, Ian J. Deary2, Lawrence J. Whalley1 1University of Aberdeen, Aberdeen, UK; 2University of Edinburgh, Edinburgh, UK
2163. Attention Inhibitory Process Decline During Life Span: A Functional MRI Study
Alexandre MATHIS1 1FORENAP, ROUFFACH, France
Hall 14.1 Wednesday 13:30 - 15:30
2164. Evaluation of Brain Iron In Vivo with Susceptibility Weighted Imaging
Xiaojun Xu1, Qidong Wang1, Minming Zhang1, Guang Cao2 1First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China; 2GE Healthcare China,
2165. Brain Iron in MR Imaging: R2* and Phase Shift at Different Field Strengths
Bing Yao1, Peter van Gelderen1, Jacco A. de Zwart1, Jeff H. Duyn1 1National Institutes of Health, Bethesda, Maryland, USA
2166. Association of Neurodegenerative Markers with T2 Hypointensities in the Basal Ganglia
Jeroen van der Grond1, Ahmet Ekin2, Adriaan van Es, Mark van Buchem, Rene Engbers2, Arianne van Muiswinkel3, Radu Jasinschi2 1LUMC, Leiden, Netherlands; 2Philips Research; 3Philips Medical Systems,
2167. Toward Clinically Practical T2-Mapping for Neurodegenerative Diseases
David Henderson1, John Schenck1, 2, Natalie Staples1, Earl Zimmerman2 1GE Global Research, Schenectady, New York, USA; 2Albany Medical College, Albany, New York, USA
2168. Using Direct Water Saturation for Sensitive Detection of Iron in the Human Brain
Seth Aaron Smith1, 2, Jeff W.M. Bulte2, Peter C.M. van Zijl1, 2 1Kennedy Krieger Institute, Baltimore, Maryland, USA; 2Johns Hopkins University, Baltimore, Maryland, USA
2169. Characterization of the Substantia Nigra in Elderly Subjects by Multi-Modality MRI
Yossi Yovel1, Efrat Sasson1, Yaniv Assaf1 1Tel Aviv University, Tel Aviv, Israel
2170.
In Vivo Measurement of Iron Deficiency in Restless Legs
Syndrome (RLS) with
Byeong-Yeul Lee1, Elana Farace2, Jeffrey Vesek1, Jianli Wang1, James R. Connor1, Qing Yang1 1Penn State Hershey Medical Center, Hershey, Pennsylvania, USA; 2Penn state Hershey Medical Center, Hershey, Pennsylvania, USA
2171. The Pattern of Brain Iron Accumulation During Normal Aging
Xiaojun Xu1, Minming Zhang1, Qidong Wang1, Fei Sun2 1First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China; 2GE Healthcare China,
2172. Gender Differences in Brain Iron Level
Xiaojun Xu1, Minming Zhang1, Qidong Wang1, Fei Sun2 1First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China; 2GE Healthcare China,
2173. Estimation of Tissue Iron Contribution to 1H2O R1 Values in Human Brain
William D. Rooney1, 2, Glyn Johnson3, Xin Li1, Jeffrey M. Njus1, Thomas M. Barbara1, Kamil Ugurbil4, 5, Charles S. Springer1 1Oregon Health and Science University, Portland, Oregon, USA; 2Brookhaven National Laboratory, Upton, New York, USA; 3New York University, New York, New York; 4University of Minnesota, Minneapolis, Minnesota, USA; 5Max Planck Institute, Tubingen, Germany
2174. Iron in Basal Ganglia Causes Weak Reproducibility of T2-Weighted Images at 3.0 Tesla
Jacobus FA Jansen1, M Eline Kooi1, Alfons G. Kessels1, Klaas Nicolay2, Walter H. Backes1 1Maastricht University Hospital, Maastricht, Netherlands; 2Eindhoven University of Technology, Eindhoven, Netherlands
2175.
Signal and Shape of Subthalamic Nucleus on
Susceptibility-Weighted Image (SWI).
Toshiaki Taoka1, Yasushi Kubota2, Hidehiro Hirabayashi1, Hiroyuki Nakagawa1, Masahiko Sakamoto1, Satoru Iwasaki3, Shinji Hirohashi4, Shiro Nakanishi2, Kimihiko Kichikawa1 1Nara Medical University, Kashihara, Nara, Japan; 2Hirai Hospital, Kashihara, Nara, Japan; 3Higashiosaka City General Hospital, Higashiosaka, Osaka, Japan; 4Osaka Gyoumeikan Hospital, Osaka, Japan
Hall 14.1 Wednesday 13:30 - 15:30
2176.
Persistent Distal White Matter Microstructural Changes Caused
by New Lesions at the Earliest
SungWon Chung1, 2, Daniel Pelletier2, Darin T. Okuda2, Roland G. Henry1, 2 1University of California San Francisco & Berkeley, San Francisco, California, USA; 2University of California San Francisco, San Francisco, California, USA
2177. Tract-Based Spatial Statistics: Application to the Study of Multiple Sclerosis
Caterina Mainero1, David H. Salat1, Francesca Caramia2, Luca Prosperini2, Carlo Pozzilli2, Bruce R. Rosen1 1MGH, Charlestown, Massachusetts, USA; 2University of Rome "La Sapienza", Rome, Italy
2178. Increased Fractional Anisotropy in Cortical Lesions in Multiple Sclerosis
Aziz Hatim Poonawalla1, Rakesh K. Gupta2, Khader M. Hasan1, Chul W. Ahn1, Flavia Nelson1, Jerry Wolinsky1, Ponnada A. Narayana1 1The University of Texas Medical School at Houston, Houston, Texas, USA; 2King George’s Medical University, Lucknow, India
2179.
A Spatial Normalized Study of Diffusion Tensor Imaging in
Clinically Isolated Syndrome
Yasheng Chen1, Valerie Jewells1, Christopher Sayed1, Silva Markovic-Plese1, Hongyu An1, Elizabeth Bullitt1, Weili Lin1 1The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
2180. Diffusion Tensor Imaging at 7 Tesla: Initial Application to Multiple Sclerosis
Meredith Metcalf1, Daniel Pelletier1, Duan Xu1, Darin T. Okuda1, Radhika Srinivasan1, Doug Kelley2, Sarah J. Nelson1, Daniel B. Vigneron1 1University of California, San Francisco, California, USA; 2GE Healthcare, San Francisco, California, USA
2181.
Relation Between Axonal Damage and Inflammation by 1H-MRSI
and T2-Weighted Lesion
M.Carmen Carmen Martinez-Bisbal1, 2, Ana Maria Pascual3, Beatriz Martinez-Granados1, Caridad Valero3, Francisco Coret4, Isabel Bosca3, Luis Marti-Bonmati2, Bonaventura Casanova3, Bernardo Celda1 1Universitat de Valencia, Burjassot, Valencia, Spain; 2Clinica Quiron, Valencia, Spain; 3Hospital La Fe, Valencia, Spain; 4Hospital Clinico, Valencia, Spain
2182.
Discriminating Multiple-Sclerosis Patient Groups : A
Principal-Component Analysis of CSF
Norbert W. Lutz1, Angèle Viola1, Irina Malikova1, Sylviane Confort-Gouny1, Jean-Philippe Ranjeva1, Jean Pelletier1, Patrick J. Cozzone1 1Faculté de Médecine de Marseille, Université de la Méditerranée, Marseille, France
2183. Metabolic Abnormality in Early Multiple Sclerosis Observed by Proton MRS
Harald E. Möller1, Timm Wetzel1, Marc Tittgemeyer, 12, Stefanie Hoffmann1, Derek V. M. Ott1, Christoph Preul1, 3, D. Yves von Cramon1, 2 1Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; 2Max Planck Institute for Neurological Research, Cologne, Germany; 3University Hospital Jena, Jena, Germany
2184. A New Metabolite Characteristic of Inflammatory MS Plaques: The First MRS Assignment of β-Hydroxyisobutyrate in CSF
Norbert W. Lutz1, Angèle Viola1, Irina Malikova1, Sylviane Confort-Gouny1, Jean-Philippe Ranjeva1, Jean Pelletier1, Patrick J. Cozzone1 1Faculté de Médecine de Marseille, Université de la Méditerranée, Marseille, France
2185. WITHDRAWN 2186. Delayed Conscious Access Related to Associative White Matter Fiber Tracts Injury in Patients with Early Relapsing Remitting Multiple Sclerosis
Françoise Reuter1, Bertrand Audoin1, Antoine Delcul2, Sylviane Confort-Gouny1, Jean-Philippe Ranjeva1, Patrick J. Cozzone1, Stanislas Dehaene2, Jean Pelletier1 1Faculté de Médecine de Marseille, Université de la Méditerranée, Marseille, France; 2SHFJ, CEA, Orsay, France
2187. Reproducibility of Quantitative Magnetization Transfer Imaging Parameters
Ives R. Levesque1, Sridar Narayanan1, Luciana Torres Ribeiro1, John G. Sled2, Doug L. Arnold1, G. Bruce Pike1 1Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada; 2Hospital for Sick Children, Toronto, Ontario, Canada
2188. Inhomogeneous Magnetization Transfer Imaging of Myelin Concentration in Multiple Sclerosis
David C. Alsop1, 2, Ram Dandamudi, 23, Rohit Bakshi, 23 1Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA; 2Harvard Medical School, Boston, Massachusetts, USA; 3Brigham & Women's Hospital, Boston, Massachusetts, USA
2189. MTR Abnormalities in Relapse Onset MS Patients 20 Years After the Onset of Disease
Leonora K. Fisniku1, Peter A. Brex2, Daniel J. Tozer1, Mara Cercignani1, Daniel R. Altmann1, 3, Katherine Miszkiel4, Klaus Schmierer1, Alan J. Thompson1, David H. Miller1 1Institute of Neurology, London, UK; 2Kings College Hospital, London, UK; 3London School of Hygiene and Tropical Medicine; 4National Hospital for Neurology and Neurosurgey, London, UK
2190. In Vivo Application of Quantitative Mapping of Myelin Water Fraction Using T2* Decay
DOSIK HWANG1, Yiping P. Du1 1University of Colorado Heath Science Center, Denver, Colorado, USA
2191.
Optimization of Multi-Compartment Analysis of T2* Decay in
Myelin Water Fraction Mapping with
DOSIK HWANG1, Yiping P. Du1 1University of Colorado Heath Science Center, Denver, Colorado, USA
2192. Left-Right Differences in 1H2O T1 Values of Multiple Sclerosis Normal Appearing Brain Tissue
Jeffrey M. Njus1, Leif Vigeland1, Xin Li1, 2, Charles S. Springer1, 2, Maria Taylor3, Frank W. Telang2, Patricia K. Coyle3, William D. Rooney1, 2 1Oregon Health & Science University, Portland, Oregon, USA; 2Brookhaven National Laboratory, Upton, New York, USA; 3Stony Brook University, Stony Brook, New York, USA
2193.
Quantitative DCE 1H2O R1
Measurements Suggest Increased Fractional Blood Water in
Jeffrey M. Njus1, Leif Vigeland1, Xin Li1, Charles S. Springer1, Maria Taylor2, Frank W. Telang3, Patricia K. Coyle2, William D. Rooney1 1Oregon Health & Science University, Portland, Oregon, USA; 2Stony Brook University, Stony Brook, New York, USA; 3Brookhaven National Laboratory, Upton, New York, USA
2194. Determining the Age of Multiple Sclerosis Lesions Using Myelin Water Imaging
Irene Margaret Vavasour1, Cornelia Laule1, David KB Li1, Anthony L. Traboulsee1, Alex L. MacKay1 1University of British Columbia, Vancouver, BC, Canada
Hall 14.1 Wednesday 13:30 - 15:30
2195. Selective Involvement of the Amygdala in Systemic Lupus Erythematosus
Bart Emmer1, Jeroen van der Grond1, Gerda Steup1, Tom Huizinga1, Mark van Buchem1 1Leiden University Medical Centre, Leiden, Netherlands
2196. MS Repair Potential and Disease Progression from Short-Term T2 Change
Dominik S. Meier1, Howard L. Weiner1, Charles R.G. Guttmann1 1Brigham & Women's Hospital, Boston, Massachusetts, USA
2197. Deep Gray Matter ‘Black T2’ Correlates with Disability in the Minocycline Treated Multiple Sclerosis Patients
Yunyan Zhang1, Luanne M. Metz1, V Wee Yong1, J Ross Mitchell1 1University of Calgary, Calgary, AB, Canada
2198. Development of Central Atrophy May Lead to Underestimation of Lesion Accrual in Patients with Multiple Sclerosis
Michael G. Dwyer1, Ondrej Dolezal2, Sara Hussein1, Dana Horakova2, Eva Havrdova2, Jennifer L. Cox1, Robert Zivadinov1 1Buffalo Neuroimaging Analysis Center, Buffalo, New York, USA; 2Charles University, Prague, Czech Republic
2199. Pathophysiologically Relevant Perivascular Processes in Multiple Sclerosis – Can We Detect Them In Vivo by MRI?
Jens Thomas Wuerfel1, Mareile Haertle1, Friedemann Paul1, Helmar Waiczies1, Frauke Zipp1 1Charite University Medicine Berlin, Berlin, Germany
2200. Detection of Hippocampal Lesions in Multiple Sclerosis with 3D-DIR
Stefan Dirk Roosendaal1, Bastiaan Moraal1, Hugo Vrenken1, Petra J.W. Pouwels1, Jonas A. Castelijns1, Frederik Barkhof1, Jeroen J. G. Geurts1 1VU University Medical center, Amsterdam, Netherlands
2201. Quantitative Analysis of MR-Defined White Matter Hyperintensities in Late-Life Depression.
KiSueng Choi1, Paul E. Holtzheimer III, Scott Peltier1, William McDonald, Helen S. Mayberg, Xiaoping Hu1 1Georgia Tech and Emory University, Atlanta, Georgia, USA
2202. Determinants of Disability in Multiple Sclerosis: A Cross-Sectional, Multiparametric, Quantitative Mr-Based Study of Disease Phenotypes
Annalisa Pulizzi1, Marco Rovaris1, Elda Judica1, Maria Pia Sormani1, 2, Vittorio Martinelli1, Andrea Falini1, Giancarlo Comi1, Massimo Filippi1 1Scientific Institute and University Hospital San Raffaele, Milan, Italy; 2University of Genoa, Genoa, Italy
2203. Optimisation of 3D Inversion Recovery Fast Spin Echo for Lesion Detection in Multiple Sclerosis Brain
Klaus Schmierer1, Simon J. Meara2, David H. Miller1, Gareth J. Barker3, Mara Cercignani1 1Institute of Neurology, UCL, London, UK; 2University of Manchester, Manchester, UK; 3Institute of Psychiatry, KCL, London, UK
2204. Gradient Echo Plural Contrast Imaging for Evaluating Multiple Sclerosis
Adil Bashir1, Anne H. Cross1, Dmitriy A. Yablonskiy1 1Washington University in St. Louis, St. Louis, Missouri, USA
2205. USPIO-Enhanced Cellular Imaging in MS
Machteld M. Vellinga1, Jeroen J. Geurts1, Susanne M. van der Pol2, Christiane Pering3, Chris H. Polman1, Helga E. de Vries2, Frederik Barkhof1 1MS Center Amsterdam, VU University Medical Center, Amsterdam, Netherlands; 2MS Center Amsterdam, VU University Medical Center, Amsterdam, Netherlands; 3Schering AG, Berlin, Germany
Hall 14.1 Wednesday 13:30 - 15:30
2206. A Learning by Example Approach for MRI Analysis of Human Brain in the Context of Mental Health
Paolo Brambilla1, Loris Bazzani2, A Tosato2, Vittorio Murino2, Gianluca Rambaldelli2, Cinzia Perlini2, Manfredo Atzori2, Michele Tansella2, Umberto Castellani2 1University of Udine, Udine, Italy; 2University of Verona, Verona, Italy
2207. Investigating the Structural Integrity of Brain Tissue in Intermittent Explosive Disorder: A Turboprop-DTI and Voxel-Based Morphometry Study
Huiling Peng1, Konstantinos Arfanakis1, K Luan Phan2, Emil L. Coccaro2 1Illinois Institute of Technology, Chicago, Illinois, USA; 2University of Chicago, Chicago, Illinois, USA
2208. White Matter Impairments as an Endophenotype of Bipolar Disorder – A Diffusion Imaging Study of Patients with Bipolar 1 Disorder and Their Unaffected Relatives
Christopher Andrew Chaddock1, Nicolette Marshall1, Katja Schulze1, Xavier Chitnis1, Robin Murray1, Colm McDonald2, Gareth Barker1 1Institute of Psychiatry, London, UK; 2National University of Ireland, Galway, Ireland
2209. Cortical Expression of Cognitive Control in the Bipolar Disorder Revealed by fMRI
Wen-Jui Kuo1, Tzu-Chen Yeh2, Jen-Chuen Hsieh2, Tung-Ping Su2 1National Yang-Ming University, Taipei, Taiwan; 2Taipei Veterans General Hospital, Taipei, Taiwan
2210. Alterations of Phosmomono- and Phosphodiesters in the Brain of Patients with Major Depression Detected with 3D 31P RINEPT
Gabriele Ende1, Tim Wokrina1, Helga Welzel1, Sigi Walter1, Traute Demirakca1, Christine Kief1, Fritz A. Henn2, Alexander Sartorius1 1Central Institute of Mental Health, Mannheim, Germany; 2Brookhaven National Laboratory, Upton, New York, USA
2211. Event Related fMRI of Successfully Implicitly Encoded Negative and Neutral Words in Major Depressive Disorder. Preliminary Results from the NESDA Neuroimaging-Study
Marie-Jose van Tol1, Marscha Mansvelt1, N.J.A. van der Wee1, D.J. Veltman2, M.M.A. Nielen2, F.G. Zitman1, A. Aleman3, R. Demenescu3, R.J. Renken3, M.A. van Buchem4 1LUMC, Leiden, Netherlands; 2VUmc, Netherlands; 3UMCG, Netherlands; 4LUMC, Netherlands
2212. Working Memory in Major Depression – An fMRI-Study at 3 T
Harald Kugel1, Sonja Schöning1, Katarina Lipina1, Almut Engelien1, Andreas Behnken1, Sebastian Schäfer1, Hagen Schiffbauer1, Irina Brote1, Bernhard Baune1, Volker Arolt1, Walter Heindel1, Carsten Konrad1 1University of Muenster, Muenster, NRW, Germany
2213. MRI Study of Cerebral Asymmetry in Patients with First-Episode Treatment Naive Schizophrenia
Ling Zou1, Luo Ouyang2, Xiao-Qi Huang1, Wei Deng1, Qin Chen1, Yi Wei1, Su Lui1, Hua-Fu Chen2, Tao Li1, Qi-Yong Gong1 1Huaxi Hospital, Sichuan University, Chengdu, People’s Republic of China; 2School of Science and Technology,University of Electronic Science and Technology of China, People’s Republic of China
2214. Single-Voxel Proton MRS at 1.5 Tesla Significantly Correlates with Hypofrontality in Schizophrenia
Jozef Dragašek1, Michal Bittšanský1, Peter Jankoviè1, Milena Drímalová1, Dušan Dobrota1 1Martin Faculty Hospital and Jessenius Medical Faculty, Comenius University, Martin, Slovakia
2215. Schizophrenia Patients Showed Impaired Hippocampal and Prefrontal Responses During Associative Learning: fMRI Evidence of Hypoactivation and Dysplasticity
Vaibhav A. Diwadkar1, 2, Saugata Chakraborty1, Eric Murphy1, Mark D. Benton3, Matcheri S. Keshavan1, 2 1Wayne State University SOM, Detroit, Michigan, USA; 2University of Pittsburgh SOM, Pittsburgh, Pennsylvania, USA; 3Northwestern University, Evanston, Illinois, USA
2216. Comparison of In Vivo MRI Methods for Examining White Matter Abnormalities in Schizophrenia
Bryon Alan Mueller1, Jeffrey R. Wozniak1, Ryan L. Muetzel1, Kelvin O. Lim1 1University of Minnesota, Minneapolis, Minnesota, USA
2217. The Integrity of Corpus Callosum and Cingulum in Schizophrenia Assessed by Diffusion Tensor Tractography
CHIH-JUI RAY CHEN1, HSIAO-LAN WANG1, SHI-KAI LIU2, Van J. WEDEEN3, TIMOTHY G. REESE3, WEN-YIH ISAAC TSENG1, 4 1Center for Optoelectronic Biomedicine, National Taiwan University College of Medicine, Taipei, Taiwan; 2Psychiatry Department, Far Eastern Memorial Hospital, Taipei, Taiwan; 3MGH Martinos Center for Biomedical Imaging, Harvard Medical School, Massachusetts, USA; 4Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan
2218. Amygdala Anisotropy Correlates with Aggression and Impulsivity
Jennifer Lynne Larsen1, 2, Ying Wu1, 2, Rene Ochs1, 2, Carly Demopoulos1, 2, Robert R. Edelman1, 2, Ann B. Ragin1, 2 1Northwestern University, Chicago, Illinois, USA; 2Evanston Northwestern Healthcare, Evanston, Illinois, USA
2219. Functional MRI Study of Negative Priming Implications for Frontal Disinhibition
Ngoc Jade Thai1, Tim L. Hodgson2, Pilar Andres3, Chiara Guerrini4 1Aston University, Birmingham, UK; 2Exeter University, Exeter, UK; 3Plymouth University, Plymouth, UK; 4Hull University, Hull, UK
2220.
Metabolic Alteration of the Dorsolateral Prefrontal Cortex in
Depressed Sprague-Dawley Rats by
Sung-Tak Hong1, Chi-Bong Choi2, Cheong-Soo Park3, Kwan-Soo Hong3, Bo-Young Choe2 1The Catholic University of Korea, Seoul, Seoul, Seocho-Gu, Republic of Korea; 2The Catholic University of Korea, Seoul, Seocho-Gu; 3Korea Basic Science Institute, Choong-Buk
2221. Amplitude of Low Frequency Fluctuation in Treatment Naive Schizophrenia Revealed by Resting-State Functional MRI
Hong Yang1, Wei Deng2, Tao Li2, Qi Hong Zou3, Xiang Ping Zhou, Yu Feng Zang1, 3, Qi Yong Gong1 1Huaxi MR Research Center (HMRRC),Department of Radiology, West China Hospital of Sichuan University, Chengdu, Sichuan, People’s Republic of China; 2Department of Clinical Psychiatry, West China Hospital of Sichuan University, Chengdu, Sichuan, People’s Republic of China; 3State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, People’s Republic of China
Epilepsy Imaging and Spectroscopy Hall 14.1 Wednesday 13:30 - 15:30
2222. Metabolic Networks in Temporal Lobe Epilepsy
Hoby Patrick Hetherington1, Ruben I. Kuzniecky2, Kenneth Vives1, Dennis D. Spencer1, Jullie W. Pan1 1Yale University, New Haven, Connecticut, USA; 2New York University, New York, New York, USA
2223. Hippocampal EEG Signal Complexity Correlates with NAA/Cr
Jullie W. Pan1, Hitten Zaveri1, Dennis D. Spencer1, Hoby P. Hetherington2 1Yale University School of Medicine, New Haven, Connecticut, USA; 2Albert Einstein College of Medicine, Bronx, New York, USA
2224.
Analysis of Multi-Site Structural Neuroimaging Data Using VBM:
A Case Study in Childhood
Heath Richard James Pardoe1, Gaby S. Pell1, David F. Abbott1, Anne T. Berg2, Graeme D. Jackson1 1Brain Research Institute, Melbourne, Victoria, Australia; 2University of Northern Illinois, DeKalb, Illinois, USA
2225. Single Subject Voxel-Based Analysis in Mesial Temporal Lobe Epilepsy
Heath Richard James Pardoe1, Gaby S. Pell1, Regula S. Briellmann1, Graeme D. Jackson1 1Brain Research Institute, Melbourne, Victoria, Australia
2226. Early Reductions in Diffusion Anisotropy Are Apparent in Pediatric Epilepsy
Elizabeth B. Hutchinson1, Alan B. McMillan1, Kevin Dabbs1, Bruce P. Hermann1, M Elizabeth Meyerand1 1University of Wisconsin, Madison, Wisconsin, USA
2227. Significance of Interictal Water Diffusion Changes in Frontal Lobe Epilepsy. Correlations with Stereo-Electro-EncephaloGraphy (SEEG)
Maxime Guye1, Jean-Philippe Ranjeva1, Fabrice Bartolomei1, Sylviane Confort-Gouny1, Patrick Chauvel1, Patrick J. Cozzone1 1Université de la Méditerranée, Marseille, France
2228. Highly Localized Alterations of White Matter in Fixation-Off Sensitivity: A Study Using DTI
Taryn Aprile1, Andrea Cherubini2, Carlo Di Bonaventura3, Anna Vaudano3, Anna Teresa Giallonardo3, Bruno Maraviglia4, 5, Gisela Elisabeth Hagberg1 1Santa Lucia Foundation, Rome, Italy; 2IRCCS S.Lucia, Rome, Italy; 3'La Sapienza' University, Rome, Italy; 4Enrico Fermi Centre, Rome, Italy; 5University of Rome 'La Sapienza', Rome, Italy
2229. Neuroabnormality of Thalamus in Secondarily Generalized Seizure: A Diffusion Tensor Study at 3T
Su Lui1, Luo Ouyang2, Qin Chen3, Xiao-qi Huang1, Shu-ying Zhang3, Wei Deng3, He-han Tang1, Hua-fu Chen2, Dong Zhou3, Qi-yong Gong1, 4 1West China Hospital of Sichuan University, Chengdu, Sichuan, People’s Republic of China; 2University of Electronic Science and Technology of China, Chengdu, Sichuan, People’s Republic of China; 3West China Hospital of Sichuan University, Sichuan, People’s Republic of China; 4University of Liverpool, Liverpool, UK
2230. Positive Default-Mode Activation in Epilepsy Using 2dTCA
Victoria L. Morgan1, Jerzy P. Szaflarski2, Bassel Abou-Khalil1, John C. Gore1 1Vanderbilt University, Nashville, Tennessee, USA; 2University of Cincinnati, Cincinnati, Ohio, USA
2231. Soluble Telencephalin is a Marker for Frontotemporal Dysfunction in Epilepsy as Revealed by fMRI
Jacobus FA Jansen1, Marielle CG Vlooswijk1, Mark H. de Baets1, Peter Rieckmann2, M Eline Kooi1, Albert P. Aldenkamp3, H.J. Marian Majoie3, Rianne P. Reijs4, Marc CTFM de Krom1, Paul AM Hofman1, Klaas Nicolay5, Walter H. Backes1 1Maastricht University Hospital, Maastricht, Netherlands; 2Julius-Maximilians University Hospital, Würzburg, Germany; 3Epilepsy Centre Kempenhaeghe, Heeze, Netherlands; 4Epilepsy Centre Kempenhaeghe, Heeze, Netherlands; 5Eindhoven University of Technology, Eindhoven, Netherlands
2232. Secondarily Generalized Seizures Induce a Functional Reorganization of Working Memory, as Demonstrated by fMRI
Jacobus FA Jansen1, Marielle CG Vlooswijk1, M Eline Kooi1, Albert P. Aldenkamp2, H.J. Marian Majoie2, Rianne P. Reijs3, Marc CTFM de Krom1, Paul AM Hofman1, Klaas Nicolay4, Walter H. Backes1 1Maastricht University Hospital, Maastricht, Netherlands; 2Epilepsy Centre Kempenhaeghe, Heeze, Netherlands; 3Epilepsy Centre Kempenhaeghe, Heeze, Netherlands; 4Eindhoven University of Technology, Eindhoven, Netherlands
2233. High-Resolution Imaging of Normal Human Hippocampus at 7 Tesla
Brenda F. Cuson-Reader1, Amir M. Abduljalil1, Georgeta Mihai1, Donald W. Chakeres1, Michael V. Knopp1, Petra Schmalbrock1 1The Ohio State University, Columbus, Ohio, USA
Hall 14.1 Wednesday 13:30 - 15:30
2234. Detecting Oligodendroglioma Genotype Non-Invasively Using MR Imaging
Robert A. Brown1, Magdalena Zlatescu1, 2, Peter Forsyth1, 2, Ian Parney1, 2, Robert Sevick1, Doug Demetrick1, David Schiff3, Gregory Cairncross1, 2, Ross Mitchell1 1University of Calgary, Calgary, AB, Canada; 2Southern Alberta Cancer Research Institute, Calgary, AB, Canada; 3University of Virginia, Charlottesville, Virginia, USA
2235. Perfusion Imaging of Brain Tumor Using Pulsed Arterial Spin Labeling: Correlation with Histopathological Blood Vessel Proliferation
Tomoyuki Noguchi1, Takashi Yoshiura1, Akio Hiwatashi1, Osamu Togao1, Koji Yamashita1, Sadahisa Shono, Masahiro Mizoguchi, Tomio Sasaki, Satoshi O. Suzuki, Toru Iwaki, Hiroshi Honda1 1Kyushu University, Fukuoka City, Fukuoka PRF, Japan
2236. Pre- And Postoperative MR Brain Imaging with Automatic Planning and Scanning Software in Tumor Patients: An Intraindividual Comparative Study at 3 Tesla
Michael Nelles1, Jürgen Gieseke1, 2, Horst Urbach1, Renate Bloemer1, Hans H. Schild1, Winfried A. Willinek1 1University of Bonn, Bonn, Germany; 2Philips Medical Systems, Best, Netherlands
2237. Assessment on Clinical Data of Nonlinear Stochastic Deconvolution Versus SVD and Block-Circulant SVD Methods for Quantitative DSC-MRI
Francesca Zanderigo1, Alessandra Bertoldo1, Denis Peruzzo1, Gianluigi Pillonetto1, Mirco Cosottini2, Claudio Cobelli1 1University of Padova, Padova, Italy; 2University of Pisa, Pisa, Italy
2238. Standardization Decreases Interpatient Differences in rCBV Measurements as a Function of Brain Tumor Grade
Devyani Bedekar1, Todd Jensen2, M Fishman1, Kevin Kvasnica1, Eric Paulson1, Melissa Wagnar-Schuman1, Doug Prah1, Kathleen Schmainda1 1Medical College of Wisconsin, Milwaukee, Wisconsin, USA; 2GE Healthcare, Waukesha, Wisconsin, USA
2239. A Multiparameter DSC Study Demonstrates the Best Predictor of Brain Tumor Grade
Melissa Lynne Wagner Schuman1, Devyani Bedekar1, Kevin Kvasnica1, Mathew Fishman1, Eric S. Paulson1, Scott D. Rand1, Hendrikus G.J. Krouwer1, Kathleen M. Schmainda1 1Medical College of Wisconsin, Milwaukee, Wisconsin, USA
2240. Fitting of the Piecewise Linear Function to Signal Intensity Time Curve and Its Application in Improving the Analysis of Concentration Time Curve of Dynamic Contrast Enhanced-MRI Data
Anup Singh1, RKS Rathore1, RK Gupta2, Mohammad Haris2, Divya KS Rathore1, Sanjay K. Verma1, Ankur Purwar1, Getaneh Bayu1, Manoj K. Sarma1, Jitesh K. Singh1 1IIT Kanpur, Kanpur, Uttar Pradesh, India; 2SGPGIMS, Lucknow, Uttar Pradesh, India
2241. Probing Microvascularity and Heterogeneity of Human Glioma Using Improved T1 Weighted Dynamic Contrast Enhanced MRI
Pauliah Mohan1, 2, Vipin Saxena2, Mohammad Haris1, Nuzhat Husain3, RKS Rathore4, Rakesh K. Gupta5 1Sanjay Gandhi Post Graduate Insitute of Medical Sciences, Lucknow, Uttar Pradesh, India; 2BBAU Central University, Lucknow, Uttar Pradesh, India; 3King George’s Medical University, Lucnow, Uttar Pradesh, India; 4Indian Institute of Technology, Kanpur, Uttar Pradesh, India; 5Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
2242. MR Based Radiation Therapy Treatment Planning on an Avanto/TIM System
Kiaran Patrick McGee1, Debora H. Brinkmann1, Kevin Johnson2, John I. Lane1, Robert L. Foote1, David R. DeLone1, Robert J. Witte1 1Mayo Clinic, Rochester, Minnesota, USA; 2Siemens Medical Systems, Malvin, Pennsylvania, USA
2243. Diffusion-Weighted Imaging and Apparent Diffusion Coefficient Values for Differentiation of Residual or Local Recurrent Tumor from Posttreatment/Postbiopsy Changes in Patients with Primary Head and Neck Squamous Cell Carcinoma
Jeong Hyun Lee1, Chang Woo Ryu2, Hyeon-Mi Yoo1, Hae Wook Pyun1, Sang Yoon Kim1, Deok Hee Lee1, Choong Gon Choi1, Sang Joon Kim1 1University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea; 2Kyung Hee University Medical College, East-West Neomedicine Hospital, Seoul, Republic of Korea
Hall 14.1 Wednesday 13:30 - 15:30
2244. Dual Voxel Two-Dimensional MR Spectroscopy of Hepatic Encephalopathy and Correlation with Neuropsychological Abnormalities
Michael Albert Thomas1, Virginia Elderkin-Thompson1, Nagarajan Rajakumar1, Sherry Liu1, Gaurav Verma1, Amir Huda2, Steve Han1, Rakesh K. Gupta1 1David Geffen School of Medicine at UCLA, Los Angeles, California, USA; 2California State University-Fresno, Fresno, California, USA
2245. Citrate in Pediatric CNS Tumors
Zachary A. Seymour1, Jonathan L. Finlay1, Ashok Panigrahy1, Marvin D. Nelson1, Stefan Bluml1, 2 1Childrens Hospital Los Angeles, Los Angeles, California, USA; 2Rudi Schulte Research Institute, Santa Barbara, California, USA
2246. A Multicentre Study of In Vivo 1HMRS of Paediatric Brain Stem Tumours
Lisa Maria Harris1, 2, Nigel P. Davies1, 2, Yu Sun1, 2, Kal Natarajan1, 2, Lesley MacPherson2, Spyros Sgouros, 12, Theo Arvanitis1, 2, Darren Hargrave3, 4, Sophie Riches3, 4, Geoffrey Payne3, 4, Martin Leach3, 4, Franklyn Howe5, Paul Morgan6, 7, Dorothee Auer6, 7, Tim Jaspan6, 7, Richard Grundy6, 7, Andrew C. Peet, 12 1University of Birmingham, Birmingham, UK; 2Birmingham Children's Hospital, Birmingham, UK; 3Royal Marsden Hospital, Sutton, UK; 4Institute of Cancer Research, Sutton, UK; 5St Georges Hospital Medical School, London, UK; 6Nottingham University, Nottingham, UK; 7Queen's Medical Centre, Nottingham, UK
2247. Correlation Between Choline Concentrations and Trace Values in Human Brain Tumors
Dita Wagnerova1, Filip Jiru1, Monika Dezortova1, Lydie Vargova2, Eva Sykova2, Milan Hajek1 1Institute for Clinical and Experimental Medicine, Prague, Czech Republic; 2Institute of Experimental Medicine, AS CR, Prague, Czech Republic
2248. 1H MRSI Study of Effects of Cognitive-Behavioral Therapy on Obsessive-Compulsive Disorder
Joseph O'Neill1, Eda Gorbis1, 2, Jamie Feusner1, Karron Maidment1, Jenny Yip2, Susanna Chang1, Noriko Salomon3, Sanjaya Saxena4 1UCLA Psychiatry, Los Angeles, California, USA; 2Westwood Institute, Los Angeles, California, USA; 3UCLA Radiological Sciences, Los Angeles, California, USA; 4UCSD Psychiatry, San Diego, California, USA
2249. Thalamic Involment in Painful and Painless Diabetic Neuropathy on H-MRS
Iain D. Wilkinson1, Rajiv A. Gandhi2, Dinesh Selvarajah2, Jefferson L. Marques2, Celia J. Emery2, Paul D. Griffiths1, Solomon Tesfaye2 1University of Sheffield, Sheffield, UK; 2Royal Hallamshire Hospital, Sheffield, UK
2250. Single Voxel Proton Resonance Spectroscopy as a Method for the Classification of Brain Tumors Using Artificial Neural Networks
Karin Liebenrodt1, Martin H J Busch1, Serban Mateiescu1, Hüseyin Sahinbas1, Jürgen Baier1, Peter Püttmann1, Dietrich H W Grönemeyer1 1Grönemeyer institute for microtherapy, Bochum, NRW, Germany
2251. GABA Changes Acutely in Human Brain After Nicotine Administration
Graeme F. Mason1, June Watzl1, Rosane Gomez1, Elizabeth Guidone, Gerard Sanacora, Tony George2, Peter Jatlow, Richard Kibbey, Gerald Shulman, 3, John H. Krystal, Douglas L. Rothman1, Stephanie O'Malley 1Yale University, New Haven, Connecticut, USA; 2University of Toronto, Toronto, Ontario, Canada; 3Howard Hughes Medical Institute,
2252. 1H MRS Detects Bilateral Abnormalities in Hippocampus of Temporal Lobe Epilepsy Patients
Jing Qi1, Dehang Wang1, Yonggang Lu1 1The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China
2253. 1H-MR Spectroscopy Utilizing a 1T Open MR System: Expanding Access to the Obese and Claustrophobic Patient Populations
Thomas G. Perkins1, Marijn Kruiskamp2, James Murdoch3, David Hitt1, William W. Orrison4 1Philips Medical Systems, Bothell, Washington, USA; 2Philips Medical Systems, Best, Netherlands; 3Philips Medical Systems, Cleveland, Ohio, USA; 4Amigenics & Nevada Imaging Centers, Las Vegas, Nevada, USA
2254. Quantitative MR Spectroscopy of Diffuse Intrinsic Brain Stem Glioma
Ashok Panigrahy1, Marvin D. Nelson1, Jonathan L. Finlay1, Stefan Bluml1, 2 1Childrens Hospital Los Angeles, Los Angeles, California, USA; 2Rudi Schulte Research Institute, Santa Barbara, California, USA
2255. Combining Voxel-Based Morphometry and 1H Magnetic Resonance Spectroscopy in Myotonic Dystrophy Type 2 and Type 1
Kolja Schiltz1, Joern Kaufmann, Heiko G. Niessen1, Stefan Vielhaber2 1University of Magdeburg, Magdeburg, Sachsen-Anhalt, Germany; 2Universitiy of Magdeburg, Magdeburg, Sachsen-Anhalt, Germany
2256. Differential Effects of Age on Tissue Water-Referenced Proton Metabolites in Basal Ganglia, Pons, and Cerebellum Using an MRS Sequence Optimized for Glutamate Detection
Natalie M. Zahr1, Dirk Mayer1, Adolf Pfefferbaum, 12, Edie V. Sullivan1 1Stanford University, Stanford, California, USA; 2SRI, Menlo Park, California, USA
2257. Frequency-Dependent Changes in Lactate Concentration During Activation of Human Visual Cortex
Ai-Ling Lin1, Jean Hardies1, Jia-Hong Gao2, Carrie S. Gregory1, Peter T. Fox1 1University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA; 2University of Chicago, Chicago, Illinois, USA
2258. Changes in Brain Energy Metabolism After Carotid Artery Stenting by In Vivo 31P NMR Spectroscopy
Sanjay Menon1, 2, Ulrich Pilatus1, Joerg Magerkurth1, Joachim Berkefeld1, Richard du Mesnil de Rochement1, F.E. Zanella1, Heinrich Lanfermann1 1University Hospital Frankfurt, Frankfurt, Germany; 2Krankenhaus Nordwest, Frankfurt, Germany
2259. Quantitative in-Vivo Brain Water Contents Measurements at 3.0T
Shannon Heather Kolind1, Burkhard Mädler2, Irene Margaret Vavasour1, Corree Laule1, Eugene Yip1, Alex L. MacKay1 1University of British Columbia, Vancouver, BC, Canada; 2University of British Columbia Hospital, Vancouver, BC, Canada
2260. Combined Volumetric MRI and MR Spectroscopic Analyses of the Cerebellum in Developmental Dyslexia
Suzanna Kim Laycock1, Roderick Iain Nicolson, Lauren I. Wallis, Gail Darwent, Sarah H. Wonders, Angela J. Fawcett, Paul D. Griffiths, Iain D. Wilkinson 1University of Sheffield, Sheffield, South Yorkshire, UK
2261. Brain MRSI Metabolic Study of Patients with Remethylation Deficiency
Abdesslem Khiat1, François-Guillaume Debray2, Marie Lambert2, Yvan Boulanger1 1Centre hospitalier de l’Université de Montréal, Montréal, Québec, Canada; 2Centre hospitalier universitaire Sainte-Justine, Montréal, Québec, Canada
2262. Cerebrospinal Fluid Lactate in P. Falciparum Malaria: Measurement by Chemical Shift Imaging at 3 Tesla
Christina Louise Tosti1, Esben Thade Petersen2, Jiraporn Laothamatas3, Xavier Golay4, Srirama Venkatraman Swaminathan5, Marc Van Cauteren6, James Murdoch5, Varinee Lekprasert3, Noppadon Tangpukdee3, Srivicha Krudsood3, Wattana Leowattana3, Polrat Wilairatana3, Robert L. DeLaPaz1, Truman R. Brown1, S. Looareesuwan3, Gary M. Brittenham1 1Columbia University, New York, New York, USA; 2National Neuroscience Institute, Singapore, Singapore; 3Mahidol University, Bangkok, Thailand; 4Singapore Bioimaging Consortium, Singapore, Singapore; 5Philips Medical Systems, Cleveland, Ohio, USA; 6Philips Medical Systems Asia Pacific, Tokyo, Japan
2263. A Study of Cerebral Energetics and pHi in the Visual Cortex Using 31P MRS During Stimulation of Reduced Blood Oxygen Saturation Levels
Rishma Vidyasagar1, Risto Kauppinen2 1University of Birmingham, Birmingham, UK; 2University of Birmingham, Birmingham
2264. MR Spectroscopy of Pituitary Macroadenomas for Preoperative Assessment of Proliferation and Hemorrhage
Andreas Stadlbauer1, 2, Christopher Nimsky1, Katja Pinker3, Stephan Gruber3, Erich Salomonowitz2, Michael Buchfelder1, Oliver Ganslandt1 1University of Erlangen-Nuremberg, Erlangen, Germany; 2Landesklinikum St. Poelten, St. Poelten, Austria; 3Medical University of Vienna, Vienna, Austria
MRI Studies of BBB Permeability Hall 14.1 Wednesday 13:30 - 15:30
2265. Non-Invasive Generation and Monitoring of Ultrasound-Induced Blood-Brain Barrier Opening in the Murine Hippocampus
James J. Choi1, Scott A. Small1, Truman R. Brown1, Elisa E. Konofagou1 1Columbia University, New York, New York, USA
2266. Quantitative Evaluation of BBB Blocking Property of BB1101 Using MRI
Saeid Taheri1, Eduardo Candillario-Jalil1, Eduardo Estrada2, Gary Rosenberg2, Rohit Sood1 1University of New Mexico, Albuquerque, New Mexico, USA; 2UNM, New Mexico
2267. Quantitative Evaluation of the Effect of Propylene Glycol on BBB Permeability
Rohit Sood1, Saeid Taheri2, Eduardo Estrada2, Gary Rosenberg2 1University of New Mexico, Albuquerque, New Mexico, USA; 2UNM, New Mexico
2268. Dynamic Diffusion Process of MRI Contrast Agents Into the Brain Following Blood-Brain Barrier Disruption
Marie Blanchette1, Luc Tremblay1, David Fortin1, Martin Lepage1 1Université de Sherbrooke, Sherbrooke, QC, Canada
2269. Contrast-Enhanced MRI of Blood-Brain Barrier Disruption in CCL2 Transgenic Mice During Pertussis Toxin-Induced Inflammation
Angela E. Schellenberg1, Richard Buist1, Henrik Toft-Hansen2, Trevor Owens2, James Peeling1 1University of Manitoba, Winnipeg, Manitoba, Canada; 2University of Southern Denmark, Odense, Denmark
Hall 14.1 Wednesday 13:30 - 15:30
2270. Verification of CSF-Based HARM in Acute Stroke Patients with Early Blood-Brain Barrier Disruption
Erica C. Henning1, Lawrence L. Latour1, Steven Warach1 1National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA
2271. Anterograde and Retrograde Degeneration of White Matter Tracts Following Stroke
Zohar Ben-Moshe1, Michal Kafri1, Natan Borenstein2, Irena Bova2, Yaniv Assaf1 1Tel Aviv University, Tel Aviv, Israel; 2Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
2272. Distribution and Progression of Cerebral White Matter Hyper-Intensities Per Flow Territories in a Large Population of Elderly Subjects
Enrico Arkink1, Nicole Schmidtz1, Roald van der Landen1, Mark A. van Buchem1, J H. Reiber1, Faiza Admiraal-Behloul1 1Leiden University Medical Center, Leiden, Netherlands
2273. Application of Geometrical Diffusion Tensor Imaging on Acute Ischemic Cerebral Infarction
Chun-Jung Juan1, 2, Yi-Jui Liu3, Ming-Chung Chou1, 2, Chao-Ying Wang1, 2, Hua-San Liu1, 2, Te-Cheng Lai3, Tzung-Tzuo Tsai3, Teng-Yi Huang4, Hsiao-Wen Chung1, 2, Cheng-Yu Chen2 1National Taiwan University, Taipei, Taiwan; 2Tri-Service General Hospital, Taipei, Taiwan; 3Feng Chia University, Taichung, Taiwan; 4National Taiwan University of Science and Technology, Taipei, Taiwan
2274. Reliability of Mismatch Measurement Methods
Marie Luby1, Steven Warach1 1National Institutes of Health, Bethesda, Maryland, USA
2275. Information Extraction from Ischemic Stroke MR Images Using Independent Component Analysis Technique
Siamak Pourabdollah-Nejad1, 2, Hassan Bagher-Ebadian1, Quan Jiang1, 3, Douglas C. Noll2, Daniel C. Alexander4, James R. Ewing1, 3, Kourosh Jafari-Khouzani1, Michael Chopp1, 3 1Henry Ford Health Sciences Center, Detroit, Michigan, USA; 2University of Michigan, Ann Arbor, Michigan, USA; 3Oakland University, Rochester, Michigan, USA; 4University College, London, UK
2276. Using Principal Component Analysis and Generalized Linear Models to Predict Final Outcome in Acute Stroke
Kristjana Ýr Jónsdóttir1, Leif Østergaard2, Kim Mouridsen2 1Aarhus University Hospital, Århus, Denmark; 2Aarhus University Hospital, Århus, Denmark
2277. Applying Data Mining for the Characterization of Acute Stroke
Mathijs Visser1, 2, Ronald Holthuizen1, Frank Hoogenraad1, Arjan W. Simonetti1, Arianne v. Muiswinkel1, Lawrence L. Latour3, Calina Ciuhu4 1Philips Medical Systems, Best, Netherlands; 2Eindhoven University of Technology (TU/e), Eindhoven, Netherlands; 3National Institute of Neurological Disorders and Stroke (NINDS), Washington DC, USA; 4Philips Research, Eindhoven, Netherlands
Hall 14.1 Wednesday 13:30 - 15:30
2278. Time Resolved TWIST MR Angiography of the Head and Neck:
Roya S. Saleh1, 2, Stefan G. Ruehm2, John Paul Finn2, Gerhard Laub3 1UCLA, Los Angeles, California, USA; 2University of California Los Angeles, Los Angeles, California, USA; 3Siemens,
2279. Analysis of Wall Shear Stress of Carotid Bifurcation Using Time-Resolved Three-Dimensional Phase-Contrast MR Imaging
Shuhei Yamashita1, Haruo Isoda1, Hiroyasu Takeda1, Yasuhide Okura2, Taro Seo2, Takashi Kosugi2, Hatsuko Nasu1, Shoichi Inagawa1, Yasuo Takehara1, Masaya Hirano3, Atsushi Nozaki3, Kiyoshi Nagasawa3, Marcus T. Alley4, Roland Bammer4, Hiroki Namba1, Harumi Sakahara1 1Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan; 2Renaissance of Technology Corporation, Hamamatsu, Shizuoka, Japan; 3GE Yokogawa Medical Systems, Hino, Tokyo, Japan; 4Stanford University School of Medicine, Stanford, California, USA
2280.
Assessment of Cerebral Metabolic Change in Patients
Undergoing Carotid Endarterectomy
Takashi Inoue1, Kuniaki Ogasawara1, Masakazu Kobayashi1, Hideaki Nishimoto1, Ryonoshin Hirooka1, Yoshiyuki Kanbara1, Yutaka Matsumura1, Shunrou Fujiwara2, Akira Ogawa1 1Iwate Medical University, Morioka, Iwate, Japan; 2Iwate Medical University, Morioka, Iwa, Japan
2281.
Comparison Between 2D and 3D Black Blood Imaging of the
Clinically Significant
Niranjan Balu1, Baocheng Chu1, Thomas Hatsukami1, Chun Yuan1, Vasily L. Yarnykh1 1University of Washington, Seattle, Washington, USA
2282. Longitudinal 2D Stresses in Carotid Plaques Using MRI-Based Fluid Structure Interaction Models
Samuel Alberg Kock1, Jens Vinge Nygaard2, Ernst Torben Fründ3, Erling Falk3, William Paaske3, Won Yong Kim3 1Aarhus University Hospital, Aarhus, Denmark; 2Aarhus University, Denmark; 3Aarhus University Hospital, Denmark
2283. Vascular Space Occupancy (VASO) MRI Demonstrates Changes in Cerebral Blood Volume in Internal Carotid Artery Stenosis Patients After Carotid Revascularization
Manus Joseph Donahue1, Peter Jan van Laar2, Peter van Zijl3, 4, Robert Stevens1, Jeroen Hendrikse2 1The Johns Hopkins School of Medicine, Baltimore, Maryland, USA; 2University Medical Center Utrecht, Utrecht, Netherlands; 3The, Baltimore, Maryland, USA; 4Kennedy Krieger Institute, Baltimore, Maryland, USA
2284. White Matter Hyperintensities and Balance Control in Elderly People with Diabetes and Hypertension
Mareile Haertle1, Peng Zhao1, Kun Hu1, Peter Novak2, Sarah LaRose1, David Alsop1, Vera Novak1 1Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA; 2Boston University, Boston, Massachusetts, USA
2285. The Value of Diffusion and Perfusion MRI of the Brain in Comatose Patients Treated with Mild Hypothermia After Cardiac Arrest
Hanna Sofia Järnum1, Linda Knutsson2, Malin Rundgren2, Roger Siemund2, Elisabet Englund2, Hans Friberg2, Elna-Marie Larsson1 1Aalborg Hospital, Aalborg, Denmark; 2Lund University Hospital, Sweden
2286. Follow-Up After Endovascular Therapy of Cerebral Aneurysms: A Comparative Study of Angiographic CT Versus Time-Of-Flight MR-Angiography at 1.5 and 3 Tesla
Jan-Hendrik Buhk1, Stefanie Leise1, Kai Kallenberg1, Alexander Mohr1, Peter Dechent1, Michael Knauth1 1University of Göttingen, Göttingen, Germany
2287. Evaluation of Intracranial Aneurysms with 3T TOF MRA: Compared to 64-MDCTA
Yoshiyasu Hiratsuka1, Hitoshi Miki1, Keiichi Kikuchi1, Ikuko Kiriyama1, Teruhito Mochizuki1, Shizue Takahashi2, Ichiro Matsubara2, Kazuhiko Sadamoto2 1Ehime University School of Medicine, Toon, Ehime, Japan; 2Washo-kai Sadamoto Hospital, Matsuyama, Ehime, Japan
Hall 14.1 Wednesday 13:30 - 15:30
2288.
Simultaneous and Quantitative Investigation of the Cerebral
Arterial and Venous Vasomotor
Yi-Jui Liu1, Chun-Jung Juan2, 3, Te-Cheng Lai1, Tsai-Tzung Tzuo1, Teng-Yi Huang4, Cheng-Wen Ko5, Meng-Hsueh Yu5, Cheng-Yu Chen2 1Feng Chia University, Taichung, Taiwan, Taiwan; 2Tri-Service General Hospital, Taipei, Taiwan, Taiwan; 3National Taiwan University, Taipei, Taiwan, Taiwan; 4National Taiwan University of Science and Technology, Taipei, Taiwan, Taiwan; 5National Sun Yat-sen University, Kaohsiung, Taiwan, Taiwan
2289. Assessment of TOF- And CE- MRA in the Visualisation of Small Cerebral Vessel-Structures at 3.0 T
Ulrike Wiesspeiner1, Rudolf Stollberger1, Klaus Leber1, Franz Ebner1 1Medical University of Graz, Graz, Austria
2290. To TOF or Not to TOF; Nonenhanced MRA at 7T
Stefan Maderwald1, 2, Jens M. Theysohn1, 2, Oliver Kraff, 12, Susanne C. Ladd, 12, Mark E. Ladd, 12, Karsten Wicklow3, Harald H. Quick, 12, Elke R. Gizewski2 1University Duisburg-Essen, Essen, Germany; 2University Hospital Essen, Essen, Germany; 3Siemens Medical Solutions, Erlangen, Germany
2291. Time-Resolved 3D Quantitative Flow MRI of the Major Intracranial Arteries
Roland Bammer1, Tom Hope1, Marcus T. Alley1 1Stanford University, Stanford, California, USA
2292.
Contrast Enhanced MR Angiography in Intracranial Arterial
Stenosis Reveals Collateral Circulation
Zhen Wu1, 2, Jianping Dai, Ewalt Mark Haacke, 13 1McMaster University, Hamilton, Ontario, Canada; 2Beijing Tiantan Hospital, Beijing, People’s Republic of China; 3Wayne State University, Detroit, Michigan, USA
2293. High Resolution MRA, Imaging M4 and Beyond
Samuel Barnes1, 2, E. Mark Haacke1, 2, Zahid Latif2 1Wayne State University, Detroit, Michigan, USA; 2The MRI Institute for Biomedical Research, Detroit, Michigan, USA
2294.
Time Resolved MRA of Intracranial AVM Patients at 3.0 Tesla:
Assessment of Circulation and
Roya Saleh1, Pablo Villabelanca1, Derek Lohan2, Andik Thomasian2, John Paul Finn1 1University of California Los Angeles, Los Angeles, California, USA; 2University of California Los Angeles, California
Hall 14.1 Wednesday 13:30 - 15:30
2295. The Clinical Value of Veno-BOLD on Vascular Malformations at 3.0T
Saying Li1, Rui Wang1, Min Chen1 1Beijing Hospital, Beijing, People’s Republic of China
2296.
Six-Fold 2D-SENSE Accelerated Intracranial Contrast-Enhanced
MR Venography -
Houchun Harry Hu1, Clifton R. Haider2, John Huston III2, Norbert G. Campeau2, Stephen J. Riederer2 1University of Southern California, Los Angeles, California, USA; 2Mayo Clinic College of Medicine, Rochester, Minnesota, USA
2297. Use of 4D-TRAK for Contrast-Enhanced Dynamic MR Venography of the Head
Marko K. Ivancevic1, Hemant Parmar2, Suresh Mukherji2, Nancy Dudek2, Romhild Hoogeveen3, Thomas L. Chenevert2 1Philips Medical Systems, Cleveland, Ohio, USA; 2University of Michigan Health System, Ann Arbor, Michigan, USA; 3Philips Medical Systems, Best, Netherlands
2298.
Optimization and Application of Simultaneous Triple Contrast,
T1, Arterial TOF and BOLD
Petra Schmalbrock1, Johannes T. Heverhagen1, Donald W. Chakeres1, Hee Chun1, Peter A. Wassenaar1, Georgeta Mihai1, Amir M. Abduljalil1, Steffen Sammet1, Regina Maria Koch1, John Duraj2, Michael V. Knopp1 1The Ohio State University, Columbus, Ohio, USA; 2Philips Medical Systems, Cleveland, Ohio, USA
2299. Clinical Application of Susceptibility Weighted Imaging (SWI) in Cerebrovascular Disease
Wenzhen Zhu1 1Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, People’s Republic of China
2300.
Susceptibility Weighted Imaging (SWI) of Cerebral Blood
Oxygenation During
Yulin Ge1, E Mark Haacke2, Robert I. Grossman1 1New York University School of Medicine, New York City, New York, USA; 2Wayne State University, Detroit, Michigan
2301.
Improved Detection and Diagnosis of Sturge-Weber Syndrome
Using MR Susceptibility
Yingjian Yu1, Csaba Juhasz2, Zhifeng Kou2, Yang Xuan2, Zahid Latif2, Kohsuke Kudo2, Harry T. Chugani2, Mark E. Haacke1, 2, Jiani Hu2 1MRI Institute of Biomedical Research, Detroit, Michigan, USA; 2Wayne State University, Detroit, Michigan, USA
2302.
Susceptibility Weighted Imaging Reveals Unique Information in
Multiple-Sclerosis Lesions Using
E. Mark Haacke1, Malek I. Makki1, Madeswaran Selvan1, Zahid Latif1, James Garbern1, Jiani Hu1, Meng Law2, Yulin Ge2 1Wayne State University, Detroit, Michigan, USA; 2New York University, New York, New York, USA
Hall 14.1 Wednesday 13:30 - 15:30
2303. Development of a MRI Phantom to Emulate the Relaxation Times of the Neonatal Brain at 3 Tesla
Timothy Neil Orr1, 2, Neil Gelman1, 2, Jeff Winter1, 2, Gordon Campbell, 23, Robert Terry Thompson1, 2 1Lawson Health Research Institute, London, Ontario, Canada; 2University of Western Ontario, London, Ontario, Canada; 3National Research Council Canada, London, Ontario, Canada
2304.
Transport in the Preterm Infant Brain: Quantitative Analysis
of the Relative Roles of Pulsatile Flow
Gary P. Zientara1, Janet S. Soul2, Katie E. McCann3, Adre du Plessis2, Haim Bassan2, Richard L. Robertson Jr. 2, Stephan E. Maier1, Ferenc A. Jolesz1, Lawrence P. Panych1, Steven A. Ringer1 1Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA; 2Children's Hospital Boston, Boston, Massachusetts, USA; 3Northeastern University, Boston, Massachusetts, USA
2305. Quantitative Relationships Between Brain-Water T2 and ADC at Term in Infants Born Prematurely
Enrico De Vita1, 2, Cornelia Franziska Hagmann2, Alan Bainbridge1, Basil Andrew Kapetanakis2, Rosarie Lombard1, Nicola J. Robertson2, Ernest B. Cady1, 2 1University College London Hospitals NHS Foundation Trust, London, UK; 2University College London, London, UK
2306. DTI Evidence of Persistence of the Ventricular Zone in Human Preterm Infants
Amit Malhotra1, Terrie E. Inder1, Adrian Epstein1, G. Larrry Bretthorst1, Joshua S. Shimony1, Amit Mathur1, Avi Synder1, Jeffrey J. Neil1 1Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA
2307.
Delayed Maturation of the Cortico-Spinal Tract of Premature
Newborns: A Preliminary
Jessica Dubois1, Francois Lazeyras1, Muriel Perrin2, Yann Cointepas2, Cristina Borradori-Tolsa1, Stephane Sizonenko1, Petra Huppi1 1Geneva University Hospitals, Geneva, Switzerland; 2CEA, Orsay, France
2308. Longitudinal fMRI and DTI Study of Brain Development in Preterm Newborns
Paola Scifo1, Cristina Baldoli1, Valeria Blasi1, Silvia Pontesilli1, Roberta Scotti1, Giuseppe Scotti1, Ferruccio Fazio1 1San Raffaele Scientific Institute, Milan, Italy
2309.
Probing the Blood/Brain Barrier in Neonates: 1H-MR
Spectroscopy Shows Low Protection Against
Roland Kreis1, Karin Zwygart1, Chris Boesch1, Joachim Pietz2, Jean-Marc Nuoffer3 1University Berne, Berne, Switzerland; 2University Heidelberg, Heidelberg, Germany; 3University Children's Hospital Berne, Berne, Switzerland
2310.
About the Use of Perfusion-Weighted Magnetic Resonance
Imaging to Define Patterns of
Pia Wintermark1, Nicola J. Robertson2, Adrien C. Moessinger1, Enrico De Vita, François Gudinchet3, Reto Meuli3 1CHUV, Lausanne, Vaud, Switzerland; 2Institute for Women's Health, University College London, London, UK; 3CHUV, Lausanne, Switzerland
2311. Is the Ventouse Responsible for Subdural and Extra Cranial Neonatal Hemorrhages?
Lauren Ingrid Wallis1, Paul David Griffiths1, Michael F. Smith2, Norman P. Davies3, Martyn N. Paley1, Elspeth Helen Whitby1 1The University of Sheffield, Sheffield, UK; 2Royal Hallamshire Hospital, Sheffield, UK; 3Mayo Clinic, Rochester, Minnesota, USA
Hall 14.1 Wednesday 13:30 - 15:30
2312. Diffusion Tensor Imaging in Mild and Moderate Pediatric Traumatic Brain Injury
Jeffrey Wozniak1, Linda Krach2, Erin Ward1, Bryon Mueller1, Ryan Muetzel1, Sarah Schnoebelen3, Nick Davenport1, Kelvin Lim1 1University of Minnesota, Minneapolis, Minnesota, USA; 2Gillette Children's Specialty Healthcare, St. Paul, Minnesota, USA; 3Children's Medical Center, Dallas, Texas, USA
2313. Acute Effects of Brain Radiation in Children Evaluated by Diffusion Tensor Imaging
Firouzeh Tannazi1, Todd McNutt1, Siamak Ardekani2, Larry J. Brant3, David Bonekamp1, Ori Shokek1, Kenneth Cohen1, Moody Wharam1, Susumu Mori1, Alena Horska1 1Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; 2Johns Hopkins University, Baltimore, Maryland, USA; 3NIH/NIA/GRC, Baltimore, Maryland, USA
2314. Exogenous Perfusion Imaging in Cortical Developmental Malformations
Iain D. Wilkinson1, Elisa Widjaja1, Nigel Hoggard1, Paul D. Griffiths1 1University of Sheffield, Sheffield, UK
2315.
Assymmetric Brain Development in Children with Sturge-Weber
Syndrome Demonstrated by
Matthew R. Amans1, 2, Zhifeng Kou2, Christopher Lai2, Otto Muzik2, Jiani Hu2, Harry T. Chugani2, Csaba Juhasz2 1St. Vincent's Catholic Medical Center, New York, New York, USA; 2Wayne State University, Detroit, Michigan, USA
Pediatric Psychiatric and Metabolic Disorders Hall 14.1 Wednesday 13:30 - 15:30
2316. Frontal Lobe Function: Association Between Neuropsychological Test Scores and N-Acetyl Aspartate
Alena Horska1, Mahaveer Degaonkar1, Melissa A. Matson2, Carolyn T. Wells3, E. Mark Mahone3 1Johns Hopkins University, Baltimore, Maryland, USA; 2University of Cincinnati School of Medicine, Ohio, USA; 3Kennedy Krieger Institute, Baltimore, Maryland, USA
2317. Using Diffusion Tensor Imaging to Assess White Matter Integrity in Subjects with Math Difficulties
Craig Lorang1, Lori Arlinghaus2, Nikki Davis2, John Gore2, Adam Anderson2 1Vanderbilt University, Nashville, Tennessee, USA; 2Vanderbilt University, Tennessee
2318. Structural Abnormalities of Adolescent Males with Attention-Deficit/Hyperactivity Disorder: A DTI Study
Kun-Hsien Chou1, Yuan-Hwa Chou2, Fang-Ying Chiu3, Wan-Yuo Gao4, Tung-Ping Su2, Woei-Chyn Chu1, Ching-Po Lin5 1Institute of Biomedical Engineering, National Yang-Ming University, Taipei, Taiwan; 2Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan; 3Institute of Radiological Sciences, National Yang-Ming University, Taipei, Taiwan; 4Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan; 5Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan
2319. Investigation by Means of Absolute Quantification of Proton MR Spectroscopy in Adolescent with Attention-Deficit/Hyperactive Disorder
Shih-Shan Dong1, Shang-Yueh Tsai2, Ping-Chen Yang3, Cheng-Yun Hsu1, Cheng-Wen Ko1, Ming-Ting Wu4, 5 1National Sun Yat-sen University, Kaohsiung, Taiwan; 2National Taiwan University, Taiwan; 3Kaohsiung Medical University, Kaohsiung, Taiwan; 4Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; 5National Yang Ming University, Taipei, Taiwan
2320. Accelerated Maturation of White Matter in Young Children with Autism: A High B Value DWI Study
Dafna Ben Bashat1, Vered Kronfeld-Duenias1, 2, Ditza A. Zachor3, Perla M. Ekstein1, Talma Hendler1, 2, Ricardo Tarrasch2, Ariela Even4, Yonata Levy4, 5, Liat Ben Sira1 1Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; 2Tel Aviv University, Tel Aviv, Israel; 3Assaf Harofe Medical Center, Tel Aviv, Israel; 4The Hebrew University, Jerusalem, Israel; 5Hadassah-Hebrew University, Jerusalem, Israel
2321. Cerebral Metabolic Deficits in Young Patients with Tourette Syndrome Assessed by Proton MRSI
Tim J. DeVito1, Dick J. Drost1, Richard W.J. Neufeld2, Nagalingam Rajakumar2, Peter C. Williamson, 12, Rob Nicolson, 12 1University of Western Ontario, Lawson Health Research Institute, London, Ontario, Canada; 2University of Western Ontario, London, Canada
2322. Investigating Williams Syndrome with Diffusion Tensor Imaging
Lori R. Arlinghaus1, Colin B. Compas1, Elisabeth M. Dykens1, Adam W. Anderson1 1Vanderbilt University, Nashville, Tennessee, USA
2323. Assessing Disease Severity in Late Infantile Neuronal Ceroid Lipofuscinosis Using Quantitative Magnetic Resonance Diffusion-Weighted Imaging
Jonathan P. Dyke1, Henning U. Voss1, Dolan Sondhi1, Neil R. Hackett1, Stefan Worgall1, Linda A. Heier1, Barry E. Kosofsky1, Aziz M. Ulug1, Dikoma C. Shungu1, Xiangling Mao1, Ronald G. Crystal1, Douglas Ballon1 1Weill Medical College of Cornell University, New York, USA
2324. Diffusion Tensor Imaging in Niemann-Pick C Disease on 3T
Christabel EC Lee1, David M. Thomasson1, Forbes D. Porter1, Andrea L. Gropman1, Nicole M. Yanjanin1, Eva H. Baker1 1National Institutes of Health, Bethesda, Maryland, USA
2325. Regional and Global Apparent Diffusion Coefficient in Inherited Prion Diseases: Correlation with Disease Severity
Harpreet Hyare1, Durre Siddique1, Tom Webb1, Steve Wroe1, John Collinge1, John Thornton1, Tarek Yousry1 1Institute of Neurology, London, UK
2326. The Usefulness of Proton MRS in Monitoring Ketogenic Diet Therapy in Mitochondrial Encephalopathy
Seung-Koo Lee1, Jinna Kim1, Eung Yeop Kim1 1Yonsei University College of Medicine, Seoul, Republic of Korea
2327.
An Autopsy Brain of Alexander Disease Studied by Comparison
of Histology with High Resolution
Matsuda Kant1, Tie-Qiang Li2, E Rushing3, M Quezado1, S Dodd4, H Merkle4, J Duyn4 1NCI, USA; 2NINDS, Bethesda, Maryland, USA; 3Armed Forces Institute of Pathology; 4NINDS, USA
2328.
Leukoencephalopathy with Brain Stem and Spinal Cord
Involvement and Elevated White
Steffi F. Dreha-Kulaczewski1, Peter Huppke1, Knut Brockmann1, Peter Dechent1, Gunther Helms1, Jürgen Finsterbusch2, Jens Frahm3, Jutta Gaertner1 1Georg August University, Goettingen, Germany; 2University Medical Center Hamburg-Eppendorf, Germany; 3Biomedizinische NMR Forschungs GmbH am MPI fuer biophysikalische Chemie, Goettingen, Germany
2329.
Correlation Between Brain Metabolites and Very Long Chain
Fatty Acid Levels in Asymptomatic
Michael J. Moser1, Gerald V. Raymond2, Hugo W. Moser2, Peter B. Barker1, 2 1Johns Hopkins University Sch of Med, Baltimore, Maryland, USA; 2Kennedy Krieger Insitute, Baltimore, Maryland, USA
Hall 14.1 Wednesday 13:30 - 15:30
2330. Measurement of T1 and T2 in the Cervical Spinal Cord at 3 Tesla
Seth Aaron Smith1, 2, Richard A.E. Edden1, 2, Peter B. Barker1, 2, Peter C.M. van Zijl1, 2 1Kennedy Krieger Institute, Baltimore, Maryland, USA; 2Johns Hopkins University, Baltimore, Maryland, USA
2331. 3D Myelin Water Imaging in the Spinal Cord at 3.0T
Erin Leigh MacMillan1, Burkhard Mädler2, Shannon Heather Kolind1, Eugene Yip1, Alex L. MacKay1 1University of British Columbia, Vancouver, BC, Canada; 2University of British Columbia Hospital, Vancouver, BC, Canada
2332. Quantitative MT (qMT) Characteristics of the Human Spinal Cord In Vivo
Seth Aaron Smith1, 2, Peter C.M. van Zijl1, 2, Gerald V. Raymond, 12, Hugo W. Moser, 12, Greg J. Stanisz3, 4 1Kennedy Krieger Institute, Baltimore, Maryland, USA; 2Johns Hopkins University, Baltimore, Maryland, USA; 3Sunnybrokk & Women's College Health Science Center, Toronto, Canada; 4University of Toronto, Toronto, Canada
2333.
Quantitative Cervical Proton Magnetic Resonance Spectroscopy
of Relapsing-Remitting
Anna Federica Marliani1, Valeria Clementi2, Luca Albini Riccioli1, Raffaele Agati1, Marco Leonardi1 1Bellaria Hospital, Bologna, Italy, Italy; 2GE Healthcare, Bologna, Italy, Italy
2334. Quantitative Cervical Proton Magnetic Resonance Spectroscopy of Multiple Sclerosis
Anna Federica Marliani1, Valeria Clementi2, Luca Albini Riccioli1, Raffaele Agati1, Marco Leonardi1 1Bellaria Hospital, Bologna, Italy, Italy; 2GE Healthcare, Bologna, Italy, Italy
2335.
A One Year Follow-Up Study of the Spinal Cord with Biplanar
MRI in Multiple Sclerosis –
Katrin Weier1, Yvonne Naegelin1, Alain Thoeni1, Jochen Hirsch1, Ludwig Kappos1, Ernst-Wilhelm Radue1, Achim Gass1 1University Hospital Basel, Basel, Switzerland
2336. Kinematic MR Imaging Using 3D FIESTA and Diffusion Tensor Imaging on an Open-Type MR Scanner
Masaaki Hori1, 2, Keiichi Ishigame2, Hiroshi Kumagai2, Kenji Suzuki3, Kenichi Kanda3, Hitoshi Terada4, Hisamoto Moriguchi1, Morio Shimada1, Eiichi Koda4, Tsutomu Araki2 1Toho University, Ota, Tokyo, Japan; 2University of Yamanashi, Chuo, Yamanashi, Japan; 3GE Healthcare, Japan; 4Toho University, Tokyo, Japan
2337.
The Combined Application of MRI and 3D Contrast Enhanced
Time-Resolved MRA in Detecting
Wen-zhen Zhu1 1Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, People’s Republic of China
2338.
Clinical Application Study of MR Perfusion Imaging and
Diffusion Tensor Imaging in the
Xiang Liu1, Wei Tian1, Yoshimitsu Ohgiya1, Sven Ekholm1, Per Lennart Westesson1 1University of Rochester Medical Center, Rochester, New York, USA
2339.
Initial Experience with Isotropic 3D-FSE-XETA (eXtended Echo
Train Acquisition) Imaging
David B. Hackney1, Reed Busse2, Nagamani Peri1, Ken Hwang3, Charles A. McKenzie1 1Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA; 2GE Healthcare, Waukesha, Wisconsin, USA; 3GE Healthcare, Houston, Texas, USA
2340. Consistent Automated Scan Planning of Spine
René Bergmans1, Chiel den Harder1, Arjan Willem Simonetti1, Vladimir Pekar2, Daniel Bystrov2, Rüdiger Grewer2, Arianne M C van Muiswinkel1 1Philips Medical Systems, Best, Netherlands; 2Philips Research Europe, Hamburg, Germany
Hall 14.1 Wednesday 13:30 - 15:30
2341. Spinal Cord Blood Flow (SCBF) Measurement by Arterial Spin Labeling (ASL)
Guillaume Duhamel1, Virginie Callot1, Patrick J. Cozzone1, Frank Kober1 1Faculté de Médecine de Marseille, Université de la Méditerranée, Marseille, France
2342. Multi-Layers Structure of Mouse Retina Detected Using T2 and ADC In Vivo
Qing Wang1, Junjie Chen2, Huiying Zhang3, Bruce A. Berkowitz4, Sheng-Kwei Song2 1Washington University in St.Louis, Sain Louis, Missouri, USA; 2Washington University in St. Louis, Saint Louis, Missouri, USA; 3Washington University, Saint Louis, Missouri, USA; 4Wayne State University School of Medicine, Detroit, Michigan, USA
2343. Magnetic Resonance Microscopy of Ex Vivo Mouse Brains: Contrast and Structure
Shuning Huang1, 2, Christina Liu2, Guangping Dai2, Bruce Rosen1, 2 1MIT, Cambridge, Massachusetts, USA; 2MGH, Charlestown, Massachusetts, USA
2344.
Morphological Difference Between In Vivo and Ex
Vivo Adult C57BL/6J Mouse Brain by
Yu Ma1, Bernd Foester2, Patrick Hof3, Scott Hamilton4, Smith David5, Yu Mei, Helene Benveniste 1Stony Brook University, Stony Brook, New York, USA; 2Phillips Inc., Brazil; 3Mount Sinai Shool of Medicine; 4Stony Brook University, New York; 5Brookhaven National Lab, New York
2345. High Field Imaging of Non-Human Primates: Anatomical Imaging and Relaxation Rates
L Martyn Klassen1, Ravi S. Menon1, 2 1Robarts Research Institute, London, Ontario, Canada; 2University of Western Ontario, London, Ontario, Canada
2346. The Developing Canine Brain: Characterization by MRS and DTI
Norman B. Konyer1, 2, Michael D. Noseworthy1, 3, Christina de Rivera4, Norton W. Milgram4, Howard Dobson2 1St. Joseph's Healthcare, Hamilton, Ontario, Canada; 2University of Guelph, Guelph, Ontario, Canada; 3McMaster University, Hamilton, Ontario, Canada; 4Cancog Technologies, Toronto, Ontario, Canada
2347. Chromium(VI)-Enhanced MRI of White Matter in Mouse Brain
Takashi Watanabe1, Jens Frahm1, Thomas Michaelis1 1Biomedizinische NMR Forschungs GmbH, Göttingen, Germany
2348. Relaxometry Study of Baboon Fetal Brains at 3T
Feng Liu1, 2, Marrianne Garland1, Raymond Stark1, Bradley S. Peterson1, 2, Yunsuo Duan1, 2, Alayar Kangarlu1, 2 1Columbia Universiy, New York, New York, USA; 2New York State Psychiatric Institute, New York, New York, USA
2349. Correlating In Vivo MRI with 3D Post Mortem Information in Rat Brain
Alexandre Guimond1, Albertine Dubois2, Anne-Sophie Hérard2, Philippe Méric3, Brigitte Gillet3, Thierry Delzescaux2 1Siemens Molecular Imaging, Oxford, UK; 2Commissariat à l'Energie Atomique, Orsay, France; 3CNRS-ICSN, Gif-sur-Yvette, France
2350.
Comparison of Spinal Vasculature in Mouse and Rat:
Investigations Using Magnetic
Mehmet Bilgen Bilgen1 1The University of Kansas Medical Center, Kansas City, Kansas, USA
2351.
High Temporal Resolution Measurements of Metabolic Water
Production from 17-Oxygen
Eric Albert Mellon1, Mallikarjunarao Kasam1, Reddy Shashank Beesam1, Santhosh R. Gaddam1, James E. Baumgardner2, Arijitt Borthakur1, Ravinder Reddy1 1University of Pennsylvania, Philadelphia, Pennsylvania, USA; 2Oscillogy LLC, Folsom, Pennsylvania, USA
2352. Monitoring Brain Dimpling and Intracortical Micro-Electrode Arrays with High Resolution MRI in Rats
Thomas Neuberger1, Kunal Paralikar, Xiaofeng Zhang1, Ryan S. Clement, Andrew Webb1 1Huck Institute Magnetic Resonance Centre, Penn State University, University Park, Pennsylvania, USA
2353. WITHDRAWN
2354. Near-Infrared Light Penetration in Rat Brain Modeled Using MRI Structural Information
Calvin L. Gerus1, Hamid Dehghani2, Kevin Forrester1, Jeff F. Dunn1 1University of Calgary, Calgary, AB, Canada; 2University of Exeter, Exeter, UK
2355. In Vivo Imaging of Nicotine-Exposed Adult Male Zebra Finches
Susanne L.T. Cappendijk1, John R. James2, Samuel Colles Grant3, 4 1College of Medicine, Tallahassee, Florida, USA; 2Virginia Commonwealth University, Richmond, Virginia, USA; 3The National High Magnetic Field Laboratory, Tallahassee, Florida, USA; 4The Florida State University, Tallahassee, Florida, USA
2356.
Feasibility Study of the Cerebrospinal Fluid Flow Circulation
in the Brain of Dogs with
Bilgin Keserci1, Akira Nakatani2, Yuji Hashiguchi1, Kumiko Iwai2, Hiroshi Taira3, Akihiko Maeda3, Tsuyoshi Matsuda1, Hasnine Akter Haque1, Kiyoshi Nagasawa1 1GE Healthcare, Tokyo, Japan; 2Nihon Medi-Physics Co. Ltd., Chiba, Japan; 3Taiyo Nippon Sanso Co., Tokyo, Japan
2357. Simultaneous Measurements of Ascorbic Acid and NAA in the Rat Brain In Vivo Using a Single-Shot, Two-Echo Selective Multiple Quantum Spectroscopy
In-Young Choi1, Sang-Pil Lee1 1University of Kansas Medical Center, Kansas City, Kansas, USA
2358.
In Vivo Brain 1H-MRS of Sodium Pentobarbital: A
Potential Index Reflecting Anesthesia
Fei Du1, Yi Zhang1, Xiao-Hong Zhu1, Wei Chen1 1University of Minnesota, Minneapolis, Minnesota, USA
2359. High Field (7 T) and Spatial Resolution (0.05 Ml Voxels) 3D MRSI in the Rhesus Macaque Brain
Songtao Liu1, Gadi Goelman2, Eva-Maria Ratai3, Margaret Lentz3, Sarah Pilkenton3, Ramon Gilberto Gonzalez3, Oded Gonen1 1New York University School of Medicine, New York, New York, USA; 2Hadassah Hebrew University Medical Center, Jerusalem, Israel; 3Massachusetts General Hospital, Charlestown, Massachusetts, USA
2360. Characterization of Age Induced Brain Changes Using MRI in Rats
Tamar Blumenfeld-Katzir1, Ofer Pasternak, Yaniv Assaf1 1Faculty of Life Sciences,Tel-Aviv University, Tel-Aviv, Israel
Hall 14.1 Wednesday 13:30 - 15:30
2361. Characterization of Metabolism in Rat Olfactory Bulb by In Vivo 1H and 1H-[13C] NMR
Golam M.I. Chowdhury1, Kvein L. Behar1, Douglas L. Rothman1, Robin A. de Graaf1 1Yale University, New Haven, Connecticut, USA
2362. Regional and Developmental Variation in Vitamin C Concentration in the Rat Brain Quantified In Vivo Using Short Echo-Time 1H MRS
Melissa Terpstra1, Raghavendra Rao1, Ivan Tkac1 1University of Minnesota, Minneapolis, Minnesota, USA
2363. In Vivo 13C MRS Using Very Low RF Power for Proton Decoupling
Shizhe Steve Li1, Jehoon Yang1, Jun Shen1 1NIH, Bethesda, Maryland, USA
2364. In Vivo Metabolite Differences Between the Basal Ganglia and Cerebellum of the Rat Brain Detected with Proton MRS at 3 T
Dirk Mayer1, Natalie M. Zahr1, Edith V. Sullivan1, Adolf Pfefferbaum1, 2 1Stanford University, Stanford, California, USA; 2SRI International, Menlo Park, California, USA
2365. Cerebral Metabolic Effect of Acute Inhibition of Aspartate Aminotransferase Measured by 1H MRS
Su Xu1, Wenjun Zhu1, Jun Shen1 1National Institute of Mental Health, Bethesda, Maryland, USA
MRS/MRI of Animal Trauma Models Hall 14.1 Wednesday 13:30 - 15:30
2366. Differential Cellular Metabolism Following Traumatic Brain Injury
Brenda Bartnik Olson1, David Hovda2, Richard Sutton2 1Loma Linda University, Loma Linda, California, USA; 2UCLA Brain Injury Research Center, Los Angeles, California, USA
2367. Is Glutamate or Glutamine Elevated Following Traumatic Brain Injury?
William Miles Brooks1, 2, Gregory Onyszchuk, In-Young Choi, Sang-Pil Lee, Crystal Bethel, Nancy E.J. Berman 1University of Kansas Medical Center, Kansas City, Kansas, USA; 2KUMC, Kansas City, Kansas, USA
2368. Monitoring Stem Cell Therapies of Spinal Cord Injury Using Quantitative T2 Relaxation
Greg Jan Stanisz1, Soheila Karimi-Abdolrezaee2, Nancy Lobaugh1, Wendy Oakden3, Voytek Gretka1, Eftekhar Efetkharpour2, Greg Hawryluk2, Jian Wang2, Michael Fehlings2 1Sunnybrook HSC, Toronto, Ontario, Canada; 2Toronto Western Hospital, Toronto, Ontario, Canada; 3University of Toronto, Toronto, Ontario, Canada
2369. Cervical Spinal Cord Injury in the Rat: Longitudinal MRI Comparison of Two Injury Severity Levels
Georgeta Mihai1, Yvette S. Nout1, C Amy Tovar1, Brandon A. Miller1, Petra Schmalbrock1, Jacqueline C. Bresnahan1, Michael S. Beattie1 1The Ohio State University, Columbus, Ohio, USA
2370. Quantitative MRI and MRS at Five to Eleven Months After Traumatic Brain Injury in Rat
Riikka Johanna Immonen1, Irina Kharatishvili1, Asla Pitkänen1, Juha-Pekka Niskanen1, Olli H.J. Gröhn1 1A. I. Virtanen Institute for Molecular Sciences, University of Kuopio, Kuopio, Finland
2371. In Vivo Visualization of Spinal Cord Injury in Experimental Mouse Model: A Feasibility Study on a Clinical 3.0 Tesla MR System
Ming Yang1, Zhen Guan1, Amir Abduljalil1, Gregory A. Christoforidis1, Phillip G. Popovich1, Jun Zhang1, Michael V. Knopp1 1The Ohio State University, Columbus, Ohio, USA
2372. A Simple, Robust, and Accurate Contusion Spinal Cord Injury Device for the Mouse Characterized by Diffusion MRI
Joong Kim1, Philip Bayly2, Sheng-Kwei Song1 1Washington University School of Medicine, St. Louis, Missouri, USA; 2Washington University, St. Louis, Missouri, USA
2373. ASL-MRI Assessment of the Effect of Hemorrhagic Shock on Cerebral Blood Flow After Experimental Traumatic Brain Injury in Mice
Lesley M. Foley1, A M. Dennis2, T Kevin Hitchens1, J A. Melick2, C Ho1, P M. Kochanek2 1Carnegie Mellon University, Pittsburgh, Pennsylvania, USA; 2University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
2374. Effect of iNOS on Cerebral Blood Flow After Head Trauma
Lesley M. Foley1, T Kevin Hitchens1, P M. Kochanek2, J A. Melick2, C Ho1 1Carnegie Mellon University, Pittsburgh, Pennsylvania, USA; 2University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
2375. Erythropoietin Protects from Posttraumatic Edema in the Rat Brain: MRI and Gravimetric Studies
Hana Lahrech1, 2, Yohan van de Looij1, 2, Olivier Verdonck1, 2, Gilles Francony1, 2, Olivier Carle1, 2, Régine Farion1, 2, Chantal Rémy1, 2, Christoph Segebarth1, 2, Jean-François Payen1, 2 1INSERM U594, Grenoble, France; 2Univ Joseph Fourier, Grenoble, France
2376. Longitudinal MRI of Spinal Cord Injury in Mouse: Changes in Signal Patterns Associated with the Inflammatory Response
Mehmet Bilgen Bilgen1 1The University of Kansas Medical Center, Kansas City, Kansas, USA
Hall 14.1 Wednesday 13:30 - 15:30
2377. QMT Is Specifically Sensitive to Myelin and Not Axonal Injury in Optic Nerve from Mice Undergoing Transient Retinal Ischemia
Xiawei Ou1, Shu-Wei Sun2, Daniel Frank Gochberg1, Sheng-Kwei Song2 1Vanderbilt University, Nashville, Tennessee, USA; 2Washington University School of Medicine, St. Louis, Missouri, USA
2378. Neurochemical Modulation in a Rat Model of Birth Asphyxia Detected by In Vivo Proton MRS
Todd Atwood1, April Ronca1, Gale Kleven1, Jian-Ming Zhu1 1Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
2379. Investigation of Metabolite Changes in Neonatal Rat Brain After Cerebral Hypoxia-Ischemia Using 1H-Spectroscopy at 9.4T
Nathalie Just1, 2, Nicolas Kunz2, Ingrid Kohler2, Petra S. Huppi3, Stephane V. Sizonenko3, Rolf Gruetter1, 2 1UNIL, Lausanne, Switzerland; 2CIBM/LIFMET, Lausanne, Switzerland; 3UNIGE, Geneva, Switzerland
2380. Intracellular pH After Perinatal Cerebral Hypoxia-Ischaemia Estimated from Nucleotide Triphosphate, Phosphoethanolamine, and Inorganic Phosphate Chemical Shifts
Ernest B. Cady1, Alan Bainbridge2, Ann Lorek3, Juliet Penrice3, Osuke Iwata3, John Wyatt3, Nicola J. Robertson3 1University College London Hospitals NHS Foundation Trust, London, UK; 2University London Hospitals NHS Foundation Trust, London, UK; 3University College London, London, UK
2381. MRI Assessment of Regional Cerebral Blood Flow After Asphyxial Cardiac Arrest in Immature Rats: A Preliminary Report
Lesley M. Foley1, M D. Manole2, T Kevin Hitchens1, H L. Alexander2, C Ho1, P M. Kochanek2, R S. Clark2 1Carnegie Mellon University, Pittsburgh, Pennsylvania, USA; 2University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
2382. Diffusion and Perfusion Changes During Long-Term Recovery After Prolonged Hypoxia
Nicole R. Brandon1, 2, Marc Uy1, 2, Renee Dallasen1, 2, Aaron Hirko1, Sachiko Jomura1, Yan Xu*1 1University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; 2 (equal contribution),
2383. Iron-Labeled Neural Stem Cell Homing After Neonatal Hypoxia-Ischemia
Andre Obenaus1, Stephan Ashwal1, Murat Digicaylioglu2, Beatrice Tone1, Amber Wang1, Hui Rou Tian1, Evan Snyder3 1Loma Linda University, Loma Linda, California, USA; 2University of California, San Diego, San Diego, California, USA; 3Burnham Institute, La Jolla, California, USA
2384. Temporal and Regional Evolution of Aquaporin 4 Expression and Magnetic Resonance Imaging in a Rat Pup Model of Neonatal Stroke
Andre Obenaus1, Stephan Ashwal1, Beatrice Tone1, Amber Wang1, L Regli2, Hui Rou Tian1, Jérôme Badaut2 1Loma Linda University, Loma Linda, California, USA; 2Centre hospitalier universitaire vaudois, Lausanne, Switzerland
2385. Quantitative Evaluation of Blood-Brain Barrier (BBB) Permeability Using Patlak Plots Methodology in a Model of Transient Focal Ischemia in Rats
Usama Abo Ramadan1, Aysan Durukan1, Miia Pitkonen1, Lauri Soinne1, Ivan Marinkovic1, Ertugrul Tatlisumak1, Eric pedrono1, Daniel Strbian1, Turgut Tatlisumak1 1Helsinki University Central Hospital, Helsinki, Finland
2386. Effect of Hypothyroidism in Metabolic Profile of Rats After Cerebral Ischemia/reperfusion: A 1H NMR Study
Leena Rastogi1, Syed Naved Akhtar2, Madan M. Godbole3 1Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India; 2Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India; 3Sanjay Gandhi Post Graduate Institute, Lucknow, Uttar Pradesh, India
2387.
Combining 31P-MRS with Near-Infrared Spectroscopy to Measure
the Concurrent Changes in
Jeff David Winter1, Kenneth M. Tichauer1, 2, Neil Gelman1, 2, R Terry Thompson1, 2, Ting Yim Lee1, 2, Keith St. Lawrence1, 2 1Lawson Health Research Institute, London, Ontario, Canada; 2University of Western Ontario, London, Ontario, Canada
2388. Temporal Profiles of the Infarct Frequency in Acute Stroke
Qiang Shen1, Hanh Nguyen1, Timothy Q. Duong1 1Emory Unviersity, Atlanta, Georgia, USA
2389. Direct Comparison of T2 and T2ρ Image Contrast in a Rat Model of Acute Cerebral Ischemia
Simona Nikolova1, Robert Bartha1, Miranda Bellyou1 1Robarts Research Institute, London, Ontario, Canada
2390. Quantification of Multicomponent T2 in Brain After Reversible Ischemia
Jeff F. Dunn1, Debora A. Kelly1, Cheryl McCreary1, Thorarin A. Bjarnason1, Zonghang Zhao1, Ross Mitchell1 1University of Calgary, Calgary, AB, Canada
2391. Temporal Assessment of Rat Brain Vasculature After Transient Focal Cerebral Ischemia
Chien-Yuan Lin1, 2, Jyh-Horng Chen1, Ming-Huang Lin2, Wai-Mui Cheung2, Teng-Nan Lin2, Chen Chang2 1Interdisciplinary MRI/MRS Lab, Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan; 2Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan
2392. How Long Does It Take Before ADC Reduction Becomes Irreversible?
Qiang Shen1, Erica Fletcher1, Timothy Q. Duong1 1Emory Unviersity, Atlanta, Georgia, USA
2393.
Simultaneous and Ultrafast Monitoring of CMRO2,
CBF and pO2 Changes in Response to
Xiao-Hong Zhu1, Yi Zhang1, Wei Chen1 1CMRR, Department of Radiology, University of Minnesota Medical School, Minneapolis, Minnesota, USA
2394.
Reperfusion-Based Hemorrhagic Transformation in Spontaneously
Hypertensive Rats:
Erica C. Henning1, Lawrence L. Latour1, John M. Hallenbeck1, Steven Warach1 1National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA
2395. In Vivo Assessment of Optic Nerve Degeneration in Glaucoma Rat Model Using Diffusion Tensor Imaging
Edward Sai Kam Hui1, Sheryle Q. Fu1, Kevin Chuen Wing Chan1, Kwok Fai So1, Ed Xuekui Wu1 1The University of Hong Kong, Pokfulam, Hong Kong
Neuro MRI of Genetic Animal Models Hall 14.1 Wednesday 13:30 - 15:30
2396.
Assessment of Neuronal Marker and Brain Iron in Aphakia Mice
Model for Parkinson’s Disease
Shalom Michaeli1, Terry Burns, Joseph Lin1, Michael Garwood1, Kamil Ugurbil1, Walter Low 1CMRR, University of Minnesota, Minneapolis, Minnesota, USA
2397. Comparative Response to Focal Cerebral Ischemia of C57Blj6, Trek-1-/- And Traak-/- Mice
Christophe Laigle1, Angèle Viola1, Sylviane Confort-Gouny1, Yann Le Fur1, Nicolas Guy2, Michel Lazdunski2, Catherine Heurteaux2, Patrick J Cozzone1 1Centre de Résonance Magnétique Biologique et Médicale, UMR CNRS 6612, Marseille, France; 2Institut de Pharmacologie Moléculaire et Cellulaire (I.P.M.C.), UMR 6097, C.N.R.S/U.N.S.A, Valbonne, France
2398. Prediction and Prevention of Encephalopathy in Mouse Model of Glutaric Acidemia
William J. Zinnanti1, Jelena Lazovic2, Keith C. Cheng1 1The Pennsylvania State University, Hershey, Pennsylvania, USA; 2California Institute of Technology, Pasadena, California, USA
2399. MRM of Perfused Alzheimer’s Mice Hippocampal Slices
Peter Tek1, Shadi F. Othman1, Osama M. Abdullah1, Orly Lazarov1, Christopher Fall1, Richard L. Magin1 1University of Illinois at Chicago, Chicago, Illinois, USA
2400.
MR Angiography Detects Cerebral Amyloid Angiopathy (CAA)
Associated with Alterations of
Nicolau Beckmann1, Estibaliz Capetillo-Zarate2, Sergey Larionov2, Matthias Staufenbiel1, Stefan Zurbruegg1, Dietmar R. Thal2 1Novartis Institutes for BioMedical Research, Basel, Switzerland; 2University of Bonn, Bonn, Germany
2401.
31P MRS Study of Brain Creatine Kinase in Two Different
Animal Models Simulating
Svatava Kasparova1, Ladislav Baciak1, Norbert Zilka2, Michal Novak2, Stefan Zbyn3, Jaromir Horecky4, Tibor Liptaj1 1Slovak University of Technology, Bratislava, Slovakia, Slovakia; 2Slovak Academy of Science, Bratislava, Slovakia, Slovakia; 3Medical University of Vienna, Viena, Austria, Austria; 4Slovak Medical University, Bratislava, Slovakia, Slovakia
2402.
Viscoelastic Properties of the Brain in High Field MR
Elastography - In-Vivo Application to
Queenie C.C. Chan1, Benoit Larrat2, Xi Fei Yang1, Geng Li1, Edward S. Yang1, Ralph Sinkus2 1The University of Hong Kong, Pokfulam, Hong Kong; 2Universitˆm Paris VII, France
2403. An Iterative, Non-Linear Mouse Atlas for Mouse Brain Phenotyping in a Huntington's Disease Model
Stephen John Sawiak1, Guy B. Williams1, Nigel I. Wood2, A J. Morton2, T Adrian Carpenter1 1University of Cambridge, Cambridge, England, UK; 2University of Cambridge, England, UK
2404.
Metabolic Fingerprints of Altered Brain Growth in a Rett
Syndrome Mouse Model :
Angèle Viola1, Véronique Saywell2, Laurent Villard2, Patrick J. Cozzone1, Norbert W. Lutz1 1Faculté de Médecine de Marseille, Université de la Méditerranée, Marseille, France; 2School of Medicine, Marseille, France
2405.
Metabolic Magnetic Resonance Progression Markers of
Neurodegeneration in the Transgenic
Heiko G. Niessen1, Grazyna Debska-Vielhaber1, Frank Angenstein1, Kerstin Sander2, Dieter Leibfritz3, Stefan Vielhaber1 1University of Magdeburg, Magdeburg, Germany; 2Leibniz-Institute for Neurobiology, Magdeburg, Germany; 3University of Bremen, Bremen, Germany
2406.
Detection of Structural and Functional Changes in the Cortex
of Bassoon-Mutant Mice by
Frank Angenstein1, 2, Heiko G. Niessen3, Juergen Goldschmidt1, Eckart D. Gundelfinger1, Liane Hilfert2, Werner Zuschratter1, Henning Scheich1 1Leibniz Institute for Neurobiology, Magdeburg, Germany; 2University of Magdeburg, Magdeburg, Germany; 3Boehringer Ingelheim Pharma GmbH & Co KG, Biberach, Germany
2407.
In Vivo Characterization of Brain Phenotypes Associated with
Two-Pore Domain K+ Channel
Christophe Laigle1, Sylviane Confort-Gouny1, Yann Le Fur1, Nicolas Guy2, Michel Lazdunski2, Catherine Heurteaux2, Patrick J Cozzone1, Angèle Viola1 1Centre de Résonance Magnétique Biologique et Médicale, UMR CNRS 6612, Marseille, France; 2Institut de Pharmacologie Moléculaire et Cellulaire (I.P.M.C.), UMR 6097, C.N.R.S/U.N.S.A, Valbonne, France
MRI/MRS of Animal Models of White Matter Disease Hall 14.1 Wednesday 13:30 - 15:30
2408. Serial Proton MRS Evaluation of Neurometabolism in a Mouse Model of Systemic Lupus Erythematosus (SLE)
Todd Atwood1, Nilamadhab Mishra1, Jian-Ming Zhu1 1Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA
2409.
Characterization of Neurodegeneration in Experimental
Autoimmune Encephalomyelitis
Edward Sai Kam Hui1, Bing Hu1, Kevin Chuen Wing Chan1, Sha Mi2, Kwok Fai So1, Wu Tian Wu1, Ed Xuekui Wu1 1The University of Hong Kong, Pokfulam, Hong Kong; 2Biogen Idec, Cambridge, MA 02142, USA
2410.
A Longitudinal Study of Myelin Oligodendryocyte Glycoprotein
(MOG)-Induced EAE Using
Vamsidhar Chavakula1, Blair Cardigan Smith2, Angela Schellenberg3, Richard Buist3, Daniel Procissi1, Scott E. Fraser1, Russell E. Jacobs1, Melanie Martin2, 3, Carol Readhead1 1Caltech, Pasadena, California, USA; 2University of Winnipeg, Winnipeg, Manitoba, Canada; 3University of Manitoba, Winnipeg, Manitoba, Canada
2411. Quantitative Magnetization Transfer Imaging of Focal EAE Lesions
Martin Rausch1, Pernilla Lervik1, Tim Seabrook1, Anna Schubart1, Paul S. Tofts2 1Novartis Institutes for BioMedical Research, Basel, Switzerland; 2Brighton and Sussex Medical School, Brighton, UK
2412.
Characterization of Myelin Damage in Multiple Sclerosis Using
Myelin Water Imaging:
Ives R. Levesque1, G. Bruce Pike1 1Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada
2413. USPIO Dynamics in an Animal Model of Multiple Sclerosis
Raoul David Oude Engberink1, Susanne van der Pol2, H E. de Vries2, Erwin L. Blezer1 1University Medical Center Utrecht, Utrecht, Netherlands; 2VU Medical Center, Amsterdam, Netherlands
2414. In Vivo MRI/MRS of PTEN-Null Mice - An Animal Model of Hypermyelination
Susann Boretius1, Sandra Goebbels2, Klaus-Armin Nave2, Jens Frahm1, Thomas Michaelis1 1Max-Planck-Institut fuer biophysikalische Chemie, Goettingen, Germany; 2Max-Planck-Institut fuer experimentelle Medizin, Goettingen, Germany
MRI/MRS of Animal Neuro Models: Other Hall 14.1 Wednesday 13:30 - 15:30
2415.
Regional Metabolic Abnormalities as a Function of Age in
Familial Amyotrophic Lateral
Ji-Kyung Choi1, Alpaslan Dedeoglu2, Bruce G. Jenkins3 1MGH-NMR Center and Matinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA; 2VA Medical Center, Bedford, Massachusetts, USA; 3MGH-NMR Center and Martinos Center for Biomedical Imaging,
2416. Evolution of Mice Brain Metabolism After a Convulsive Dose of Soman : A HRMAS 1H-NMR Study
Florence Fauvelle1, Guy Testylier1, Herald Rabeson2, Danielle Graveron-demilly2, Annie Foquin1, Pierre Carpentier1, Frédéric dorandeu1 1CRSSA, La Tronche, France; 2Université Lyon1, Villeurbanne, France
2417. Diffusion in the Rat Cerebral Cortex During Pilocarpine-Induced Status Epilepticus
Ivan Vorisek1, 2, Karel Slais1, Lesia Dmytrenko1, Eva Sykova1, 2 1Institute of Experimental Medicine ASCR, Prague, Czech Republic; 2Charles University, 2nd Medical Faculty, Prague, Czech Republic
2418.
MR Measurements of Diffusion, Perfusion and T2 with Proteomic
Analysis in the
ManKin Choy1, Rodney C. Scott1, David L. Thomas2, David G. Gadian1, Nicholas Greene1, Robin Wait3, Kit-Yi Leung4, Mark F. Lythgoe1 1UCL Institute of Child Health, London, UK; 2UCL, London, UK; 3Imperial College Schhol of Science, Technology and Medicine, London, UK; 4Bart's and the London, London, UK
2419. Prospective Brain T2 Relaxometry and Diffusion Tensor Imaging in a Rat Model of Early-Life Febrile Convulsions
Jacobus FA Jansen1, 2, Evi P. Lemmens1, Govert Hoogland1, Olaf E. Schijns1, Ward Jennekens2, Gustav J. Strijkers2, Jeanine J. Prompers2, Jo W. Habets2, M Eline Kooi1, Walter H. Backes1, Klaas Nicolay2 1Maastricht University Hospital, Maastricht, Netherlands; 2Eindhoven University of Technology, Eindhoven, Netherlands
2420. Infection with Plasmodium Berghei ANKA Leads to Brain Damage in Mice Resistant to Cerebral Malaria
Marie-France Penet1, Frank Kober1, Sylviane Confort-Gouny1, Yann Le Fur1, Christiane Dalmasso1, Nicolas Coltel2, Agnès Liprandi3, Jean-Marc Gulian3, Georges E Grau4, Patrick J Cozzone1, Angèle Viola1 1Centre de Résonance Magnétique Biologique et Médicale, UMR CNRS 6612, Marseille, France; 2UMR CNRS 6020, Marseille, France; 3Hôpital la Timone, Marseille, Marseille, France; 4The University of Sydney, Sydney, Australia
2421. Effect of Diet and Exercise on MR Outcomes of a Model of Vascular Dementia in Aged Rats
Richard Buist1, Kathy McKay2, Garry Chernenko2, Dale Corbett2, James Peeling1 1University of Manitoba, Winnipeg, Manitoba, Canada; 2Memorial University, St. John's, Newfoundland, Canada
2422. Neuroprotective Effects of Modafinil in a Nonhuman Primate Parkinson Model
Sanneke A.M. van Vliet1, 2, Erwin L.A. Blezer3, Marjan Jongsma1, Raymond A.P. van Wersch1, Ingrid H.C.H.M. Philippens1 1TNO Defense, security and safety, Rijswijk, Netherlands; 2Institute of Pharmaceutical Sciences and Rudolf Magnus Institute of Neurosciences, Utrecht, Netherlands; 3University Medical Center Utrecht, Utrecht, Netherlands
2423. Pathological Change in Nigrostriatal Pathway in MPTP Induced Parkinson's Disease Animal Model Using DTI and MRS
Yu-Ying Tung1, 2, Ching-Po Lin1, Chen Chang2 1Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan; 2Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan
2424. Neuroprotective Composition Effective for Ameliorating Mental Decline: Volume MR Image In Vivo
Geng Li1, Xi-Fei Yang1, Queenie CC Chan1, Gina J. Gu1, Edward S. Yang1 1The University of Hong Kong, HK, HKSAR, People’s Republic of China
2425.
Assessment of the Protective Effect of L-Carnitine in
Hepatic: Improvements of Muscle and
Claudia Zwingmann1, Sven Gottschalk1, Wenlei Jiang1, Roger Butterworth1, Dieter Leibfritz2 1Hospital Saint-Luc, Montreal, Quebec, Canada; 2University of Bremen, Bremen, Germany
2426.
Cocaine-Induced Cerebral ADC and Hemodynamic Changes Between
Cocaine-Naïve Rats and
Congwu Du1, 2, Yu Ma1, Mei Yu1, David S. Smith1, Zhongchi Luo1, 3, Helene Benveniste1, 2 1Brookhaven National Laboratory, Upton, New York, USA; 2State Univ of New York at Stony Brook, Stony Brook, New York, USA; 3State University of New York at Stony Brook, Stony Brook, New York, USA
2427. Cerebral Metabolism of Adult Marmoset Monkeys After Intrauterine Hyperexposure to Dexamethasone
Thomas Michaelis1, Alireza Abaei1, Roland Tammer1, Susann Boretius1, Cristina Schlumbohm2, Eberhard Fuchs2, Jens Frahm1 1Biomedizinische NMR Forschungs GmbH, Goettingen, Germany; 2Deutsches Primatenzentrum, Goettingen, Germany
Hall 14.1 Wednesday 13:30 - 15:30
2428.
Decreased Axial Diffusivity as a Biomarker of Axonal Injury
in the Spinal Cord White Matter of
Matthew D. Budde1, Joong Kim, Mingqiang Xie, Ariel Liang, Anne H. Cross, Sheng-Kwei Song 1Washington University, St Louis, Missouri, USA
2429. High Temporal Resolution Diffusion MR Imaging of the Mouse Spinal Cord Using Echo Planar Imaging
Virginie Callot1, Guillaume Duhamel1, Patrick J. Cozzone1, Frank Kober1 1Centre de Résonance Magnétique Biologique et Médicale (CRMBM), Marseille, France
2430.
Acute Axial Diffusivity Changes Predict Long Term Locomotor
Function Recovery After Spinal
Qing Wang1, Joong Hee Kim1, David N. Loy2, Sheng-Kwei Song3 1Washington University in St.Louis, Saint Louis, Missouri, USA; 2Washington University in St. Louis, Saint Louis, Missouri, USA; 3Washington University in St. Louis, Saint Louis, Missouri, USA
2431. In Vivo MRI of Axonal Damage with Subtle Myelin Defects in PLP-Null Mice
Susann Boretius1, Sandra Goebbels2, Agnieszka Burzynska1, Roland Tammer1, Klaus-Armin Nave2, Jens Frahm1, Thomas Michaelis1 1Max-Planck-Institut fuer biophysikalische Chemie, Goettingen, Germany; 2Max-Planck-Institut fuer experimentelle Medizin, Goettingen, Germany
2432.
Temporal and Spatial Evolution of Wallerian Degeneration in
Central Nervous System
Shu-Wei Sun1, Anne H. Cross1, Sheng-Kwei Song1 1Washington University School of Medicine, St. Louis, Missouri, USA
2433. In Vivo Diffusion Kurtosis Imaging of Rat Brain
Edward Sai Kam Hui1, Hanzhang Lu2, Jens H. Jensen3, Joseph A. Helpern4, Kevin Chuen Wing Chan1, Ed Xuekui Wu1 1The University of Hong Kong, Pokfulam, Hong Kong; 2UT Southwestern Medical Centre, Dallas, TX 75390, USA; 3New York University School of Medicine, New York, USA; 4Centre for Biomedical Imaging, New York University, New York, USA
2434.
Diffusion Tensor Imaging of Spinal Cord Injury: Regional
Differences in White Matter
David Neil Loy1, Joong Hee Kim, Kathryn Trinkaus, Robert E. Schmidt, Sheng-Kwei Song2 1Washington University, Saint Louis, Missouri, USA; 2Washington University, S, Missouri
2435. White Matter Damage in Nijmegen Breakage Syndrome by Diffusion and T2 MRI
Yaniv Assaf1, Ronit Galron1, Itai Shapira1, Tamar Blumenfeld-Katzir1, Zhao-Qi Wang2, Yosef Shiloh1, Ari Barzilai1 1Tel Aviv University, Tel Aviv, Israel; 2Fritz Lipmann Institute, Jena, Germany
2436. Reversible Axonal Injury Detected by DTI and Immnohistochemistry
Hsiao-Fang Liang1, Shu-Wei Sun1, Pei-Ching Chang2, Chen Chang2, Anne H. Cross1, Sheng-Kwei Song1 1Washington University School of Medicine, St. Louis, Missouri, USA; 2Academia Sinica, Taipei, Taiwan, Taiwan
2437. In Vivo DTI Study of Developmental Rat Brain
Ho-fai Lau1, Edward Saikam Hui1, Hiu-fai Siu1, Jian Yang1, Pek-lan Khong1, Ed Xuekui Wu1 1The University of Hong Kong, Pokfulam, Hong Kong
Hall 14.1 Wednesday 13:30 - 15:30
2438. Visualization of Mouse Corticospinal Tract by Manganese-Enhanced Magnetic Resonance Imaging
Zhixin L. Huang1, Yong-Yue He1, Mehmet Bilgen1 1The University of Kansas Medical Center, Kansas City, Kansas, USA
2439.
Functional Imaging of Olfactory Neural Network In Vivo
Using Manganese Enhanced MRI:
Yoo Jeong Yim1, Hyun Jong Lee1, Hyung-Jin Kim1, Hun-Jong Dhong1, Seung Kyu Chung1, Keun-Ho Lim2, Ki-Soo Kim3, Jung Hee Lee1 1Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; 2Asan Institutes for Life Science, University of Ulsan, Seoul, Republic of Korea; 3Asan Medican Center, University of Ulsan, Seoul, Republic of Korea
2440.
Changes of Proton T1 and T2 Relaxation
Times of Cerebral Metabolites Induced by
Xuxia Wang1, Chaoni Xiao1, Hao Lei1 1Wuhan Institute of Physics & Mathematics, Chinese Academy of Science, Wuhan, Hubei, People’s Republic of China
2441. Quantitative Assessment of Axonal Transport Integrity in the Mouse Brain In Vivo Using MEMRI at 9.4 T
Sang-Pil Lee1 1University of Kansas Medical Center, Kansas City, Kansas, USA
2442. Manganese Enhanced MRI of Olfactory Pathway in Developing Rats
Waqas Majeed1, Matthew Magnuson1, Shella Keilholz1 1Georgia Institue of Technology / Emory University, Atlanta, Georgia, USA
2443.
Transportation of Mn2+ in the Brain of Rats with
Exclusive Caudoputaminal Lesions After
Fang Fang1, Li Wei1, Cheng Jiang2, Hao Lei1 1Wuhan Institute of Physics & Mathematics, Chinese Academy of Sciences, Wuhan, Hubei, People’s Republic of China; 2Wuhan University, Wuhan, Hubei, People’s Republic of China
2444.
High Dose of Mn2+ Injected Intracerebrally Causes
Neuronal Losses in the Ventral Tegmental
Yingxia Li1, Fang Fang1, Xuxia Wang1, Hao Lei1 1Wuhan Institute of Physics & Mathematics, Chinese Academy of Science, Wuhan, Hubei, People’s Republic of China
2445. Influence of Mn2+ Concentration on Transport Rates
Alison Thieme1, Lingyun Hu1, Cynthia Massaad1, Karen Smith1, Robia G. Pautler1 1Baylor College of Medicine, Houston, Texas, USA
2446. Tracing Olfactory Neural Circuits In Vivo Using 3D Manganese Enhanced MRI
Yoo Jeong Yim1, Hyun Jong Lee1, Hyung-Jin Kim1, Hun-Jong Dhong1, Seung Kyu Chung1, Keun-Ho Lim2, Ki-Soo Kim3, Jung Hee Lee1 1Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; 2Asan Institutes for Life Science, University of Ulsan, Seoul, Republic of Korea; 3Asan Medican Center, University of Ulsan, Seoul, Republic of Korea
2447. Mapping the Plasticity of the Striatonigral Pathway in a Transgenic Mice Model Using MEMRI
Ke Fang1, 2, Douglas Whyte1, Ilse Gantois1, Hong Wang1, Qizhu Wu1, Jasna Ribic1, Jyoti Lodhia1, John Drago1, Gary Egan1 1University of Melbourne, Melbourne, Australia; 2The Royal Children's Hospital, Melbourne, Australia
2448.
T1-Mapped Acute Cocaine-Induced Brain Activation with
Systemic Administrated
Xiping Liu1, Gaohong Wu2, Shi-Jiang Li2 1Medical College of Wisconsin, Milwaukee, Wisconsin, USA; 2Medical College of Wisconsin, Wisconsin, USA
2449. Does MEMRI Detect Apoptosis in the Rat Neonatal Hypoxic-Ischemic Stroke Model?
Marius Wideroe1, Christian Brekken1, Tina Bugge Pedersen1, Annemieke Kavelaars2, Jon Skranes1, Cobi Heijnen2, Ann-Mari Brubakk1 1Norwegian University of Science and Technology, Trondheim, Norway; 2University Medical Center Utrecht, Utrecht, Netherlands
2450. Characterization of the 6-OHDA Model of Parkinson’s Disease Using Manganese-Enhanced MRI
Maria Adele Rueger1, Jeeva P. Munasinghe1, Alan P. Koretsky1, Ronald D. McKay1 1NIH, Bethesda, Maryland, USA
2451. Fractionated Manganese-Enhanced MRI
Nicholas Adam Bock1, Julie B. Mackel1, Afonso C. Silva1 1National Institutes of Health, Bethesda, Maryland, USA
2452.
Manganese-Enhanced MRI Reveals Multiple Cellular and Vascular
Layers in Normal and
Govind Nair1, 2, Haiying Cheng2, Moon Kim2, Tsukasa Nagaoka2, Darin E. Olson2, Peter Thule2, Machelle T. Pardue2, Timothy Q. Duong2 1University of Massachusetts, Worcester, Massachusetts, USA; 2Emory University, Atlanta, Georgia, USA
2453. MEMRI Reveals Plasticity Changes in the Auditory Midbrains of Mice After Two-Tone Rearing
Xin Yu1, Dan H. Sanes2, Jing Zou3, Orlando Aristizábal1, Youssef Wadghiri Zaim1, Daniel H. Turnbull1 1New York University School of Medicine, New York, New York, USA; 2New York University, New York, New York, USA; 3University of Maryland College Park, College Park, Maryland, USA
2454. Laminar Specific MEMRI Enhancement of the Rat Spinal Cord In Vivo
Galit Pelled1, Stasia A. Anderson1, Michael J. Iadarola1, Alan P. Koretsky1 1National Institutes of Health, Bethesda, Maryland, USA
2455.
Manganese-Enhanced MRI Detects Distinct Patterns of Neuronal
Activation Following Anorexigenic
James R. Parkinson1, Owais Bashir Chaudhri1, Amy H. Herlihy2, Yu-Ting Kuo2, 3, Jimmy D. Bell2, Po-Wah So2, Waljit S. Dhillo1, Sarah A. Stanley1, Mohammad A. Ghatei1, Stephen R. Bloom1 1Imperial College London, Hammersmith Hospital, London, UK; 2MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, London, UK; 3School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
2456.
Determination of Laminar Specific Tracing of Somatosensory
Pathways Using Manganese
Jason Tucciarone1, Galit Pelled1, Kai Hsiang Chuang1, Alan P. Koretsky1 1National Institutes of Health, Bethesda, Maryland, USA
2457.
Functional Mapping of Rat Barrel Activation Following Whisker
Stimulation Using
Jun-Cheng Weng1, Jyh-Horng Chen1, Pai-Feng Yang1, Wen-Yih Isaac Tseng2 1National Taiwan University, Taipei, Taiwan; 2National Taiwan University College of Medicine, Taipei, Taiwan
2458. Manganese-Enhanced MRI of Axon Regeneration by Peptide Nanofiber Scaffold Induction
Kevin Chuen Wing Chan1, Yu Xiang Liang1, Edward Saikam Hui1, Phillis W. Kau1, Rutledge G. Ellis-Behnke1, 2, Gerald E. Schneider2, Kwok Fai So1, Ed Xue Kui Wu1 1The University of Hong Kong, Pokfulam, Hong Kong; 2Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
2459. Evaluation of Glaucomatous Optic Nerve Using In Vivo Manganese-Enhanced MRI
Kevin Chuen Wing Chan1, Sheryle Q. Fu1, Edward Sai Kam Hui1, Rachel S. Li1, Matthew Man Hin Cheung1, Darrell Ting Hung Li1, Kwok Fai So1, Ed Xue Kui Wu1 1The University of Hong Kong, Pokfulam, Hong Kong
2460. Monitoring Treatment Effects in Transgenic Mouse Model of Alzheimer’s Disease Using MRMI
Malgorzata Marjanska1, Thomas M. Wengenack2, Denise A. Reyes2, Geoffrey L. Curran2, Jan Grimm3, Joseph Lin1, Gregory M. Preboske2, Joseph F. Poduslo2, Michael Garwood1, Clifford R. Jack, Jr. 2 1Unviersity of Minnesota, Minneapolis, Minnesota, USA; 2Mayo Clinic College of Medicine, Rochester, Minnesota, USA; 3Rinat Neuroscience Corporation, South San Francisco, California, USA
2461.
Manganese-Enhanced MRI (MEMRI) and Diffusion-Weighted MRI
Mismatch in the Absence of a
David Bennett1, Nils Henninger2, 3, Marc Fisher2, 4, Chris Sotak1, 2 1Worcester Polytechnic Institute, Worcester, Massachusetts, USA; 2University of Massachusetts Medical School, Worcester, Massachusetts, USA; 3University of Massachusetts Memorial Healthcare, Worcester, Massachusetts, USA; 4University of Massachusetts Memorial Health Care, Worcester, Massachusetts, USA
2462. Preservation of Manganese Induced Contrast in Fixed Rat Brain
Kathrine Skak Madsen1, David Alberg Holm1, Lise Vejby Søgaard1, Ian John Rowland1 1Hvidovre Hospital, Copenhagen, Denmark
2463. In Vivo Assessment of Axonal Transport in Diabetic Mice Using Manganese-Enhanced MRI (MEMRI)
Faridis Serrano1, Tomoya Terashima, Lawrence C. B. Chan2, Robia G. Pautler1 1Baylor College of Medicine, Houston, Texas, USA; 2Baylor College of Medicine, Texas
2464. In Vivo Brain Connectivity: Optimization of Manganese Enhanced MRI for Neuronal Tract Tracing
Santiago Canals1, Michael Beyerlein1, Anna Lena Keller1, Yusuke Murayama1, Nikos K. Logothetis1 1Max Planck Institute for Biological Cybernetics, Tübingen, Germany
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