TRADITIONAL POSTERS

fMRI:  Technical

Hall 14.1                     Wednesday 13:30 - 15:30

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                  1924.    High Resolution SE-fMRI in Humans at 3 and 7 T Using a Motor Task

 

Andreas Schäfer1, Wietske van der Zwaag1, Susan Francis1, Penny A. Gowland1, Richard W. Bowtell1

1University of Nottingham, Nottingham, UK

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                  1925.    Comparitive Evaluation of a Multi-Echo fMRI Acquisition Technique Using Parallel Imaging

 

Heiko Schmiedeskamp1, 2, Rexford D. Newbould2, Roland Bammer2

1ETH Zurich, Zurich, Switzerland; 2Stanford University, Stanford, California, USA

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                  1926.    Functional Changes in CSF Volume Estimated Using Spectroscopic Water T2 Decay Measurement

 

Stefan K. Piechnik1, John Evans1, Lizet H.A. Bary1, 2, Richard G. Wise1, 3, Peter Jezzard1

1Oxford University, Oxford, UK; 2Technische Universiteit Eindhoven, Eindhoven, Netherlands; 3Cardiff University, Cardiff, UK

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                  1927.    High-Resolution Human Functional MRI: Feasibility and Specificity at High (3T) and Ultra-High

                              (7T) Fields

 

Itamar Kahn1, 2, Chris J. Wiggins2, Graham Wiggins2, Karla L. Miller3, Thomas Benner2, Bruce Fischl2, 4, Lawrence L. Wald2, Bradford L. Dickerson2, Randy L. Buckner1, 2

1Harvard University, Cambridge, Massachusetts, USA; 2MGH, Charlestown, Massachusetts, USA; 3Oxford, Oxford, UK; 4MIT, Charlestown, Massachusetts, USA

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                  1928.    Finger-Tapping Modulates Functional Synchrony in the Motor Cortex Network

 

Yin Xu1, Gaohong Wu1, Shi-Jiang Li1

1Medical College of Wisconsin, Milwaukee, Wisconsin, USA

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                  1929.    Using Independent Component Analysis to Measure Language Laterality

 

Anthony B. Waites1, Emil Johansson, 12, David F. Abbott1, Graeme D. Jackson1

1Brain Research Institute, Heidelberg West, Vic, Australia; 2University of Lund, Lund, Sweden

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                  1930.    Mapping of Task-Relevant Activation in Human Posterior Parietal Cortex for Processing Spatial and

                               Non-Spatial Stimulus Characteristics

 

Dorothe A. Poggel1, 2, Dae-Shik Kim1, Joseph F. Rizzo2, 3, Louis J. Toth1

1Boston University Medical School, Boston, Massachusetts, USA; 2Boston VA Medical Center, Boston, Massachusetts, USA; 3Harvard Medical School, Boston, Massachusetts, USA

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                  1931.    Interclass Correlation Coefficient as a Measure of Drug Intervention in FMRI

 

Alejandro Caceres1, Daeana L. Hall1, Fernando O. Zelaya1, Steven C.R. Williams1, Mitul A. Mehta1

1Institute of Psychiatry, London, UK

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                  1932.    Probing Into Specificity of Neuronal Circuits Through fMRI Refractory Response

 

Yulwan Sung1, Masayuki Kamba1, Seiji Ogawa1

1Hamano Life Science Research Foundation, Tokyo, Japan

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                  1933.    Comparison of Unilateral and Bilateral Complex Finger Tapping-Related Activation in the

                              Precentral Gyrus

 

Micheal D. Phillips1, Craig Israel Horenstein1, Mark J. Lowe1

1Cleveland Clinic, Cleveland, Ohio, USA

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                  1934.    Comparison of GE and SE BOLD fMRI Techniques in Temporal-Encoding Iso-Orientation Maps.

 

ChanHong Moon1, Hiro Fukuda1, Ping Wang1, Seong-Gi Kim1

1University of Pittsburgh, Pittsburgh, Pennsylvania, USA

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                  1935.    Investigating fMRI and fNIRS Signal with Balloon Model During Breath Hold Task

 

Uzay Emrah Emir1, Cengizhan Ozturk1, Ata Akin1

1Bogazici University, Istanbul, Turkey

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                  1936.    BOLD Contrast-To-Noise Ratio Across Field Strengths Under Global Stimulus

 

Christina Triantafyllou1, 2, Lawrence L. Wald2, Richard D. Hoge3

1MIT, Cambridge, Massachusetts, USA; 2MGH, Charlestown, Massachusetts, USA; 3Unite de Neuroimagerie fonctionelle, Montreal, QC, Canada

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                  1937.    Evidence of the BOLD Post-Undershoot Rebound

 

Kevin Murphy1, Jerzy Bodurka1, Peter Anthony Bandettini1

1National Institute of Mental Health, Bethesda, Maryland, USA

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                  1938.    Quantitative Comparison of Two Biophysical Models for the BOLD fMRI Signal: A Theoretical Study

 

Chenguang Zhao1, Hanzhang Lu1

1University of Texas Southwestern Medical Center, Dallas, Texas, USA

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                  1939.    Inferring Evoked and Baseline Cerebral Blood Flow, Volume, and Oxygen Metabolism from Dynamic

                               BOLD and ASL Measurements

 

Theodore J. Huppert1, Monica S. Allen2, David A. Boas1

1Massachusetts General Hospital, Charlestown, Massachusetts, USA; 2University of Texas at Arlington, Arlington, Texas, USA

 

 

fMRI:  Pulse Sequences

Hall 14.1                     Wednesday 13:30 - 15:30

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                  1940.    A Time Efficient High Resolution Multi-Echo FLASH Sequence

 

Patrick Michael Heiler1, Sebastian Schmitter1, Lothar Rudi Schad1

1German Cancer Research Center, Heidelberg, Germany

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                  1941.    Triple Spiral with Asymmetric Spin Echo: A New Method for Improved BOLD fMRI in Regions of

                              Magnetic Susceptibility  Induced Field Inhomogeneity

 

Kimberly D. Brewer1, 2, James A. Rioux2, Ryan C.N. D'Arcy, 12, Chris V. Bowen, 12, Steven D. Beyea, 12

1Dalhousie University, Halifax, Nova Scotia, Canada; 2National Research Council of Canada, Halifax, Nova Scotia, Canada

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                  1942.    Single-Shot Z-Shimmed Sensitivity-Encoded Spiral-In/Out Imaging for fMRI

 

Trong-Kha Truong1, Allen W. Song1

1Duke University, Durham, North Carolina, USA

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                  1943.    Reduction of Magnetic Susceptibility Artifacts in Olfactory fMRI with SENSE-GESEPI-EPI Method

 

Qing X. Yang1, Erin K. Zimmerman1, Jianli Wang1, Paul J. Eslinger1, Robert Grunfeld1, Jeffery Vesek1, Mark D. Meadowcroft1, James R. Connor1, Michael B. Smith2

1Penn State University College of Medicine, Hershey, Pennsylvania, USA; 2Novartis Institutes for BioMedical Research, Inc., Cambridge, Massachusetts, USA

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                  1944.    Automatic Slice-Dependent Frequency Adjustments for SSFP fMRI

 

Ming-Long Wu1, 2, Teng-Yi Huang3, Pei-Hsin Wu1, Yi-Yu Shih1, Ming-Chung Chou1, 4, Hua-Shan Liu1, 4, Hsiao-Wen Chung1, 4, Cheng-Yu Chen4

1National Taiwan University, Taipei, Taiwan; 2Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; 3National Taiwan University of Science and Technology, Taipei, Taiwan; 4Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan

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                  1945.    Increasing the Sensitivity to BOLD Contrast in High Resolution fMRI Studies by Using 3D

                              Spiral Technique

 

Yanle Hu1, Gary H. Glover1

1Stanford University, Stanford, California, USA

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                  1946.    3D kSPA for High Spatial and High Temporal Resolution fMRI

 

Chunlei Liu1, Yanle Hu1, Jingjing Lu2, Gary H. Glover1, Michael E. Moseley1

1Stanford University, Stanford, California, USA; 2Peking Union Medical College Hospital, Beijing, People’s Republic of China

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                  1947.    Functional Neuroimaging of Inner Field-Of-Views Using FLASH with 2D-Selective RF Excitations

 

Wolfgang Weber-Fahr1, 2, Jürgen Finsterbusch1, 2

1University Medical Center Hamburg-Eppendorf, Hamburg, Germany; 2Neuroimage Nord, Hamburg-Kiel-Lübeck, Germany

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                  1948.    Localized Parallel Echo Volume Imaging at 1.5 T: A First Extensive fMRI Study

 

Cécile Rabrait1, Philippe Ciuciu1, Alejandro Ribés1, Cyril Poupon1, Patrick Le Roux2, Denis Le Bihan1, Franck Lethimonnier1

1CEA, Orsay, France; 2General Electric, Buc, France

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                  1949.    SSFP fMRI with Parallel Interleaved Multiple Frequency Acquisition

 

Pei-Hsin Wu1, Ming-Long Wu, Teng-Yi Huang2, Ming-Chung Chou, Hua-Shan Liu, Cheng-Yu Chen3, Hsiao-Wen Chung

1National Taiwan University, Taipei, Taiwan, Taiwan; 2National Taiwan University of Science and Technology; 3Tri-Service General Hospital,

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                  1950.    SSFP fMRI at 0.37 Mm3 Voxel Volume: Effects of Spatial Resolution on SNR and Functional Sensitivity

 

Ming-Long Wu1, 2, Pei-Hsin Wu1, Teng-Yi Huang3, Yi-Yu Shih1, Ming-Chung Chou1, 4, Hua-Shan Liu1, 4, Hsiao-Wen Chung1, 4, Cheng-Yu Chen4

1National Taiwan University, Taipei, Taiwan; 2Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; 3National Taiwan University of Science and Technology, Taipei, Taiwan; 4Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan

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                  1951.    A New Method of Motion-Compensated Spinal fMRI: Identifying Human Spinal Cord Function with

                               Increased Sensitivity and Reproducibility

 

Chase R. Figley1, Patrick W. Stroman1

1Queen's University, Kingston, Ontario, Canada

 

 

fMRI:  Methods

Hall 14.1                     Wednesday 13:30 - 15:30

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                  1952.    Quantitative Analysis of Brain Functional Hemodynamics with Time-Series T1 Mapping

 

Jung-Jiin Hsu1, Gary H. Glover1

1Stanford University, Stanford, California, USA

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                  1953.    T2 Weighted fMRI with Whole Brain Coverage at Ultra-High Fields

 

Johannes Ritter1, Eddie Auerbach1, Gregor Adriany1, Kamil Ugurbil1

1University of Minnesota, Minneapolis, Minnesota, USA

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                  1954.    Quantitative Relationships of Metabolic and Vascular Parameters in Brain Activation:

                              A Multi-Modal fMRI Study

 

Hanzhang Lu1, Chenguang Zhao1, Kelly Lewis-Amezcua1

1University of Texas Southwestern Medical Center, Dallas, Texas, USA

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                  1955.    Dynamic Measurement of Functional Changes in Venous Cerebral Blood Volume at 3 T

 

Jean Jing Chen1, Gilbert Bruce Pike1

1Montreal Neurological Institute, Montreal, Quebec, Canada

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                  1956.    Quality of Single-Trial Discrimination in Simulataneous EEG/fMRI

 

Robin I. Goldman1, Adam D. Gerson2, Marios G. Philiastides2, David Friedman3, Truman R. Brown1, Paul Sajda2

1Columbia University, New York, New York, USA; 2Columbia University, New York, USA; 3New York State Psychiatric Institute, New York, New York, USA

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                  1957.    Acquisition Strategies to Improve the Specificity of Block-Design fMRI Studies of Overt Speech

 

David A. Soltysik1, James S. Hyde1

1Medical College of Wisconsin, Milwaukee, Wisconsin, USA

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                  1958.    Encoding of EEG in MR Images

 

Lars G. Hanson1, Arnold Skimminge1, Christian G. Hanson1

1Copenhagen University Hospital, Hvidovre, Denmark

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                  1959.    Optimized fMRI Protocol for Fear Conditioning Experiments at 3 Tesla Using Parallel

                              Acquisition Technique

 

Alexander Kroll1, 2, Julia Ofer1, Christiane Hermann1, Herta Flor1, Lothar Rudi Schad2

1University of Heidelberg, Central Institute of Mental Health, Mannheim, Germany; 2German Cancer Research Center, Heidelberg, Germany

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                  1960.    Monitoring of the Consistency of Brain Activation by Using a Dynamic Analysis of T-Statistics -

                              An Application to Conventional Mapping of the Motor Areas

 

Toshiharu Nakai1, Epifanio Bagarinao2, Kenichi Ohishi3, Chikako Kato4, Kayako Matsuo1

1National Center for Geriatrics and Gerontology, Ohbu, Aichi, Japan; 2National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaragi, Japan; 3Johns Hopkins School of Medicine, Baltimore, Maryland, USA; 4Toyohashi Sozo College, Toyohashi, Aichi

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                  1961.    Functional Magnetic Resonance Imaging (fMRI)-A Useful Tool for the Assessment of

                              Hypothalamus Function?

 

Abdelmalek Benattayallah1, Daniel Flanagan2, Binu Krishnan2, Claire Ball3, Jonathan Fulford3, Kenneth Macleod3, Ian R. Summers1, Angela Shore3

1University of Exeter, Exeter, UK; 2Peninsula Medical School, Plymouth, UK; 3Peninsula Medical School, Exeter, UK

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                  1962.    Modelling BOLD Response in Auditory Cortex with Baloon Hemodynamic Model

 

Piotr Bogorodzki1, Tomasz Wolak1, Ewa Piatkowska-Janko1, Mateusz Orzechowski1, Robert Kuriata1, Henryk Skarzynski2, Wojciech Gradkowski3

1Warsaw University of Technology, Warsaw, Poland; 2Institute of Physiology and Pathology  of Hearing, Warsaw, Poland; 3Warsaw University of Technology, Poland

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                  1963.    Effects of Capillary Orientation on Muscle T2/T2*: Comparison of Numerical Simulations with

                              Empirical Data

 

Otto Alexander Sanchez1, Anneriet Marie Heemskerk1, Bruce Murray Damon1

1Vanderbilt University, Nashville, Tennessee, USA

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                  1964.    Clustering fMRI Data Using a Spatiotemporal Geodesic K-Means Algorithm

 

Richard Andrew James Masterton1, 2, David F. Abbott1, 2, Graeme D. Jackson1, 2

1Brain Research Institute, Melbourne, Victoria, Australia; 2The University of Melbourne, Melbourne, Victoria, Australia

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                  1965.    An MR-Compatible Haptic Device for fMRI Investigations of Force Control

 

Markus Klarhöfer1, Sven Haller2, Dominique Chapuis3, Roger Gassert4, Aidan Roche4, Klaus Scheffler1, Etienne Burdet4

1University of Basel, Basel, Switzerland; 2University Hospital Basel, Basel, Switzerland; 3Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland; 4Imperial College London, London, UK

 

 

fMRI:  Non-BOLD Contrasts

Hall 14.1                     Wednesday 13:30 - 15:30

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                  1966.    Functional Magnetic Resonance Imaging of Cortical Tissue Slices by Means of Signal Enhancement by

                              Extravascular Water Protons (SEEP) Contrast

 

Patrick W. Stroman1, David Andrew1

1Queen's University, Kingston, Ontario, Canada

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                  1967.    Functional MRI of the Brainstem and Cervical Spinal Cord of Children Based on SEEP Contrast

 

Patrick W. Stroman1, Jane Lawrence2, Jennifer Kornelsen2

1Queen's University, Kingston, Ontario, Canada; 2Stanford University, Palo Alto, California, USA

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                  1968.    Functional Contrast Based on iDQC - Influence of the Correlation Distance

 

Andreas Schäfer1, 2, Harald E. Möller2

1University of Nottingham, Nottingham, UK; 2Max Planck Institute for Human Cognitive and Brain Science, Leipzig, Germany

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                  1969.    Hypercapnia-Induced Vasoreactivity as Evaluated by Vascular-Space-Occupancy (VASO)

                              Dependent fMRI

 

Hanzhang Lu1, Uma Yezhuvath1, Kelly Lewis-Amezcua1, Jinsoo Uh1, Feng Xu1, Rani Varghese1

1University of Texas Southwestern Medical Center, Dallas, Texas, USA

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                  1970.    Direct Comparison of Multi-Echo BOLD and VASO Based fMRI

 

Erik Groenewold1, Hans Hoogduin2

1University Medical Center Groningen, University of Groningen; 2University Medical Center Groningen, University of Groningen, Groningen, Netherlands

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                  1971.    Single-Shot ADC Imaging for fMRI

 

Allen W. Song1, Hua Guo1, Trong-Kha Truong1

1Duke University, Durham, North Carolina, USA

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                  1972.    Direct Detection of Neuronal Magnetic Field Changes Using MRI:Timing Effect of Stimulation

 

Yiqun Xue1, Xiying Chen1, Thomas Grabowski1, Jinhu Xiong1

1University of Iowa, Iowa city, Iowa, USA

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                  1973.    Improved Temporal Resolution in Time-Series ASL Perfusion Imaging with Single-Shot

                              3D GRASE Using Variable Shared Control Phases

 

David A. Feinberg1, 2, Sudhir Ramanna1

1Advanced MRI Technologies and Redwood Regional Medical Group, Sebastopol, California, USA; 2CIND, VA Medical Center, San Francisco, California, USA

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                  1974.    Lorentz Effect Imaging of Ionic Currents in Solution

 

Trong-Kha Truong1, Alexandru Avram1, Allen W. Song1

1Duke University, Durham, North Carolina, USA

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                  1975.    Functional 31P-{1H} EPSI with 6 S Temporal Resolution of the Human Brain

 

Marco Ulrich1, Tim Wokrina1, Nuran Tunc-Skarka1, Peter Bachert2, Gabriele Ende1

1Central Institute of Mental Health, Mannheim, Germany; 2German Cancer Research Center, Heidelberg, Germany

 

 

fMRI:  Resting State

Hall 14.1                     Wednesday 13:30 - 15:30

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                  1976.    EPI Magnitude Signal Formation in the Proximity of Straight Conductor Subjected to a

                             Weak Electric Current.

 

Jerzy Bodurka1, Peter Bandettini1

1National Institute of Mental Health, NIH, Bethesda, Maryland, USA

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                  1977.    Reducing Correlated Noise in fMRI Data

 

Jacco A. de Zwart1, Peter van Gelderen1, Masaki Fukunaga1, Jeff H. Duyn1

1National Institutes of Health, Bethesda, Maryland, USA

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                  1978.    Reducing Effects of Drift in fMRI Data Using Joint Reconstruction of R2* and Field Maps

 

Valur Olafsson1, Magnus Ulfarsson1, Jeffrey A. Fessler1, Douglas C. Noll1

1University of Michigan, Ann Arbor, Michigan, USA

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                  1979.    Determination of Inversely Correlated Resting State Brain Functional Networks Using Cluster Analysis

 

Cheuk Ying Tang1, Eric Leung1, David Carpenter1, Johnny Ng1

1Mount Sinai School of Medicine, New York, New York, USA

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                  1980.    Resting-State Functional Connectivity and Stimulation-Induced Neural Activity in the Cortex

                              and Sub-Cortical Structures of Rat Brain

 

Fuqiang Zhao1, Tiejun Zhao1, Lei Zhou1, Qiulin Wu1, Zhi Yang1, Xiaoping Hu1

1Emory / Georgia Tech, Atlanta, Georgia, USA

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                  1981.    Extracting the Resting-State BOLD Signal from an Event-Related fMRI Study

 

Minjie Wu1, Robert Tamburo1, Greg Siegle1, Howard J. Aizenstein1

1University of Pittsburgh, Pittsburgh, Pennsylvania, USA

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                  1982.    MR Signal Fluctuations and Regional Vasomotion

 

Homer Pien1, Wei-Ting Zhang1, Emmanuelle DiTomaso1, D. G. Duda2, Rakesh Jain1, Tracy Batchelor1, A. Gregory Sorensen1

1Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA; 2Massachusetts General Hospital and Harvard Medical School, Bosotn, Massachusetts, USA

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                  1983.    Mitigation of Physiological Noise in the fMRI Time-Series by CSF Nulling

 

Christina Triantafyllou1, 2, Lawrence L. Wald2

1MIT, Cambridge, Massachusetts, USA; 2MGH, Charlestown, Massachusetts, USA

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                  1984.    Characterization of an Intrinsic Low-Frequency Component at Around 0.025 Hz in Steady-State

                              fMRI Signals

 

Yin Xu1, Guofan Xu1, Gaohong Wu1, Shi-Jiang Li1

1Medical College of Wisconsin, Milwaukee, Wisconsin, USA

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                  1985.    Connectivity Analysis During Motor Imagery and Motor Execution Using DCM

 

Christian H. Kasess1, Ross Cunnington2, Rupert Lanzenberger1, Ewald Moser1, Lukas Pezawas1, Christian Windischberger1

1Medical University of Vienna, Vienna, Austria; 2University of Melbourne, Melbourne, Australia

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                  1986.    Low-Frequency Fluctuations in the Cardiac Rate Contribute to Variance in the Resting-State

                              fMRI BOLD Signal

 

Karin Shmueli1, Peter van Gelderen1, Jacco A. de Zwart1, Silvina G. Horovitz1, Masaki Fukunaga1, J Martijn Jansma1, Jeff H. Duyn1

1National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA

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                  1987.    Group Independent Component Analysis Reveals Consistent Resting-State Networks Across

                             Multiple Sessions

 

Sharon Chen1, Yihong Yang1, Wang Zhan1, Elliot A. Stein1, Carol S. Myers1, Stephen J. Heishman1, Keh-Shih Chuang2, Thomas J. Ross1

1National Institute on Drug Abuse, Baltimore, Maryland, USA; 2National Tsing-Hua University, Hsin Chu, Taiwan

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                  1988.    Structural Equation Modeling of Resting-State Temporal Lobe Functional Connectivity

 

George Andrew James1, Stephen M. LaConte1, Richard Cameron Craddock1, Thomas Reid Henry2, Helen S. Mayberg2, Xiaoping P. Hu1

1Emory University and Georgia Institute of Technology, Atlanta, Georgia, USA; 2Emory University, Atlanta, Georgia, USA

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                  1989.    Functional Hierarchy of the Visual System as Revealed by Resting-State Connectivity

 

Egbert Jan Willem Bleeker1, Hubert M.J. Fonteijn2, Elena Shumskaya2, Jens Schwarzbach3, David G. Norris2

1Leiden University Medical Center, Leiden, Netherlands; 2F.C. Donders Centre for Cognitive Neuroimaging, Nijmegen, Netherlands; 3University of Trento, Trento, Italy

 

 

fMRI:  Miscellaneous Neuro Applications

Hall 14.1                     Wednesday 13:30 - 15:30

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                  1990.    Cortical Activation in Reduced During Motor Imagery in Amyotrophic Lateral Sclerosis

 

Biba Rhiannon Stanton1, Victoria C. Williams1, Peter Nigel Leigh1, Steven Williams1, Andrew Simmons1

1Institute of Psychiatry, King's College London, London, UK

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                  1991.    Hypothalamic Functional MRI Response After Glucose Ingestion Is Diminished in Patients with

                              Type 2 Diabetes Mellitus

 

Paul Smeets1, Solrun Vidarsdottir2, Matthias van Osch2, Max Viergever1, Diana Eichelsheim2, Johannes Romijn2, Hanno Pijl2, Jeroen van der Grond2

1University Medical Center Utrecht, Utrecht, Netherlands; 2Leiden University Medical Center, Netherlands

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                  1992.    Brain fMRI Correlates of Pain in Diabetes

 

Iain D. Wilkinson1, Rajiv A. Gandhi2, Dinesh Selvarajah2, Michael D. Hunter1, Celia J. Emery2, Paul D. Griffiths1, Solomon Tesfaye2

1University of Sheffield, Sheffield, UK; 2Royal Hallamshire Hospital, Sheffield, UK

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                  1993.    A Network Analysis of Acupuncture Effects by Functional Connectivity MRI

 

Lin Yang1, Wei Qin2, Xiulai Gao1, Jie Tian2, Peng Chen3, Jianping Dai4, Hongyan Chen4

1Department of Anatomy and Embryology,China Capital Medical University, Beijing, People’s Republic of China; 2Medical Image Processing Group, Institute of Automation, Chinese Academy of Sciences, Beijing, People’s Republic of China; 3Beijing University of Chinese Medicine, Beijing, People’s Republic of China; 4Department of Radiology, Beijing Tiantan Hospital£Capital University of Medical Sciences, Beijing, People’s Republic of China

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                  1994.    Brain Activation in Overactive Bladder Patients Evaluated by Pharmacological fMRI

 

Shweta Moonat1, Michael Pontari1, Steve Lebovitch1, Brett Lebed1, Michael Ruggieri1, Scott H. Faro1, Feroze B. Mohamed1

1Temple University, Philadelphia, Pennsylvania, USA

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                  1995.    BOLD fMRI Response in the Motor Cortex Is Strongly Linked with CO2 Reactivity in Patients

                              with Carotid Artery Disease.

 

Stephen David Goode1, Christine Ojango1, Dorothee Auer1

1Queens Medical Centre, Nottingham, UK

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                  1996.    Characterization of Cortical Activation Patterns in Action Induced Focal Dystonia by 3.0 T fMRI

 

Karl Titus Hoffmann1, Tina Islam1, Harald Bruhn1, Sein Schmidt2, Lutz Lüdemann1, Thomas Trottenberg2, Andreas Kupsch2

1Charité Virchow, Berlin, Germany; 2Charité,

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                  1997.    fMRI of Brain Activity During Active Place Avoidance in a Task of Divided Attention

 

Martin Meier1, 2, Peter Ehrhard2, Andre A. Fenton3, Kamil Vlcek3, Barbara Wolynski1, Dieter Leibfritz2

1University of Magdeburg, Magdeburg, Germany; 2University of Bremen, Bremen, Germany; 3Academy of Science of the Czech Republic, Prague

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                  1998.    Analyzing Structural and Functional Imaging Data on the Cortical Surface

 

Donald G. McLaren1, Adrian A. Epstein2, Josh S. Shimony2, Harold Burton2, David C. Van Essen2, Andy L. Alexander1, Sterling C. Johnson1

1University of Wisconsin, Madison, Wisconsin, USA; 2Washington University School of Medicine, St. Louis, Missouri, USA

 

 

fMRI:  Animal Models

Hall 14.1                     Wednesday 13:30 - 15:30

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                  1999.    Networks of Correlated Activity in the phMRI Response to Amphetamine Resolved by Cluster Analysis

 

Adam James Schwarz1, Alessandro Gozzi1, Torsten Reese1, Angelo Bifone1

1GlaxoSmithKline / Psychiatry CEDD, Verona, Veneto, Italy

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                  2000.    Neural Substrates of the Orexigenic Hormone Ghrelin: A Pharmacological MRI Study in the Rat

 

Alessandro Gozzi1, Adam Schwarz1, Valerio Crestan1, Carla Di Francesco1, Francesca Marini1, Mario Massagrande1, Torsten Reese1, Phil Gerrard1, Christian Heidbreder1, Sergio Melotto1, Angelo Bifone1

1Centre of Excellence for Drug Discovery, Psychiatry, GlaxoSmithKline Medicines Research Centre, Verona, Italy

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                  2001.    Drug-Anaesthetic Interaction in Pharmacological MRI: The Case of the Psychotogenic

                              Agent Phencyclidine

 

Alessandro Gozzi1, Adam Schwarz1, Torsten Reese1, Valerio Crestan1, Angelo Bifone1

1Centre of Excellence for Drug Discovery, Psychiatry, GlaxoSmithKline Medicines Research Centre, Verona, Italy

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                  2002.    Assessment of Ocular Dominance Plasticity with Functional MRI at 3 Tesla

 

Jeffrey Keating Thompson1, Louis J. Toth1, Itamar Ronen1, Dae-Shik Kim1

1Boston University School of Medicine, Boston, Massachusetts, USA

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                  2003.    Coupling Between Simultaneously Recorded BOLD Response and Neuronal Activity in the

                              Rat Somatosensory Cortex  Under Different Anesthetics

 

Joanna K. Huttunen1, Olli Gröhn1, Markku Penttonen1, 2

1University of Kuopio, Kuopio, Finland; 2University of Jyväskylä, Jyväskylä, Finland

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                  2004.    Amphetamine PharmacoMRI in the Rat Under Isoflurane Anesthesia

 

Carmen de Groote1, Shane McKie1, Bill Deakin1, Steve Ross Williams1

1University of Manchester, Manchester, Greater Manchester, UK

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                  2005.    Characterizing the Differential Effects of Selective Cannabinoid Agonists on Brain Activity in

                              Awake Rats Using Pharmacological MRI

 

Chih-Liang Chin1, Terese R. Seifert1, Ann E. Tovcimak1, Vincent P. Hradil1, Michael J. Dart1, Gin C. Hsieh1, Michael D. Meyer1, Betty B. Yao1, Bryan F. Cox1, Gerard b. Fox1

1Abbott Laboratories, Abbott Park, Illinois, USA

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                  2006.    Activity Mappings in Olfactory Bulb of Newborn Rabbits Elicited by Odor Stimulation Using Quantitative

                               Manganese Enhanced MRI

 

Jean-marie Bonny1, Gilles Sicard2, Yves Maurin3, Cécile Keller1, Benoist Schaal2, Olivier Rampin3, Jean-Pierre Renou1, André Holley2, Philippe Andrey3, Gérard Coureaud2

1INRA, Saint-Genès Champanelle, France; 2CNRS, Dijon, France; 3INRA, Jouy en josas, France

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                  2007.    Selective Modulation of Functional Connectivity in the Brain’s Reward Pathway by D3

                              Receptor Antagonism

 

Adam James Schwarz1, Alessandro Gozzi1, Torsten Reese1, Christian A. Heidbreder1, Angelo Bifone1

1GlaxoSmithKline / Psychiatry CEDD, Verona, Veneto, Italy

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                  2008.    Modeling Dopamine Dynamics Using Combined Microdialysis and MRI Measurements.

 

Bruce G. Jenkins1, Ji-Kyung Choi1, Andac Hamamci1, Joseph B. Mandeville1, Bruce R. Rosen1, Yin-Ching Iris Chen1

1Massachusetts General Hospital, Charlestown, Massachusetts, USA

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                  2009.    Investigating the Influence of Anesthesia on Resting State Connectivity in Rats Using Multiple

                              Analysis Techniques

 

Kathleen A. Williams1, Stephen M. LaConte1, Scott J. Peltier2, Shella D. Keilholz1

1Georgia Institute of Technology/Emory University, Atlanta, Georgia, USA; 2University of Michigan, Ann Arbor, Michigan, USA

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                  2010.    Rat BOLD fMRI Using Domitor for Anesthesia: Investigation of Stimulus Dependence and Negative

                              BOLD Response in Somatosensory Network

 

Fuqiang Zhao1, Tiejun Zhao1, Lei Zhou1, Qiulin Wu1, Xiaoping Hu1

1Emory / Georgia Tech, Atlanta, Georgia, USA

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                  2011.    In Vivo Mapping of Functional Connectivity in Active Neurotransmitter Systems Using

                              Pharmacological MRI

 

Adam James Schwarz1, Alessandro Gozzi1, Torsten Reese1, Angelo Bifone1

1GlaxoSmithKline / Psychiatry CEDD, Verona, Veneto, Italy

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                  2012.    Quantification of Resting State CMRO2 Using Low-Frequency Hemodynamic Oscillations in Rat Brains

 

Young R. Kim1, Bharat B. Biswal2, Bruce R. Rosen1

1Athinoula Martinos Center for Biomedical Imaging/Massachusetts General Hospital, Charlestown, Massachusetts, USA; 2UMDNJ-New Jersey Medical School/ Department of Radiology, Newark, New Jersey, USA

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                  2013.    Towards Functional MRI in Blood Free Rats

 

Helen E. D'Arceuil1, Richard M. Kiral2, Alex J. de Crespigny1

1Massachusetts General Hospital, Charlestown, Massachusetts, USA; 2Synthetic Blood International Inc., Costa Mesa, California, USA

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                  2014.    Analysis of Amphetamine-Induced BOLD fMRI Signals in Striatum Indicate Novel Temporal

                              Regulation by Insulin

 

Jason M. Williams1, John C. Gore1, Malcolm J. Avison1, Aurelio Galli1

1Vanderbilt University Medical Center, Nashville, Tennessee, USA

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                  2015.    Spin-Echo fMRI of the Temporal Lobe in Awake, Behaving Monkeys at 7T

 

Jozien B.M. Goense1, Shih-Pi Ku1, Hellmut Merkle2, Andreas S. Tolias1, 3, Nikos K. Logothetis1

1Max-Planck Institute for Biological Cybernetics, Tübingen, Germany; 2NIH/NINDS, Bethesda, Maryland, USA; 3Baylor College of Medicine, Houston, Texas, USA

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                  2016.    Functional MRI of Spontaneous Absence Seizures in a Genetic Rat Model

 

Olivier David1, Isabelle Guillemain2, Sébastien Reyt3, Colin Deransart2, Christoph Segebarth3, Antoine Depaulis2

1UM UJF-Inserm 594, Grenoble, France; 2UM UJF-Inserm 704, France; 3UM UJF-Inserm 594, France

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                  2017.    Functional MRI in a Zebra Finch Model of Dysfluency Shows Altered BOLD Responses to

                              Familiar Birdsong Stimuli

 

Henning U. Voss1, Delanthi Salgado-Commissariat2, Douglas Ballon1, Santosh A. Helekar2

1Cornell Medical College, New York, New York, USA; 2The Methodist Neurological Institute, Houston, Texas, USA

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                  2018.    Do Differences in BOLD and CBV Responses to Cortical Stimulation During mGluR5 Blockade Reflect

                               Regional Differences in Neurovascular Coupling Mechanisms?

 

Hazel Sloan1, Vivienne Austin1, Andrew Lowe1, Michael O'Neill2, Paul Matthews3, Nicola Sibson1

1University of Oxford, Oxford, UK; 2Eli Lilly & Co. Ltd, UK; 3GlaxoSmithKline, UK

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                  2019.    Dynamic Response of the Livers of Chronic Ethanol-Treated Rats to Oxygenation Changes:

                              An fMRI Study

 

Manfred Brauer1, Melissa J. Yau2, Lesley M. Foley3

1University of Guelph, Guelph, Ontario, Canada; 2University of Guelph, Guelph, Canada; 3Carnegie Mellon University, Pittsburgh, Pennsylvania, USA

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                  2020.    Role of Glutamate Release in Ketamine-Induced Blood-Oxygenation Level Dependent

                              (BOLD) Responses: An fMRI Study in Rats.

 

Carmen de Groote1, Shane McKie1, Bill Deakin1, Steve Ross Williams1

1University of Manchester, Manchester, UK

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                  2021.    Functional Brain Mapping During Acute Stimulation Through Chronic Electrode Implants in Rat

 

Jeff F. Dunn1, Ursula I. Tuor, 12, Jonn Kmech1, Nicole A. Young1, G Campbell Teskey1, Pamela A. Valentine1

1University of Calgary, Calgary, AB, Canada; 2National Research Council, Calgary, AB, Canada

 

 

fMRI Applications:  Neuroscience

Hall 14.1                     Wednesday 13:30 - 14:30

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                  2022.    The Neural Correlates of Interpreting Speech-In-Noise in Children with Unilateral Sensorineural Hearing

                               Loss Investigated Using a Functional MRI Paradigm with Silent Gradient Intervals

 

Vincent J. Schmithorst1, Robert W. Keith2, David Brown1, Scott K. Holland1

1Children's Hospital Medical Center, Cincinnati, Ohio, USA; 2University of Cincinnati, Cincinnati, Ohio, USA

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                  2023.    Congruence Between BOLD Activation Pattern and the Maximal Suppression Effect by TMS During a

                               Simple Visual Discrimination Task

 

Axel Thielscher1, Alexandra Reichenbach1, Kamil Ugurbil1, 2, Kamil Uludag1

1MPI for biological Cybernetics, Tübingen, BW, Germany; 2University of Minnesota, Minneapolis, Minnesota, USA

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                  2024.    Multisensory Recruitment Associated with REM Sleep Eye Movements: An fMRI Study

 

Charles Chong-Hwa Hong1, James C. Harris2, Godfrey D. Pearlson3, 4, Jin-Suh Kim5, Vince D. Calhoun6, 7, James H. Fallon8, Xavier Golay9, Joseph S. Gillen, 210, Peter C.M. van Zijl, 210, David S. Zee2, James J. Pekar, 210

1Johns Hopkins University, Baltimore, Maryland; 2Johns Hopkins University, Baltimore, Maryland, USA; 3Yale University, New Haven, Connecticut, USA; 4Hartford Hospital, Hartford, Connecticut, USA; 5University of Iowa, Iowa City, Iowa, USA; 6University of New Mexico, Albuquerque, New Mexico; 7The MIND Institute, Albuquerque, New Mexico, USA; 8University of California, Irvine, Irvine, California, USA; 9Singapore Bioimaging Consortium, Singapore, Singapore; 10Kennedy Krieger Institute, Baltimore, Maryland, USA

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                  2025.    Relating Yourself to Visual Scenes Incongruous with Body Posture: An fMRI Study

 

Kayako Matsuo1, Epifanio Tila Bagarinao, Jr. 2, Chikako Kato3, Toshiharu Nakai1

1National Center for Geriatrics and Gerontology, Obu, Aichi, Japan; 2National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan; 3Toyohashi Sozo University, Toyohashi, Aichi, Japan

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                  2026.    Comparing Functional Connectivity in Default Mode of Brain Between Adult and Children During

                              Mental Calculation

 

Feiyan Chen1, Lixia Tian2, Hongjian He1, Weimin Zhang1, Zhikang Wang1, Tianzi Jiang2

1Zhejiang University, Hangzhou, Zhejiang, People’s Republic of China; 2Institute of Automation, Chinese Academy of Sciences, Beijing, People’s Republic of China

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                  2027.    Neural Correlates of Attentional Control of Conflict Processing: fMRI Evidence from a Stroop

                              Match-To-Sample Task

 

Tilman Schulte1, Eva Maria Muller-Oehring2, Dirk Mayer3, Shara Vinco1, Adolf Pfefferbaum1, Edith V. Sullivan2

1SRI International, Menlo Park, California, USA; 2Stanford University, Stanford, California, USA; 3Stanford University, Stanford, USA

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                  2028.    Effects of Citalopram on Effective Connectivity During the Go/No-Go Task

 

Nia Goulden1, Shane McKie1, Rebecca Elliott1, Steve Williams1, Cristina Del-Ben2, John Frances William Deakin1, Ian Anderson1

1University of Manchester, Manchester, UK; 2University of Sao Paulo, Ribeirao Presto, Brazil

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                  2029.    Teasing Apart the Paced Auditory Serial Addition Task (PASAT): An fMRI Study

 

Shen-Hsing Annabel Chen1, Jessie Shuo-En Huang1, Jill Dorflinger2, Judi Zaferos2, Sally Durgerian2, Stephen M. Rao2

1National Taiwan University, Taipei, Taiwan; 2Medical College of Wisconsin, Milwaukee, Wisconsin, USA

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                  2030.    Joint Activation of the SMA and Pre-SMA During Simultaneous Motor and Language Tasks:

                              A Functional MRI Study

 

Kyung Peck1, Bob Hou1, Estee Psaty2, Michelle Bradbury3, Nicole Petrovich3, Andrei Holodny4

1Memorial Sloan-Kettering Cancer Center, New York, USA; 2Albert Einstein College of Medicine, New York; 3Memorial Sloan-Kettering Cancer Center, New York; 4Memorial Sloan-Kettering Cancer Center, New York, USA

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                  2031.    Can High Field Functional MRI Detect Interhemispheric Transfer of Visual and Motor Information?

 

Erin Lindsay Mazerolle1, 2, Ryan C N D'Arcy, 12, Chris V. Bowen, 12, Steven D. Beyea, 12

1Dalhousie University, Halifax, Nova Scotia, Canada; 2National Research Council, Halifax, Nova Scotia, Canada

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                  2032.    Neural Correlates of Cross Script Repetition Priming: An fMRI Study

 

Hyo Woon Yoon1, Kyungduk Cho2, Jun-Young Chung3, HyunWook Park

1Gachon University of Medicine and Science, Incheon, Republic of Korea; 2Paichai University, Daejeon, Republic of Korea; 3KAIST, Daejeon, Republic of Korea

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                  2033.    Motor Representations of Well-Practiced Handwriting Versus Novel Motor Sequences of

                              Graphomoto Output: An fMRI Study

 

Meirav Balas1, 2, David Manor3, Nir Giladi2, 4, Tammar Kushnir3, Avi Karni, 13

1Haifa University, Haifa, Israel; 2Tel-Aviv Sourasky Medical Center, Tel Aviv, Israel; 3The Chaim Sheba Medical Center, Tel Hashomer, Israel; 4Tel Aviv University, Tel Aviv, Israel

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                  2034.    Does the Modulation of the Insular Activity Affect Our Emotional Involvement? A Real-Time fMRI Study

                               During Emotional Pictures Processing

 

Andrea Caria1, Ranganatha Sitaram1, Ralf Veit1, 2, Niels Birbaumer1, 3

1University of Tübingen, Tübingen, Germany; 2Max Planck Institute for Biological Cybernetics, Tübingen, Germany; 3National Institute of Health (NIH), Bethesda, USA

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                  2035.    Meta-Analysis of fMRI Activation Associated with Response Inhibition During Performance of

                              Go/Nogo Tasks

 

Daniel Joseph Simmonds1, James J. Pekar1, 2, Stewart H. Mostofsky1, 2

1Kennedy Krieger Institute, Baltimore, Maryland, USA; 2Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

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                  2036.    Cervical Spinal fMRI Study: Modulation of Functional Activation Signal by Task Difficulty,

                              Hand Skill and Handedness

 

Man Cheuk Ng1, Ho Fai Lau1, E X. Wu1, E S. Yang2, y Hu2, D K. Luk2

1The University of Hong Kong, Pokfulam, Hong Kong; 2The University of Hong Kong, Pokfulam, Hong Kong

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                  2037.    Cognitive Coping Style Modulates Neural Responses to Emotional Faces – a 3T fMRI Study

 

Harald Kugel1, Astrid Veronika Rauch1, Patricia Ohrmann1, Jochen Bauer1, Almut Engelien1, Volker Arolt1, Walter Heindel1, Thomas Suslow1

1University of Muenster, Muenster, NRW, Germany

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                  2038.    Dissociating Bottom-Up Responses in the Amygdala from Top-Down Processing in the Orbitofrontal

                              Cortex Using an Event-Related Emotion Rating Paradigm

 

Paul Wright1, Dolores Albarracin1, Rick Donald Brown1, Hong Li1, G He1, Yijun Liu1

1University of Florida, Gainesville, Florida, USA

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                  2039.    Administration of Selective Serotonin Reuptake Inhibitors Changes Amygdala Activation

                              During Facial Emotion Processing

 

Christian Windischberger1, Rupert Lanzenberger1, Susanne Friedreich1, Christoph Spindelegger1, Alexander Holik1, Patrycja Stein1, Ulrike Moser1, Ewald Moser1, Siegfried Kasper1

1Medical University of Vienna, Vienna, Austria

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                  2040.    Functional Brain Correlates of Response Time Variability in Children

 

Daniel Joseph Simmonds1, Sunaina G. Fotedar1, Stacy J. Suskauer1, 2, James J. Pekar1, 2, Martha B. Denckla1, 2, Stewart H. Mostofsky1, 2

1Kennedy Krieger Institute, Baltimore, Maryland, USA; 2Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

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                  2041.    Learning Effects of Neurofeedback-fMRI on Neural Substrates Involved in Motor Imagery

 

Seung-Schik Yoo1, Jong-Hwan Lee1, Matthew Marzelli2, Ferenc A. Jolesz3, Lawrence P. Panych1

1Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA; 2Boston University, Boston, Massachusetts, USA; 3Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA

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                  2042.    Assessing the Influence of Negative Mood on Brain Processing of Visceral Sensation

 

Steven John Coen1, Martina Mitterschiffthaler1, Lloyd J. Gregory2, Lidia Yágüez1, Michael J. Brammer1, Steven CR Williams1, Qasim Aziz2

1Institute of Psychiatry, Kings College, London, UK; 2University of Manchester, UK

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                  2043.    Resting in Peace, Noise or with Instructions: The Influence of Scanner Background Noise on the

                               Default Mode of Brain Functions

 

Nadine Gaab1, Noa Ofen1, John DE Gabrieli1, Gary H. Glover2

1MIT, Cambridge, Massachusetts, USA; 2Stanford University, Stanford, California, USA

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                  2044.    Ingested Lipid Modulates Hypothalamic and Brainstem Neuronal Activity in Man: A phMRI Study

 

Shane McKie1, Daniel J. Lassman2, Lloyd J. Gregory2, Graham J. Dockray3, David G. Thompson2

1University of Manchester, Manchester, UK; 2Hope Hospital, Salford, UK; 3University of Liverpool, Liverpool, UK

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                  2045.    Altered Basal Ganglia Activation During Complex Finger Tapping Tasks in Patients with MS

 

Micheal D. Phillips1, Craig Israel Horenstein1, Lael Stone1, Ruth Ann Marrie1, Mark J. Lowe1

1Cleveland Clinic, Cleveland, Ohio, USA

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                  2046.    FMRI Reveals that Peak Activated Regions in the Primary Sensorimotor Cortex and Premotor

                              Regions are the Same for Multiple Sclerosis Patients and Controls During Complex Finger Tapping

 

Micheal D. Phillips1, Craig Israel Horenstein1, Lael Stone1, Ruth Ann Marrie1, Mark J. Lowe1

1Cleveland Clinic, Cleveland, Ohio, USA

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                  2047.    Measuring Variability in the BOLD Response to Interictal Epileptiform Discharges: An EEG/fMRI Study

 

Anthony B. Waites1, Danny Flanagan1, Richard A. Masterton1, David F. Abbott1, Graeme D. Jackson1

1Brain Research Institute, Heidelberg West, Vic, Australia

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                  2048.    Modelling Large Head Motion Events in fMRI Studies of Patients with Epilepsy

 

Louis Lemieux1, Afraim Salek-addadi1, Torben Ellegaard Lund2, Helmut Laufs1, David Carmichael1, Roman Rodionov1

1Institute of Neurology, University College London, London, UK; 2Danish Research Centre for MR, Denmark

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                  2049.    Identification of a Multivariate Biomarker of Alzheimer's Disease with ASL

 

Christian Habeck1, Iris Asllani1, Ajna Borogovac1, Nikolaos Scarmeas1, Truman Brown1, Yaakov Stern1

1Columbia University, New York, USA

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                  2050.    Limited Default Network in Bipolar Disorder by BOLD-Based fMRI

 

Sue-jin Lin1, Tzu-chen Yeh, 12, Chou-Ming Cheng2, Wen-Jui Kuo1, Jen-chuen Hsieh1, 2, Ton-ping Su, 12, Low-tone Ho, 12

1National Yang-Ming University, Taipei, Taiwan, Taiwan; 2Taipei Veterans General Hospital, Taipei, Taiwan, Taiwan

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                  2051.    Therapeutic Effect of Intensive Sensory Motor Integration Training in Children with ADHD: A Multimodal

                               Approach Using fMRI and VBM

 

Chien han Lai1, Tzu-chen Yeh, 12, Chou-ming Cheng2, Ming-hwei Yen3, Shin-Siung Jung4

1National Yang-Ming University, Taipei, Taiwan, Taiwan; 2Taipei Veterans General Hospital, Taipei, Taiwan, Taiwan; 3BioInno Health Technology, Taipei, Taiwan, Taiwan; 4Taiwan Research Institute of Learning Disability, Taipei, Taiwan, Taiwan

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                  2052.    Test-Retest Reproducibility of Cerebral and Subjective Responses to Painful and Non-Painful

                              Contact-Heat Evoked Potential Stimulation (CHEPS)

 

Matt A. Howard1, Steven J. Coen1, Tim J. Buchanan2, Trevor S. Smart2, Sarah L. Gregory1, John P. Huggins2, Magdi Hanna3, William Vennart2, Steven C R Williams1

1Institute of Psychiatry, London, UK; 2Pfizer, Sandwich, UK; 3Kings College Hospital, London, UK

 

 

High Resolution Brain Anatomy

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2053.    Tripping Over Ourselves to Image the Cerebellum

 

Sean CL Deoni1, 2, Marco Catani2

1Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, Oxford, England, UK; 2Institute of Psychiatry, London, England, UK

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                  2054.    Detection of the Stria of Gennari Using Turbo Spin Echo Imaging  at High Field

 

Rosa Maria Sanchez Panchuelo1, Stuart Clare2, Holly Bridge2, Richard Bowtell1, Sue Francis1

1University of Nottingham, Nottingham, UK; 2University of Oxford, Oxford, UK

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                  2055.    Signal Intensity of the Motor Cortex on Phase-Weighted Images at 3T

 

Mai Hanamiya1, Shingo Kakeda1, Junji Moriya1, Norihiro Ohnari1, Toru Sato1, Mika Kitajima2, Haque Hasnine3, Naoki Hirata3, Yukunori Korogi1

1University of Occupational and Environmental Health School of Medicine, Kitakyushu, Fukuoka, Japan; 2Department of Radiology, Kumamoto University School of Medicine; 3GE Yokogawa Medical Systems, Ltd,

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                  2056.    Sex Differences in the Mid-Sagittal Area of Corpus Callosum in the Human Brain Image

                              Obtained at 4.7T

 

Nobuhiro Takaya1, Hidehiro Watanabe1, Fumiyuki Mitsumori1

1National Institute for Environmental Studies, Tsukuba, Ibaraki, Japan

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                  2057.    Age-Related Changes of Normal Subthalamic Nucleus: Evaluation with High Resolution

                              MR Imaging at 3.0 T

 

Mika Kitajima1, Shingo Kakeda2, Junji Moriya2, Norihiro Ohnari2, Toru Sato2, Yoshiko Hayashida1, Toshinori Hirai1, Yasuyuki Yamashita1, Mitsuhiro Uike3, Yukunori Korogi2

1Kumamoto University, Kumamoto, Japan; 2University of Occupational and Environmental, Kitakyushu, Japan; 3GE Yokogawa Medial Systems, Japan

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                  2058.    Optimized High-Resolution Mapping of Magnetisation Transfer at 3 Tesla Reveals Substructures in the

                               Human Thalamus in Clinically Feasible Measurement Time

 

Gunther Helms1, Tabea Gringel1, Erck Elolf1, Walter Schulz-Schaeffer2, Peter Dechent1

1University of Göttingen, Faculty of Medicine, Göttingen, Germany; 2University of Göttingen, Faculty of Medicine, Germany

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                  2059.    Thalamo-Cortical Abnormalities Correlate with Thalamic Atrophy in CIS Patients at Presentation

 

Mason Shieh1, Daniel Pelletier1, SungWon Chung1, 2, Darin Okuda1, Roland G. Henry1, 2

1University of California at San Francisco, San Francisco, California, USA; 2University of California at Berkeley, Berkeley, California, USA

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                  2060.    Now That’s a Hippo! a Clinical Imaging Protocol for the Human Hippocampus at 7T

 

Jens Matthias Theysohn1, 2, Oliver Kraff1, 2, Stefan Maderwald1, 2, Armin de Greiff1, 2, Mark E. Ladd1, 2, Susanne C. Ladd1, 2, Elke Ruth Gizewski2, Michael Forsting2

1University Duisburg-Essen, Essen, Germany; 2University Hospital Essen, Essen, Germany

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                  2061.    Hippocampal Atrophy is the Critical Brain Change in Patients with Memory Disorder Resulting

                              from Anoxic Episode

 

Margherita Di Paola1, Lucia Fadda2, Laura Serra, Carlo Caltagirone2, Giovanni Augusto Carlesimo2

1Neuroimaging Laboratory, IRCCS S. Lucia Foundation, Rome, Italy, Italy; 2Department of Neurological Sciences, University of Rome “Tor Vergata”, Rome, Italy

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                  2062.    Quantitative Brain Tissue Mapping Using Fast Spin Echo Imaging

 

Robert Marc Lebel1, Luis Concha1, Christian Beaulieu1, Alan H. Wilman1

1University of Alberta, Edmonton, Alberta, Canada

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                  2063.    One Third of the Anterior Portion of the Optic Nerve Is Susceptible to Motion of Different Eye Direction

 

Michael G. Dwyer1, David A. Fritz1, Jennifer L. Cox1, Sonal Ambwani1, Erik Saluste2, Robert Matyas2, Robert Zivadinov1

1Buffalo Neuroimaging Analysis Center, Buffalo, New York, USA; 2Buffalo General Hospital, Buffalo, New York, USA

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                  2064.    Segmentation of Subtraction Images Yields Improvement in Reproducibility and Sensitivity of

                              Lesion Change Measurements in MS

 

Yang Duan1, 2, David F. Tate3, 4, Peter G. Hildenbrand3, 5, Istvan Csapo3, Dominik S. Meier3, Charles R.G. Guttmann3

1Brigham and  Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; 2The Second Clinical College & The Second Affiliated Hospital, China Medical University, Shenyang, Liaoning, People’s Republic of China; 3Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; 4Brown Medical School, Providence, Rhode Island, USA; 5Lahey Clinic, Burlington, Massachusetts, USA

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                  2065.    MR Imaging of a Postmortem Formalin-Fixed Human Brain of a Multiple Sclerosis Patient at 3T and 7T

 

Steffen Sammet1, Alayar Kangarlu2, Eric Bourekas1, Kottil W. Rammohan1, Regina Maria Koch1, Michael V. Knopp1

1The Ohio State University, Columbus, Ohio, USA; 2Columbia University, New York, New York, USA

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                  2066.    Sex Difference and Age Dependence of the Human Brain Structure Delineated at the High

                              Magnetic Field of 4.7T

 

Fumiyuki Mitsumori1, Nobuhiro Takaya1, Hidehiro Watanabe1

1Natl. Inst. Environ. Studies, Tsukuba, Ibaraki, Japan

 

 

Human Brain VBM

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2067.    Morphological Differences in the Grey Matters of Mathematicians: A Voxel-Based Morphometry Study

 

Ozlem Ozmen Okur1, Ayaz Agayev2, Cengizhan Ozturk3, Kubilay Aydin2, Adem Ucar,2 Kader Karli Oguz4

1Bogazici University Biomedical Engineering, Istanbul, Turkey; 2Istanbul University, Istanbul Medical School, Istanbul, Turkey; 3Bogazici University Biomedical Engineering, Istanbul, Turkey, 4Hacettepe University, Medical School, Ankara, Turkey

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                  2068.    The Similarity of the Brain in Healthy Monozygotic Twins: A Voxel Based Analysis of Volume,

                              T2 and DTI

 

Gaby S. Pell1, Regula S. Briellmann1, Kate Lawrence1, Debra Glencross1, Tony Waites1, Sam Berkovic1, Graeme D. Jackson1

1Brain Research Institute, W Heidelberg, VIC, Australia

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                  2069.    Haircut: A Method to Reduce the Dragging Effect Due to Smoothing in Voxel-Based Morphometry

 

Julio Acosta-Cabronero1, Joao Pereira1, Guy B. Williams1, Peter J. Nestor1

1University of Cambridge, Cambridge, UK

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                  2070.    Impact of Bias-Correction and Skull-Stripping Pipelines on Spatial Normalisation Using

                              SPM5 in a Phantom Model

 

Julio Acosta-Cabronero1, Guy B. Williams1, Peter J. Nestor1

1University of Cambridge, Cambridge, UK

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                  2071.    Magnetic Resonance Image Classification Via Over-Complete Independent Component Analysis and

                               Active Support Vector Machines

 

Clayton Chi-Chang Chen1, Jyh-Wen Chai2, Hsiang-Min Chen3, Tsung-Jung Li4, Yen-Chieh Ouyang3, Ching-Wen Yang1, San-Kan Lee5, Chein-I Chang6

1Taichung Veterans General Hospital, Taichung, Taiwan, Taiwan; 2Taichung VeteransGeneral Hospital, Taichung, Taiwan, Taiwan; 3National Chung Hsing University, Taichung, Taiwan, Taiwan; 4Chung Shan Medical University, Taichung, Taiwan, Taiwan; 5Yuanshan Veterans General Hospital, Yilan, Taiwan, Taiwan; 6University of Maryland, Baltimore County, Baltimore, Maryland, USA

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                  2072.    Improving Quantitative Analysis of Gray and White Matters in Brain Magnetic Resonance

                              Imaging Based on Coupling Independent Component Analysis with Support Vector Machines

 

Jyh-Wen Chai1, Clayton Chi-Chang Chen2, Hsiang-Min Chen3, Tsung-Jung Li4, Yen-Chieh Ouyang3, Ching-Wen Yang2, San-Kan Lee5, Chein-I Chang6

1Taichung VeteransGeneral Hospital, Taichung, Taiwan, Taiwan; 2Taichung Veterans General Hospital, Taichung, Taiwan, Taiwan; 3National Chung Hsing University, Taichung, Taiwan, Taiwan; 4Chung Shan Medical University, Taichung, Taiwan, Taiwan; 5Yuanshan Veterans General Hospital, Yilan, Taiwan, Taiwan; 6University of Maryland, Baltimore County, Baltimore, Maryland, USA

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                  2073.    Reproducibility of Segmented Brain Volumes Using SPM5: Effects of Changes in Signal-To-Noise

                              Ratio and Scanner Software

 

Borys Shuter1, 2, Berne Yeh1, Steven Graham2, Christopher Au1, Shih-Chang Wang1, 2

1National University Hospital, Singapore, Singapore; 2National University of Singapore, Singapore, Singapore

 

 

MR Techniques for Neuro:  Miscellaneous

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2074.    Blood-Pressure Dependent T2*-Mapping

 

Claus Kiefer1, Gerhard Schroth1, Roland Wiest1, Christoph Ozdoba1, Johannes Slotboom1, Luca Remonda1, Marwan ElKoussy1

1University Hospital, Bern, Switzerland

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                  2075.    Paramagnetic and Diamagnetic Cerebral Lesions in Susceptibility Weighted Phase Imaging (SWI)

 

Andreas Deistung1, Alexander Rauscher1, Hans-Joachim Mentzel1, Stephan Witoszynskyj1, Werner A. Kaiser1, Jürgen R. Reichenbach1

1Friedrich Schiller-University, Jena, Germany

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                  2076.    Susceptibility Weighted Imaging at 1.5T, 3T and 7T

 

Andreas Deistung1, Jan Sedlacik1, Alexander Rauscher1, Jörg Stadler2, Claus Tempelmann3, Johannes Bernarding3, Werner A. Kaiser1, Paul Müller1, Enrico Dittrich1, Jürgen R. Reichenbach1

1Friedrich Schiller-University, Jena, Germany; 2Leibniz Institute for Neurobiology, Magdeburg, Germany; 3Otto von Guericke University, Magdeburg, Germany

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                  2077.    Monitoring the Role and Metabolism of 13C-Hyperpolarized Steroids and Nonsteroidal

                              Anti-Inflammatory Drugs Via Parahydrogen-Enhanced MRI

 

Joachim Bargon1, Ute Bommerich2, Rahim Rizi3

1University of Bonn, Bonn, Germany; 2University of Magdeburg, Germany; 3University of Pennsylvania, Philadelphia, Pennsylvania, USA

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                  2078.    Hyperpolarizing and Exploring the Function of Drugs Used to Combat Epilepsy Via

                              Parahydrogen-Enhanced MRI

 

Joachim Bargon1, Ute Bommerich2, Rahim Rizi3

1University of Bonn, Bonn, Germany; 2University of Magdeburg, Germany; 3University of Pennsylvania, Philadelphia, Pennsylvania, USA

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                  2079.    Hyperpolarizing Drugs to Determine Their Role in Suppressing Epileptic Seizures and

                              Migraine Headaches Via MRI

 

Joachim Bargon1, Ute Bommerich2, Rahim Rizi3

1University of Bonn, Bonn, Germany; 2University of Magdeburg, Germany; 3University of Pennsylvania, Philadelphia, Pennsylvania, USA

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                  2080.    Verification of Susceptibility Difference and Volume Fraction for the Calculation of Oxygenation

                               Extraction Fraction Using Measurements of a Single Capillary and Network Phantom

 

Jan Sedlacik1, Alexander Rauscher1, Stephan Witoszynskyj1, Paul Müller2, Enrico Dittrich3, Werner A. Kaiser1, Jürgen R. Reichenbach1

1Friedrich Schiller Universität, Jena, Germany; 2Technische Univeristät Ilmenau, Ilmenau, Germany; 3Fachhochschule Jena, Jena, Germany

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                  2081.    Oxygen Effects in Tissue Preparation Neuronal Current MRI

 

Qingfei Luo1, Ho-Ling Liu2, Brent Parris1, Huo Lu3, David M. Senseman3, Jia-Hong Gao1

1University of Chicago, Chicago, Illinois, USA; 2Chang Gung University, Taiwan; 3University of Texas at San Antonio, San Antonio, Texas, USA

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                  2082.    Mapping BOLD Sensitivity to CO2 in the Human Brainstem

 

Kyle T S Pattinson1, Georgios D. Mitsis1, Ann K. Harvey1, Sharon Dirckx1, Stephen D. Mayhew1, Helen Hoar1, Richard Rogers1, Irene Tracey1, Richard G. Wise2

1Oxford University, Oxford, UK; 2Cardiff University, Cardiff, UK

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                  2083.    Decreased Glutamate Levels with Acute Exposure to Anesthetic Agent Propofol: A Preliminary

                               In Vivo 1H Spectroscopy Study

 

Jeffrey A. Stanley1, George M. Mckelvey1, Aliakei Pustavoitau2, Kerry Murphy1, Dalal Khatib1, Harold M. Marsh1, Matthew P. Galloway1

1Wayne State Univ Sch Med, Detroit, Michigan, USA; 2John Hopkins University, Baltimore, Maryland, USA

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                  2084.    Anesthetic Effects of Sevoflurane and Propofol on Regional CBF: A Comparative MRI Study on

                              Normal Subjects and Implications

 

Maolin Qiu1, Ramachandran Ramani1, Shu-Ming Wang1, Nallakandi Rajeevan1, Fuyuze S. Tokoglu1, Todd R. Constable1

1Yale University School of Medicine, New Haven, Connecticut, USA

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                  2085.    Brain Morphometry with Multiecho MPRAGE

 

Andre JW van der Kouwe1, Thomas Benner1, David H. Salat1, Bruce Fischl1, 2

1Massachusetts General Hospital, Charlestown, Massachusetts, USA; 2Massachusetts Institute of Technology, Cambridge, Massachusetts, USA

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                  2086.    Clinical Experience of the Use of Gadolinium Contrast Agents for T1-Weighted 3D High

                              Resolution Neurological Imaging

 

Terri Louise Watson1, Ulrika Estenberg1, Maria Kristoffersen Wiberg2

1Karolinska University Hospital, Huddinge, Stockholm, Sweden; 2Karolinska Institutet, Stockholm, Sweden

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                  2087.    High Contrast Imaging at High Field Strengths with Low SAR

 

Neelavalli Jaladhar1, Ewart Mark Haacke2

1Wayne State University, Detroit, Michigan, USA; 2Wayne State University, Michigan, USA

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                  2088.    Contrast Between Grey and White Matter in 7 T Phase Images and Its Potential for Segmentation

 

Andreas Schäfer1, Penny A. Gowland1, Richard W. Bowtell1

1University of Nottingham, Nottingham, UK

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                  2089.    A Robust Spherical Inflation Technique Using the Method of Concentric Rings

 

Min Jeong Kwon1, Jooyoung Hahn1, HyunWook Park1

1Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea

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                  2090.    Automatic Segmentation of Human Brain, Grey and White Matter in MRI: A Robust and Accurate

                               Algorithm Based on the Tissues' Features Analysis

 

Manfredo Atzori1, Gianluca Rambaldelli1, Cinzia Perlini1, Marcella Bellani1, Nicola Dusi1, Silvia Sponda1, Michele Tansella1, Paolo Brambilla2

1University of Verona, Verona, Italy; 2University of Udine, Udine, Italy

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                  2091.    Automatic Measurements of Brain Tissue Volumes and Volume Distributions

 

Erin Jane McCormack-Kelly1, Sachin Jambawalikar2, Michael R. Egnor3, Zengmin Yan3, Mark E. Wagshul3

1Stony Brook University, Coram, New York, USA; 2Stony Brook University, Stony Brook, New York; 3Stony Brook University, Stony Brook, New York, USA

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                  2092.    Quantitation of Brain Tissue Swelling Using MRI

 

Rebecca J. Theilmann1, Edward Dyer1, Susan R. Hopkins1, Richard B. Buxton1, David J. Dubowitz1

1University of California San Diego, La Jolla, California, USA

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                  2093.    T1 Mapping to Identify Changes in Cortical Structure

 

Nurunisa Neyzi1, Stuart Clare2, Sean Deoni2

1Weill Cornell Medical College, New York, New York, USA; 2Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, Oxford University, Oxford, UK

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                  2094.    Diagnostic Features of Acute DWI Abnormalities of Different Origin in the Hippocampus

 

Kristina Szabo1, Rolf Kern1, Martin Griebe1, Simone Bukow1, Alex Förster1, Michael G. Hennerici1, Achim Gass1

1Universitätsklinikum Mannheim; University of Heidelberg, Mannheim, Germany

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                  2095.    Structural Correlates of Implicit Memory Learning Deficits in Developmental Dyslexia

 

Deny Menghini1, 2, Gisela Hagberg2, Stefano Vicari1, 3, Laura Petrosini, 24, Emiliano Macaluso2, Carlo Caltagirone2, 5, Marco Bozzali2

1IRCCS, Children’s Hospital “Bambino Gesù”, Santa Marinella, Rome, Italy; 2Santa Lucia Foundation, Rome, Italy; 3University LUMSA, Rome, Italy; 4University “La Sapienza”, Rome, Italy; 5University Tor Vergata, Rome, Italy

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                  2096.    Chronic and Incremental Effect of Hypoxia Due to Extreme High-Altitude Exposure Relate with

                               Atrophy in Motor-Function Related Brain Areas

 

Margherita Di Paola1, Marco Bozzali1, Lucia Fadda2, Massimo Musicco3, Umberto Sabatini1, Carlo Caltagirone2

1Neuroimaging Laboratory, IRCCS S. Lucia Foundation, Rome, Italy, Italy; 2Department of Neurological Sciences, University of Rome “Tor Vergata”, Rome, Italy; 3National Research Council. Institute of Biomedical Technologies. Milan Italy. Ev-K2-CNR, Milan, Italy

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                  2097.    Subcortical Physiological Abnormalities in Type 2 Diabetes Detected Using Magnetization Transfer

 

Anand Kumar1, R.K. Gupta2, Olusola Ajilore1, Ebrahim Haroon3, Genevieve Rodriguez1, Albert Thomas2

1UCLA Semel Institute, Los Angeles, California, USA; 2UCLA, Los Angeles, California, USA; 3Emory University, Atlanta, Georgia, USA

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                  2098.    Polymorphic Deletion in DCDC2 Affects Brain Morphology - A Voxel Based Morphometric Study

 

Shashwath A. Meda1, Jeffrey R. Gruen2, Vince D. Calhoun2, 3, Joel Gelernter2, Haiying Meng2, Godfrey D. Pearlson1, 2

1Hartford Hospital, Hartford, Connecticut, USA; 2Yale University, New Haven, Connecticut, USA; 3University of New Mexico, Albuquerque, New Mexico, USA

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                  2099.    Cross-Sectional and Longitudinal Brain Morphometry in HIV Associated Cognitive Impairment

 

Ying Wu1, Pippa Storey2, Bruce Cohen, Leon Epstein, Robert Edelman2, Ann Ragin

1Evanston Northwestern Healthcare; Feinberg School of Medicine, Northwestern University., Evanston, Illinois, USA; 2Evanston Northwestern Healthcare; Feinberg School of Medicine, Northwestern University., Illinois, USA

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                  2100.    Brain Tissue Water Content Measured by MRI: Pre- Vs. Post-Shunt Chronic Hydrocephalus

 

XIAODONG GUO1, JIA-HONG GAO2, Richard D. Penn1

1University of Chicago, Chicago, Illinois, USA; 2University of Chicago, Chicago, Illinoise, USA

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                  2101.    Structural Brain Deficits in Smokers Measured by MR Volumetry at 3 T

 

Florian Schubert1, Frank Seifert1, Mario Staedtgen2, Jürgen Gallinat2

1Physikalisch-Technische Bundesanstalt, Berlin, Germany, Germany; 2Charite Universitätsmedizin, Berlin, Germany, Germany

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                  2102.    Brain MRI of Moving Subjects: Snapshot Images with Volume Reconstruction (SVR) Extended to

                              Multi-Shot Sequences and Applied to Neonates and Adults

 

Shuzhou Jiang1, Hui Xue1, Mary A. Rutherford1, Adam Waldman1, Kate McLeish2, Derek Hill2, Daniel Rueckert, Joseph V. Hajnal1

1Hammersmith Hospital, Imperial College London, London, UK; 2University College London, London, UK

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                  2103.    T2 Relaxation Illustrates Correlation Between Myelin Development and Verbal  IQ Scores in

                              Young Males

 

Kirstie Whitaker1, Campbell M. Clarke1, Alex L. MacKay1

1University of British Columbia, Vancouver, BC, Canada

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                  2104.    Null Point Imaging

 

John James Totman1, Penny A. Gowland1, Alain Pitiot1

1University of Nottingham, Nottingham, UK

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                  2105.    The ADNI Phantom and Analysis Algorithm: A New and Accurate Tool to Measure Scanner Performance

 

Jeffrey L. Gunter1, Paula J. Britson1, Joel P. Felmlee1, Chadwick P. Ward1, Norbert Schuff2, Michael Weiner2, Josh Levy3, Clifford R. Jack,Jr. 1

1Mayo Clinic and Foundation, Rochester, Minnesota, USA; 2UC SanFrancisco, SanFrancisco, California, USA; 3The Phantom Laboratory, Salem, New York, USA

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                  2106.    Estimation of Fractional Contributions of White and Gray Matter by Cross-Regularized Inverse

                              Laplace Transform

 

Christian Labadie1, Silvia Jarchow2, Harald E. Möller3

1905 chemin des Genêts, Saint-Dié, France; 2Riensbergerstr. 82, Bremen, Germany; 3Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany

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                  2107.    Morphometry of the Retrobulbar Human Optic Nerve: Comparison of 3T MRI with

                              Conventional Sonography

 

Thorsten Alexander Bley1, Mathias Weigel1, Wolf Lagreze1, Alexander Lazzarro1, Alex Frydrychowicz1, Mathias Langer1, Juergen Hennig1

1University of Freiburg, Freiburg, Baden-Wuerttemberg, Germany

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                  2108.    Towards Quantitative Magnetic Resonance "Angstromscopy"

 

Sean CL Deoni1, 2, Catherine Traynor2

1Oxford Centre for Functional Magnetic Resonance Imaging of the Brain, Oxford, England, UK; 2Institute of Psychiatry, London, England, UK

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                  2109.    A Comparison of T2- And T2*-Weighted Imaging at 7T

 

Christopher John Wiggins1, Graham Charles Wiggins1, Christina Triantafyllou1, Lawrence Wald1, Alma Gregory Sorensen1

1Massachusetts General Hospital, Charlestown, Massachusetts, USA

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                  2110.    Contrast Enhanced MR Imaging of the Brain Using T1-FLAIR with BLADE Compared with

                              Conventional Spin Echo Sequence

 

Shinji Naganawa1, Hisashi Kawai1, Hiroshi Fukatsu1

1Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan

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                  2111.    Geometric Reconstruction of Brain Vasculature from Small Rodents; a Comparison of Different

                              Imaging Methods

 

Manuel Gaudnek1, Michael Siblia1, 2, Klaus Obermayer1, 3, Brune Kay4, Andreas Hess4

1Berlin University of Technology, Berlin, Germany; 2Bernstein Centre for Computational Neuroscience, Berlin, NA, Germany; 3Bernstein Centre for Computational Neuroscienc, Berlin, NA, Germany; 4I. f. Experimental Pharmacology, Erlangen, NA, Germany

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                  2112.    Evaluation of Anterior Choroidal Artery on 3T 3D TOF MRA

 

Yoshiyasu Hiratsuka1, Hitoshi Miki1, Keiichi Kikuchi1, Ikuko Kiriyama1, Teruhito Mochizuki1, Shizue Takahashi2, Ichiro Matsubara2, Kazuhiko Sadamoto2

1Ehime University School of Medicine, Toon, Ehime, Japan; 2Washo-kai Sadamoto Hospital, Matsuyama, Ehime, Japan

 

 

Motion Artifact Suppression - Brain

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2113.    Detection and Measurement of Data Loss Due to MRI Interleave Positioning Errors

 

Roger Tam1, Andrew Riddehough1, Guojun Zhao1, Anthony Traboulsee1, David Li1

1University of British Columbia, Vancouver, British Columbia, Canada

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                  2114.    Motion Artifacts for Diffusion Spectrum Imaging

 

Wen-Yang Chiang1, Van J. Wedeen2, Timothy G. Reese3, Wen-Yih Isaac Tseng1

1National Taiwan University College of Medicine, Taipei, Taiwan; 2Harvard Medical School, Charlestown, Massachusetts, USA; 3Massachusetts General Hospital, Boston, Massachusetts, USA

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                  2115.    Improvement of DTI Measurement Accuracy Using Real-Time Navigated Data Acquisition

 

XIANFENG SHI1, Eugene Kholmovski2, Seong-Eun Kim2, Dennis L. Parker2, Eun-Kee Jeong2

1University of Utah, salt lake city, Utah, USA; 2University of Utah, Salt Lake City, Utah, USA

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                  2116.    High-Quality Non-Water Suppressed MR Spectra with Correction for Motion Induced Signal Reduction

 

Jyh-Miin Lin1, Shang-Yueh Tsai1, Chou-Ming Cheng2, Tzu-Chen Yeh2, Hua-Shan Liu1, 3, Robert V. Mulkern4, Hsiao-Wen Chung1, Nan-Kuei Chen5

1National Taiwan University, Taipei, Taiwan; 2Taipei Veterans General Hospital, Taipei, Taiwan; 3Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan; 4Children's Hospital and Harvard Medical School, Boston, Massachusetts, USA; 5Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA

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                  2117.    Motion Insensitive 3D Imaging Using a Novel Real-Time Image-Based 3D PROspective

                              MOtion Correction Method (3D PROMO)

 

Ajit Shankaranarayanan1, Cooper Roddey2, Nathan White2, Eric T. Han3, Daniel Rettmann4, Juan Santos5, Ehud Schmidt6, Anders Dale2

1GE Healthcare, Bethesda, Maryland, USA; 2University of California San Diego, San Diego, California, USA; 3GE Healthcare, Menlo Park, California, USA; 4GE Healthcare, Rochester, Minn, USA; 5Stanford University, Palo Alto, California, USA; 6GE Healthcare, Boston, Massachusetts, USA

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                  2118.    Optimization of Hybrid 2-Dimensional Navigator Correction to Suppress

                              Respiratory-Induced Physiological Noise

 

Robert L. Barry1, 2, L. M. Klassen1, Ravi S. Menon1, 2

1Robarts Research Institute, London, Ontario, Canada; 2University of Western Ontario, London, Ontario, Canada

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                  2119.    Prospective Correction of Large Simple Through-Plane Motion

 

Sara Elizabeth Yancey1, Fred Tam2, Kevan James Thompson Anderson1, Labonny Biswas3, Graham A. Wright1, Simon J. Graham1, 4

1University of Toronto, Toronto, Ontario, Canada; 2Sunnybrook Hospital, Toronto, Ontario, Canada; 3The Hospital for Sick Children, Toronto, Ontario, Canada; 4Baycrest Hospital, Toronto, Ontario, Canada

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                  2120.    Ballistocardiogram Artifact Removal from EEG Signals Using the Real-Time Kalman Filter

 

Myung Ho In1, Hyun Chung Kim1, Tae Seok Park1, Tae-Seong Kim1, Min Hyoung Cho1, Soo Yeol Lee1

1Kyung Hee University, Yongin, Kyungki, Republic of Korea

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                  2121.    A Multi-Echo Approach to Removing Task-Correlated Motion Artefacts in fMRI

 

Pieter François Buur1, David Gordon Norris1

1F.C. Donders Centre for Cognitive Neuroimaging, Nijmegen, Netherlands

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                  2122.    The Effects of Slice-Timing and the Use of Registration Parameters as Covariates in the Analysis of

                               fMRI Experiments Exhibiting Either Task-Correlated Motion or Residual Motion from Image-Based

                               Motion Tracking.

 

Sebastiaan Gobets1, Jan-Henry Seppenwoolde1, Suzanne Koudijs1, Josien Pluim1, Matthias J.P. van Osch2

1University Medical Center Utrecht, Utrecht, Netherlands; 2Leiden University Medical Center, Leiden, Netherlands

 

 

Diffusion Imaging of Neurodegenerative Diseases

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2123.    Progressive White Matter Microstructural Changes Following Mild Traumatic Brain Injury Revealed

                              by Bootstrap Analysis of Serial 3T Diffusion Tensor MRI

 

SungWon Chung1, 2, Hana Lee2, Srivathsa Veeraraghavan2, Duan Xu2, Michele Meeker2, Jamshid Ghajar3, Geoffrey T. Manley2, Roland G. Henry1, 2, Pratik Mukherjee1, 2

1University of California San Francisco & Berkeley, San Francisco, California, USA; 2University of California San Francisco, San Francisco, California, USA; 3Brain Trauma Foundation, New York, New York, USA

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                  2124.    Improved Distortion Correction in Cerebral and Spinal DTI Using Interleaved Reversed Gradients

 

Man Cheuk Ng1, Seth A. Smith2, 3, Joseph S. Gillen2, 3, Bennett A. Landman2, D K. Luk4, y Hu4, Peter C.M. van Zijl2, 3, E S. Yang4

1The University of Hong Kong, Pokfulam, Hong Kong; 2Johns Hopkins University, Baltimore, Maryland, USA; 3Kennedy Krieger Institute, Baltimore, Maryland, USA; 4The University of Hong Kong, Pokfulam, Hong Kong

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                  2125.    Brain Diffusion Weighted Imaging Study of Friedreich Ataxia Patients

 

Raffaele Lodi1, Giovanni Rizzo1, Caterina Tonon1, David Manners1, Emil Malucelli1, Filippo Fortuna1, Claudia Testa1, Barbara Mostacci1, Antonella Pini2, Valerio Carelli1, Bruno Barbiroli1

1Università di Bologna, Bologna, Italy; 2U.O. Neuropediatria, Ospedale Maggiore, Bologna, Italy

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                  2126.    Diffusion Tensor Imaging in Parkinsonism – Analysis of Corticospinal Tracts and Association Bundles

                               in Patients with Essential Tremor Vs Parkinson´s Disease by Quantitative Spatially Normalized

                               DTI at 3.0T

 

Heiner Matthias Stiepani1, Alexander Hopt2, Michail Plotkin, Harald Bruhn1, Zhun Kyung-Hee1, Andreas Kupsch2, Soren Gartenschlager1, Florian Streitparth1, Karl Titus Hoffmann1

1Charite Virchow, Berlin, Germany; 2Charite,

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                  2127.    Increased Brain Diffusion in the Genu of HIV Patients at One-Year Follow-Up

 

Victoria Wong1, Linda Chang1, Helenna Nakama1, Michael Watters1, Christine Cloak1, Darlene Ramones1, Thomas Ernst1

1University of Hawaii, John A. Burns School of Medicine, Honolulu, Hawaii, USA

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                  2128.    DTI VBM Analysis of Pathological Progression in HIV Patients Underwent Associated Dementia

 

Tong Zhu1, Michelle Gaugh1, Kim Cruttenden1, David Gill1, Kevin Biglan1, Jianhui Zhong, 12, Giovanni Schifitto1

1University of Rochester, Rochester, New York, USA; 2University of Rochesterr, Rochester, New York, USA

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                  2129.    White Matter Changes in Chronic Cocaine Users Revealed by Voxelwise Group Analysis of

                              Diffusion Tensor Imaging

 

Wang Zhan1, Hong Gu1, Thomas J. Ross1, Betty Jo Salmeron1, Elliot A. Stein1, Yihong Yang1

1National Institute on Drug Abuse, Baltimore, Maryland, USA

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                  2130.    DTI-Based Analysis Facilitates the Understanding of a Peculiar Neuropsychological Dissociation

                              in a Patient with Bilateral Thalamic Damage

 

Andrea Cherubini1, Giovanni Augusto Carlesimo, 12, Laura Serra1, Lucia Fadda, 12, Marco Bozzali1

1Santa Lucia Foundation, Rome, Italy; 2Tor Vergata University, Rome, Italy

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                  2131.    Selective Damage of the Visual Pathways in Patients with Migraine: A MR Tractography Study at 3 T

 

Maria Assunta Rocca1, Elisabetta Pagani1, Paola Tortorella1, Bruno Colombo1, Andrea Falini1, Giuseppe Scotti1, Giancarlo Comi1, Massimo Filippi, 12

1Scientific Institute and University Ospedale San Raffaele, Milan, Italy; 2Scientific Institute and University, Hospital San Raffaele, Milan, Italy, Italy

 

 

Brain Degeneration:  Ataxias & Dementias

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2132.    Assessment of Oxidative Stress and Neuronal Viability in Friedreich’s Ataxia by 1H MRS at 4 Tesla

 

Gulin Oz1, Isabelle Iltis1, Diane Hutter1, Christopher M. Gomez2

1University of Minnesota, Minneapolis, Minnesota, USA; 2University of Chicago, Chicago, Illinois, USA

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                  2133.    Diffusivity and Diffusion Anisotropy of Cerebellar Peduncles in the Cases of Spinocerebellar Ataxia. -                              Short-Range Tractography Based Analysis in Order to Avoid Crossing Fiber Problem-

 

Toshiaki Taoka1, Tesseki Kin1, Hiroyuki Nakagawa1, Masahiko Sakamoto1, Satoru Iwasaki2, Makito Hirano1, Satoshi Ueno1, Kimihiko Kichikawa1

1Nara Medical University, Kashihara, Nara, Japan; 2Higashiosaka City General Hospital, Higashiosaka, Osaka, Japan

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                  2134.    Decreased Anisotropy in the Corpus Callosum of Patients Suffering from Limb Kinetic Apraxia

 

Jan-Hendrik Buhk1, Matthias Küntzel2, Kai Kallenberg1, Jens Frahm2, Walter Paulus1, Peter Dechent1

1University of Göttingen, Göttingen, Germany; 2Max-Planck-Institut für biophysikalische Chemie, Göttingen, Germany

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                  2135.    Characterization of Cerebellar Metabolic Alterations in Ataxia with Oculomotor Apraxia (AOA2)

 

Isabelle Iltis1, Diane Hutter1, Christopher M. Gomez2, Gulin Oz1

1University of Minnesota, Minneapolis, Minnesota, USA; 2University of Chicago, Chicago, Illinois, USA

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                  2136.    Quantitative SWI in Differentiation of MSA and Parkinson's Disease

 

Feng Feng1, Hui You1, Han Wang1, Hao Shen2, Fuling Zheng1, Hongyi Sun1, Zhengyu Jin1

1Peking Union Medical College Hospital, Beijing, People’s Republic of China; 2GE Healthcare China, Beijing, People’s Republic of China

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                  2137.    Diffusion Weighted Imaging Differentiates Corticobasal Degeneration from Progressive

                              Supranuclear Palsy and Parkinson’s Disease

 

Giovanni Rizzo1, 2, David Neil Manners1, Caterina Tonon1, Cesa Scaglione2, Barbara Mostacci1, Emil Malucelli1, Valerio Maruotti2, Paolo Martinelli2, Raffaele Lodi1, Bruno Barbiroli1

1Bologna University, Bologna, Italy; 2University of Bologna, Bologna, Italy

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                  2138.    31P MRS of the Brain Supports the Mitochondrial Hypothesis for Huntington Disease, Revealing

                              Altered ATP Synthesis, pH Increase and Stable ATP Level

 

Myriam Chaumeil1, Hélène Bataille1, Julien Valette1, Emmanuel Brouillet1, Véronique Gaura1, Anne Catherine Bachoud-Levi2, Pierre Krystkowiak3, Christophe Verny4, Philippe Damier5, Amandine Rialland2, Gilles Bloch1, Philippe Hantraye1, Philippe Remy1, 2, Vincent Lebon1, 6

1CEA-CNRS, Orsay, France; 2CHU Henri Mondor, Créteil, France; 3CHRU Roger Salengro, Lille, France; 4CHRU Larrey, Angers, France; 5CHRU Guillaume et Rene Laënnec, Nantes, France; 6CEA-NeuroSpin, Gif-sur-Yvette, France

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                  2139.    First Study of Therapy Follow-Up of Creutzfeldt-Jakob Disease by Magnetic Resonance

                              Diffusion and Spectroscopy

 

Danielle Ibarrola1, Alain Vighetto2, Pierre Krolak-Salmon2, Marc Hermier3, Jean-Claude Froment3, Dominique Sappey-Marinier1, 4

1IFR19, CERMEP - Imagerie du vivant, Bron, France; 2Neurologie, Hôpital Neurologique, Bron, France; 3Neuroradiologie, Hôpital Neurologique, Bron, France; 4CREATIS CNRS UMR5515 & INSERM U630 - Université Claude Bernard, Lyon, France

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                  2140.    3 Tesla MR Spectroscopy Reveals Decreased Glutamate and Glutamine Levels in Frontal

                              White Matter in HIV-Associated Dementia

 

Mona A. Mohamed1, Ned C. Sacktor1, Richard L. Skolasky1, Richard T. Moxley1, Martin G. Pomper1, Peter B. Barker1

1Johns Hopkins University Sch of Med, Baltimore, Maryland, USA

 

 

Alzheimer's Disease Imaging

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2141.    Towards a 10 Minute Clinical Alzheimer MR Imaging Protocol

 

Gunnar Krueger1, Hubertus Fischer2, Karsten Jahns2, Daniel Driemel2, Arne Littmann2, Stephan Kannengiesser2, Alma Greg Sorensen3, Matt A. Bernstein4, Paula J. Britson4, Chadwick P. Ward4, Jeffrey L. Gunter4, Denise A. Reyes4, Clifford R. Jack Jr. 4

1Siemens Medical Solutions, Lausanne, Switzerland; 2Siemens Medical Solutions, Erlangen, Germany; 3Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA; 4Mayo Clinic and Foundation, Rochester, Minnesota, USA

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                  2142.    Whole Brain Atrophy Rate in Relation to Cognitive Decline in Alzheimer’s Disease and

                              Mild Cognitive Impairment

 

Jasper D. Sluimer1, Wiesje M. van der Flier1, Nick C. Fox2, Philip Scheltens1, Frederik Barkhof1, Hugo Vrenken1

1VU Medical center, Amsterdam, Netherlands; 2University College London, UK

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                  2143.    Degeneration of Subcortical White Matter in Alzheimer's Disease: Topographical Analysis

 

Takashi Yoshiura1, Tomoyuki Noguchi1, Akio Hiwatashi1, Osamu Togao1, Koji Yamashita1, Seiji Kumazawa1, Futoshi Mihara1, Hiroshi Honda1

1Kyushu University, Fukuoka, Japan

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                  2144.    Local Volumetric Analysis of the Brain Ventricles in Alzheimer's Disease Using MRI

 

Hans Olofsen1, Luca Ferrarini1, Walter Miguel Palm, Mark A. van Buchem, Johan H.C. Reiber1, Faiza Admiraal-Behloul1

1LKEB - Leiden University Medical Center, Leiden, Netherlands

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                  2145.    Automated Hippocampal Volumetry in Alzheimer’s Disease, Mild Cognitive Impairment and

                              Normal Aging

 

Olivier Colliot1, Gaël Chételat2, Marie Chupin1, 3, Béatrice Desgranges2, Dominique Hasboun1, Bruno Dubois4, Stéphane Lehéricy4, 5, Francis Eustache2, 6, Line Garnero1, 7

1CNRS - Université Pierre et Marie Curie Paris 6 - Hôpital de la Pitié-Salpêtrière, Paris, France; 2Inserm-EPHE-Université de Caen Basse-Normandie, Unité E 0218, GIP Cyceron, CHU de Caen, Caen, France; 3Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London, UK; 4INSERM U610, Université Pierre et Marie Curie - Paris 6, Hôpital de la Pitié-Salpêtrière, Paris, France; 5IFR 49; 6EPHE, CNRS UMR 8581, Université René Descartes, Paris, France; 7IFR 70,

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                  2146.    Quantitative T2 Relaxation of White Matter Hyperintensities in Probable Alzheimer Patients

 

Wendy Oakden1, Nancy Lobaugh1, Sandra Black1, Greg Jan Stanisz1

1Sunnybrook HSC, Toronto, Ontario, Canada

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                  2147.    Association of Regional Atrophy, MRI-Guided SPECT Perfusion, and Memory Performance in

                              Patients with Mild Cognitive Impairment Compared to Healthy Elderly Controls

 

Min-Ying Su1, Huali Wang2, Rahyeong Juh1, Ke Nie1, Yong Chu1, Alberto Bert1, Mark Mandelkern3, Orhan Nalcioglu1

1University of California, Irvine, California, USA; 2Peking University Institute of Mental Health, Beijing, People’s Republic of China; 3University of California, Irvine, California, USA

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                  2148.    Preliminary Cross-Sectional MRI-Derived ROI-Based Analysis of PET Data from the Alzheimer’s

                              Disease Neuroimaging Initiative

 

David S. Karow1, Christine Fennema-Notestine2, Donald J. Hagler Jr. 2, Elaine Wu2, James B. Brewer2, Adam S. Fleisher2, Eric T. Han3, Carl K. Hoh2, Anders M. Dale2

1University of California, San Diego, La Jolla, California, USA; 2University of California, San Diego, California, USA; 3GE Healthcare, Menlo Park, California, USA

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                  2149.    Conserved Patterns of White Matter Hyperintensity Distribution in Alzheimer's, Cerebral

                              Amyloid Angiopathy, and Healthy Aging

 

Christopher Michael Holland1, 2, Eric E. Smith3, Istvan Csapo1, M. Edip Gurol3, Douglas A. Brylka1, Charles R. G. Guttmann1, Steven Mark Greenberg3

1Brigham and Women's Hospital, Boston, Massachusetts, USA; 2Boston University School of Medicine, Boston, Massachusetts, USA; 3Massachusetts General Hospital, Boston, Massachusetts, USA

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                  2150.    Is a Progressive Increase in the Number of Microhemorrhages in the Aged an Earlier
                             Sign of Alzheimer’s Disease?

 

E. Mark Haacke1, 2, Muhammad Ayaz1, Alexander S. Boikov2, Bharani Krishnamurthy1, Elena S. Manova1, April Dickson3, Cindy Dickson3, Wahed Baqai3, William Britt3, Wolff Kirsch3, Daniel Kido3, Floyd Petersen3

1Wayne State University, Detroit, Michigan, USA; 2MRI institute for biomedical researchers, Detroit, Michigan, USA; 3Loma Linda University, Loma Linda, California, USA

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                  2151.    Effects of Cardiovascular Disease Risk Factors on Regional Cerebral Blood Flow in Dementia

 

Weiying Dai1, Oscar L. Lopez1, Owen T. Carmichael2, James T. Becker1, Lewis H. Kuller1, H Michael Gach, 13

1University of Pittsburgh, Pittsburgh, Pennsylvania, USA; 2University of California, Davis, California, USA; 3Nevada Cancer Institute, Las Vegas, Nevada, USA

 

 

Imaging of Aging:  Adolescents to Elders

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2152.    Evaluating Structural Brain Changes in Adolescence with Magnetic Resonance
                              Imaging and Deformation Based Morphometry

 

William R. Riddle1, Susan C. DonLevy1, Curtis A. Wushensky1, Benoit M. Dawant1, J Michael Fitzpatrick1, Ronald R. Price1

1Vanderbilt University, Nashville, Tennessee, USA

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                  2153.    In Vivo Imaging of Myelin Development in Young Males Using T2 Relaxation

 

Kirstie Whitaker1, Campbell M. Clarke1, Alex L. MacKay1

1University of British Columbia, Vancouver, BC, Canada

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                  2154.    Microstructure in Subcortical White Matter in Individual Cortical Regions: Age-Related Changes
                             After Adolescence

 

Takashi Yoshiura1, Tomoyuki Noguchi1, Akio Hiwatashi1, Osamu Togao1, Koji Yamashita1, Seiji Kumazawa1, Futoshi Mihara1, Hiroshi Honda1

1Kyushu University, Fukuoka, Japan

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                  2155.    Relationship Between Body Fat Composition and Concentrations of Brain N-Acetyl-Aspartate
                              and Choline Compounds in Middle-Aged Adults

 

Stefan Gazdzinski1, John Kornak2, Michael W. Weiner2, 3, Dieter Johannes Meyerhoff2

1Northern California Institute for Research and Education, San Francisco, California, USA; 2University of California, San Francisco, California, USA; 3CIND, San Francisco, California, USA

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                  2156.    The Age and Gender Dependence of Total Transverse Relaxation Rate in Normal Human Brain at 3 T

 

Jianli Wang1, Xiaoyu Sun1, Erin Zimmerman1, Michael B. Smith1, Jianzhong Yin2, Ji Qi2, Qing X. Yang1

1Penn State College of Medicine, Hershey, Pennsylvania, USA; 2Tianjin First Central Hospital, Tinjin, People’s Republic of China

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                  2157.    Multivariate-Defined Spatial Networks of Age-Associated Atrophy

 

Adam M. Brickman1, Christian Habeck1, Marco A. Ramos1, Joseph Flynn1, Yaakov Stern1

1Columbia University, New York, New York, USA

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                  2158.    Age Dependence in Phase Images of Human Brain at 3T and 7T: Implications for 
                             High Field Contrast Mechanisms

 

Georgeta Mihai1, Amir M. Abduljalil1, Peter A. Wassenaar1, Donald W. Chakeres1, Michael V. Knopp1, Petra Schmalbrock1

1The Ohio State University, Columbus, Ohio, USA

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                  2159.    Decline in Extent Macroscopic Cerebral Vasculature with Age Quantified Using
                              Computerized Automatic Vessel Tracking

 

James Myers1, Hui Xue1, Adam Waldman2, Daniel Rueckert, Jo Hajnal1

1Hammersmith Hospital, Imperial College London, London, UK; 2Charing Cross Hospital, London, UK

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                  2160.    DTI and MTI Parameters Correlate in Periventricular White Matter Hyperintensities in Old Age

 

Mark E. Bastin1, Jonathan D. Clayden1, Alison Pattie1, Iona F. Gerrish1, Joanna M. Wardlaw1, Ian J. Deary1

1University of Edinburgh, Edinburgh, Mid Lothian, UK

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                  2161.    Tensor-Based Morphometry and Classifier Algorithms for the Identification of Structural
                              Brain Changes in Geriatric Depression

 

Promiti Dutta1, Robert Tamburo1, Minjie Wu1, Meryl Butters1, Charles Reynolds1, Howard Aizenstein1

1University of Pittsburgh, Pittsburgh, Pennsylvania, USA

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                  2162.    Working Memory as a Function of Cognitive Decline in Old Age: An fMRI Study

 

Gordon D. Waiter1, Helen C. Fox1, Alison D. Murray1, John M. Starr2, Ian J. Deary2, Lawrence J. Whalley1

1University of Aberdeen, Aberdeen, UK; 2University of Edinburgh, Edinburgh, UK

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                  2163.    Attention Inhibitory Process Decline During Life Span: A Functional MRI Study

 

Alexandre MATHIS1

1FORENAP, ROUFFACH, France

 

 

Brain Iron Imaging

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2164.    Evaluation of Brain Iron In Vivo with Susceptibility Weighted Imaging

 

Xiaojun Xu1, Qidong Wang1, Minming Zhang1, Guang Cao2

1First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China; 2GE Healthcare China,

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                  2165.    Brain Iron in MR Imaging: R2* and Phase Shift at Different Field Strengths

 

Bing Yao1, Peter van Gelderen1, Jacco A. de Zwart1, Jeff H. Duyn1

1National Institutes of Health, Bethesda, Maryland, USA

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                  2166.    Association of Neurodegenerative Markers with T2 Hypointensities in the Basal Ganglia

 

Jeroen van der Grond1, Ahmet Ekin2, Adriaan van Es, Mark van Buchem, Rene Engbers2, Arianne van Muiswinkel3, Radu Jasinschi2

1LUMC, Leiden,  Netherlands; 2Philips Research; 3Philips Medical Systems,

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                  2167.    Toward Clinically Practical T2-Mapping for Neurodegenerative Diseases

 

David Henderson1, John Schenck1, 2, Natalie Staples1, Earl Zimmerman2

1GE Global Research, Schenectady, New York, USA; 2Albany Medical College, Albany, New York, USA

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                  2168.    Using Direct Water Saturation for Sensitive Detection of Iron in the Human Brain

 

Seth Aaron Smith1, 2, Jeff W.M. Bulte2, Peter C.M. van Zijl1, 2

1Kennedy Krieger Institute, Baltimore, Maryland, USA; 2Johns Hopkins University, Baltimore, Maryland, USA

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                  2169.    Characterization of the Substantia Nigra in Elderly Subjects by Multi-Modality MRI

 

Yossi Yovel1, Efrat Sasson1, Yaniv Assaf1

1Tel Aviv University, Tel Aviv, Israel

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                  2170.    In Vivo Measurement of Iron Deficiency in Restless Legs Syndrome (RLS) with
                              Voxel-Based R2 Relaxometry

 

Byeong-Yeul Lee1, Elana Farace2, Jeffrey Vesek1, Jianli Wang1, James R. Connor1, Qing Yang1

1Penn State Hershey Medical Center, Hershey, Pennsylvania, USA; 2Penn state Hershey Medical Center, Hershey, Pennsylvania, USA

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                  2171.    The Pattern of Brain Iron Accumulation During Normal Aging

 

Xiaojun Xu1, Minming Zhang1, Qidong Wang1, Fei Sun2

1First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China; 2GE Healthcare China,

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                  2172.    Gender Differences in Brain Iron Level

 

Xiaojun Xu1, Minming Zhang1, Qidong Wang1, Fei Sun2

1First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China; 2GE Healthcare China,

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                  2173.    Estimation of Tissue Iron Contribution to 1H2O R1 Values in Human Brain

 

William D. Rooney1, 2, Glyn Johnson3, Xin Li1, Jeffrey M. Njus1, Thomas M. Barbara1, Kamil Ugurbil4, 5, Charles S. Springer1

1Oregon Health and Science University, Portland, Oregon, USA; 2Brookhaven National Laboratory, Upton, New York, USA; 3New York University, New York, New York; 4University of Minnesota, Minneapolis, Minnesota, USA; 5Max Planck Institute, Tubingen, Germany

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                  2174.    Iron in Basal Ganglia Causes Weak Reproducibility of T2-Weighted Images at 3.0 Tesla

 

Jacobus FA Jansen1, M Eline Kooi1, Alfons G. Kessels1, Klaas Nicolay2, Walter H. Backes1

1Maastricht University Hospital, Maastricht, Netherlands; 2Eindhoven University of Technology, Eindhoven, Netherlands

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                  2175.    Signal and Shape of Subthalamic Nucleus on Susceptibility-Weighted Image (SWI).
                            
-Comparison with STIR Image-

 

Toshiaki Taoka1, Yasushi Kubota2, Hidehiro Hirabayashi1, Hiroyuki Nakagawa1, Masahiko Sakamoto1, Satoru Iwasaki3, Shinji Hirohashi4, Shiro Nakanishi2, Kimihiko Kichikawa1

1Nara Medical University, Kashihara, Nara, Japan; 2Hirai Hospital, Kashihara, Nara, Japan; 3Higashiosaka City General Hospital, Higashiosaka, Osaka, Japan; 4Osaka Gyoumeikan Hospital, Osaka, Japan

 

 

MR Imaging Techniques in MS

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2176.    Persistent Distal White Matter Microstructural Changes Caused by New Lesions at the Earliest
                             Stage of Multiple Sclerosis

 

SungWon Chung1, 2, Daniel Pelletier2, Darin T. Okuda2, Roland G. Henry1, 2

1University of California San Francisco & Berkeley, San Francisco, California, USA; 2University of California San Francisco, San Francisco, California, USA

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                  2177.    Tract-Based Spatial Statistics: Application to the Study of Multiple Sclerosis

 

Caterina Mainero1, David H. Salat1, Francesca Caramia2, Luca Prosperini2, Carlo Pozzilli2, Bruce R. Rosen1

1MGH, Charlestown, Massachusetts, USA; 2University of Rome "La Sapienza", Rome, Italy

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                  2178.    Increased Fractional Anisotropy in Cortical Lesions in Multiple Sclerosis

 

Aziz Hatim Poonawalla1, Rakesh K. Gupta2, Khader M. Hasan1, Chul W. Ahn1, Flavia Nelson1, Jerry Wolinsky1, Ponnada A. Narayana1

1The University of Texas Medical School at Houston, Houston, Texas, USA; 2King George’s Medical University, Lucknow, India

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                  2179.    A Spatial Normalized Study of Diffusion Tensor Imaging in Clinically Isolated Syndrome
                             and Multiple Sclerosis Patients

 

Yasheng Chen1, Valerie Jewells1, Christopher Sayed1, Silva Markovic-Plese1, Hongyu An1, Elizabeth Bullitt1, Weili Lin1

1The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

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                  2180.    Diffusion Tensor Imaging at 7 Tesla: Initial Application to Multiple Sclerosis

 

Meredith Metcalf1, Daniel Pelletier1, Duan Xu1, Darin T. Okuda1, Radhika Srinivasan1, Doug Kelley2, Sarah J. Nelson1, Daniel B. Vigneron1

1University of California, San Francisco, California, USA; 2GE Healthcare, San Francisco, California, USA

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                  2181.    Relation Between Axonal Damage and Inflammation by 1H-MRSI and T2-Weighted Lesion
                              Volume in Early Relapsing Remitting Multiple Sclerosis. The Effect of Subcutaneously
                              Interferon Beta-1a

 

M.Carmen Carmen Martinez-Bisbal1, 2, Ana Maria Pascual3, Beatriz Martinez-Granados1, Caridad Valero3, Francisco Coret4, Isabel Bosca3, Luis Marti-Bonmati2, Bonaventura Casanova3, Bernardo Celda1

1Universitat de Valencia, Burjassot, Valencia, Spain; 2Clinica Quiron, Valencia, Spain; 3Hospital La Fe, Valencia, Spain; 4Hospital Clinico, Valencia, Spain

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                  2182.    Discriminating Multiple-Sclerosis Patient Groups : A Principal-Component Analysis of CSF
                              Metabolite Profiles

 

Norbert W. Lutz1, Angèle Viola1, Irina Malikova1, Sylviane Confort-Gouny1, Jean-Philippe Ranjeva1, Jean Pelletier1, Patrick J. Cozzone1

1Faculté de Médecine de Marseille, Université de la Méditerranée, Marseille, France

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                  2183.    Metabolic Abnormality in Early Multiple Sclerosis Observed by Proton MRS

 

Harald E. Möller1, Timm Wetzel1, Marc Tittgemeyer, 12, Stefanie Hoffmann1, Derek V. M. Ott1, Christoph Preul1, 3, D. Yves von Cramon1, 2

1Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; 2Max Planck Institute for Neurological Research, Cologne, Germany; 3University Hospital Jena, Jena, Germany

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                  2184.    A New Metabolite Characteristic of Inflammatory MS Plaques: The First MRS Assignment

                             of β-Hydroxyisobutyrate in CSF

 

Norbert W. Lutz1, Angèle Viola1, Irina Malikova1, Sylviane Confort-Gouny1, Jean-Philippe Ranjeva1, Jean Pelletier1, Patrick J. Cozzone1

1Faculté de Médecine de Marseille, Université de la Méditerranée, Marseille, France

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                  2185.    WITHDRAWN

 

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                  2186.    Delayed Conscious Access Related to Associative White Matter Fiber Tracts Injury in Patients
                              with Early Relapsing Remitting Multiple Sclerosis

 

Françoise Reuter1, Bertrand Audoin1, Antoine Delcul2, Sylviane Confort-Gouny1, Jean-Philippe Ranjeva1, Patrick J. Cozzone1, Stanislas Dehaene2, Jean Pelletier1

1Faculté de Médecine de Marseille, Université de la Méditerranée, Marseille, France; 2SHFJ, CEA, Orsay, France

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                  2187.    Reproducibility of Quantitative Magnetization Transfer Imaging Parameters

 

Ives R. Levesque1, Sridar Narayanan1, Luciana Torres Ribeiro1, John G. Sled2, Doug L. Arnold1, G. Bruce Pike1

1Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada; 2Hospital for Sick Children, Toronto, Ontario, Canada

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                  2188.    Inhomogeneous Magnetization Transfer Imaging of Myelin Concentration in Multiple Sclerosis

 

David C. Alsop1, 2, Ram Dandamudi, 23, Rohit Bakshi, 23

1Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA; 2Harvard Medical School, Boston, Massachusetts, USA; 3Brigham & Women's Hospital, Boston, Massachusetts, USA

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                  2189.    MTR Abnormalities in Relapse Onset MS Patients 20 Years After the Onset of Disease

 

Leonora K. Fisniku1, Peter A. Brex2, Daniel J. Tozer1, Mara Cercignani1, Daniel R. Altmann1, 3, Katherine Miszkiel4, Klaus Schmierer1, Alan J. Thompson1, David H. Miller1

1Institute of Neurology, London, UK; 2Kings College Hospital, London, UK; 3London School of Hygiene and Tropical Medicine; 4National Hospital for Neurology and Neurosurgey, London, UK

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                  2190.    In Vivo Application of Quantitative Mapping of Myelin Water Fraction Using T2* Decay

 

DOSIK HWANG1, Yiping P. Du1

1University of Colorado Heath Science Center, Denver, Colorado, USA

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                  2191.    Optimization of Multi-Compartment Analysis of T2* Decay in Myelin Water Fraction Mapping with
                              Fixed Brains

 

DOSIK HWANG1, Yiping P. Du1

1University of Colorado Heath Science Center, Denver, Colorado, USA

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                  2192.    Left-Right Differences in 1H2O T1 Values of Multiple Sclerosis Normal Appearing Brain Tissue

 

Jeffrey M. Njus1, Leif Vigeland1, Xin Li1, 2, Charles S. Springer1, 2, Maria Taylor3, Frank W. Telang2, Patricia K. Coyle3, William D. Rooney1, 2

1Oregon Health & Science University, Portland, Oregon, USA; 2Brookhaven National Laboratory, Upton, New York, USA; 3Stony Brook University, Stony Brook, New York, USA

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                  2193.    Quantitative DCE 1H2O R1 Measurements Suggest Increased Fractional Blood Water in
                              MS Normal Appearing Brain Tissue

 

Jeffrey M. Njus1, Leif Vigeland1, Xin Li1, Charles S. Springer1, Maria Taylor2, Frank W. Telang3, Patricia K. Coyle2, William D. Rooney1

1Oregon Health & Science University, Portland, Oregon, USA; 2Stony Brook University, Stony Brook, New York, USA; 3Brookhaven National Laboratory, Upton, New York, USA

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                  2194.    Determining the Age of Multiple Sclerosis Lesions Using Myelin Water Imaging

 

Irene Margaret Vavasour1, Cornelia Laule1, David KB Li1, Anthony L. Traboulsee1, Alex L. MacKay1

1University of British Columbia, Vancouver, BC, Canada

 

 

MS and White Matter Diseases

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2195.    Selective Involvement of the Amygdala in Systemic Lupus Erythematosus

 

Bart Emmer1, Jeroen van der Grond1, Gerda Steup1, Tom Huizinga1, Mark van Buchem1

1Leiden University Medical Centre, Leiden, Netherlands

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                  2196.    MS Repair Potential and Disease Progression from Short-Term T2 Change

 

Dominik S. Meier1, Howard L. Weiner1, Charles R.G. Guttmann1

1Brigham & Women's Hospital, Boston, Massachusetts, USA

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                  2197.    Deep Gray Matter ‘Black T2’ Correlates with Disability in the Minocycline Treated Multiple

                             Sclerosis Patients

 

Yunyan Zhang1, Luanne M. Metz1, V Wee Yong1, J Ross Mitchell1

1University of Calgary, Calgary, AB, Canada

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                  2198.    Development of Central Atrophy May Lead to Underestimation of Lesion Accrual in

                              Patients with Multiple Sclerosis

 

Michael G. Dwyer1, Ondrej Dolezal2, Sara Hussein1, Dana Horakova2, Eva Havrdova2, Jennifer L. Cox1, Robert Zivadinov1

1Buffalo Neuroimaging Analysis Center, Buffalo, New York, USA; 2Charles University, Prague, Czech Republic

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                  2199.    Pathophysiologically Relevant Perivascular Processes in Multiple Sclerosis –

                              Can We Detect Them In Vivo by MRI?

 

Jens Thomas Wuerfel1, Mareile Haertle1, Friedemann Paul1, Helmar Waiczies1, Frauke Zipp1

1Charite University Medicine Berlin, Berlin, Germany

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                  2200.    Detection of Hippocampal Lesions in Multiple Sclerosis with 3D-DIR

 

Stefan Dirk Roosendaal1, Bastiaan Moraal1, Hugo Vrenken1, Petra J.W. Pouwels1, Jonas A. Castelijns1, Frederik Barkhof1, Jeroen J. G. Geurts1

1VU University Medical center, Amsterdam, Netherlands

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                  2201.    Quantitative Analysis of MR-Defined White Matter Hyperintensities in Late-Life Depression.

 

KiSueng Choi1, Paul E. Holtzheimer III, Scott Peltier1, William McDonald, Helen S. Mayberg, Xiaoping Hu1

1Georgia Tech and Emory University, Atlanta, Georgia, USA

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                  2202.    Determinants of Disability in Multiple Sclerosis: A Cross-Sectional, Multiparametric,

                             Quantitative Mr-Based Study of Disease Phenotypes

 

Annalisa Pulizzi1, Marco Rovaris1, Elda Judica1, Maria Pia Sormani1, 2, Vittorio Martinelli1, Andrea Falini1, Giancarlo Comi1, Massimo Filippi1

1Scientific Institute and University Hospital San Raffaele, Milan, Italy; 2University of Genoa, Genoa, Italy

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                  2203.    Optimisation of 3D Inversion Recovery Fast Spin Echo for Lesion Detection in Multiple Sclerosis Brain

 

Klaus Schmierer1, Simon J. Meara2, David H. Miller1, Gareth J. Barker3, Mara Cercignani1

1Institute of Neurology, UCL, London, UK; 2University of Manchester, Manchester, UK; 3Institute of Psychiatry, KCL, London, UK

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                  2204.    Gradient Echo Plural Contrast Imaging for Evaluating Multiple Sclerosis

 

Adil Bashir1, Anne H. Cross1, Dmitriy A. Yablonskiy1

1Washington University in St. Louis, St. Louis, Missouri, USA

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                  2205.    USPIO-Enhanced Cellular Imaging in MS

 

Machteld M. Vellinga1, Jeroen J. Geurts1, Susanne M. van der Pol2, Christiane Pering3, Chris H. Polman1, Helga E. de Vries2, Frederik Barkhof1

1MS Center Amsterdam, VU University Medical Center, Amsterdam, Netherlands; 2MS Center Amsterdam, VU University Medical Center, Amsterdam, Netherlands; 3Schering AG, Berlin, Germany

 

 

Psychiatric Imaging

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2206.    A Learning by Example Approach for MRI Analysis of Human Brain in the Context of Mental Health

 

Paolo Brambilla1, Loris Bazzani2, A Tosato2, Vittorio Murino2, Gianluca Rambaldelli2, Cinzia Perlini2, Manfredo Atzori2, Michele Tansella2, Umberto Castellani2

1University of Udine, Udine, Italy; 2University of Verona, Verona, Italy

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                  2207.    Investigating the Structural Integrity of Brain Tissue in Intermittent Explosive Disorder:

                              A Turboprop-DTI and Voxel-Based Morphometry Study

 

Huiling Peng1, Konstantinos Arfanakis1, K Luan Phan2, Emil L. Coccaro2

1Illinois Institute of Technology, Chicago, Illinois, USA; 2University of Chicago, Chicago, Illinois, USA

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                  2208.    White Matter Impairments as an Endophenotype of Bipolar Disorder –

                              A Diffusion Imaging Study of Patients with Bipolar 1 Disorder and Their Unaffected Relatives

 

Christopher Andrew Chaddock1, Nicolette Marshall1, Katja Schulze1, Xavier Chitnis1, Robin Murray1, Colm McDonald2, Gareth Barker1

1Institute of Psychiatry, London, UK; 2National University of Ireland, Galway, Ireland

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                  2209.    Cortical Expression of Cognitive Control in the Bipolar Disorder Revealed by fMRI

 

Wen-Jui Kuo1, Tzu-Chen Yeh2, Jen-Chuen Hsieh2, Tung-Ping Su2

1National Yang-Ming University, Taipei, Taiwan; 2Taipei Veterans General Hospital, Taipei, Taiwan

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                  2210.    Alterations of Phosmomono- and Phosphodiesters in the Brain of Patients with Major

                              Depression Detected with 3D 31P RINEPT

 

Gabriele Ende1, Tim Wokrina1, Helga Welzel1, Sigi Walter1, Traute Demirakca1, Christine Kief1, Fritz A. Henn2, Alexander Sartorius1

1Central Institute of Mental Health, Mannheim, Germany; 2Brookhaven National Laboratory, Upton, New York, USA

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                  2211.    Event Related fMRI of Successfully Implicitly Encoded Negative and Neutral Words in

                              Major Depressive Disorder.  Preliminary Results from the NESDA Neuroimaging-Study

 

Marie-Jose van Tol1, Marscha Mansvelt1, N.J.A. van der Wee1, D.J. Veltman2, M.M.A. Nielen2, F.G. Zitman1, A. Aleman3, R. Demenescu3, R.J. Renken3, M.A. van Buchem4

1LUMC, Leiden, Netherlands; 2VUmc, Netherlands; 3UMCG, Netherlands; 4LUMC, Netherlands

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                  2212.    Working Memory in Major Depression – An fMRI-Study at 3 T

 

Harald Kugel1, Sonja Schöning1, Katarina Lipina1, Almut Engelien1, Andreas Behnken1, Sebastian Schäfer1, Hagen Schiffbauer1, Irina Brote1, Bernhard Baune1, Volker Arolt1, Walter Heindel1, Carsten Konrad1

1University of Muenster, Muenster, NRW, Germany

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                  2213.    MRI Study of Cerebral Asymmetry in Patients with First-Episode Treatment Naive Schizophrenia

 

Ling Zou1, Luo Ouyang2, Xiao-Qi Huang1, Wei Deng1, Qin Chen1, Yi Wei1, Su Lui1, Hua-Fu Chen2, Tao Li1, Qi-Yong Gong1

1Huaxi Hospital, Sichuan University, Chengdu, People’s Republic of China; 2School of Science and Technology,University of Electronic Science and Technology of China, People’s Republic of China

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                  2214.    Single-Voxel Proton MRS at 1.5 Tesla Significantly Correlates with Hypofrontality in Schizophrenia

 

Jozef Dragašek1, Michal Bittšanský1, Peter Jankoviè1, Milena Drímalová1, Dušan Dobrota1

1Martin Faculty Hospital and Jessenius Medical Faculty, Comenius University, Martin, Slovakia

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                  2215.    Schizophrenia Patients Showed Impaired Hippocampal and Prefrontal Responses During

                              Associative Learning: fMRI Evidence of Hypoactivation and Dysplasticity

 

Vaibhav A. Diwadkar1, 2, Saugata Chakraborty1, Eric Murphy1, Mark D. Benton3, Matcheri S. Keshavan1, 2

1Wayne State University SOM, Detroit, Michigan, USA; 2University of Pittsburgh SOM, Pittsburgh, Pennsylvania, USA; 3Northwestern University, Evanston, Illinois, USA

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                  2216.    Comparison of In Vivo MRI Methods for Examining White Matter Abnormalities in Schizophrenia

 

Bryon Alan Mueller1, Jeffrey R. Wozniak1, Ryan L. Muetzel1, Kelvin O. Lim1

1University of Minnesota, Minneapolis, Minnesota, USA

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                  2217.    The Integrity of Corpus Callosum and Cingulum in Schizophrenia Assessed by Diffusion

                              Tensor Tractography

 

CHIH-JUI RAY CHEN1, HSIAO-LAN WANG1, SHI-KAI LIU2, Van J. WEDEEN3, TIMOTHY G. REESE3, WEN-YIH ISAAC TSENG1, 4

1Center for Optoelectronic Biomedicine, National Taiwan University College of Medicine, Taipei, Taiwan; 2Psychiatry Department, Far Eastern Memorial Hospital, Taipei, Taiwan; 3MGH Martinos Center for Biomedical Imaging, Harvard Medical School, Massachusetts, USA; 4Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan

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                  2218.    Amygdala Anisotropy Correlates with Aggression and Impulsivity

 

Jennifer Lynne Larsen1, 2, Ying Wu1, 2, Rene Ochs1, 2, Carly Demopoulos1, 2, Robert R. Edelman1, 2, Ann B. Ragin1, 2

1Northwestern University, Chicago, Illinois, USA; 2Evanston Northwestern Healthcare, Evanston, Illinois, USA

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                  2219.    Functional MRI Study of Negative Priming Implications for Frontal Disinhibition

 

Ngoc Jade Thai1, Tim L. Hodgson2, Pilar Andres3, Chiara Guerrini4

1Aston University, Birmingham, UK; 2Exeter University, Exeter, UK; 3Plymouth University, Plymouth, UK; 4Hull University, Hull, UK

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                  2220.    Metabolic Alteration of the Dorsolateral Prefrontal Cortex in Depressed Sprague-Dawley Rats by
                              In Vivo
Proton MR Spectroscopy

 

Sung-Tak Hong1, Chi-Bong Choi2, Cheong-Soo Park3, Kwan-Soo Hong3, Bo-Young Choe2

1The Catholic University of Korea, Seoul, Seoul, Seocho-Gu, Republic of Korea; 2The Catholic University of Korea, Seoul, Seocho-Gu; 3Korea Basic Science Institute, Choong-Buk

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                  2221.    Amplitude of Low Frequency Fluctuation in Treatment Naive Schizophrenia Revealed by

                              Resting-State Functional MRI

 

Hong Yang1, Wei Deng2, Tao Li2, Qi Hong Zou3, Xiang Ping Zhou, Yu Feng Zang1, 3, Qi Yong Gong1

1Huaxi MR Research Center (HMRRC),Department of Radiology, West China Hospital of Sichuan University, Chengdu, Sichuan, People’s Republic of China; 2Department of Clinical Psychiatry, West China Hospital of Sichuan University, Chengdu, Sichuan, People’s Republic of China; 3State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, People’s Republic of China

 

 

Epilepsy Imaging and Spectroscopy

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2222.    Metabolic Networks in Temporal Lobe Epilepsy

 

Hoby Patrick Hetherington1, Ruben I. Kuzniecky2, Kenneth Vives1, Dennis D. Spencer1, Jullie W. Pan1

1Yale University, New Haven, Connecticut, USA; 2New York University, New York, New York, USA

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                  2223.    Hippocampal EEG Signal Complexity Correlates with NAA/Cr

 

Jullie W. Pan1, Hitten Zaveri1, Dennis D. Spencer1, Hoby P. Hetherington2

1Yale University School of Medicine, New Haven, Connecticut, USA; 2Albert Einstein College of Medicine, Bronx, New York, USA

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                  2224.    Analysis of Multi-Site Structural Neuroimaging Data Using VBM: A Case Study in Childhood
                              Absence Epilepsy

 

Heath Richard James Pardoe1, Gaby S. Pell1, David F. Abbott1, Anne T. Berg2, Graeme D. Jackson1

1Brain Research Institute, Melbourne, Victoria, Australia; 2University of Northern Illinois, DeKalb, Illinois, USA

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                  2225.    Single Subject Voxel-Based Analysis in Mesial Temporal Lobe Epilepsy

 

Heath Richard James Pardoe1, Gaby S. Pell1, Regula S. Briellmann1, Graeme D. Jackson1

1Brain Research Institute, Melbourne, Victoria, Australia

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                  2226.    Early Reductions in Diffusion Anisotropy Are Apparent in Pediatric Epilepsy

 

Elizabeth B. Hutchinson1, Alan B. McMillan1, Kevin Dabbs1, Bruce P. Hermann1, M Elizabeth Meyerand1

1University of Wisconsin, Madison, Wisconsin, USA

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                  2227.    Significance of Interictal Water Diffusion Changes in Frontal Lobe Epilepsy. Correlations with

                              Stereo-Electro-EncephaloGraphy (SEEG)

 

Maxime Guye1, Jean-Philippe Ranjeva1, Fabrice Bartolomei1, Sylviane Confort-Gouny1, Patrick Chauvel1, Patrick J. Cozzone1

1Université de la Méditerranée, Marseille, France

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                  2228.    Highly Localized Alterations of White Matter in Fixation-Off Sensitivity: A Study Using DTI

 

Taryn Aprile1, Andrea Cherubini2, Carlo Di Bonaventura3, Anna Vaudano3, Anna Teresa Giallonardo3, Bruno Maraviglia4, 5, Gisela Elisabeth Hagberg1

1Santa Lucia Foundation, Rome, Italy; 2IRCCS S.Lucia, Rome, Italy; 3'La Sapienza' University, Rome, Italy; 4Enrico Fermi Centre, Rome, Italy; 5University of Rome 'La Sapienza', Rome, Italy

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                  2229.    Neuroabnormality of Thalamus in Secondarily Generalized Seizure: A Diffusion Tensor Study at 3T

 

Su Lui1, Luo Ouyang2, Qin Chen3, Xiao-qi Huang1, Shu-ying Zhang3, Wei Deng3, He-han Tang1, Hua-fu Chen2, Dong Zhou3, Qi-yong Gong1, 4

1West China Hospital of Sichuan University, Chengdu, Sichuan, People’s Republic of China; 2University of Electronic Science and Technology of China, Chengdu, Sichuan, People’s Republic of China; 3West China Hospital of Sichuan University, Sichuan, People’s Republic of China; 4University of Liverpool, Liverpool, UK

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                  2230.    Positive Default-Mode Activation in Epilepsy Using 2dTCA

 

Victoria L. Morgan1, Jerzy P. Szaflarski2, Bassel Abou-Khalil1, John C. Gore1

1Vanderbilt University, Nashville, Tennessee, USA; 2University of Cincinnati, Cincinnati, Ohio, USA

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                  2231.    Soluble Telencephalin is a Marker for Frontotemporal Dysfunction in Epilepsy as Revealed by fMRI

 

Jacobus FA Jansen1, Marielle CG Vlooswijk1, Mark H. de Baets1, Peter Rieckmann2, M Eline Kooi1, Albert P. Aldenkamp3, H.J. Marian Majoie3, Rianne P. Reijs4, Marc CTFM de Krom1, Paul AM Hofman1, Klaas Nicolay5, Walter H. Backes1

1Maastricht University Hospital, Maastricht, Netherlands; 2Julius-Maximilians University Hospital, Würzburg, Germany; 3Epilepsy Centre Kempenhaeghe, Heeze, Netherlands; 4Epilepsy Centre Kempenhaeghe, Heeze, Netherlands; 5Eindhoven University of Technology, Eindhoven, Netherlands

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                  2232.    Secondarily Generalized Seizures Induce a Functional Reorganization of Working Memory,

                              as Demonstrated by fMRI

 

Jacobus FA Jansen1, Marielle CG Vlooswijk1, M Eline Kooi1, Albert P. Aldenkamp2, H.J. Marian Majoie2, Rianne P. Reijs3, Marc CTFM de Krom1, Paul AM Hofman1, Klaas Nicolay4, Walter H. Backes1

1Maastricht University Hospital, Maastricht, Netherlands; 2Epilepsy Centre Kempenhaeghe, Heeze, Netherlands; 3Epilepsy Centre Kempenhaeghe, Heeze, Netherlands; 4Eindhoven University of Technology, Eindhoven, Netherlands

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                  2233.    High-Resolution Imaging of Normal Human Hippocampus at 7 Tesla

 

Brenda F. Cuson-Reader1, Amir M. Abduljalil1, Georgeta Mihai1, Donald W. Chakeres1, Michael V. Knopp1, Petra Schmalbrock1

1The Ohio State University, Columbus, Ohio, USA

 

 

Head, Neck and Brain Tumor

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2234.    Detecting Oligodendroglioma Genotype Non-Invasively Using MR Imaging

 

Robert A. Brown1, Magdalena Zlatescu1, 2, Peter Forsyth1, 2, Ian Parney1, 2, Robert Sevick1, Doug Demetrick1, David Schiff3, Gregory Cairncross1, 2, Ross Mitchell1

1University of Calgary, Calgary, AB, Canada; 2Southern Alberta Cancer Research Institute, Calgary, AB, Canada; 3University of Virginia, Charlottesville, Virginia, USA

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                  2235.    Perfusion Imaging of Brain Tumor Using Pulsed Arterial Spin Labeling: Correlation

                              with Histopathological Blood Vessel Proliferation

 

Tomoyuki Noguchi1, Takashi Yoshiura1, Akio Hiwatashi1, Osamu Togao1, Koji Yamashita1, Sadahisa Shono, Masahiro Mizoguchi, Tomio Sasaki, Satoshi O. Suzuki, Toru Iwaki, Hiroshi Honda1

1Kyushu University, Fukuoka City, Fukuoka PRF, Japan

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                  2236.    Pre- And Postoperative MR Brain Imaging with Automatic Planning and Scanning Software in

                             Tumor Patients: An Intraindividual Comparative Study at 3 Tesla

 

Michael Nelles1, Jürgen Gieseke1, 2, Horst Urbach1, Renate Bloemer1, Hans H. Schild1, Winfried A. Willinek1

1University of Bonn, Bonn, Germany; 2Philips Medical Systems, Best, Netherlands

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                  2237.    Assessment on Clinical Data of Nonlinear Stochastic Deconvolution Versus SVD and

                              Block-Circulant SVD Methods for Quantitative DSC-MRI

 

Francesca Zanderigo1, Alessandra Bertoldo1, Denis Peruzzo1, Gianluigi Pillonetto1, Mirco Cosottini2, Claudio Cobelli1

1University of Padova, Padova, Italy; 2University of Pisa, Pisa, Italy

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                  2238.    Standardization Decreases Interpatient Differences in rCBV Measurements as a Function of

                              Brain Tumor Grade

 

Devyani Bedekar1, Todd Jensen2, M Fishman1, Kevin Kvasnica1, Eric Paulson1, Melissa Wagnar-Schuman1, Doug Prah1, Kathleen Schmainda1

1Medical College of Wisconsin, Milwaukee, Wisconsin, USA; 2GE Healthcare, Waukesha, Wisconsin, USA

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                  2239.    A Multiparameter DSC Study Demonstrates the Best Predictor of Brain Tumor Grade

 

Melissa Lynne Wagner Schuman1, Devyani Bedekar1, Kevin Kvasnica1, Mathew Fishman1, Eric S. Paulson1, Scott D. Rand1, Hendrikus G.J. Krouwer1, Kathleen M. Schmainda1

1Medical College of Wisconsin, Milwaukee, Wisconsin, USA

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                  2240.    Fitting of the Piecewise Linear Function to Signal Intensity Time Curve and Its Application in

                              Improving the Analysis of Concentration Time Curve of Dynamic Contrast Enhanced-MRI Data

 

Anup Singh1, RKS Rathore1, RK Gupta2, Mohammad Haris2, Divya KS Rathore1, Sanjay K. Verma1, Ankur Purwar1, Getaneh Bayu1, Manoj K. Sarma1, Jitesh K. Singh1

1IIT Kanpur, Kanpur, Uttar Pradesh, India; 2SGPGIMS, Lucknow, Uttar Pradesh, India

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                  2241.    Probing Microvascularity and Heterogeneity of Human Glioma Using Improved T1 Weighted

                              Dynamic Contrast Enhanced MRI

 

Pauliah Mohan1, 2, Vipin Saxena2, Mohammad Haris1, Nuzhat Husain3, RKS Rathore4, Rakesh K. Gupta5

1Sanjay Gandhi Post Graduate Insitute of Medical Sciences, Lucknow, Uttar Pradesh, India; 2BBAU Central University, Lucknow, Uttar Pradesh, India; 3King George’s Medical University, Lucnow, Uttar Pradesh, India; 4Indian Institute of Technology, Kanpur, Uttar Pradesh, India; 5Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India

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                  2242.    MR Based Radiation Therapy Treatment Planning on an Avanto/TIM System

 

Kiaran Patrick McGee1, Debora H. Brinkmann1, Kevin Johnson2, John I. Lane1, Robert L. Foote1, David R. DeLone1, Robert J. Witte1

1Mayo Clinic, Rochester, Minnesota, USA; 2Siemens Medical Systems, Malvin, Pennsylvania, USA

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                  2243.    Diffusion-Weighted Imaging and Apparent Diffusion Coefficient Values for Differentiation of Residual

                              or Local Recurrent Tumor from Posttreatment/Postbiopsy Changes in Patients with Primary Head and

                              Neck Squamous Cell Carcinoma

 

Jeong Hyun Lee1, Chang Woo Ryu2, Hyeon-Mi Yoo1, Hae Wook Pyun1, Sang Yoon Kim1, Deok Hee Lee1, Choong Gon Choi1, Sang Joon Kim1

1University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea; 2Kyung Hee University Medical College, East-West Neomedicine Hospital, Seoul, Republic of Korea

 

 

Clinical Brain Spectroscopy

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2244.    Dual Voxel Two-Dimensional MR Spectroscopy of Hepatic Encephalopathy and Correlation

                              with Neuropsychological Abnormalities

 

Michael Albert Thomas1, Virginia Elderkin-Thompson1, Nagarajan Rajakumar1, Sherry Liu1, Gaurav Verma1, Amir Huda2, Steve Han1, Rakesh K. Gupta1

1David Geffen School of Medicine at UCLA, Los Angeles, California, USA; 2California State University-Fresno, Fresno, California, USA

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                  2245.    Citrate in Pediatric CNS Tumors

 

Zachary A. Seymour1, Jonathan L. Finlay1, Ashok Panigrahy1, Marvin D. Nelson1, Stefan Bluml1, 2

1Childrens Hospital Los Angeles, Los Angeles, California, USA; 2Rudi Schulte Research Institute, Santa Barbara, California, USA

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                  2246.    A Multicentre Study of In Vivo 1HMRS of Paediatric Brain Stem Tumours

 

Lisa Maria Harris1, 2, Nigel P. Davies1, 2, Yu Sun1, 2, Kal Natarajan1, 2, Lesley MacPherson2, Spyros Sgouros, 12, Theo Arvanitis1, 2, Darren Hargrave3, 4, Sophie Riches3, 4, Geoffrey Payne3, 4, Martin Leach3, 4, Franklyn Howe5, Paul Morgan6, 7, Dorothee Auer6, 7, Tim Jaspan6, 7, Richard Grundy6, 7, Andrew C. Peet, 12

1University of Birmingham, Birmingham, UK; 2Birmingham Children's Hospital, Birmingham, UK; 3Royal Marsden Hospital, Sutton, UK; 4Institute of Cancer Research, Sutton, UK; 5St Georges Hospital Medical School, London, UK; 6Nottingham University, Nottingham, UK; 7Queen's Medical Centre, Nottingham, UK

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                  2247.    Correlation Between Choline Concentrations and Trace Values in Human Brain Tumors

 

Dita Wagnerova1, Filip Jiru1, Monika Dezortova1, Lydie Vargova2, Eva Sykova2, Milan Hajek1

1Institute for Clinical and Experimental Medicine, Prague, Czech Republic; 2Institute of Experimental Medicine, AS CR, Prague, Czech Republic

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                  2248.    1H MRSI Study of Effects of Cognitive-Behavioral Therapy on Obsessive-Compulsive Disorder

 

Joseph O'Neill1, Eda Gorbis1, 2, Jamie Feusner1, Karron Maidment1, Jenny Yip2, Susanna Chang1, Noriko Salomon3, Sanjaya Saxena4

1UCLA Psychiatry, Los Angeles, California, USA; 2Westwood Institute, Los Angeles, California, USA; 3UCLA Radiological Sciences, Los Angeles, California, USA; 4UCSD Psychiatry, San Diego, California, USA

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                  2249.    Thalamic Involment in Painful and Painless Diabetic Neuropathy on H-MRS

 

Iain D. Wilkinson1, Rajiv A. Gandhi2, Dinesh Selvarajah2, Jefferson L. Marques2, Celia J. Emery2, Paul D. Griffiths1, Solomon Tesfaye2

1University of Sheffield, Sheffield, UK; 2Royal Hallamshire Hospital, Sheffield, UK

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                  2250.    Single Voxel Proton Resonance Spectroscopy as a Method for the Classification of Brain Tumors

                              Using Artificial Neural Networks

 

Karin Liebenrodt1, Martin H J Busch1, Serban Mateiescu1, Hüseyin Sahinbas1, Jürgen Baier1, Peter Püttmann1, Dietrich H W Grönemeyer1

1Grönemeyer institute for microtherapy, Bochum, NRW, Germany

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                  2251.    GABA Changes Acutely in Human Brain After Nicotine Administration

 

Graeme F. Mason1, June Watzl1, Rosane Gomez1, Elizabeth Guidone, Gerard Sanacora, Tony George2, Peter Jatlow, Richard Kibbey, Gerald Shulman, 3, John H. Krystal, Douglas L. Rothman1, Stephanie O'Malley

1Yale University, New Haven, Connecticut, USA; 2University of Toronto, Toronto, Ontario, Canada; 3Howard Hughes Medical Institute,

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                  2252.    1H MRS Detects Bilateral Abnormalities in Hippocampus of Temporal Lobe Epilepsy Patients

 

Jing Qi1, Dehang Wang1, Yonggang Lu1

1The First Affiliated Hospital of Nanjing Medical University, Nanjing, People’s Republic of China

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                  2253.    1H-MR Spectroscopy Utilizing a 1T Open MR System: Expanding Access to the Obese

                              and Claustrophobic Patient Populations

 

Thomas G. Perkins1, Marijn Kruiskamp2, James Murdoch3, David Hitt1, William W. Orrison4

1Philips Medical Systems, Bothell, Washington, USA; 2Philips Medical Systems, Best, Netherlands; 3Philips Medical Systems, Cleveland, Ohio, USA; 4Amigenics & Nevada Imaging Centers, Las Vegas, Nevada, USA

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                  2254.    Quantitative MR Spectroscopy of Diffuse Intrinsic Brain Stem Glioma

 

Ashok Panigrahy1, Marvin D. Nelson1, Jonathan L. Finlay1, Stefan Bluml1, 2

1Childrens Hospital Los Angeles, Los Angeles, California, USA; 2Rudi Schulte Research Institute, Santa Barbara, California, USA

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                  2255.    Combining Voxel-Based Morphometry and 1H Magnetic Resonance Spectroscopy in Myotonic

                              Dystrophy Type 2 and Type 1

 

Kolja Schiltz1, Joern Kaufmann, Heiko G. Niessen1, Stefan Vielhaber2

1University of Magdeburg, Magdeburg, Sachsen-Anhalt, Germany; 2Universitiy of Magdeburg, Magdeburg, Sachsen-Anhalt, Germany

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                  2256.    Differential Effects of Age on Tissue Water-Referenced Proton Metabolites in Basal Ganglia, Pons, and

                              Cerebellum Using an MRS Sequence Optimized for Glutamate Detection

 

Natalie M. Zahr1, Dirk Mayer1, Adolf Pfefferbaum, 12, Edie V. Sullivan1

1Stanford University, Stanford, California, USA; 2SRI, Menlo Park, California, USA

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                  2257.    Frequency-Dependent Changes in Lactate Concentration During Activation of Human Visual Cortex

 

Ai-Ling Lin1, Jean Hardies1, Jia-Hong Gao2, Carrie S. Gregory1, Peter T. Fox1

1University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA; 2University of Chicago, Chicago, Illinois, USA

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                  2258.    Changes in Brain Energy Metabolism After Carotid Artery Stenting by In Vivo 31P NMR Spectroscopy

 

Sanjay Menon1, 2, Ulrich Pilatus1, Joerg Magerkurth1, Joachim Berkefeld1, Richard du Mesnil de Rochement1, F.E. Zanella1, Heinrich Lanfermann1

1University Hospital Frankfurt, Frankfurt, Germany; 2Krankenhaus Nordwest, Frankfurt, Germany

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                  2259.    Quantitative in-Vivo Brain Water Contents Measurements at 3.0T

 

Shannon Heather Kolind1, Burkhard Mädler2, Irene Margaret Vavasour1, Corree Laule1, Eugene Yip1, Alex L. MacKay1

1University of British Columbia, Vancouver, BC, Canada; 2University of British Columbia Hospital, Vancouver, BC, Canada

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                  2260.    Combined Volumetric MRI and MR Spectroscopic Analyses of the Cerebellum in

                              Developmental Dyslexia

 

Suzanna Kim Laycock1, Roderick Iain Nicolson, Lauren I. Wallis, Gail Darwent, Sarah H. Wonders, Angela J. Fawcett, Paul D. Griffiths, Iain D. Wilkinson

1University of Sheffield, Sheffield, South Yorkshire, UK

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                  2261.    Brain MRSI Metabolic Study of Patients with Remethylation Deficiency

 

Abdesslem Khiat1, François-Guillaume Debray2, Marie Lambert2, Yvan Boulanger1

1Centre hospitalier de l’Université de Montréal, Montréal, Québec, Canada; 2Centre hospitalier universitaire Sainte-Justine, Montréal, Québec, Canada

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                  2262.    Cerebrospinal Fluid Lactate in P. Falciparum Malaria: Measurement by Chemical Shift Imaging

                              at 3 Tesla

 

Christina Louise Tosti1, Esben Thade Petersen2, Jiraporn Laothamatas3, Xavier Golay4, Srirama Venkatraman Swaminathan5, Marc Van Cauteren6, James Murdoch5, Varinee Lekprasert3, Noppadon Tangpukdee3, Srivicha Krudsood3, Wattana Leowattana3, Polrat Wilairatana3, Robert L. DeLaPaz1, Truman R. Brown1, S. Looareesuwan3, Gary M. Brittenham1

1Columbia University, New York, New York, USA; 2National Neuroscience Institute, Singapore, Singapore; 3Mahidol University, Bangkok, Thailand; 4Singapore Bioimaging Consortium, Singapore, Singapore; 5Philips Medical Systems, Cleveland, Ohio, USA; 6Philips Medical Systems Asia Pacific, Tokyo, Japan

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                  2263.    A Study of Cerebral Energetics and pHi in the Visual Cortex Using 31P MRS During

                             Stimulation of Reduced Blood Oxygen Saturation Levels

 

Rishma Vidyasagar1, Risto Kauppinen2

1University of Birmingham, Birmingham, UK; 2University of Birmingham, Birmingham

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                  2264.    MR Spectroscopy of Pituitary Macroadenomas for Preoperative Assessment of

                              Proliferation and Hemorrhage

 

Andreas Stadlbauer1, 2, Christopher Nimsky1, Katja Pinker3, Stephan Gruber3, Erich Salomonowitz2, Michael Buchfelder1, Oliver Ganslandt1

1University of Erlangen-Nuremberg, Erlangen, Germany; 2Landesklinikum St. Poelten, St. Poelten, Austria; 3Medical University of Vienna, Vienna, Austria

 

 

MRI Studies of BBB Permeability

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2265.    Non-Invasive Generation and Monitoring of Ultrasound-Induced Blood-Brain Barrier Opening

                              in the Murine Hippocampus

 

James J. Choi1, Scott A. Small1, Truman R. Brown1, Elisa E. Konofagou1

1Columbia University, New York, New York, USA

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                  2266.    Quantitative Evaluation of BBB Blocking Property of BB1101 Using MRI

 

Saeid Taheri1, Eduardo Candillario-Jalil1, Eduardo Estrada2, Gary Rosenberg2, Rohit Sood1

1University of New Mexico, Albuquerque, New Mexico, USA; 2UNM, New Mexico

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                  2267.    Quantitative Evaluation of the Effect of Propylene Glycol on BBB Permeability

 

Rohit Sood1, Saeid Taheri2, Eduardo Estrada2, Gary Rosenberg2

1University of New Mexico, Albuquerque, New Mexico, USA; 2UNM, New Mexico

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                  2268.    Dynamic Diffusion Process of MRI Contrast Agents Into the Brain Following Blood-Brain

                              Barrier Disruption

 

Marie Blanchette1, Luc Tremblay1, David Fortin1, Martin Lepage1

1Université de Sherbrooke, Sherbrooke, QC, Canada

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                  2269.    Contrast-Enhanced MRI of Blood-Brain Barrier Disruption in CCL2 Transgenic Mice During

                              Pertussis Toxin-Induced Inflammation

 

Angela E. Schellenberg1, Richard Buist1, Henrik Toft-Hansen2, Trevor Owens2, James Peeling1

1University of Manitoba, Winnipeg, Manitoba, Canada; 2University of Southern Denmark, Odense, Denmark

 

 

Stroke:  Clinical Applications

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2270.    Verification of CSF-Based HARM in Acute Stroke Patients with Early Blood-Brain Barrier Disruption

 

Erica C. Henning1, Lawrence L. Latour1, Steven Warach1

1National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA

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                  2271.    Anterograde and Retrograde Degeneration of White Matter Tracts Following Stroke

 

Zohar Ben-Moshe1, Michal Kafri1, Natan Borenstein2, Irena Bova2, Yaniv Assaf1

1Tel Aviv University, Tel Aviv, Israel; 2Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

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                  2272.    Distribution and Progression of Cerebral White Matter Hyper-Intensities Per Flow Territories in a

                              Large Population of Elderly Subjects

 

Enrico Arkink1, Nicole Schmidtz1, Roald van der Landen1, Mark A. van Buchem1, J H. Reiber1, Faiza Admiraal-Behloul1

1Leiden University Medical Center, Leiden, Netherlands

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                  2273.    Application of Geometrical Diffusion Tensor Imaging on Acute Ischemic Cerebral Infarction

 

Chun-Jung Juan1, 2, Yi-Jui Liu3, Ming-Chung Chou1, 2, Chao-Ying Wang1, 2, Hua-San Liu1, 2, Te-Cheng Lai3, Tzung-Tzuo Tsai3, Teng-Yi Huang4, Hsiao-Wen Chung1, 2, Cheng-Yu Chen2

1National Taiwan University, Taipei, Taiwan; 2Tri-Service General Hospital, Taipei, Taiwan; 3Feng Chia University, Taichung, Taiwan; 4National Taiwan University of Science and Technology, Taipei, Taiwan

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                  2274.    Reliability of Mismatch Measurement Methods

 

Marie Luby1, Steven Warach1

1National Institutes of Health, Bethesda, Maryland, USA

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                  2275.    Information Extraction from Ischemic Stroke MR Images Using Independent Component

                              Analysis Technique

 

Siamak Pourabdollah-Nejad1, 2, Hassan Bagher-Ebadian1, Quan Jiang1, 3, Douglas C. Noll2, Daniel C. Alexander4, James R. Ewing1, 3, Kourosh Jafari-Khouzani1, Michael Chopp1, 3

1Henry Ford Health Sciences Center, Detroit, Michigan, USA; 2University of Michigan, Ann Arbor, Michigan, USA; 3Oakland University, Rochester, Michigan, USA; 4University College, London, UK

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                  2276.    Using Principal Component Analysis and Generalized Linear Models to Predict Final Outcome in

                              Acute Stroke

 

Kristjana Ýr Jónsdóttir1, Leif Østergaard2, Kim Mouridsen2

1Aarhus University Hospital, Århus, Denmark; 2Aarhus University Hospital, Århus, Denmark

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                  2277.    Applying Data Mining for the Characterization of Acute Stroke

 

Mathijs Visser1, 2, Ronald Holthuizen1, Frank Hoogenraad1, Arjan W. Simonetti1, Arianne v. Muiswinkel1, Lawrence L. Latour3, Calina Ciuhu4

1Philips Medical Systems, Best, Netherlands; 2Eindhoven University of Technology (TU/e), Eindhoven, Netherlands; 3National Institute of Neurological Disorders and Stroke (NINDS), Washington DC, USA; 4Philips Research, Eindhoven, Netherlands

 

 

Imaging Carotid Disease

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2278.    Time Resolved TWIST MR Angiography of the Head and Neck:

 

Roya S. Saleh1, 2, Stefan G. Ruehm2, John Paul Finn2, Gerhard Laub3

1UCLA, Los Angeles, California, USA; 2University of California Los Angeles, Los Angeles, California, USA; 3Siemens,

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                  2279.    Analysis of Wall Shear Stress of Carotid Bifurcation Using Time-Resolved Three-Dimensional

                              Phase-Contrast MR Imaging

 

Shuhei Yamashita1, Haruo Isoda1, Hiroyasu Takeda1, Yasuhide Okura2, Taro Seo2, Takashi Kosugi2, Hatsuko Nasu1, Shoichi Inagawa1, Yasuo Takehara1, Masaya Hirano3, Atsushi Nozaki3, Kiyoshi Nagasawa3, Marcus T. Alley4, Roland Bammer4, Hiroki Namba1, Harumi Sakahara1

1Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan; 2Renaissance of Technology Corporation, Hamamatsu, Shizuoka, Japan; 3GE Yokogawa Medical Systems, Hino, Tokyo, Japan; 4Stanford University School of Medicine, Stanford, California, USA

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                  2280.    Assessment of Cerebral Metabolic Change in Patients Undergoing Carotid Endarterectomy
                              Using Magnetic Resonance Spectroscopy

 

Takashi Inoue1, Kuniaki Ogasawara1, Masakazu Kobayashi1, Hideaki Nishimoto1, Ryonoshin Hirooka1, Yoshiyuki Kanbara1, Yutaka Matsumura1, Shunrou Fujiwara2, Akira Ogawa1

1Iwate Medical University, Morioka, Iwate, Japan; 2Iwate Medical University, Morioka, Iwa, Japan

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                  2281.    Comparison Between 2D and 3D Black Blood Imaging of the Clinically Significant
                              Carotid Atherosclerotic Plaque

 

Niranjan Balu1, Baocheng Chu1, Thomas Hatsukami1, Chun Yuan1, Vasily L. Yarnykh1

1University of Washington, Seattle, Washington, USA

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                  2282.    Longitudinal 2D Stresses in Carotid Plaques Using MRI-Based Fluid Structure Interaction Models

 

Samuel Alberg Kock1, Jens Vinge Nygaard2, Ernst Torben Fründ3, Erling Falk3, William Paaske3, Won Yong Kim3

1Aarhus University Hospital, Aarhus, Denmark; 2Aarhus University, Denmark; 3Aarhus University Hospital, Denmark

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                  2283.    Vascular Space Occupancy (VASO) MRI Demonstrates Changes in Cerebral Blood Volume in Internal

                              Carotid Artery Stenosis Patients After Carotid Revascularization

 

Manus Joseph Donahue1, Peter Jan van Laar2, Peter van Zijl3, 4, Robert Stevens1, Jeroen Hendrikse2

1The Johns Hopkins School of Medicine, Baltimore, Maryland, USA; 2University Medical Center Utrecht, Utrecht, Netherlands; 3The, Baltimore, Maryland, USA; 4Kennedy Krieger Institute, Baltimore, Maryland, USA

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                  2284.    White Matter Hyperintensities and Balance Control in Elderly People with Diabetes and Hypertension

 

Mareile Haertle1, Peng Zhao1, Kun Hu1, Peter Novak2, Sarah LaRose1, David Alsop1, Vera Novak1

1Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA; 2Boston University, Boston, Massachusetts, USA

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                  2285.    The Value of Diffusion and Perfusion MRI of the Brain in Comatose Patients Treated with

                              Mild Hypothermia After Cardiac Arrest

 

Hanna Sofia Järnum1, Linda Knutsson2, Malin Rundgren2, Roger Siemund2, Elisabet Englund2, Hans Friberg2, Elna-Marie Larsson1

1Aalborg Hospital, Aalborg, Denmark; 2Lund University Hospital, Sweden

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                  2286.    Follow-Up After Endovascular Therapy of Cerebral Aneurysms: A Comparative Study of 

                              Angiographic CT Versus Time-Of-Flight MR-Angiography at 1.5 and 3 Tesla

 

Jan-Hendrik Buhk1, Stefanie Leise1, Kai Kallenberg1, Alexander Mohr1, Peter Dechent1, Michael Knauth1

1University of Göttingen, Göttingen, Germany

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                  2287.    Evaluation of Intracranial Aneurysms with 3T TOF MRA: Compared to 64-MDCTA

 

Yoshiyasu Hiratsuka1, Hitoshi Miki1, Keiichi Kikuchi1, Ikuko Kiriyama1, Teruhito Mochizuki1, Shizue Takahashi2, Ichiro Matsubara2, Kazuhiko Sadamoto2

1Ehime University School of Medicine, Toon, Ehime, Japan; 2Washo-kai Sadamoto Hospital, Matsuyama, Ehime, Japan

 

 

Intracranial MRA

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2288.    Simultaneous and Quantitative Investigation of the Cerebral Arterial and Venous Vasomotor
                              Reactivity Using Phase-Contrast Magnetic Resonance Imaging Technique: A Multi-Fractional
                              CO2   Inhalation Approach

 

Yi-Jui Liu1, Chun-Jung Juan2, 3, Te-Cheng Lai1, Tsai-Tzung Tzuo1, Teng-Yi Huang4, Cheng-Wen Ko5, Meng-Hsueh Yu5, Cheng-Yu Chen2

1Feng Chia University, Taichung, Taiwan, Taiwan; 2Tri-Service General Hospital, Taipei, Taiwan, Taiwan; 3National Taiwan University, Taipei, Taiwan, Taiwan; 4National Taiwan University of Science and Technology, Taipei, Taiwan, Taiwan; 5National Sun Yat-sen University, Kaohsiung, Taiwan, Taiwan

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                  2289.    Assessment of TOF- And CE- MRA in the Visualisation of Small Cerebral Vessel-Structures at 3.0 T

 

Ulrike Wiesspeiner1, Rudolf Stollberger1, Klaus Leber1, Franz Ebner1

1Medical University of Graz, Graz, Austria

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                  2290.    To TOF or Not to TOF; Nonenhanced MRA at 7T

 

Stefan Maderwald1, 2, Jens M. Theysohn1, 2, Oliver Kraff, 12, Susanne C. Ladd, 12, Mark E. Ladd, 12, Karsten Wicklow3, Harald H. Quick, 12, Elke R. Gizewski2

1University Duisburg-Essen, Essen, Germany; 2University Hospital Essen, Essen, Germany; 3Siemens Medical Solutions, Erlangen, Germany

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                  2291.    Time-Resolved 3D Quantitative Flow MRI of the Major Intracranial Arteries

 

Roland Bammer1, Tom Hope1, Marcus T. Alley1

1Stanford University, Stanford, California, USA

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                  2292.    Contrast Enhanced MR Angiography in Intracranial Arterial Stenosis Reveals Collateral Circulation
                              and Angiogenesis

 

Zhen Wu1, 2, Jianping Dai, Ewalt Mark Haacke, 13

1McMaster University, Hamilton, Ontario, Canada; 2Beijing Tiantan Hospital, Beijing, People’s Republic of China; 3Wayne State University, Detroit, Michigan, USA

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                  2293.    High Resolution MRA, Imaging M4 and Beyond

 

Samuel Barnes1, 2, E. Mark Haacke1, 2, Zahid Latif2

1Wayne State University, Detroit, Michigan, USA; 2The MRI Institute for Biomedical Research, Detroit, Michigan, USA

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                  2294.    Time Resolved MRA of Intracranial AVM Patients at 3.0 Tesla: Assessment of Circulation and
                              Transit Times

 

Roya Saleh1, Pablo Villabelanca1, Derek Lohan2, Andik Thomasian2, John Paul Finn1

1University of California Los Angeles, Los Angeles, California, USA; 2University of California Los Angeles, California

 

 

MR Venography

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2295.    The Clinical Value of Veno-BOLD on Vascular Malformations at 3.0T

 

Saying Li1, Rui Wang1, Min Chen1

1Beijing Hospital, Beijing, People’s Republic of China

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                  2296.    Six-Fold 2D-SENSE Accelerated Intracranial Contrast-Enhanced MR Venography -
                              A Comparison Between 1.5T and 3T

 

Houchun Harry Hu1, Clifton R. Haider2, John Huston III2, Norbert G. Campeau2, Stephen J. Riederer2

1University of Southern California, Los Angeles, California, USA; 2Mayo Clinic College of Medicine, Rochester, Minnesota, USA

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                  2297.    Use of 4D-TRAK for Contrast-Enhanced Dynamic MR Venography of the Head

 

Marko K. Ivancevic1, Hemant Parmar2, Suresh Mukherji2, Nancy Dudek2, Romhild Hoogeveen3, Thomas L. Chenevert2

1Philips Medical Systems, Cleveland, Ohio, USA; 2University of Michigan Health System, Ann Arbor, Michigan, USA; 3Philips Medical Systems, Best, Netherlands

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                  2298.    Optimization and Application of Simultaneous Triple Contrast, T1, Arterial TOF and BOLD
                              Venography at 7T

 

Petra Schmalbrock1, Johannes T. Heverhagen1, Donald W. Chakeres1, Hee Chun1, Peter A. Wassenaar1, Georgeta Mihai1, Amir M. Abduljalil1, Steffen Sammet1, Regina Maria Koch1, John Duraj2, Michael V. Knopp1

1The Ohio State University, Columbus, Ohio, USA; 2Philips Medical Systems, Cleveland, Ohio, USA

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                  2299.    Clinical Application of Susceptibility Weighted Imaging (SWI) in Cerebrovascular Disease

 

Wenzhen Zhu1

1Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, People’s Republic of China

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                  2300.    Susceptibility Weighted Imaging (SWI) of Cerebral Blood Oxygenation During
                               Voluntary Hyperventilation and Apnea

 

Yulin Ge1, E Mark Haacke2, Robert I. Grossman1

1New York University School of Medicine, New York City, New York, USA; 2Wayne State University, Detroit, Michigan

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                  2301.    Improved Detection and Diagnosis of Sturge-Weber Syndrome Using MR Susceptibility
                              Weighted Imaging (SWI)

 

Yingjian Yu1, Csaba Juhasz2, Zhifeng Kou2, Yang Xuan2, Zahid Latif2, Kohsuke Kudo2, Harry T. Chugani2, Mark E. Haacke1, 2, Jiani Hu2

1MRI Institute of Biomedical Research, Detroit, Michigan, USA; 2Wayne State University, Detroit, Michigan, USA

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                  2302.    Susceptibility Weighted Imaging Reveals Unique Information in Multiple-Sclerosis Lesions Using
                              High-Field MRI

 

E. Mark Haacke1, Malek I. Makki1, Madeswaran Selvan1, Zahid Latif1, James Garbern1, Jiani Hu1, Meng Law2, Yulin Ge2

1Wayne State University, Detroit, Michigan, USA; 2New York University, New York, New York, USA

 

 

Term and Preterm Brain

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2303.    Development of a MRI Phantom to Emulate the Relaxation Times of the Neonatal Brain at 3 Tesla

 

Timothy Neil Orr1, 2, Neil Gelman1, 2, Jeff Winter1, 2, Gordon Campbell, 23, Robert Terry Thompson1, 2

1Lawson Health Research Institute, London, Ontario, Canada; 2University of Western Ontario, London, Ontario, Canada; 3National Research Council Canada, London, Ontario, Canada

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                  2304.    Transport in the Preterm Infant Brain: Quantitative Analysis of the Relative Roles of Pulsatile Flow
                              and Diffusion

 

Gary P. Zientara1, Janet S. Soul2, Katie E. McCann3, Adre du Plessis2, Haim Bassan2, Richard L. Robertson Jr. 2, Stephan E. Maier1, Ferenc A. Jolesz1, Lawrence P. Panych1, Steven A. Ringer1

1Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA; 2Children's Hospital Boston, Boston, Massachusetts, USA; 3Northeastern University, Boston, Massachusetts, USA

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                  2305.    Quantitative Relationships Between Brain-Water T2 and ADC at Term in Infants Born Prematurely

 

Enrico De Vita1, 2, Cornelia Franziska Hagmann2, Alan Bainbridge1, Basil Andrew Kapetanakis2, Rosarie Lombard1, Nicola J. Robertson2, Ernest B. Cady1, 2

1University College London Hospitals NHS Foundation Trust, London, UK; 2University College London, London, UK

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                  2306.    DTI Evidence of Persistence of the Ventricular Zone in Human Preterm Infants

 

Amit Malhotra1, Terrie E. Inder1, Adrian Epstein1, G. Larrry Bretthorst1, Joshua S. Shimony1, Amit Mathur1, Avi Synder1, Jeffrey J. Neil1

1Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA

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                  2307.    Delayed Maturation of the Cortico-Spinal Tract of Premature Newborns: A Preliminary
                             Study with Quantitative DTI-Based Tractography

 

Jessica Dubois1, Francois Lazeyras1, Muriel Perrin2, Yann Cointepas2, Cristina Borradori-Tolsa1, Stephane Sizonenko1, Petra Huppi1

1Geneva University Hospitals, Geneva, Switzerland; 2CEA, Orsay, France

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                  2308.    Longitudinal fMRI and DTI Study of  Brain Development in Preterm Newborns

 

Paola Scifo1, Cristina Baldoli1, Valeria Blasi1, Silvia Pontesilli1, Roberta Scotti1, Giuseppe Scotti1, Ferruccio Fazio1

1San Raffaele Scientific Institute, Milan, Italy

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                  2309.    Probing the Blood/Brain Barrier in Neonates: 1H-MR Spectroscopy Shows Low Protection Against
                              High Phenylalanine

 

Roland Kreis1, Karin Zwygart1, Chris Boesch1, Joachim Pietz2, Jean-Marc Nuoffer3

1University Berne, Berne, Switzerland; 2University Heidelberg, Heidelberg, Germany; 3University Children's Hospital Berne, Berne, Switzerland

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                  2310.    About the Use of Perfusion-Weighted Magnetic Resonance Imaging to Define Patterns of
                              Neonatal Hypoxic-Ischemic Encephalopathy

 

Pia Wintermark1, Nicola J. Robertson2, Adrien C. Moessinger1, Enrico De Vita, François Gudinchet3, Reto Meuli3

1CHUV, Lausanne, Vaud, Switzerland; 2Institute for Women's Health, University College London, London, UK; 3CHUV, Lausanne, Switzerland

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                  2311.    Is the Ventouse Responsible for Subdural and Extra Cranial Neonatal Hemorrhages?

 

Lauren Ingrid Wallis1, Paul David Griffiths1, Michael F. Smith2, Norman P. Davies3, Martyn N. Paley1, Elspeth Helen Whitby1

1The University of  Sheffield, Sheffield, UK; 2Royal Hallamshire Hospital, Sheffield, UK; 3Mayo Clinic, Rochester, Minnesota, USA

 

 

Pediatric Brain

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2312.    Diffusion Tensor Imaging in Mild and Moderate Pediatric Traumatic Brain Injury

 

Jeffrey Wozniak1, Linda Krach2, Erin Ward1, Bryon Mueller1, Ryan Muetzel1, Sarah Schnoebelen3, Nick Davenport1, Kelvin Lim1

1University of Minnesota, Minneapolis, Minnesota, USA; 2Gillette Children's Specialty Healthcare, St. Paul, Minnesota, USA; 3Children's Medical Center, Dallas, Texas, USA

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                  2313.    Acute Effects of Brain Radiation in Children Evaluated by Diffusion Tensor Imaging

 

Firouzeh Tannazi1, Todd McNutt1, Siamak Ardekani2, Larry J. Brant3, David Bonekamp1, Ori Shokek1, Kenneth Cohen1, Moody Wharam1, Susumu Mori1, Alena Horska1

1Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; 2Johns Hopkins University, Baltimore, Maryland, USA; 3NIH/NIA/GRC, Baltimore, Maryland, USA

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                  2314.    Exogenous Perfusion Imaging in Cortical Developmental Malformations

 

Iain D. Wilkinson1, Elisa Widjaja1, Nigel Hoggard1, Paul D. Griffiths1

1University of Sheffield, Sheffield, UK

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                  2315.    Assymmetric Brain Development in Children with Sturge-Weber Syndrome Demonstrated by
                              Volumetric MRI

 

Matthew R. Amans1, 2, Zhifeng Kou2, Christopher Lai2, Otto Muzik2, Jiani Hu2, Harry T. Chugani2, Csaba Juhasz2

1St. Vincent's Catholic Medical Center, New York, New York, USA; 2Wayne State University, Detroit, Michigan, USA

 

 

Pediatric Psychiatric and Metabolic Disorders

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2316.    Frontal Lobe Function: Association Between Neuropsychological Test Scores and N-Acetyl Aspartate

 

Alena Horska1, Mahaveer Degaonkar1, Melissa A. Matson2, Carolyn T. Wells3, E. Mark Mahone3

1Johns Hopkins University, Baltimore, Maryland, USA; 2University of Cincinnati School of Medicine, Ohio, USA; 3Kennedy Krieger Institute, Baltimore, Maryland, USA

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                  2317.    Using Diffusion Tensor Imaging to Assess White Matter Integrity in Subjects with Math Difficulties

 

Craig Lorang1, Lori Arlinghaus2, Nikki Davis2, John Gore2, Adam Anderson2

1Vanderbilt University, Nashville, Tennessee, USA; 2Vanderbilt University, Tennessee

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                  2318.    Structural Abnormalities of Adolescent Males with Attention-Deficit/Hyperactivity Disorder: A DTI Study

 

Kun-Hsien Chou1, Yuan-Hwa Chou2, Fang-Ying Chiu3, Wan-Yuo Gao4, Tung-Ping Su2, Woei-Chyn Chu1, Ching-Po Lin5

1Institute of Biomedical Engineering, National Yang-Ming University, Taipei, Taiwan; 2Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan; 3Institute of Radiological Sciences, National Yang-Ming University, Taipei, Taiwan; 4Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan; 5Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan

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                  2319.    Investigation by Means of Absolute Quantification of Proton MR Spectroscopy in Adolescent

                              with Attention-Deficit/Hyperactive Disorder

 

Shih-Shan Dong1, Shang-Yueh Tsai2, Ping-Chen Yang3, Cheng-Yun Hsu1, Cheng-Wen Ko1, Ming-Ting Wu4, 5

1National Sun Yat-sen University, Kaohsiung, Taiwan; 2National Taiwan University, Taiwan; 3Kaohsiung Medical University, Kaohsiung, Taiwan; 4Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; 5National Yang Ming University, Taipei, Taiwan

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                  2320.    Accelerated Maturation of White Matter in Young Children with Autism: A High B Value DWI Study

 

Dafna Ben Bashat1, Vered Kronfeld-Duenias1, 2, Ditza A. Zachor3, Perla M. Ekstein1, Talma Hendler1, 2, Ricardo Tarrasch2, Ariela Even4, Yonata Levy4, 5, Liat Ben Sira1

1Tel Aviv Sourasky Medical Center, Tel Aviv, Israel; 2Tel Aviv University, Tel Aviv, Israel; 3Assaf Harofe Medical Center, Tel Aviv, Israel; 4The Hebrew University, Jerusalem, Israel; 5Hadassah-Hebrew University, Jerusalem, Israel

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                  2321.    Cerebral Metabolic Deficits in Young Patients with Tourette Syndrome Assessed by Proton MRSI

 

Tim J. DeVito1, Dick J. Drost1, Richard W.J. Neufeld2, Nagalingam Rajakumar2, Peter C. Williamson, 12, Rob Nicolson, 12

1University of Western Ontario, Lawson Health Research Institute, London, Ontario, Canada; 2University of Western Ontario, London, Canada

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                  2322.    Investigating Williams Syndrome with Diffusion Tensor Imaging

 

Lori R. Arlinghaus1, Colin B. Compas1, Elisabeth M. Dykens1, Adam W. Anderson1

1Vanderbilt University, Nashville, Tennessee, USA

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                  2323.    Assessing Disease Severity in Late Infantile Neuronal Ceroid Lipofuscinosis Using Quantitative Magnetic

                              Resonance Diffusion-Weighted Imaging

 

Jonathan P. Dyke1, Henning U. Voss1, Dolan Sondhi1, Neil R. Hackett1, Stefan Worgall1, Linda A. Heier1, Barry E. Kosofsky1, Aziz M. Ulug1, Dikoma C. Shungu1, Xiangling Mao1, Ronald G. Crystal1, Douglas Ballon1

1Weill Medical College of Cornell University, New York, USA

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                  2324.    Diffusion Tensor Imaging in Niemann-Pick C Disease on 3T

 

Christabel EC Lee1, David M. Thomasson1, Forbes D. Porter1, Andrea L. Gropman1, Nicole M. Yanjanin1, Eva H. Baker1

1National Institutes of Health, Bethesda, Maryland, USA

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                  2325.    Regional and Global Apparent Diffusion Coefficient in Inherited Prion Diseases: Correlation

                              with Disease Severity

 

Harpreet Hyare1, Durre Siddique1, Tom Webb1, Steve Wroe1, John Collinge1, John Thornton1, Tarek Yousry1

1Institute of Neurology, London, UK

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                  2326.    The Usefulness of Proton MRS in Monitoring Ketogenic Diet Therapy in Mitochondrial Encephalopathy

 

Seung-Koo Lee1, Jinna Kim1, Eung Yeop Kim1

1Yonsei University College of Medicine, Seoul, Republic of Korea

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                  2327.    An Autopsy Brain of Alexander Disease Studied by Comparison of Histology with High Resolution
                              T2*-Weighted MRI at 7T

 

Matsuda Kant1, Tie-Qiang Li2, E Rushing3, M Quezado1, S Dodd4, H Merkle4, J Duyn4

1NCI, USA; 2NINDS, Bethesda, Maryland, USA; 3Armed Forces Institute of Pathology; 4NINDS, USA

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                  2328.    Leukoencephalopathy with Brain Stem and Spinal Cord Involvement and Elevated White
                              Matter Lactate (LBSL). Serial Proton MRS and DTI of a Child Over a Period of 6 Years

 

Steffi F. Dreha-Kulaczewski1, Peter Huppke1, Knut Brockmann1, Peter Dechent1, Gunther Helms1, Jürgen Finsterbusch2, Jens Frahm3, Jutta Gaertner1

1Georg August University, Goettingen, Germany; 2University Medical Center Hamburg-Eppendorf, Germany; 3Biomedizinische NMR Forschungs GmbH am MPI fuer biophysikalische Chemie, Goettingen, Germany

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                  2329.    Correlation Between Brain Metabolites and Very Long Chain Fatty Acid Levels in Asymptomatic
                              Boys with X-Linked Adrenoleukodystrophy

 

Michael J. Moser1, Gerald V. Raymond2, Hugo W. Moser2, Peter B. Barker1, 2

1Johns Hopkins University Sch of Med, Baltimore, Maryland, USA; 2Kennedy Krieger Insitute, Baltimore, Maryland, USA

 

 

Spine

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2330.    Measurement of T1 and T2 in the Cervical Spinal Cord at 3 Tesla

 

Seth Aaron Smith1, 2, Richard A.E. Edden1, 2, Peter B. Barker1, 2, Peter C.M. van Zijl1, 2

1Kennedy Krieger Institute, Baltimore, Maryland, USA; 2Johns Hopkins University, Baltimore, Maryland, USA

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                  2331.    3D Myelin Water Imaging in the Spinal Cord at 3.0T

 

Erin Leigh MacMillan1, Burkhard Mädler2, Shannon Heather Kolind1, Eugene Yip1, Alex L. MacKay1

1University of British Columbia, Vancouver, BC, Canada; 2University of British Columbia Hospital, Vancouver, BC, Canada

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                  2332.    Quantitative MT (qMT) Characteristics of the Human Spinal Cord In Vivo

 

Seth Aaron Smith1, 2, Peter C.M. van Zijl1, 2, Gerald V. Raymond, 12, Hugo W. Moser, 12, Greg J. Stanisz3, 4

1Kennedy Krieger Institute, Baltimore, Maryland, USA; 2Johns Hopkins University, Baltimore, Maryland, USA; 3Sunnybrokk & Women's College Health Science Center, Toronto, Canada; 4University of Toronto, Toronto, Canada

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                  2333.    Quantitative Cervical Proton Magnetic Resonance Spectroscopy of Relapsing-Remitting
                              Multiple Sclerosis

 

Anna Federica Marliani1, Valeria Clementi2, Luca Albini Riccioli1, Raffaele Agati1, Marco Leonardi1

1Bellaria Hospital, Bologna, Italy, Italy; 2GE Healthcare, Bologna, Italy, Italy

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                  2334.    Quantitative Cervical Proton Magnetic Resonance Spectroscopy of Multiple Sclerosis

 

Anna Federica Marliani1, Valeria Clementi2, Luca Albini Riccioli1, Raffaele Agati1, Marco Leonardi1

1Bellaria Hospital, Bologna, Italy, Italy; 2GE Healthcare, Bologna, Italy, Italy

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                  2335.    A One Year Follow-Up Study of the Spinal Cord with Biplanar MRI in Multiple Sclerosis –
                              Clinical and MR Aspects

 

Katrin Weier1, Yvonne Naegelin1, Alain Thoeni1, Jochen Hirsch1, Ludwig Kappos1, Ernst-Wilhelm Radue1, Achim Gass1

1University Hospital Basel, Basel, Switzerland

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                  2336.    Kinematic MR Imaging Using 3D FIESTA and Diffusion Tensor Imaging on an Open-Type MR Scanner

 

Masaaki Hori1, 2, Keiichi Ishigame2, Hiroshi Kumagai2, Kenji Suzuki3, Kenichi Kanda3, Hitoshi Terada4, Hisamoto Moriguchi1, Morio Shimada1, Eiichi Koda4, Tsutomu Araki2

1Toho University, Ota, Tokyo, Japan; 2University of Yamanashi, Chuo, Yamanashi, Japan; 3GE Healthcare, Japan; 4Toho University, Tokyo, Japan

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                  2337.    The Combined Application of MRI and 3D Contrast Enhanced Time-Resolved MRA in Detecting
                              Spinal Cord Vascular Diseases

 

Wen-zhen Zhu1

1Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei Province, People’s Republic of China

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                  2338.    Clinical Application Study of MR Perfusion Imaging and Diffusion Tensor Imaging in the
                              Tumor Like Lesions of the Cervical Spinal Cord

 

Xiang Liu1, Wei Tian1, Yoshimitsu Ohgiya1, Sven Ekholm1, Per Lennart Westesson1

1University of Rochester Medical Center, Rochester, New York, USA

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                  2339.    Initial Experience with Isotropic 3D-FSE-XETA (eXtended Echo Train Acquisition) Imaging
                              of the Cervical Spine

 

David B. Hackney1, Reed Busse2, Nagamani Peri1, Ken Hwang3, Charles A. McKenzie1

1Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA; 2GE Healthcare, Waukesha, Wisconsin, USA; 3GE Healthcare, Houston, Texas, USA

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                  2340.    Consistent Automated Scan Planning of Spine

 

René Bergmans1, Chiel den Harder1, Arjan Willem Simonetti1, Vladimir Pekar2, Daniel Bystrov2, Rüdiger Grewer2, Arianne M C van Muiswinkel1

1Philips Medical Systems, Best, Netherlands; 2Philips Research Europe, Hamburg, Germany

 

 

Normal Brain Animal MRI

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2341.    Spinal Cord Blood Flow (SCBF) Measurement by Arterial Spin Labeling (ASL)

 

Guillaume Duhamel1, Virginie Callot1, Patrick J. Cozzone1, Frank Kober1

1Faculté de Médecine de Marseille, Université de la Méditerranée, Marseille, France

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                  2342.    Multi-Layers Structure of Mouse Retina Detected Using T2 and ADC In Vivo

 

Qing Wang1, Junjie Chen2, Huiying Zhang3, Bruce A. Berkowitz4, Sheng-Kwei Song2

1Washington University in St.Louis, Sain Louis, Missouri, USA; 2Washington University in St. Louis, Saint Louis, Missouri, USA; 3Washington University, Saint Louis, Missouri, USA; 4Wayne State University School of Medicine, Detroit, Michigan, USA

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                  2343.    Magnetic Resonance Microscopy of Ex Vivo Mouse Brains: Contrast and Structure

 

Shuning Huang1, 2, Christina Liu2, Guangping Dai2, Bruce Rosen1, 2

1MIT, Cambridge, Massachusetts, USA; 2MGH, Charlestown, Massachusetts, USA

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                  2344.    Morphological Difference Between In Vivo and Ex Vivo Adult C57BL/6J Mouse Brain by
                              Magnetic Resonance Microscopy

 

Yu Ma1, Bernd Foester2, Patrick Hof3, Scott Hamilton4, Smith David5, Yu Mei, Helene Benveniste

1Stony Brook University, Stony Brook, New York, USA; 2Phillips Inc., Brazil; 3Mount Sinai Shool of Medicine; 4Stony Brook University, New York; 5Brookhaven National Lab, New York

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                  2345.    High Field Imaging of Non-Human Primates: Anatomical Imaging and Relaxation Rates

 

L Martyn Klassen1, Ravi S. Menon1, 2

1Robarts Research Institute, London, Ontario, Canada; 2University of Western Ontario, London, Ontario, Canada

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                  2346.    The Developing Canine Brain: Characterization by MRS and DTI

 

Norman B. Konyer1, 2, Michael D. Noseworthy1, 3, Christina de Rivera4, Norton W. Milgram4, Howard Dobson2

1St. Joseph's Healthcare, Hamilton, Ontario, Canada; 2University of Guelph, Guelph, Ontario, Canada; 3McMaster University, Hamilton, Ontario, Canada; 4Cancog Technologies, Toronto, Ontario, Canada

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                  2347.    Chromium(VI)-Enhanced MRI of White Matter in Mouse Brain

 

Takashi Watanabe1, Jens Frahm1, Thomas Michaelis1

1Biomedizinische NMR Forschungs GmbH, Göttingen, Germany

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                  2348.    Relaxometry Study of Baboon Fetal Brains at 3T

 

Feng Liu1, 2, Marrianne Garland1, Raymond Stark1, Bradley S. Peterson1, 2, Yunsuo Duan1, 2, Alayar Kangarlu1, 2

1Columbia Universiy, New York, New York, USA; 2New York State Psychiatric Institute, New York, New York, USA

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                  2349.    Correlating In Vivo MRI with 3D Post Mortem Information in Rat Brain

 

Alexandre Guimond1, Albertine Dubois2, Anne-Sophie Hérard2, Philippe Méric3, Brigitte Gillet3, Thierry Delzescaux2

1Siemens Molecular Imaging, Oxford, UK; 2Commissariat à l'Energie Atomique, Orsay, France; 3CNRS-ICSN, Gif-sur-Yvette, France

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                  2350.    Comparison of Spinal Vasculature in Mouse and Rat: Investigations Using Magnetic
                              Resonance Angiography

 

Mehmet Bilgen Bilgen1

1The University of Kansas Medical Center, Kansas City, Kansas, USA

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                  2351.    High Temporal Resolution Measurements of Metabolic Water Production from 17-Oxygen
                              Bolus Gas Delivery in a Large Animal

 

Eric Albert Mellon1, Mallikarjunarao Kasam1, Reddy Shashank Beesam1, Santhosh R. Gaddam1, James E. Baumgardner2, Arijitt Borthakur1, Ravinder Reddy1

1University of Pennsylvania, Philadelphia, Pennsylvania, USA; 2Oscillogy LLC, Folsom, Pennsylvania, USA

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                  2352.    Monitoring Brain Dimpling and Intracortical Micro-Electrode Arrays with High Resolution MRI in Rats

 

Thomas Neuberger1, Kunal Paralikar, Xiaofeng Zhang1, Ryan S. Clement, Andrew Webb1

1Huck Institute Magnetic Resonance Centre, Penn State University, University Park, Pennsylvania, USA

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                  2353.    WITHDRAWN

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                  2354.    Near-Infrared Light Penetration in Rat Brain Modeled Using MRI Structural Information

 

Calvin L. Gerus1, Hamid Dehghani2, Kevin Forrester1, Jeff F. Dunn1

1University of Calgary, Calgary, AB, Canada; 2University of Exeter, Exeter, UK

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                  2355.    In Vivo Imaging of Nicotine-Exposed Adult Male Zebra Finches

 

Susanne L.T. Cappendijk1, John R. James2, Samuel Colles Grant3, 4

1College of Medicine, Tallahassee, Florida, USA; 2Virginia Commonwealth University, Richmond, Virginia, USA; 3The National High Magnetic Field Laboratory, Tallahassee, Florida, USA; 4The Florida State University, Tallahassee, Florida, USA

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                  2356.    Feasibility Study of the Cerebrospinal Fluid Flow Circulation in the Brain of Dogs with
                              H217O Using Magnetic Resonance Imaging

 

Bilgin Keserci1, Akira Nakatani2, Yuji Hashiguchi1, Kumiko Iwai2, Hiroshi Taira3, Akihiko Maeda3, Tsuyoshi Matsuda1, Hasnine Akter Haque1, Kiyoshi Nagasawa1

1GE Healthcare, Tokyo, Japan; 2Nihon Medi-Physics Co. Ltd., Chiba, Japan; 3Taiyo Nippon Sanso Co., Tokyo, Japan

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                  2357.    Simultaneous Measurements of Ascorbic Acid and NAA in the Rat Brain In Vivo Using a Single-Shot,

                              Two-Echo Selective Multiple Quantum Spectroscopy

 

In-Young Choi1, Sang-Pil Lee1

1University of Kansas Medical Center, Kansas City, Kansas, USA

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                  2358.    In Vivo Brain 1H-MRS of Sodium Pentobarbital: A Potential Index Reflecting Anesthesia
                              Depth and States of Brain Energy Metabolism and Activity

 

Fei Du1, Yi Zhang1, Xiao-Hong Zhu1, Wei Chen1

1University of Minnesota, Minneapolis, Minnesota, USA

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                  2359.    High Field (7 T) and Spatial Resolution (0.05 Ml Voxels) 3D MRSI in the Rhesus Macaque Brain

 

Songtao Liu1, Gadi Goelman2, Eva-Maria Ratai3, Margaret Lentz3, Sarah Pilkenton3, Ramon Gilberto Gonzalez3, Oded Gonen1

1New York University School of Medicine, New York, New York, USA; 2Hadassah Hebrew University Medical Center, Jerusalem, Israel; 3Massachusetts General Hospital, Charlestown, Massachusetts, USA

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                  2360.    Characterization of Age Induced Brain Changes Using MRI in Rats

 

Tamar Blumenfeld-Katzir1, Ofer Pasternak, Yaniv Assaf1

1Faculty of Life Sciences,Tel-Aviv University, Tel-Aviv, Israel

 

 

Normal Brain Animal MRS

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2361.    Characterization of Metabolism in Rat Olfactory Bulb by In Vivo 1H and 1H-[13C] NMR

 

Golam M.I. Chowdhury1, Kvein L. Behar1, Douglas L. Rothman1, Robin A. de Graaf1

1Yale University, New Haven, Connecticut, USA

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                  2362.    Regional and Developmental Variation in Vitamin C Concentration in the Rat Brain Quantified

                              In Vivo Using Short Echo-Time 1H MRS

 

Melissa Terpstra1, Raghavendra Rao1, Ivan Tkac1

1University of Minnesota, Minneapolis, Minnesota, USA

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                  2363.    In Vivo 13C MRS Using Very Low RF Power for Proton Decoupling

 

Shizhe Steve Li1, Jehoon Yang1, Jun Shen1

1NIH, Bethesda, Maryland, USA

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                  2364.    In Vivo Metabolite Differences Between the Basal Ganglia and Cerebellum of the Rat Brain

                              Detected with Proton MRS at 3 T

 

Dirk Mayer1, Natalie M. Zahr1, Edith V. Sullivan1, Adolf Pfefferbaum1, 2

1Stanford University, Stanford, California, USA; 2SRI International, Menlo Park, California, USA

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                  2365.    Cerebral Metabolic Effect of Acute Inhibition of Aspartate Aminotransferase Measured by 1H MRS

 

Su Xu1, Wenjun Zhu1, Jun Shen1

1National Institute of Mental Health, Bethesda, Maryland, USA

 

 

MRS/MRI of Animal Trauma Models

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2366.    Differential Cellular Metabolism Following Traumatic Brain Injury

 

Brenda Bartnik Olson1, David Hovda2, Richard Sutton2

1Loma Linda University, Loma Linda, California, USA; 2UCLA Brain Injury Research Center, Los Angeles, California, USA

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                  2367.    Is Glutamate or Glutamine Elevated Following Traumatic Brain Injury?

 

William Miles Brooks1, 2, Gregory Onyszchuk, In-Young Choi, Sang-Pil Lee, Crystal Bethel, Nancy E.J. Berman

1University of Kansas Medical Center, Kansas City, Kansas, USA; 2KUMC, Kansas City, Kansas, USA

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                  2368.    Monitoring Stem Cell Therapies of Spinal Cord Injury Using Quantitative T2 Relaxation

 

Greg Jan Stanisz1, Soheila Karimi-Abdolrezaee2, Nancy Lobaugh1, Wendy Oakden3, Voytek Gretka1, Eftekhar Efetkharpour2, Greg Hawryluk2, Jian Wang2, Michael Fehlings2

1Sunnybrook HSC, Toronto, Ontario, Canada; 2Toronto Western Hospital, Toronto, Ontario, Canada; 3University of Toronto, Toronto, Ontario, Canada

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                  2369.    Cervical Spinal Cord Injury in the Rat: Longitudinal MRI Comparison of Two Injury Severity Levels

 

Georgeta Mihai1, Yvette S. Nout1, C Amy Tovar1, Brandon A. Miller1, Petra Schmalbrock1, Jacqueline C. Bresnahan1, Michael S. Beattie1

1The Ohio State University, Columbus, Ohio, USA

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                  2370.    Quantitative MRI and MRS at Five to Eleven Months After Traumatic Brain Injury in Rat

 

Riikka Johanna Immonen1, Irina Kharatishvili1, Asla Pitkänen1, Juha-Pekka Niskanen1, Olli H.J. Gröhn1

1A. I. Virtanen Institute for Molecular Sciences, University of Kuopio, Kuopio, Finland

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                  2371.    In Vivo Visualization of Spinal Cord Injury in Experimental Mouse Model: A Feasibility

                             Study on a Clinical 3.0 Tesla MR System

 

Ming Yang1, Zhen Guan1, Amir Abduljalil1, Gregory A. Christoforidis1, Phillip G. Popovich1, Jun Zhang1, Michael V. Knopp1

1The Ohio State University, Columbus, Ohio, USA

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                  2372.    A Simple, Robust, and Accurate Contusion Spinal Cord Injury Device for the Mouse

                             Characterized by Diffusion MRI

 

Joong Kim1, Philip Bayly2, Sheng-Kwei Song1

1Washington University School of Medicine, St. Louis, Missouri, USA; 2Washington University, St. Louis, Missouri, USA

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                  2373.    ASL-MRI Assessment of the Effect of Hemorrhagic Shock on Cerebral Blood Flow After

                              Experimental Traumatic Brain Injury in Mice

 

Lesley M. Foley1, A M. Dennis2, T Kevin Hitchens1, J A. Melick2, C Ho1, P M. Kochanek2

1Carnegie Mellon University, Pittsburgh, Pennsylvania, USA; 2University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

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                  2374.    Effect of iNOS on Cerebral Blood Flow After Head Trauma

 

Lesley M. Foley1, T Kevin Hitchens1, P M. Kochanek2, J A. Melick2, C Ho1

1Carnegie Mellon University, Pittsburgh, Pennsylvania, USA; 2University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

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                  2375.    Erythropoietin Protects from Posttraumatic Edema in the Rat Brain: MRI and Gravimetric Studies

 

Hana Lahrech1, 2, Yohan van de Looij1, 2, Olivier Verdonck1, 2, Gilles Francony1, 2, Olivier Carle1, 2, Régine Farion1, 2, Chantal Rémy1, 2, Christoph Segebarth1, 2, Jean-François Payen1, 2

1INSERM U594, Grenoble, France; 2Univ Joseph Fourier, Grenoble, France

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                  2376.    Longitudinal MRI of Spinal Cord Injury in Mouse: Changes in Signal Patterns Associated

                              with the Inflammatory Response

 

Mehmet Bilgen Bilgen1

1The University of Kansas Medical Center, Kansas City, Kansas, USA

 

 

Stroke Animal Models

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2377.    QMT Is Specifically Sensitive to Myelin and Not Axonal Injury in Optic Nerve from Mice 

                              Undergoing Transient Retinal Ischemia

 

Xiawei Ou1, Shu-Wei Sun2, Daniel Frank Gochberg1, Sheng-Kwei Song2

1Vanderbilt University, Nashville, Tennessee, USA; 2Washington University School of Medicine, St. Louis, Missouri, USA

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                  2378.    Neurochemical Modulation in a Rat Model of Birth Asphyxia Detected by In Vivo Proton MRS

 

Todd Atwood1, April Ronca1, Gale Kleven1, Jian-Ming Zhu1

1Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA

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                  2379.    Investigation of Metabolite Changes in Neonatal Rat Brain After Cerebral Hypoxia-Ischemia

                              Using 1H-Spectroscopy at 9.4T

 

Nathalie Just1, 2, Nicolas Kunz2, Ingrid Kohler2, Petra S. Huppi3, Stephane V. Sizonenko3, Rolf Gruetter1, 2

1UNIL, Lausanne, Switzerland; 2CIBM/LIFMET, Lausanne, Switzerland; 3UNIGE, Geneva, Switzerland

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                  2380.    Intracellular pH After Perinatal Cerebral Hypoxia-Ischaemia Estimated from Nucleotide Triphosphate, 

                              Phosphoethanolamine, and Inorganic Phosphate Chemical Shifts

 

Ernest B. Cady1, Alan Bainbridge2, Ann Lorek3, Juliet Penrice3, Osuke Iwata3, John Wyatt3, Nicola J. Robertson3

1University College London Hospitals NHS Foundation Trust, London, UK; 2University London Hospitals NHS Foundation Trust, London, UK; 3University College London, London, UK

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                  2381.    MRI Assessment of Regional Cerebral Blood Flow After Asphyxial Cardiac Arrest in Immature

                              Rats: A Preliminary Report

 

Lesley M. Foley1, M D. Manole2, T Kevin Hitchens1, H L. Alexander2, C Ho1, P M. Kochanek2, R S. Clark2

1Carnegie Mellon University, Pittsburgh, Pennsylvania, USA; 2University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

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                  2382.    Diffusion and Perfusion Changes During Long-Term Recovery After Prolonged Hypoxia

 

Nicole R. Brandon1, 2, Marc Uy1, 2, Renee Dallasen1, 2, Aaron Hirko1, Sachiko Jomura1, Yan Xu*1

1University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; 2 (equal contribution),

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                  2383.    Iron-Labeled Neural Stem Cell Homing After Neonatal Hypoxia-Ischemia

 

Andre Obenaus1, Stephan Ashwal1, Murat Digicaylioglu2, Beatrice Tone1, Amber Wang1, Hui Rou Tian1, Evan Snyder3

1Loma Linda University, Loma Linda, California, USA; 2University of California, San Diego, San Diego, California, USA; 3Burnham Institute, La Jolla, California, USA

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                  2384.    Temporal and Regional Evolution of Aquaporin 4 Expression and Magnetic Resonance

                              Imaging in a Rat Pup Model of Neonatal Stroke

 

Andre Obenaus1, Stephan Ashwal1, Beatrice Tone1, Amber Wang1, L Regli2, Hui Rou Tian1, Jérôme Badaut2

1Loma Linda University, Loma Linda, California, USA; 2Centre hospitalier universitaire vaudois, Lausanne, Switzerland

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                  2385.    Quantitative Evaluation of Blood-Brain Barrier (BBB) Permeability Using Patlak Plots Methodology

                              in a Model of Transient Focal Ischemia in Rats

 

Usama Abo Ramadan1, Aysan Durukan1, Miia Pitkonen1, Lauri Soinne1, Ivan Marinkovic1, Ertugrul Tatlisumak1, Eric pedrono1, Daniel Strbian1, Turgut Tatlisumak1

1Helsinki University Central Hospital, Helsinki, Finland

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                  2386.    Effect of Hypothyroidism in Metabolic Profile of Rats After Cerebral Ischemia/reperfusion:

                              A 1H NMR Study

 

Leena Rastogi1, Syed Naved Akhtar2, Madan M. Godbole3

1Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India; 2Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India; 3Sanjay Gandhi Post Graduate Institute, Lucknow, Uttar Pradesh, India

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                  2387.    Combining 31P-MRS with Near-Infrared Spectroscopy to Measure the Concurrent Changes in
                              Energy Metabolites and Cerebral Oxygen Consumption Following Hypoxia Ischemia

 

Jeff David Winter1, Kenneth M. Tichauer1, 2, Neil Gelman1, 2, R Terry Thompson1, 2, Ting Yim Lee1, 2, Keith St. Lawrence1, 2

1Lawson Health Research Institute, London, Ontario, Canada; 2University of Western Ontario, London, Ontario, Canada

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                  2388.    Temporal Profiles of the Infarct Frequency in Acute Stroke

 

Qiang Shen1, Hanh Nguyen1, Timothy Q. Duong1

1Emory Unviersity, Atlanta, Georgia, USA

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                  2389.    Direct Comparison of T2 and T2ρ Image Contrast in a Rat Model of Acute Cerebral Ischemia

 

Simona Nikolova1, Robert Bartha1, Miranda Bellyou1

1Robarts Research Institute, London, Ontario, Canada

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                  2390.    Quantification of Multicomponent T2 in Brain After Reversible Ischemia

 

Jeff F. Dunn1, Debora A. Kelly1, Cheryl McCreary1, Thorarin A. Bjarnason1, Zonghang Zhao1, Ross Mitchell1

1University of Calgary, Calgary, AB, Canada

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                  2391.    Temporal Assessment of Rat Brain Vasculature After Transient Focal Cerebral Ischemia

 

Chien-Yuan Lin1, 2, Jyh-Horng Chen1, Ming-Huang Lin2, Wai-Mui Cheung2, Teng-Nan Lin2, Chen Chang2

1Interdisciplinary MRI/MRS Lab, Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan; 2Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

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                  2392.    How Long Does It Take Before ADC Reduction Becomes Irreversible?

 

Qiang Shen1, Erica Fletcher1, Timothy Q. Duong1

1Emory Unviersity, Atlanta, Georgia, USA

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                  2393.    Simultaneous and Ultrafast Monitoring of CMRO2, CBF and pO2 Changes in Response to
                              Acute Global Ischemia in Rat Brain

 

Xiao-Hong Zhu1, Yi Zhang1, Wei Chen1

1CMRR, Department of Radiology, University of Minnesota Medical School, Minneapolis, Minnesota, USA

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                  2394.    Reperfusion-Based Hemorrhagic Transformation in Spontaneously Hypertensive Rats:
                              A Model for Translational Research

 

Erica C. Henning1, Lawrence L. Latour1, John M. Hallenbeck1, Steven Warach1

1National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA

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                  2395.    In Vivo Assessment of Optic Nerve Degeneration in Glaucoma Rat Model Using Diffusion Tensor Imaging

 

Edward Sai Kam Hui1, Sheryle Q. Fu1, Kevin Chuen Wing Chan1, Kwok Fai So1, Ed Xuekui Wu1

1The University of Hong Kong, Pokfulam, Hong Kong

 

 

Neuro MRI of Genetic Animal Models

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2396.    Assessment of Neuronal Marker and Brain Iron in Aphakia Mice Model for Parkinson’s Disease
                              Using Novel MRI Contrasts

 

Shalom Michaeli1, Terry Burns, Joseph Lin1, Michael Garwood1, Kamil Ugurbil1, Walter Low

1CMRR, University of Minnesota, Minneapolis, Minnesota, USA

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                  2397.    Comparative Response to Focal Cerebral Ischemia of C57Blj6, Trek-1-/- And Traak-/- Mice

 

Christophe Laigle1, Angèle Viola1, Sylviane Confort-Gouny1, Yann Le Fur1, Nicolas Guy2, Michel Lazdunski2, Catherine Heurteaux2, Patrick J Cozzone1

1Centre de Résonance Magnétique Biologique et Médicale, UMR CNRS 6612, Marseille, France; 2Institut de Pharmacologie Moléculaire et Cellulaire (I.P.M.C.), UMR 6097, C.N.R.S/U.N.S.A, Valbonne, France

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                  2398.    Prediction and Prevention of Encephalopathy in Mouse Model of Glutaric Acidemia

 

William J. Zinnanti1, Jelena Lazovic2, Keith C. Cheng1

1The Pennsylvania State University, Hershey, Pennsylvania, USA; 2California Institute of Technology, Pasadena, California, USA

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                  2399.    MRM of Perfused Alzheimer’s Mice Hippocampal Slices

 

Peter Tek1, Shadi F. Othman1, Osama M. Abdullah1, Orly Lazarov1, Christopher Fall1, Richard L. Magin1

1University of Illinois at Chicago, Chicago, Illinois, USA

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                  2400.    MR Angiography Detects Cerebral Amyloid Angiopathy (CAA) Associated with Alterations of
                              Cerebral Blood Flow in Thalamic Vessels of APP23 Mice Modelling Alzheimer’s Disease

 

Nicolau Beckmann1, Estibaliz Capetillo-Zarate2, Sergey Larionov2, Matthias Staufenbiel1, Stefan Zurbruegg1, Dietmar R. Thal2

1Novartis Institutes for BioMedical Research, Basel, Switzerland; 2University of Bonn, Bonn, Germany

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                  2401.    31P MRS Study of Brain Creatine Kinase in Two Different Animal Models Simulating
                              Human Alzheimer‘s Disease and Vascular Dementia

 

Svatava Kasparova1, Ladislav Baciak1, Norbert Zilka2, Michal Novak2, Stefan Zbyn3, Jaromir Horecky4, Tibor Liptaj1

1Slovak University of Technology, Bratislava, Slovakia, Slovakia; 2Slovak Academy of Science, Bratislava, Slovakia, Slovakia; 3Medical University of Vienna, Viena, Austria, Austria; 4Slovak Medical University, Bratislava, Slovakia, Slovakia

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                  2402.    Viscoelastic Properties of the Brain in High Field MR Elastography - In-Vivo Application to
                               an Alzheimer's Mouse Model

 

Queenie C.C. Chan1, Benoit Larrat2, Xi Fei Yang1, Geng Li1, Edward S. Yang1, Ralph Sinkus2

1The University of Hong Kong, Pokfulam, Hong Kong; 2Universitˆm Paris VII, France

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                  2403.    An Iterative, Non-Linear Mouse Atlas for Mouse Brain Phenotyping in a Huntington's Disease Model

 

Stephen John Sawiak1, Guy B. Williams1, Nigel I. Wood2, A J. Morton2, T Adrian Carpenter1

1University of Cambridge, Cambridge, England, UK; 2University of Cambridge, England, UK

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                  2404.    Metabolic Fingerprints of Altered Brain Growth in a Rett Syndrome Mouse Model :
                              A 31P and 1H MRS Study of Tissue Extracts

 

Angèle Viola1, Véronique Saywell2, Laurent Villard2, Patrick J. Cozzone1, Norbert W. Lutz1

1Faculté de Médecine de Marseille, Université de la Méditerranée, Marseille, France; 2School of Medicine, Marseille, France

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                  2405.    Metabolic Magnetic Resonance Progression Markers of Neurodegeneration in the Transgenic
                              G93A-SOD1 Mouse Model of Amyotrophic Lateral Sclerosis

 

Heiko G. Niessen1, Grazyna Debska-Vielhaber1, Frank Angenstein1, Kerstin Sander2, Dieter Leibfritz3, Stefan Vielhaber1

1University of Magdeburg, Magdeburg, Germany; 2Leibniz-Institute for Neurobiology, Magdeburg, Germany; 3University of Bremen, Bremen, Germany

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                  2406.    Detection of Structural and Functional Changes in the Cortex of Bassoon-Mutant Mice by
                              MRI and 1H-NMR-Spectroscopy

 

Frank Angenstein1, 2, Heiko G. Niessen3, Juergen Goldschmidt1, Eckart D. Gundelfinger1, Liane Hilfert2, Werner Zuschratter1, Henning Scheich1

1Leibniz Institute for Neurobiology, Magdeburg, Germany; 2University of Magdeburg, Magdeburg, Germany; 3Boehringer Ingelheim Pharma GmbH & Co KG, Biberach, Germany

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                  2407.    In Vivo Characterization of Brain Phenotypes Associated with Two-Pore Domain K+ Channel
                             (K2P) Gene Disruption

 

Christophe Laigle1, Sylviane Confort-Gouny1, Yann Le Fur1, Nicolas Guy2, Michel Lazdunski2, Catherine Heurteaux2, Patrick J Cozzone1, Angèle Viola1

1Centre de Résonance Magnétique Biologique et Médicale, UMR CNRS 6612, Marseille, France; 2Institut de Pharmacologie Moléculaire et Cellulaire (I.P.M.C.), UMR 6097, C.N.R.S/U.N.S.A, Valbonne, France

 

 

MRI/MRS of Animal Models of White Matter Disease

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2408.    Serial Proton MRS Evaluation of Neurometabolism in a Mouse Model of Systemic Lupus Erythematosus (SLE)

 

Todd Atwood1, Nilamadhab Mishra1, Jian-Ming Zhu1

1Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA

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                  2409.    Characterization of Neurodegeneration in Experimental Autoimmune Encephalomyelitis
                              Induced Rat Using High Resolution DTI

 

Edward Sai Kam Hui1, Bing Hu1, Kevin Chuen Wing Chan1, Sha Mi2, Kwok Fai So1, Wu Tian Wu1, Ed Xuekui Wu1

1The University of Hong Kong, Pokfulam, Hong Kong; 2Biogen Idec, Cambridge, MA 02142, USA

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                  2410.    A Longitudinal Study of Myelin Oligodendryocyte Glycoprotein (MOG)-Induced EAE Using
                              Non-Invasive Imaging Techniques

 

Vamsidhar Chavakula1, Blair Cardigan Smith2, Angela Schellenberg3, Richard Buist3, Daniel Procissi1, Scott E. Fraser1, Russell E. Jacobs1, Melanie Martin2, 3, Carol Readhead1

1Caltech, Pasadena, California, USA; 2University of Winnipeg, Winnipeg, Manitoba, Canada; 3University of Manitoba, Winnipeg, Manitoba, Canada

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                  2411.    Quantitative Magnetization Transfer Imaging of Focal EAE Lesions

 

Martin Rausch1, Pernilla Lervik1, Tim Seabrook1, Anna Schubart1, Paul S. Tofts2

1Novartis Institutes for BioMedical Research, Basel, Switzerland; 2Brighton and Sussex Medical School, Brighton, UK

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                  2412.    Characterization of Myelin Damage in Multiple Sclerosis Using Myelin Water Imaging:
                              Insight from Simulations on a Four Pool Model of White Matter

 

Ives R. Levesque1, G. Bruce Pike1

1Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada

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                  2413.    USPIO Dynamics in an Animal Model of Multiple Sclerosis

 

Raoul David Oude Engberink1, Susanne van der Pol2, H E. de Vries2, Erwin L. Blezer1

1University Medical Center Utrecht, Utrecht, Netherlands; 2VU Medical Center, Amsterdam, Netherlands

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                  2414.    In Vivo MRI/MRS of PTEN-Null Mice - An Animal Model of Hypermyelination

 

Susann Boretius1, Sandra Goebbels2, Klaus-Armin Nave2, Jens Frahm1, Thomas Michaelis1

1Max-Planck-Institut fuer biophysikalische Chemie, Goettingen, Germany; 2Max-Planck-Institut fuer experimentelle Medizin, Goettingen, Germany

 

 

MRI/MRS of Animal Neuro Models:  Other

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2415.    Regional Metabolic Abnormalities as a Function of Age in Familial Amyotrophic Lateral
                              Sclerosis (FALS) Mice Assessed Using 1H Magnetic Resonance Spectroscopy (1H MRS)

 

Ji-Kyung Choi1, Alpaslan Dedeoglu2, Bruce G. Jenkins3

1MGH-NMR Center and Matinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA; 2VA Medical Center, Bedford, Massachusetts, USA; 3MGH-NMR Center and Martinos Center for Biomedical Imaging,

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                  2416.    Evolution of Mice Brain Metabolism After a Convulsive Dose of Soman : A HRMAS 1H-NMR Study

 

Florence Fauvelle1, Guy Testylier1, Herald Rabeson2, Danielle Graveron-demilly2, Annie Foquin1, Pierre Carpentier1, Frédéric dorandeu1

1CRSSA, La Tronche, France; 2Université Lyon1, Villeurbanne, France

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                  2417.    Diffusion in the Rat Cerebral Cortex During Pilocarpine-Induced Status Epilepticus

 

Ivan Vorisek1, 2, Karel Slais1, Lesia Dmytrenko1, Eva Sykova1, 2

1Institute of Experimental Medicine ASCR, Prague, Czech Republic; 2Charles University, 2nd Medical Faculty, Prague, Czech Republic

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                  2418.    MR Measurements of Diffusion, Perfusion and T2 with Proteomic Analysis in the
                              Hippocampus Following Status Epilepticus in the Rat Lithium-Pilocapine Model

 

ManKin Choy1, Rodney C. Scott1, David L. Thomas2, David G. Gadian1, Nicholas Greene1, Robin Wait3, Kit-Yi Leung4, Mark F. Lythgoe1

1UCL Institute of Child Health, London, UK; 2UCL, London, UK; 3Imperial College Schhol of Science, Technology and Medicine, London, UK; 4Bart's and the London, London, UK

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                  2419.    Prospective Brain T2 Relaxometry and Diffusion Tensor Imaging in a Rat Model of

                              Early-Life Febrile Convulsions

 

Jacobus FA Jansen1, 2, Evi P. Lemmens1, Govert Hoogland1, Olaf E. Schijns1, Ward Jennekens2, Gustav J. Strijkers2, Jeanine J. Prompers2, Jo W. Habets2, M Eline Kooi1, Walter H. Backes1, Klaas Nicolay2

1Maastricht University Hospital, Maastricht, Netherlands; 2Eindhoven University of Technology, Eindhoven, Netherlands

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                  2420.    Infection with Plasmodium Berghei ANKA Leads to Brain Damage in Mice Resistant to Cerebral Malaria

 

Marie-France Penet1, Frank Kober1, Sylviane Confort-Gouny1, Yann Le Fur1, Christiane Dalmasso1, Nicolas Coltel2, Agnès Liprandi3, Jean-Marc Gulian3, Georges E Grau4, Patrick J Cozzone1, Angèle Viola1

1Centre de Résonance Magnétique Biologique et Médicale, UMR CNRS 6612, Marseille, France; 2UMR CNRS 6020, Marseille, France; 3Hôpital la Timone, Marseille, Marseille, France; 4The University of Sydney, Sydney, Australia

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                  2421.    Effect of Diet and Exercise on MR Outcomes of a Model of Vascular Dementia in Aged Rats

 

Richard Buist1, Kathy McKay2, Garry Chernenko2, Dale Corbett2, James Peeling1

1University of Manitoba, Winnipeg, Manitoba, Canada; 2Memorial University, St. John's, Newfoundland, Canada

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                  2422.    Neuroprotective Effects of Modafinil in a Nonhuman Primate Parkinson Model

 

Sanneke A.M. van Vliet1, 2, Erwin L.A. Blezer3, Marjan Jongsma1, Raymond A.P. van Wersch1, Ingrid H.C.H.M. Philippens1

1TNO Defense, security and safety, Rijswijk, Netherlands; 2Institute of Pharmaceutical Sciences and Rudolf Magnus Institute of Neurosciences, Utrecht, Netherlands; 3University Medical Center Utrecht, Utrecht, Netherlands

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                  2423.    Pathological Change in Nigrostriatal Pathway in MPTP Induced Parkinson's Disease Animal

                              Model Using DTI and MRS

 

Yu-Ying Tung1, 2, Ching-Po Lin1, Chen Chang2

1Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan; 2Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

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                  2424.    Neuroprotective Composition Effective for Ameliorating Mental Decline: Volume MR Image In Vivo

 

Geng Li1, Xi-Fei Yang1, Queenie CC Chan1, Gina J. Gu1, Edward S. Yang1

1The University of Hong Kong, HK, HKSAR, People’s Republic of China

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                  2425.    Assessment of the Protective Effect of L-Carnitine in Hepatic: Improvements of Muscle and
                              Brain Mitochondrial and Fatty Acid Metabolism

 

Claudia Zwingmann1, Sven Gottschalk1, Wenlei Jiang1, Roger Butterworth1, Dieter Leibfritz2

1Hospital Saint-Luc, Montreal, Quebec, Canada; 2University of Bremen, Bremen, Germany

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                  2426.    Cocaine-Induced Cerebral ADC and Hemodynamic Changes Between Cocaine-Naïve Rats and
                              Rats with Repetitive Cocaine Treatment

 

Congwu Du1, 2, Yu Ma1, Mei Yu1, David S. Smith1, Zhongchi Luo1, 3, Helene Benveniste1, 2

1Brookhaven National Laboratory, Upton, New York, USA; 2State Univ of New York at Stony Brook, Stony Brook, New York, USA; 3State University of New York at Stony Brook, Stony Brook, New York, USA

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                  2427.    Cerebral Metabolism of Adult Marmoset Monkeys After Intrauterine Hyperexposure to Dexamethasone

 

Thomas Michaelis1, Alireza Abaei1, Roland Tammer1, Susann Boretius1, Cristina Schlumbohm2, Eberhard Fuchs2, Jens Frahm1

1Biomedizinische NMR Forschungs GmbH, Goettingen, Germany; 2Deutsches Primatenzentrum, Goettingen, Germany

 

 

DTI Animal Neuro Models

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2428.    Decreased Axial Diffusivity as a Biomarker of Axonal Injury in the Spinal Cord White Matter of
                             Mice with EAE Validated with Immunofluorescence

 

Matthew D. Budde1, Joong Kim, Mingqiang Xie, Ariel Liang, Anne H. Cross, Sheng-Kwei Song

1Washington University, St Louis, Missouri, USA

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                  2429.    High Temporal Resolution Diffusion MR Imaging of the Mouse Spinal Cord Using Echo Planar Imaging

 

Virginie Callot1, Guillaume Duhamel1, Patrick J. Cozzone1, Frank Kober1

1Centre de Résonance Magnétique Biologique et Médicale (CRMBM), Marseille, France

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                  2430.    Acute Axial Diffusivity Changes Predict Long Term Locomotor Function Recovery After Spinal
                              Cord Injury

 

Qing Wang1, Joong Hee Kim1, David N. Loy2, Sheng-Kwei Song3

1Washington University in St.Louis, Saint Louis, Missouri, USA; 2Washington University in St. Louis, Saint  Louis, Missouri, USA; 3Washington University in St. Louis, Saint Louis, Missouri, USA

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                  2431.    In Vivo MRI of Axonal Damage with Subtle Myelin Defects in PLP-Null Mice

 

Susann Boretius1, Sandra Goebbels2, Agnieszka Burzynska1, Roland Tammer1, Klaus-Armin Nave2, Jens Frahm1, Thomas Michaelis1

1Max-Planck-Institut fuer biophysikalische Chemie, Goettingen, Germany; 2Max-Planck-Institut fuer experimentelle Medizin, Goettingen, Germany

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                  2432.    Temporal and Spatial Evolution of Wallerian Degeneration in Central Nervous System
                              Detected Using DTI

 

Shu-Wei Sun1, Anne H. Cross1, Sheng-Kwei Song1

1Washington University School of Medicine, St. Louis, Missouri, USA

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                  2433.    In Vivo Diffusion Kurtosis Imaging of Rat Brain

 

Edward Sai Kam Hui1, Hanzhang Lu2, Jens H. Jensen3, Joseph A. Helpern4, Kevin Chuen Wing Chan1, Ed Xuekui Wu1

1The University of Hong Kong, Pokfulam, Hong Kong; 2UT Southwestern Medical Centre, Dallas, TX 75390, USA; 3New York University School of Medicine, New York, USA; 4Centre for Biomedical Imaging, New York University, New York, USA

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                  2434.    Diffusion Tensor Imaging of Spinal Cord Injury:  Regional Differences in White Matter
                              Damage During the Hyperacute Phase

 

David Neil Loy1, Joong Hee Kim, Kathryn Trinkaus, Robert E. Schmidt, Sheng-Kwei Song2

1Washington University, Saint Louis, Missouri, USA; 2Washington University, S, Missouri

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                  2435.    White Matter Damage in Nijmegen Breakage Syndrome by Diffusion and T2 MRI

 

Yaniv Assaf1, Ronit Galron1, Itai Shapira1, Tamar Blumenfeld-Katzir1, Zhao-Qi Wang2, Yosef Shiloh1, Ari Barzilai1

1Tel Aviv University, Tel Aviv, Israel; 2Fritz Lipmann Institute, Jena, Germany

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                  2436.    Reversible Axonal Injury Detected by DTI and Immnohistochemistry

 

Hsiao-Fang Liang1, Shu-Wei Sun1, Pei-Ching Chang2, Chen Chang2, Anne H. Cross1, Sheng-Kwei Song1

1Washington University School of Medicine, St. Louis, Missouri, USA; 2Academia Sinica, Taipei, Taiwan, Taiwan

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                  2437.    In Vivo DTI Study of Developmental Rat Brain

 

Ho-fai Lau1, Edward Saikam Hui1, Hiu-fai Siu1, Jian Yang1, Pek-lan Khong1, Ed Xuekui Wu1

1The University of Hong Kong, Pokfulam, Hong Kong

 

 

ME MRI Animal Models

Hall 14.1                     Wednesday 13:30 - 15:30

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                  2438.    Visualization of Mouse Corticospinal Tract by Manganese-Enhanced Magnetic Resonance Imaging

 

Zhixin L. Huang1, Yong-Yue He1, Mehmet Bilgen1

1The University of Kansas Medical Center, Kansas City, Kansas, USA

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                  2439.    Functional Imaging of Olfactory Neural Network In Vivo Using Manganese Enhanced MRI:
                              A Comparative In Vivo Study Between Normal and Anosmia Rat Models

 

Yoo Jeong Yim1, Hyun Jong Lee1, Hyung-Jin Kim1, Hun-Jong Dhong1, Seung Kyu Chung1, Keun-Ho Lim2, Ki-Soo Kim3, Jung Hee Lee1

1Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; 2Asan Institutes for Life Science, University of Ulsan, Seoul, Republic of Korea; 3Asan Medican Center, University of Ulsan, Seoul, Republic of Korea

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                  2440.    Changes of Proton T1 and T2 Relaxation Times of Cerebral Metabolites Induced by
                              Repeated Manganese Treatments in Rat

 

Xuxia Wang1, Chaoni Xiao1, Hao Lei1

1Wuhan Institute of Physics & Mathematics, Chinese Academy of Science, Wuhan, Hubei, People’s Republic of China

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                  2441.    Quantitative Assessment of Axonal Transport Integrity in the Mouse Brain In Vivo Using MEMRI at 9.4 T

 

Sang-Pil Lee1

1University of Kansas Medical Center, Kansas City, Kansas, USA

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                  2442.    Manganese Enhanced MRI of Olfactory Pathway in Developing Rats

 

Waqas Majeed1, Matthew Magnuson1, Shella Keilholz1

1Georgia Institue of Technology / Emory University, Atlanta, Georgia, USA

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                  2443.    Transportation of Mn2+ in the Brain of Rats with Exclusive Caudoputaminal Lesions After
                              Transient Focal Cerebral Ischmeia

 

Fang Fang1, Li Wei1, Cheng Jiang2, Hao Lei1

1Wuhan Institute of Physics & Mathematics, Chinese Academy of Sciences, Wuhan, Hubei, People’s Republic of China; 2Wuhan University, Wuhan, Hubei, People’s Republic of China

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                  2444.    High Dose of Mn2+ Injected Intracerebrally Causes Neuronal Losses in the Ventral Tegmental
                              Area of Rat

 

Yingxia Li1, Fang Fang1, Xuxia Wang1, Hao Lei1

1Wuhan Institute of Physics & Mathematics, Chinese Academy of Science, Wuhan, Hubei, People’s Republic of China

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                  2445.    Influence of Mn2+ Concentration on Transport Rates

 

Alison Thieme1, Lingyun Hu1, Cynthia Massaad1, Karen Smith1, Robia G. Pautler1

1Baylor College of Medicine, Houston, Texas, USA

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                  2446.    Tracing Olfactory Neural Circuits In Vivo Using 3D Manganese Enhanced MRI

 

Yoo Jeong Yim1, Hyun Jong Lee1, Hyung-Jin Kim1, Hun-Jong Dhong1, Seung Kyu Chung1, Keun-Ho Lim2, Ki-Soo Kim3, Jung Hee Lee1

1Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea; 2Asan Institutes for Life Science, University of Ulsan, Seoul, Republic of Korea; 3Asan Medican Center, University of Ulsan, Seoul, Republic of Korea

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                  2447.    Mapping the Plasticity of the Striatonigral Pathway in a Transgenic Mice Model Using MEMRI

 

Ke Fang1, 2, Douglas Whyte1, Ilse Gantois1, Hong Wang1, Qizhu Wu1, Jasna Ribic1, Jyoti Lodhia1, John Drago1, Gary Egan1

1University of Melbourne, Melbourne, Australia; 2The Royal Children's Hospital, Melbourne, Australia

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                  2448.    T1-Mapped Acute Cocaine-Induced Brain Activation with Systemic Administrated
                              Manganese-Enhanced MRI

 

Xiping Liu1, Gaohong Wu2, Shi-Jiang Li2

1Medical College of Wisconsin, Milwaukee, Wisconsin, USA; 2Medical College of Wisconsin, Wisconsin, USA

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                  2449.    Does MEMRI Detect Apoptosis in the Rat Neonatal Hypoxic-Ischemic Stroke Model?

 

Marius Wideroe1, Christian Brekken1, Tina Bugge Pedersen1, Annemieke Kavelaars2, Jon Skranes1, Cobi Heijnen2, Ann-Mari Brubakk1

1Norwegian University of Science and Technology, Trondheim, Norway; 2University Medical Center Utrecht, Utrecht, Netherlands

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                  2450.    Characterization of the 6-OHDA Model of Parkinson’s Disease Using Manganese-Enhanced MRI

 

Maria Adele Rueger1, Jeeva P. Munasinghe1, Alan P. Koretsky1, Ronald D. McKay1

1NIH, Bethesda, Maryland, USA

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                  2451.    Fractionated Manganese-Enhanced MRI

 

Nicholas Adam Bock1, Julie B. Mackel1, Afonso C. Silva1

1National Institutes of Health, Bethesda, Maryland, USA

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                  2452.    Manganese-Enhanced MRI Reveals Multiple Cellular and Vascular Layers in Normal and
                              Degenerated Retinas

 

Govind Nair1, 2, Haiying Cheng2, Moon Kim2, Tsukasa Nagaoka2, Darin E. Olson2, Peter Thule2, Machelle T. Pardue2, Timothy Q. Duong2

1University of Massachusetts, Worcester, Massachusetts, USA; 2Emory University, Atlanta, Georgia, USA

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                  2453.    MEMRI Reveals Plasticity Changes in the Auditory Midbrains of Mice After Two-Tone Rearing

 

Xin Yu1, Dan H. Sanes2, Jing Zou3, Orlando Aristizábal1, Youssef Wadghiri Zaim1, Daniel H. Turnbull1

1New York University School of Medicine, New York, New York, USA; 2New York University, New York, New York, USA; 3University of Maryland College Park, College Park, Maryland, USA

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                  2454.    Laminar Specific MEMRI Enhancement of the Rat Spinal Cord In Vivo

 

Galit Pelled1, Stasia A. Anderson1, Michael J. Iadarola1, Alan P. Koretsky1

1National Institutes of Health, Bethesda, Maryland, USA

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                  2455.    Manganese-Enhanced MRI Detects Distinct Patterns of Neuronal Activation Following Anorexigenic
                              Gut Hormone Administration

 

James R. Parkinson1, Owais Bashir Chaudhri1, Amy H. Herlihy2, Yu-Ting Kuo2, 3, Jimmy D. Bell2, Po-Wah So2, Waljit S. Dhillo1, Sarah A. Stanley1, Mohammad A. Ghatei1, Stephen R. Bloom1

1Imperial College London, Hammersmith Hospital, London, UK; 2MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, London, UK; 3School of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

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                  2456.    Determination of Laminar Specific Tracing of Somatosensory Pathways Using Manganese
                              Enhanced MRI

 

Jason Tucciarone1, Galit Pelled1, Kai Hsiang Chuang1, Alan P. Koretsky1

1National Institutes of Health, Bethesda, Maryland, USA

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                  2457.    Functional Mapping of Rat Barrel Activation Following Whisker Stimulation Using
                              Activity-Induced Manganese-Dependent Contrast

 

Jun-Cheng Weng1, Jyh-Horng Chen1, Pai-Feng Yang1, Wen-Yih Isaac Tseng2

1National Taiwan University, Taipei, Taiwan; 2National Taiwan University College of Medicine, Taipei, Taiwan

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                  2458.    Manganese-Enhanced MRI of Axon Regeneration by Peptide Nanofiber Scaffold Induction

 

Kevin Chuen Wing Chan1, Yu Xiang Liang1, Edward Saikam Hui1, Phillis W. Kau1, Rutledge G. Ellis-Behnke1, 2, Gerald E. Schneider2, Kwok Fai So1, Ed Xue Kui Wu1

1The University of Hong Kong, Pokfulam, Hong Kong; 2Massachusetts Institute of Technology, Cambridge, Massachusetts, USA

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                  2459.    Evaluation of Glaucomatous Optic Nerve Using In Vivo Manganese-Enhanced MRI

 

Kevin Chuen Wing Chan1, Sheryle Q. Fu1, Edward Sai Kam Hui1, Rachel S. Li1, Matthew Man Hin Cheung1, Darrell Ting Hung Li1, Kwok Fai So1, Ed Xue Kui Wu1

1The University of Hong Kong, Pokfulam, Hong Kong

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                  2460.    Monitoring Treatment Effects in Transgenic Mouse Model of Alzheimer’s Disease Using MRMI

 

Malgorzata Marjanska1, Thomas M. Wengenack2, Denise A. Reyes2, Geoffrey L. Curran2, Jan Grimm3, Joseph Lin1, Gregory M. Preboske2, Joseph F. Poduslo2, Michael Garwood1, Clifford R. Jack, Jr. 2

1Unviersity of Minnesota, Minneapolis, Minnesota, USA; 2Mayo Clinic College of Medicine, Rochester, Minnesota, USA; 3Rinat Neuroscience Corporation, South San Francisco, California, USA

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                  2461.    Manganese-Enhanced MRI (MEMRI) and Diffusion-Weighted MRI Mismatch in the Absence of a
                              Specific Neuronal Stimulus

 

David Bennett1, Nils Henninger2, 3, Marc Fisher2, 4, Chris Sotak1, 2

1Worcester Polytechnic Institute, Worcester, Massachusetts, USA; 2University of Massachusetts Medical School, Worcester, Massachusetts, USA; 3University of Massachusetts Memorial Healthcare, Worcester, Massachusetts, USA; 4University of Massachusetts Memorial Health Care, Worcester, Massachusetts, USA

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                  2462.    Preservation of Manganese Induced Contrast in Fixed Rat Brain

 

Kathrine Skak Madsen1, David Alberg Holm1, Lise Vejby Søgaard1, Ian John Rowland1

1Hvidovre Hospital, Copenhagen, Denmark

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                  2463.    In Vivo Assessment of Axonal Transport in Diabetic Mice Using Manganese-Enhanced MRI (MEMRI)

 

Faridis Serrano1, Tomoya Terashima, Lawrence C. B. Chan2, Robia G. Pautler1

1Baylor College of Medicine, Houston, Texas, USA; 2Baylor College of Medicine, Texas

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                  2464.    In Vivo Brain Connectivity: Optimization of Manganese Enhanced MRI for Neuronal Tract Tracing

 

Santiago Canals1, Michael Beyerlein1, Anna Lena Keller1, Yusuke Murayama1, Nikos K. Logothetis1

1Max Planck Institute for Biological Cybernetics, Tübingen, Germany