| Weekend Educational Course:
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| MR Physics for Physicists |
| Organizers: Michael H.
Buonocore, M.D., Ph.D., Michael Markl, Ph.D. and Lawrence L.
Wald, M.D., Ph.D. |
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| Skill Level:
Intermediate – Advanced |
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| Saturday, 18 April 2009 |
| 08:30 - 18:00 |
|
| OVERVIEW |
|
This one day course will
explore the physical methods and mathematical models
that underlie nearly all research and development in MRI
and MR spectroscopy. Lectures will cover the general
topics of spin physics, signal detection, generation of
contrast, and imaging physics. |
| |
Specific topics include:
- Quantum mechanical and semi-classical equations
for describing spin dynamics;
- The density matrix formalism and its
applications in MRS;
- Physical mechanisms of hyper polarization;
- Radiofrequency field equations and reciprocity
laws for signal detection;
- Sources of noise and limits to SNR;
- Tissue microstructure and molecular factors that
govern image contrast;
- Physical mechanism of exogenous and endogenous
contrast agents;
- Methods and models to describe magnetization
exchange;
- Physics and mathematics for susceptibility
weighted imaging;
- Mathematical description of dynamic equilibrium
in fast sequences;
- Calculation of effective relaxation times in
fast sequences;
- Applications of advanced electromagnetic theory
in imaging;
- Use of magnetization phase in applications;
- Methods for quantitative parameter mapping, and;
- Mathematical formalisms for RF pulse design.
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| EDUCATIONAL OBJECTIVES
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Upon completion of this
course, participants should be able to:
- Describe and derive equations for spin and
magnetization dynamics, and list their main
applications;
- List physical mechanisms of spin relaxation and
polarization;
- Explain tissue microstructure responsible for
relaxation differences;
- Describe mathematical models used for
understanding image contrast generation and
parameter mapping; and
- Describe mathematical models used for RF pulse
design.
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| Saturday, 18 April 2009 |
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SPIN PHYSICS
|
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| 08:30 |
Quantum Mechanical
and Semi-Classical Equations for Spin Dynamics |
Valerij
G. Kiselev, Ph.D. |
| 09:00 |
The Density Matrix
Formalism and its Applications in MRS |
Thomas
Ernst, Ph.D. |
| 09:30 |
Physical Mechanisms
for Hyperpolarization |
J.H.
Ardenkjaier-Larsen, Ph.D. |
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SIGNAL DETECTION
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|
| 10:00 |
Theory of RF
Reciprocity |
Greig C.
Scott, Ph.D. |
| 10:30 |
Break - Meet the
Teachers |
|
| 10:50 |
Sources of Noise and
Limits of SNR |
Klaas
Pruessmann, Ph.D. |
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GENERATION OF
CONTRAST |
|
| 11:20 |
Tissue
Microstructure and Molecular Factors that Govern MRI
Contrast |
Christopher C. Quarles, Ph.D. |
| 11:50 |
Physical Mechanisms
of Contrast Agents |
Peter M.
Jakob, Ph.D. |
| 12:20 |
Break - Meet the
Teachers |
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| 13:40 |
Physical Models for
Magnetization Exchange (Magnetization Transfer) |
Vasily
L. Yarnykh, Ph.D. |
| 14:10 |
Physics and
Mathematics Challenges in Susceptibility Weighted
Imaging |
Jurgen
R. Reichenbach, Ph.D. |
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IMAGING PHYSICS
|
|
| 14:40 |
Mathematical
Description for Dynamic Equilibrium in Fast
Sequences |
Oliver
Bieri, Ph.D. |
| 15:10 |
Calculation of
Effective Relaxation Times and Weighting in Fast
Sequences |
Matthias
Weigel, Ph.D. |
| 15:40 |
Break - Meet the
Teachers |
|
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| 16:00 |
Applications of
Advanced Electromagnetic Theory |
Richard
W. Bowtell, Ph.D. |
| 16:30 |
Use of Magnetization
Phase in Applications |
Oliver
Wieben, Ph.D. |
| 17:00 |
Methods for
Quantitative Relaxation Parameter Mapping |
Paul S.
Tofts, Ph.D. |
| 17:30 |
Mathematical
Formalisms for RF Pulse Design |
Adam B.
Kerr, Ph.D. |
| 18:00 |
Adjournment - Meet
the Teachers |
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