Neurovascular Angiography Techniques - Clinical Studies
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Wednesday May 11th
Room 511A-C |
10:30 - 12:30 |
Moderators: |
Timothy J. Carroll and Oliver Weiben |
10:30 |
358. |
A New High Resolution MR
DSA Protocol for Intracranial Vascular Malformations
Parmede Vakil1, Sameer A Ansari2,
Michael C Hurley2, and Timothy J Carroll2
1Biomedical Engineering, Northwestern
University, Chicago, IL, United States, 2Radiology,
Northwestern University, Chicago, IL, United States
A novel, high resolution MR DSA protocol is presented
for visualizing high-flow intracranial vascular
malformations. In addition, a gradient spoiling
technique is presented to be used with RF-spoiling for
eliminating artifacts associated with 2D radial FLASH
MRI.
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10:42 |
359. |
Unenhanced four
dimensional magnetic resonance angiography: preliminary
experience in patients with cerebrovascular disorders
Kaiyuan Zhang1, Jie Lu1, Jing An2,
Mo Zhang1, Xiaoming Bi3, and
Kuncheng Li1
1Department of Radiology, Xuanwu Hospital,
Capital Medical University, Beijing, Beijing, China,
People's Republic of, 2Siemens
Mindit Magnetic Resonance, Shenzhen, Guangdong, China,
People's Republic of, 3Cardiovascular
MR R&D, Siemens Healthcare, Chicago, Illinois, United
States
The purpose of this work is to evaluate the feasibility
of using NCE-4DMRA for the diagnosis of cerebral
vascular steno-occlusive disease and vascular
malformations.The 4DMRA shows the abnormal inflow and
shape of different cerebrovascular disorders.The
technique provide a safe alternativ without ionizing
radiation, risk of catherization and reactions to
contrast agent as in DSA.
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10:54 |
360. |
Time-Resolved Angiography
with a Highly Undersampled Multi-echo 3D Radial Trajectory
Gregory R Lee1, Nicole Seiberlich1,
Jeffrey L Sunshine1,2, Timothy J. Carroll3,4,
and Mark A Griswold1,5
1Radiology, Case Western Reserve University,
Cleveland, OH, United States, 2Radiology,
University Hospitals Case Medical Center, Cleveland, OH,
United States,3Radiology, Northwestern
University, Chicago, IL, United States, 4Biomedical
Engineering, Northwestern University, Chicago, IL,
United States, 5Biomedical
Engineering, Case Western Reserve University, Cleveland,
OH, United States
3D Time-Resolved angiography remains challenging due to
the high spatial and temporal resolutions required. In
the present work, a multishot 3D radial VIPR acquisition
with multi-echo readout and pseudorandom undersampling
is combined with the recently developed GraDeS
reconstruction algorithm. GraDeS allows the
reconstruction of sparse images from highly undersampled
data. A B0 fieldmap for correction of susceptibility
artifact was derived from the same dataset. The
resulting angiograms demonstrate clear arterial and
venous separation. 1 mm^3 isotropic resolution is
achieved at acceleration factors of 100-400 (1.1 s /
0.27s per frame) without the use of view sharing or a
composite image.
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11:06 |
361. |
High Resolution
Hemodynamics of Small Intracranial Aneurysms with Phase
Contrast Stack of Stars
Steven Kecskemeti1, Kevin Johnson1,
Yijing Wu1, Patrick Turski2, and
Oliver Wieben1
1Medical Physics, University of Wisconsin -
Madison, Madison, Wisconsin, United States, 2Radiology,
University of Wisconsin - Madison, Madison, Wisconsin,
United States
A hybrid radial-Cartesian k-space trajectory was used to
acquire cine 4D PC MR with ultra-high spatial resolution
for anatomical and hemodynamic visualization of small
intracranial aneurysms. Specifically, we targeted 12
aneurysms of sizes 2-10mm, with 7 of them 4mm or less.
This abstract demonstrates the improved hemodynamic
visualization and quantification compared to lower
resolution exams typically acquired with Cartesian exams
of the same scan length.
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11:18 |
362. |
Visualizing Small
Intra-cranial Arteries using TOF with Compressed Sensing
Jerome Yerly1,2, Michel Louis Lauzon2,3,
and Richard Frayne2,3
1Department of Electrical and Computer
Engineering, University of Calgary, Calgary, AB, Canada, 2Foothills
Medical Centre, Seaman Family MR Research Centre,
Calgary, AB, Canada, 3Departments
of Radiology, and Clinical Neurosciences, University of
Calgary, Calgary, AB, Canada
Time-of-flight (TOF) MRA has been successfully used to
diagnose stenoses in large arteries. However, imaging
stenoses in smaller arteries requires acquiring
high-resolution images, which is particularly
challenging in TOF data acquisition because of the
tradeoff between spatial resolution, acquisition time
and signal-to-noise ratio (SNR). Accelerated approaches
such as compressed sensing (CS) may prove favorable for
accurate reconstruction of undersampled k-space
datasets. Here, we investigated the potential of
improving the spatial resolution by using the CS
paradigm to acquire and reconstruct vastly undersampled
high-resolution TOF k-space datasets, while maintaining
reasonable scan time and SNR.
|
11:30 |
363. |
High resolution time-of
flight MRA using slice selective saturation transfer
contrast and water excitation technique for the
visualization of the Lenticulostriate arteries at 1,5T
Faiza Admiraal-Behloul1, Evert Blink1,
Bei Zhang1, and Mitsue Miyazaki2
1MR-BU, Toshiba Medical Systems Europe,
Zoetermeer, Netherlands, 2Toshiba
Medical Research Institute, Vernon Hills, Illinois,
United States
It has been well accepted that Lenticulostriate arteries
(LSAs) are nearly impossible to visualize on 1,5T and
very difficult at 3T clinical MR systems in healthy
volunteers. Therefore, LSAs are mainly studied at 7T.
The aim of this preliminary study was to investigate the
ability of high resolution 3D time-of flight (TOF)
angiography to visualize the LSAs at 1,5 T,using a
Slice-Selective Off-Resonance Sinc Pulse-Saturation
Transfer Contrast with inclined profile selective
excitation and water excitation technique.
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11:42 |
364. |
Superselective
MR-angiography based on pseudo-continuous arterial spin
labeling and first applications in AVM patients
Michael Helle1, Susanne Rüfer1,
Wouter Teeuwisse2, Olav Jansen1,
David Gordon Norris3,4, and Matthias van Osch2
1Institute for Neuroradiology,
Christian-Albrechts-Universität, UK-SH, Kiel, Germany, 2C.J.
Gorter Center for high field MRI, Department of
Radiology, Leiden University Medical Center, Leiden,
Netherlands, 3Donders
Institute for Brain, Cognition and Behaviour, Radboud
University Nijmegen, Nijmegen, Netherlands, 4Erwin
L. Hahn Institute for Magnetic Resonance Imaging, Essen,
Germany
Intra-arterial digital subtraction angiography (DSA) is
considered the gold-standard for cerebral angiography
but the procedure is invasive and bears the risk of
severe complications. Existing MR angiography techniques
offer non-invasive approaches but the selectivity is
restricted to major brain feeding vessels. In this
study, we combined superselective arterial spin labeling
with an optimized image acquisition which was applied in
healthy volunteers as well as in patients suffering from
arterio-venous-malformation (AVM). This approach for
selective ASL angiography not only mimics DSA but also
combines advantages of superselective labeling and
high-resolution 3D image acquisition in a complete
non-invasive way.
|
11:54 |
365. |
Application of Temporally
Constrained Compressed Sensing for High Spatial and Temporal
Resolution Intracranial CE MRA
Julia V Velikina1, Kevin M Johnson1,
Steven R Kecskemeti1, Patrick A Turski2,
and Alexey A Samsonov1,2
1Medical Physics, University of Wisconsin -
Madison, Madison, WI, United States, 2Radiology,
University of Wisconsin - Madison
We apply temporally constrained compressed sensing
reconstruction of hybrid radial (in-plane)/Cartesian
(through-plane) data acquisition to time-resolved
contrast-enhanced MRA. We were able to obtain images
with high spatial (0.86x0.86x2 mm) and temporal (1.2 s)
resolution in patients with intracranial aneurysms.
|
12:06 |
366. |
Fast Analysis of Vessel
Encoded ASL Perfusion and Angiographic Images
Michael A Chappell1,2, Tom W Okell2,
Stephen J Payne1, Peter Jezzard2,
and Mark W Woolrich2
1Institute of Biomedical Engineering,
University of Oxford, Oxford, United Kingdom, 2FMRIB
Centre, University of Oxford, Oxford, United Kingdom
Vessel Encoded Arterial Spin Labelling (VEASL)
preparations permit vessel selectivity for both dynamic
angiographic and perfusion acquisitions. The calculation
of flow contributions can be very sensitive to choice of
encoding and subject position, this can be accounted for
using a recently proposed general framework for VEASL
analysis. However, the original implementation of this
framework was too slow for many practical applications.
Here faster solutions to the framework were sought that
reduced computational time from hours to minutes or in
some cases seconds without substantially affecting the
accuracy of the resulting images.
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12:18 |
367. |
Validation of a simple
anatomical classification method of the circle of Willis: a
MR angiographical and selective arterial spin labeling MRI
study at 3 Tesla
Jeroen Hendrikse1, Xavier Golay2,
and Esben Thade Petersen3
1UMC, Radiology, Utrecht, Netherlands, 2Institute
of Neurology, UCL, London, United Kingdom, 3CIRC,
NUS-A*STAR, Singapore
In this work, we introduce a simple classification
method and evaluated its hemodynamic relevance in terms
of flow contributions to the anterior and posterior
cerebral arteries. Five variants are based on MR
angiographic diameter comparisons on the posterior side
of the circle of Willis: P1 absent, P1 PCoM,
PCoM absent and on the anterior side: A1 absent, A1ACoM,
ACoM absent. We correlated the results of our circle of
Willis classification method with the perfusion
territory contributions of the carotid and
vertebrobasilar arteries measured with selective
arterial spin labeling (ASL) MRI, in a series of
subacute stroke patients.
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