Traditional Posters
: Pulse Sequences, Reconstruction & Analysis
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Click on
to view the
abstract pdf and click on
to view the pdf of the poster viewable in the poster hall.
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Artifacts & Correction: Phase Processing & SWI
Wednesday May 11th
Exhibition Hall |
13:30 - 15:30 |
2663. |
Improved
forward calculation for phase artifacts removal
in susceptibility mapping
Saifeng Liu1, Jaladhar Neelavalli2,
Weili Zheng3, and Ewart Mark
Haacke2,4
1School of Biomedical
Engineering, McMaster University, Hamilton,
Ontario, Canada, 2The
Magnetic Resonance Imaging Institute for
Biomedical Research, Detroit, Michigan,
United States,3Biomedical
Engineering, Wayne State University,
Detroit, Michigan, United States, 4Academic
Radiology, Wayne State University, Detroit,
Michigan, United States
The forward calculation enables us to
predict and remove the background field
variation. However, it becomes insufficient
when the eddy currents are considerable. We
proposed to add an polynomial fitting to the
forward calculation. With this new method,
the background filed variation can be
properly fitted and most of the phase
artifacts were removed. This allows us to
use a high-pass filter with smaller size to
reduce the error in susceptibility mapping.
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2664. |
Matching
Pursuit Iterative Dipole Based Filter of
Background Fields in Phase Imaging
José P. Marques1,2, Yves Wiaux3,4,
and Rolf Gruetter1,5
1Laboratory for Functional and
Metabolic Imaging, Ecole Polytechnique
Fédérale de Lausanne, Lausanne, Vaud,
Switzerland, 2Department
of Radiology, University of Lausanne,
Lausanne, Vaud, Switzerland, 3Signal
Processing Laboratory 5, Ecole Polytechnique
Fédérale de Lausanne, Lausanne, Switzerland, 4Medical
Image Processing Laboratory, University of
Geneva, Geneva, Switzerland, 5Department
of Radiology, University of Lausanne and
Geneva, Switzerland
In this abstract a fast iterative method to
filter the large background phase shifts of
susceptibility origin in phase imaging is
presented. The algorithm is based on the
matching pursuit iterative methodology to
solve the ill posed inverse problem of
finding a susceptibility distribution
outside that can explain the field inside
the region of interest. The algorithm is
demonstrated both in synthetic and in vivo
brain data acquired at 7T.
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2665. |
Reducing
Artifacts in SWI based MR Venography - Post
Processing Technique to Compensate for the
Signal Loss
Se Rim Park1, Ung Jang1,2,
and Dosik Hwang1,2
1School of Electrical and
Electronic Engineering, Yonsei University,
Seoul, Korea, Republic of, 2Yonsei
University
IN SWI MR venography, long echo time might
be desired for high contrast. However,
longer echo time eventually introduces
artifacts mainly caused because of
unexpected macroscopic field inhomogeneity,
especially around the orbito-frontal cortex.
In order to correct the image, for the first
step, local inhomogeneity is directly
calculated after the signal acquisition, and
Local Field Gradient (LFG) map is created.
Then each signal is corrected to certain
degree according to this LFG value so that
the optimum image is restored.
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2666. |
CAMPUS: A
Catalytic Multiecho Phase Unwrapping Scheme
Wei Feng1, Jaladhar Neelavalli1,
and E.M. Haacke1
1Wayne State University, Detroit,
MI, United States
Susceptibility weighted imaging (SWI)
utilizes phase information at long echo time
(TE). However, due to long TE, phase
aliasing inevitably occurs. For the purpose
of SWI, phase wraps can be removed by
conventional region growing methods or
homodyne filtering. Region growing phase
unwrapping methods are not always reliable
and conventional homodyne highpass filtering
induces undesired artifacts. We propose a
new pixel-wise catalytic multiecho phase
unwrapping scheme (CAMPUS) that is not based
on region growing and does not require
filtering. It is suited for multiecho
gradient echo imaging with short inter-echo
spacing, which is exploited to unwrap the
multiecho phase data.
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2667. |
On the impact
of regularization and kernel type on
SHARP-corrected GRE phase images
Ferdinand Schweser1,2, Karsten
Sommer1,3, Marie Atterbury1,4,
Andreas Deistung1, Berengar
Wendel Lehr1, and Jürgen R.
Reichenbach1
1Medical Physics Group, Dept. of
Diagnostic and Interventional Radiology 1,
Jena University Hospital, Jena, Germany, 2School
of Medicine, Friedrich Schiller University
of Jena, Jena, Germany,3School of
Physics and Astronomy, Friedrich Schiller
University of Jena, Jena, Germany, 4Dept.
of Physics, Brown University, Providence,
RI, United States
In this study we investigated the impact of
regularization and kernel type used with the
SHARP method based on a numerical brain
model. Furthermore, we present the smallest
possible kernel, which allows overcoming one
of the major pitfalls of SHARP, i.e. the
missing values at the edges of the brain.
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Traditional Posters
: Pulse Sequences, Reconstruction & Analysis
|
Click on
to view the
abstract pdf and click on
to view the pdf of the poster viewable in the poster hall.
|
Artifacts & Corrections: Imaging Near Metal
Thursday May 12th
Exhibition Hall |
13:30 - 15:30 |
2668. |
Investigations on Imaging
Near Metal with Combined 3D UTE-MAVRIC
Michael Carl1, Jiang Du2, and
Kevin Koch3
1Global Applied Science Laboratory, GE
Healthcare, San Diego, CA, United States, 2University
of California, San Diego, United States, 3Global
Applied Science Laboratory, GE Healthcare, Waukesha, WI,
United States
We investigated the potential combination of 3D UTE with
MAVRIC to image short T2 tissues surrounding orthopedic
implants with reduced susceptibility artifacts. Phantom
experiments were performed containing a stainless steel
plate immersed in agarose gel and imaged at 3T. Our
studies show that these two techniques may be combined
to harvest their respective advantages.
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2669. |
Predicting Pileup
Artifacts Around Magnetized Spheres in SWIFT Images
Robert O'Connell1, Steen Moeller2,
Curt Corum2, Djaudat Idiyatullin2,
and Michael Garwood2
1University of Minnesota, Minneapolis, MN,
United States, 2University
of Minnesota
Magnetic materials cause T2* shortening and frequency
shifts in MRI. With conventional techniques, magnetized
objects give rise to signal voids, whereas with SWIFT
the signal voids are surrounded by ‘pileup’ artifacts.
The pileup artifacts arise from the displaced signals
from off-resonance spins. By knowing how the signals are
displaced, it should be possible to return them to their
correct positions in image space, correcting the image
distortion. This work used an analytic method to derive
a predictive equation for the pileup artifact. The
equation was then verified through simulation and
experimental measurement of titanium balls.
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2670. |
MRI Artifacts due to
Ingestion of Iron Supplements
Jennifer Stoneburgh1, Ali Fatemi-Ardekani2,
Barry Smith3, and Michael D Noseworthy4,5
1Electrical and Computer Engineering,
McMaster University, Hamilton, Ontario, Canada, 2Medical
Physics, McMaster University, Hamilton, Ontario, Canada, 3Department
of Diagnostic Imaging, Children's Hospital of Eastern
Ontario, Ottawa, Ontario, Canada, 4Biomedical
Engineering; Electrical and Computer Engineering,
McMaster University, Hamilton, Ontario, Canada, 5Brain
Body Institute, St. Joseph's Healthcare, Hamilton,
Ontario, Canada
It is common MRI knowledge that iron causes rapid MR
signal dephasing and artifacts. Meanwhile, many people
take iron nutritional supplements for low iron status.
We describe here how ingestion of a standard "over the
counter" iron supplement, too soon before an MRI scan,
can result in artifacts. Based on steady state imaging
results and analytical measurement using a volume
magnetic susceptibility balance our results demonstrate
that patients should not ingest iron containing vitamin
supplements prior to an abdominal MRI scan.
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2671. |
3D MRI impression of metal
implant scan abutment in dental implantology
Andreas Johannes Hopfgartner1, Julian Boldt2,
Kurt Rottner2, Ernst Jürgen Richter2,
and Peter Michael Jakob3
1Experimental Physics 5, University of
Würzburg, Würzburg, Bavaria, Germany, 2Prosthodontics,
Dental School, University of Würzburg, Würzburg,
Bavaria, 3Experimental
Physics 5, University of Würzburg, Würzburg, Bavaria
Artifacts induced from dental alloys are potential
pitfall in dental MRT. Depending on the imaging sequence
and the material used, susceptibility as well as eddy
current artifacts are more or less distinct. In dental
implantology, a titanium implant is inserted into the
jaw bone. For virtual modeling of a fixed partial
denture, the orientation of the in situ implant must be
recorded along with the neighboring teeth, enabling the
dental technician to model a well-fitting restoration.
This is achieved by affixing a scan abutment with a
defined shape that can be detected by
pattern-recognition in the scan results. Despite the
presence of a metal body in immediate vicinity, the unit
consisting of PEEK screw, scan abutment and implant can
be measured in MRI and yield a dataset containing the
required information for further modeling of a fixed
partial denture by a dental technician. A method to
minimize and extrude disturbing metal artifacts is given
in this work.
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2672. |
Metal-induced artifacts in
computed tomography and magnetic resonance imaging:
comparison of biodegradable magnesium alloy versus titanium
and stainless steel control
Gustav Andreisek1, Thomas Frauenfelder1,
and Roger Luechinger2
1Department of Radiology, University Hospital
Zurich, Zurich, ZH, Switzerland, 2Institute
for Biomedical Engineering, University and ETH Zurich,
Zurich, ZH, Switzerland
Our aim was to evaluate metal artifacts induced by
biodegradable magnesium alloys – a new class of
degradable biomaterials - at CT and MR imaging at 1.5T
in comparison to standard titanium and stainless steel
controls. It was shown that biodegradable magnesium
alloys show less metal induced artifacts at CT and MR
imaging than the controls.
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Traditional Posters
: Pulse Sequences, Reconstruction & Analysis
|
Click on
to view the
abstract pdf and click on
to view the pdf of the poster viewable in the poster hall.
|
Artifacts & Motion: Correction
Monday May 9th
Exhibition Hall |
14:00 - 16:00 |
2673. |
Validation of DC
Self-Navigation for Breath-hold Period Identification in
Contrast-Enhanced 3D Radial Liver Perfusion Imaging
Debra E. Horng1,2, Ethan K. Brodsky1,2,
and Scott B. Reeder1,2
1Radiology, University of
Wisconsin-Madison, Madison, WI, United States, 2Medical
Physics, University of Wisconsin-Madison, Madison,
WI, United States
Quantitative perfusion imaging of liver tumors
requires acquisitions that occur over alternating
periods of breathing and breath-holding. Knowledge
of the time range when the liver is not moving is
necessary for accurate perfusion modeling. In this
work, we describe the use of DC phase and DC
magnitude signal measured every TR from a 3D-radial
contrast enhanced acquisition to identify
breath-holding periods. Results demonstrate
excellent agreement with respiratory bellows, which
were used as the reference standard.
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2674. |
In-vivo Tagged-MR
based Motion Correction in combined MR-PET
Se Young Chun1,2, Timothy G Reese2,3,
Bastien Guerin1,2, Ciprian Catana2,3,
and Georges El Fakhri1,2
1Division of Nuclear Medicine & Molecular
Imaging, Department of Radiology, Massachusetts
General Hospital, Boston, MA, United States, 2Radiology,
Harvard Medical School, Boston, MA, United States, 3Athinoula
A. Martinos Center for Biomedical Imaging,
Department of Radiology, Massachusetts General
Hospital, Boston, MA, United States
Motion artifacts in PET becomes a key problem
affecting image quality. Combined MR-PET provides a
new opportunity to improve PET image quality with
accurately estimated motion from simultaneously
acquired tagged MR without increased radiation dose.
Here we report progress in our in-vivo motion
correction study, showing results from a
free-breathing primate that demonstrates the
feasibility of PET motion correction in simultaneous
MR-PET. Our tagged MR based motion correction
methods significantly reduced motion artifacts and
noise as compared to no motion correction or gating.
They achieved image qualities comparable to those of
gating method with much longer (8x) acquisition.
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2675. |
Respiratory gating
with measurement time constraints applied to MRI with
continuously moving table
Matthias Honal1, and Tobias Baumann2
1Department of Radiology, Medical
Physics, University Medical Center Freiburg,
Freiburg, Germany, 2Department
of Radiology, University Medical Center Freiburg,
Germany
The application of respiratory gating for MRI with
continuously moving table is difficult. Due to the
variability of the breathing motion over time the
coverage of the complete k-space in the available
measurement time which is fixed by the table motion
cannot be guaranteed. In this study a variant of
respiratory gating is proposed that acquires the
required k-space data in a limited time as
consistently as possible with respect to motion.
Compared to acquisitions without motion correction
blurring artifacts are reduced thereby significantly
improving the diagnostic image quality.
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2676. |
Virtual Template
Registration for DCE-MRI Renography
Michael Hofer1, Gernot Reishofer2,
Stephen Keeling3, Michael Riccabona4,
Manuela Aschauer5, and Rudolf Stollberger6
1Institute of Medical Engineering,
University of Technology, Graz, Austria, 2Department
of Radiology, Medical University, Graz, Austria, 3Institute
for Mathematics and Scientific Computing, Karl
Franzens University Graz, Austria, 4Department
of Pediatric Radiology, Medical University Graz,
Austria, 5Department
of Radiology, Medical University Graz, Austria, 6Institute
of Medical Engineering, University of Technology
Graz, Austria
For the non-invasive assessment of renal perfusion
and functional parameters it is important to get
tissue specific data (e.g. renal cortex, renal
medulla). To overcome the problem of intensity
variations, an image registration procedure was
implemented which derives a virtual template image
series that keeps the underlying signal time course
intact. The algorithm is evaluated for a synthetic
kidney phantom and in vivo DCE-MRI data. It is seen
that the algorithm is robust against signal changes
due to the uptake of contrast media. Our results
indicate that for pixel-by-pixel evaluation of the
renal blood flow, registration is mandatory.
|
2677. |
Bias Correction for
Respiration Detection in Radial 3D Gradient-Echo Imaging
Robert Grimm1, Kai Tobias Block2,
Berthold Kiefer2, and Joachim Hornegger1,3
1Pattern Recognition Lab, Department of
Computer Science, University of Erlangen-Nuremberg,
Erlangen, Germany, 2Siemens
Healthcare MR, Erlangen, Germany, 3Erlangen
Graduate School in Advanced Optical Technologies
(SAOT)
Radial k-space sampling is a promising technique for
abdominal imaging due to the high motion robustness
and the embedded information on the respiration
phase. However, these self-gating signals are often
corrupted by high-frequency variations from an
angle-dependent bias, caused by inaccurate gradient
timings. Here, we present a novel filtering scheme
to estimate and correct the bias without
compromising temporal resolution. After correction,
the variance of the signal can be used to assess the
quality of the gating signal for different slices.
The approach is evaluated with volunteer data
acquired under irregular breathing patterns, and
results from gated reconstructions are shown.
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2678. |
Continuous Fat
Suppression during Respiratory Triggering
Alto Stemmer1, and Berthold Kiefer1
1Healthcare Sector, Siemens AG, Erlangen,
Germany
Slices acquired at the beginning of the acquisition
period of a respiratory triggered sequence may
suffer from insufficient fat suppression, if a
spectral selective saturation or inversion pulse is
used for fat suppression. The proposed reason is the
interruption of fat steady state during inspiration
while the sequence waits on the next trigger. In
this work the sequence of fat suppression modules is
continued in the trigger pauses. This maintains the
steady state and results in consistent fat
suppression in all slices.
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2679. |
Mouse cardiac MRI:
comparison of prospective synchronization using optical
and ECG signals with a retrospective technique
Raphaël Sablong1, Adrian Rengle1,
Audrey Pouzin1, and Olivier Beuf1
1CREATIS, CNRS UMR 5220, Inserm U1044,
INSA-Lyon, Université Lyon 1, Villeurbanne, France
An optical-based device designed to synchronize MRI
acquisition on small animals was developed using a
transmit-receive pair of optical fibers. The
suitability of the developed device was assessed on
ten mice and compared with ECG-gated and a
retrospective technique (IntraGate). MR images of
mice heart depict low visible motion artifacts with
all three investigated methods and no significant
SNR differences were found on images acquired or
processed with these different methods. However,
depending on device used, the triggering point does
not correspond to the same instant of the cardiac
cycle inducing a time shift between image series
acquired with the devices. Full fiber optical-based
signal derived from heart and respiratory motion was
suitable for prospective triggering for heart MR
imaging. The fiber optic device performed as well as
the ECG. The optical fiber-based device could be an
attractive alternative to commercially available
triggering devices for small animal MRI, when
retrospective method is inappropriate, in difficult
environments such as small volume available and fast
gradients switching.
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2680. |
Two degree-of-freedom
(DOF) MRI-compatible motion generation system for MRI
motion compensated algorithms evaluation
Slavisa Jovanovic1,2, Laure Rousselet1,2,
Lucas Albouy1,2, Pierre-André Vuissoz1,2,
Cédric Pasquier3,4, and Jacques
Felblinger1,2
1Imagerie Adaptative Diagnostique et
Interventionnelle, Nancy-Université, Nancy, France, 2U947,
INSERM, Nancy, France, 3CIT801,
INSERM, Nancy, France, 4CIC-IT,CHU-Nancy,
Nancy, France
Physiological motions can impair MR image quality by
generating artifacts. To overcome or decrease
artifact generation in MR images, synchronization or
image processing techniques taking into account
these motions must be employed. In order to validate
either new motion sensors or motion correction
algorithms in MRI environment before their use in
clinics, a reproducible motion generation system is
needed. Most of the solutions we find in literature
are limited to a small range of applications and
basic motion types. Within this framework, we
present a dynamic fully MRI-compatible motion
generation platform which was developed to evaluate
the influence of its generated motion on MR image
quality of phantoms and to assess image processing
algorithms used for motion artifacts removal. As an
initial test, we evaluate a motion correction
algorithm GRICS by imposing on its inputs a known 2D
motion generated with the developed mobile platform.
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2681. |
Motion Degradation in
3D µMRI of Trabecular Bone: Relevance to Quantitative
Analysis of Clinical Data
Yusuf A Bhagat1, Chamith S Rajapakse1,
Jeremy F Magland1, Michael J Wald1,
Hee K Song1, Mary B Leonard2,
and Felix W Wehrli1
1Laboratory for Structural NMR Imaging,
University of Pennsylvania, Philadelphia, PA, United
States, 2Nephrology,
The Children's Hospital of Philadelphia, United
States
Subtle subject movement during high-resolution µMR
scanning of trabecular bone (TB) causes blurring
rendering the data unreliable for quantitative
analysis. Images that were visually free of motion
artifacts from two groups of 10 healthy individuals
each differing in age were selected. We then applied
retrospectively derived translational motion
trajectories as phase shift to the k-space data of
these 20 subjects. Motion induction affected all TB
structural parameters. The significant difference in
structural parameter group means of the motion-free
images was lost upon motion degradation. The results
underscore the importance of subject movement and
its correction for TB structure analysis.
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2682. |
Characterisation of
Motion-Induced Field Distortions in Spectroscopic
Imaging With Prospective Motion Correction
Thomas Lange1, Daniel Nicolas Splitthoff1,
Maxim Zaitsev1, and Julian Maclaren1
1Department of Radiology, University
Medical Center Freiburg, Freiburg, Germany
Prospective motion correction based on an optical
tracking system in combination with retrospective
phase correction has recently been proposed for
spectroscopic imaging in the human brain and has
been validated for in-plane motion. In this work,
the method is assessed for through-plane motion,
focussing on the characterisation of motion-induced
field distortions in the VOI and evaluating the
potential for real-time shimming. Through-plane
motion causes stronger spectral degradation compared
to in-plane motion, particularly in the frontal
cortex close to the nasal cavities. For rotational
motion, the field distortions may contain large
second-order components, which are hard to correct
in real time.
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2683. |
A Practical Tracking
System to Avoid Motion Artifacts
Michael Herbst1, Julian Maclaren1,
Jan Gerrit Korvink2,3, and Maxim Zaitsev1
1Medical Physics, University Medical
Center Freiburg, Freiburg, Germany, 2Dept.
of Microsystems Engineering - IMTEK, University of
Freiburg, Freiburg, Germany, 3Freiburg
Institute of Advanced Studies (FRIAS), University of
Freiburg, Freiburg, Germany
Monitoring head motion is becoming a popular way to
prevent motion artifacts in brain imaging. However,
previously-described systems all have major
practical problems. We present a new method that
uses ‘optical-tracking-tape’, consisting of
bend-sensitive optical fibre. The tape is attached
to the head of the subject and used to identify
motion for real-time data rejection. In comparison
with other systems a major advantage of the tape is
the setup time (3minutes). No time consuming
calibration step is necessary and no direct line of
sight on the patients head is required, which makes
the system usable even with a enclosed headcoils.
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2684. |
Error evaluation and
data correction for the outlier signals in Q-ball
Imaging: comparison of orientation distribution function
Yen-Wei Cheng1, Ming-Choung Chou2,
Nai-Yu Cho3, Cheng-Yu Chen3,
and Hsiao-Wen Chung1
1Department of Electrical Engineering,
National Taiwan University, Taipei, Taiwan, 2Department
of Medical Imaging and Radiological Sciences,
Kaohsiung Medical University, Kaohsiung, Taiwan,3Department
of Radiology, Tri-Service General Hospital, Taipei,
Taiwan
Corrupted signals in diffusion-weighted images due
to hardware instability and physiological-related
fluctuations are observed in Q-ball imaging. We
proposed two suitable methods to restore the lost
signals in DWIs and reduce the ODF errors in this
study. The corrupted signals were replaced by its
repeated scan to get the gold standard. The mean ODF
errors between damaged QBI and gold standard QBI
before correction were 2.32%. However, the mean ODF
errors were reduced to 0.51% and 0.45% after
correction by symmetrical compensation method and
neighboring interpolation method. Therefore, we
concluded that neighboring interpolation was
suitable adjunct for QBI data processing.
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Traditional Posters
: Pulse Sequences, Reconstruction & Analysis
|
Click on
to view the
abstract pdf and click on
to view the pdf of the poster viewable in the poster hall.
|
Artifacts & Correction: B0 Estimation & Distortion
Correction
Tuesday May 10th
Exhibition Hall |
13:30 - 15:30 |
2685. |
Improved Frequency
Selective Fat Suppression using Tissue Susceptibility
Matched Pyrolytic Graphite Foams
Gary Chiaray Lee1,2, Caroline Jordan3,4,
Pamela Tiet2, Carlos Ruiz2,
Brian Hargreaves3, and Steven Conolly1,2
1Berkeley/UCSF Bioengineering Joint
Graduate Group, Berkeley, CA, United States, 2Bioengineering,
UC Berkeley, Berkeley, CA, United States, 3Radiology,
Stanford University, 4Bioengineering,
Stanford University
Magnetic susceptibility differences at air and
tissue boundaries produce B0 field inhomogeneities
near the skin and air cavities in the body, may
cause significant imaging artifacts, including
intravoxel dephasing, and distortion. These
artifacts can result in unreliable chemically
selective fat suppression, which exploit the 3.5 ppm
chemical shift between fat and water. We have
developed susceptibility matching pyrolytic
graphite-embedded foams that are safe for patient
use in MRI. Here we demonstrate significantly
improved in
vivo susceptibility
matching in the hand and neck, improved frequency
selective fat suppression in fat phantoms, and that
the foams do not adversely affect SNR.
|
2686. |
Accurate B0 mapping
with sparse TE stepping and k-space energy spectrum
analysis
Pei-Hsin Wu1, Nan-Kuei Chen2,
and Hsiao-Wen Chung1,3
1Department of Electrical Engineering,
National Taiwan University, Taipei, Taiwan, Taiwan, 2Brain
Imaging and Analysis Center, Duke University Medical
Center, Durham, NC, United States,3Institute
of Biomedical Electronics and Bioinformatics,
National Taiwan University, Taipei, Taiwan
We proposed an improved multi-TE approach for
accurate B0 mapping with phase unwrapping along the
TE dimension, using sparse TE spacing for shorter
acquisition time. The k-space energy spectrum
analysis method was used for an initial estimation
of the phase evolution as a function of TE,
following which the accurate phase values were
derived on a pixel-by-pixel basis from the multi-TE
data. Experimental results in the human brain using
four TE values with 9 msec spacing suggested that
our approach yielded accurate B0 maps in good
agreement with those obtained from 37 TE values at
0.752 msec spacing.
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2687. |
Off-Resonance Artifact
Correction with Convolution in k-space (ORACLE)
Wei Lin1, Feng Huang1, George
R Duensing1, and Arne Reykowski1
1Invivo Corporation, Philips Healthcare,
Gainesville, FL, United States
A rapid off-resonance artifact correction method is
proposed based on data convolution in k-space
(ORACLE). The acquired k-space is divided into
segments based on their readout time, and a
convolution kernel is applied to each segment to
render artifact-free data. ORACLE does not require a
separate B0 mapping scan, therefore reducing the
scan time and eliminating the need to align the B0
map with the actual imaging data. Phantom and in
vivo brain scans demonstrate the successful
application to radial, spiral and EPI datasets.
|
2688. |
Frequency Filtered
SENSE Shimming for B0 inhomogeneity detection
Daniel Nicolas Splitthoff1, and Maxim
Zaitsev1
1Dept. of Radiology, Medical Physics,
Unversity Medical Center Freiburg, Freiburg, Germany
Recently the generalised non-linear SENSE Shimming (SSH)
method was introduced, which can be used for
estimating B0 inhomogeneities. The approach uses a
reference image and tries to explain the time curve
of a Free Induction Decay (FID) based on a model
including relaxation and inhomogeneities. Due to the
usage of the FID the method was up to now restricted
to axial slices. We here introduce the concept of
frequency filtered FIDs which enables the method to
be used with an arbitrary slice orientation. Results
from an in vivo measurement are shown.
|
2689. |
Correcting B0 Induced
Signal Loss Using Echo Planar Imaging Reference Data
Dan Xu1, Joe K. Maier2, Kevin
F. King1, and Gaohong Wu2
1Applied Science Laboratory, GE
Healthcare, Waukesha, WI, United States, 2GE
Healthcare, Waukesha, WI, United States
B0 inhomogeneity can lead to significant signal loss
especially for slices far off isocenter and/or pulse
sequences with spectral spatial fat suppression
pulses. Collecting B0 map on a per-subject basis is
impractical because of the prolonged scan time. In
this paper, we propose a method to estimate and
correct the per-slice B0 offset using the freely
available echo planar imaging (EPI) reference data.
Spin echo EPI results on a phantom show that the
method can increase the signal for slices 15 cm away
from isocenter from 37% to over 75% as compared to
signal at the isocenter slice.
|
2690. |
Shim Navigators for
Accurate Detection of the B0 Magnetic Field
Inhomogeneities Using Reference MGE Images
Iulius Dragonu1, Daniel Nicolas
Splitthoff1, Nicoleta Baxan1,
Paul Freitag2, Jürgen Hennig1,
and Maxim Zaitsev1
1Dept. of Radiology, Medical Physics,
University Medical Center Freiburg, Freibug,
Baden-Wuerttemberg, Germany, 2Bruker
Biospin, Ettlingen, Baden-Wuerttemberg, Germany
The B0 magnetic field may change during the
experiment for several reasons: physiological
motion, such as breathing, subject motion and
hardware imperfections, such as passive shim element
heating. Changes in B0 homogeneities can lead to
unwanted signal fluctuations in EPI time course
acquisitions. As suggested previously, shim
navigators may allow the detection of magnetic field
evolution. It has been demonstrated that the phase
of a projection is not necessarily proportional to
the B0 field inhomogeneities along the direction of
that projection. In this work, we propose a method
for detection of zero- and first-order in plane
shims (f0, A11 and B11) based on shim navigators and
reference multi gradient echo images.
|
2691. |
R2* estimation in the
presence of fat and macroscopic B0 field variations
Diego Hernando1, Catherine DG Hines1,
and Scott B Reeder1,2
1Radiology, University of Wisconsin,
Madison, WI, United States, 2Medical
Physics, University of Wisconsin, Madison, WI,
United States
Quantitative, non-invasive estimation of R2* is an
important biomarker of hepatic iron overload.
Unfortunately, estimates of R2* may be confounded by
the presence of fat, as well as the signal dephasing
that occurs from macroscopic magnetic field
gradients caused by external susceptibility. In this
work, we propose a method that uses the complex
signal for estimation of R2*, correcting for the
presence of fat and macroscopic field variations.
Phantom and liver imaging results are shown to
illustrate the proposed method.
|
2692. |
Single-scan T2*
measurements with alternating compensation gradients for
linear background gradients
Yoonho Nam1, Hahnsung Kim1,
and Dong-Hyun Kim1
1Electrical & Electronic Engineering,
Yonsei University, Seoul, Korea, Republic of
Accurate measurement of T2* values, excluding the
effects of macroscopic field inhomogeneity, is
required in many applications. Macroscopic field
inhomogeneity induces additional signal decay and
leads to underestimated T2* values. Using
compensation gradients in slice-selection direction,
so called z-shim method, is an effective technique
to restore additional signal loss due to macroscopic
field inhomogeneity. Therefore, T2* measurements by
using these compensation gradients raise the
accuracy of T2* values. However, it requires
additional scan time for different compensation
gradients. In this study, we propose a
post-processing technique with alternating
compensation gradients in a single scan for accurate
T2* measurement.
|
2693. |
MR-based Field-of-View
Extension: Compensation of Field Imperfections
Jan Ole Blumhagen1,2, Ralf Ladebeck1,
Matthias Fenchel1, Jürgen Kampmeier1,
and Klaus Scheffler2
1Magnetic Resonance, Siemens Healthcare,
Erlangen, Bavaria, Germany, 2Division
of Radiological Physics, University of Basel
Hospital, Basel, Switzerland
Recently, the potential impact of a limited MR-based
field-of-view (FoV) in whole-body MR/PET attenuation
correction has been shown. In MR/PET the tissue
attenuation map can be calculated from the MR
images. However, the FoV restriction may cause a
truncation of the MR data for bigger patients and
therefore can bias the PET data reconstruction. In
this work, we will show exemplarily for 2DFT
spin-echo sequences a method that offers an extended
FoV in the transversal plane of up to 600mm using a
gradient field that compensates B0 inhomogeneities.
|
2694. |
MR-based Field-of-View
Extension: Gradient and B0 Correction Post-Processing
Jan Ole Blumhagen1,2, Ralf Ladebeck1,
Matthias Fenchel1, Jürgen Kampmeier1,
and Klaus Scheffler2
1Magnetic Resonance, Siemens Healthcare,
Erlangen, Bavaria, Germany, 2Division
of Radiological Physics, University of Basel
Hospital, Basel, Switzerland
Several studies demonstrated rectification of
static-field inhomogeneities inside a field-of-view
(FoV) of less than 500mm using phantom-based or
patient-based post-processing methods. However, in
whole-body MR/PET a distortion-free MR image using
an axial FoV up to 600mm would improve the human
attenuation correction. Furthermore, an extended FoV
can be useful in image-guided radio-surgery and
biopsy. In this work we will show exemplarily for 2D
spin-echo that significant distortion reduction
using post-processed B0 correction can be achieved
for an axial FoV up to 600mm.
|
2695. |
EPI Distortion
Correction Using Magnitude Difference Map
Hao Lv1, and Yong Chuan Lai1
1MR Engineering, GE Healthcare, Beijing,
Beijing, China, People's Republic of
In this study, a novel method using signal Magnitude
Difference map (MD map) is proposed to correct EPI
distortion. Compared with existing methods, it gives
more robust & effective correction while only
minimal sequence modification is needed.
|
2696. |
Dynamic unwarping of
multi echo EPI data
Eelke Visser1,2, Benedikt A. Poser3,
Markus Barth1,4, and Marcel P. Zwiers1,2
1Donders Institute for Brain, Cognition
and Behaviour, Radboud University Nijmegen,
Nijmegen, Netherlands, 2Department
of Cognitive Neuroscience, Radboud University
Nijmegen Medical Centre, Nijmegen, Netherlands, 3Department
of Medicine, Queen's Medical Center, Honolulu,
Hawaii, United States, 4Erwin
L. Hahn Institute for Magnetic Resonance Imaging,
University Duisburg-Essen, Essen, Germany
Inhomogeneities of the main magnetic field are known
to cause considerable geometric distortion of
EPI-acquired data. Accelerated acquisition reduces
the problem, but does not eliminate it. We calculate
field maps directly from the phase maps of the first
two echoes in a multi echo EPI acquisition and use
these to correct the residual distortions. The
resulting geometrical fidelity yields a significant
improvement in the co-registration to undistorted
data.
|
2697. |
First in vivo results
using decoupled projection based shimming
Daniel Nicolas Splitthoff1, and Maxim
Zaitsev1
1Dept. of Radiology, Medical Physics,
Unversity Medical Center Freiburg, Freiburg, Germany
It is well known that Echo Planar Imaging (EPI)
suffers strongly from geometric distortions caused
by B0 inhomogeneities. As a remedy it has for
example been suggested to correct for the
distortions in the image processing, based on
prescans. Nevertheless such approaches relay on the
assumption that the field inhomogeneities due not
change during the measurement, which is not
necessarily the case. We here present an improved
version of projection based real time linear shim
detection and correction, that takes into account
the cross talk between axes, when the orthogonality
is broken due to inhomogeneous magnetisation
distributions. The applicability of the method is
shown in in vivo correction of motion induced shim
changes.
|
2698. |
A Novel Correction
Method for Distortion Correction in EPI at Ultra High
Field MRI using PSF Mapping Technique
Se-Hong Oh1, Jun-Young Chung1,
Myung-Ho In2, Maxim Zaitsev3,
Oliver Speck2, Young-Bo Kim1,
and Zang-Hee Cho1
1Neuroscience Research Institute, Gachon
University of Medicine and Science, Incheon, Korea,
Republic of, 2Department
of Biomedical Magnetic Resonance, Institute for
Experimental Physics, Otto-von-Guericke University
Magdeburg, Magdeburg, Germany, 3Department
of Radiologic Research, Medical Physics, University
Hospital of Freiburg, Freiburg, Germany
Echo-planar imaging (EPI) is one of the fastest and
most widely used MRI pulse sequences in the field of
MRI. Compared to conventional imaging sequence, EPI
is more prone to a variety of artifacts. A prominent
EPI artifact is geometric distortion due to strong
magnetic field inhomogeneity and susceptibility.
Recently, a number of different approaches have been
proposed for correcting the distortion in EPI, one
of them is the point spread function (PSF) mapping
method. PSF distortion correction techniques are now
extensively used and are successful in the low field
strength MRI such as 1.5T or 3.0T. These techniques,
however, are still unable to correct distortions in
UHF MRI. Especially in UHF MR, EPI image has both
compressed and stretched geometric distortions
depending on the B1 field inhomogeneity and local
susceptibility. The shift map obtained in the
non-distortion (x-s) has more information over
compressed area. However, the ¡°PSF shift map¡±
obtained in the distortion plane or direction (x-y)
has more information in stretched area. Therefore,
to correct both compressed and stretched region,
shift map with more information is selectively
applied method is needed. To combine both method we
propose a PSF mapping method, which takes into
account both the distortion and the non-distortion
dimensional correction schemes, instead of
previously employed singular method where either
non-distortion or distortion dimensional correction
are used. By combining the distortion and
non-distortion dimensional correction scheme, we can
correct more accurately the geometric distortion
|
2699. |
View Angle Tilting in
Echo Planar Imaging for Distortion Correction
Sinyeob Ahn1, and Xiaoping Hu1
1Biomedical Engineering, Georgia
Institute of Technology and Emory University,
Atlanta, GA, United States
Distortion caused by field inhomogeneity is
prominent along the phase-encode (PE) direction in
echo planar imaging (EPI). This work describes a
method for correcting image distortion along the PE
direction using a view angle tilting (VAT) technique
in spin-echo EPI (SE-EPI). SE-EPI-VAT utilizes the
addition of gradient blips along the slice-select
direction, concurrently applied with the PE gradient
blips, producing an additional phase. This phase
offsets an unwanted phase by field inhomogeneity,
resulting in the correction of distortion. The
proposed method is simple and requires no
post-processing. It was validated by a phantom and
human brain imaging.
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Traditional Posters
: Pulse Sequences, Reconstruction & Analysis
|
Click on
to view the
abstract pdf and click on
to view the pdf of the poster viewable in the poster hall.
|
Denotsing
Wednesday May 11th
Exhibition Hall |
13:30 - 15:30 |
2700. |
Evaluation of image
quality improvement using wavelet denoising based on Stein's
Unbiased Risk Estimate (SURE)
Tao Zhang1, Peng Lai2, Shreyas
Vasanawala3, Robert Herfkens3,
Kedar Khare4, Luca Marinelli4,
Kevin F King5, and Anja Brau2
1Electrical Engineering, Stanford University,
Stanford, CA, United States, 2Applied
Science Laboratory, GE Healthcare, Menlo Park, CA,
United States, 3Radiology,
Stanford University, Stanford, CA, United States, 4GE
Global Research Center, Niskayuna, NY, United States, 5GE
Healthcare, Waukesha, WI, United States
Low SNR in MRI images can usually be found in cases with
parallel imaging and acquisitions with high spatial
resolution. Image denoising methods can increase SNR.
But some of them will introduce artifacts such as image
blurring. In this work, wavelet denosing based on
Stein’s Unbiased Risk Estimate (SURE) was evaluated on
various MRI applications. Comparisons on overall image
quality and image sharpness were carried out on these
applications. Based on the evaluation results from
radiologists, wavelet denoising based on SURE can
effectively increase SNR without introducing image
blurring.
|
2701. |
Controlled Denoising for
fMRI using Adaptive Overcomplete Dictionaries
Rajesh Venkataraman1, Steen Moeller2,
and Essa Yacoub2
1University of Minnesota, Minneapolis,
Minnesota, United States, 2University
of Minnesota
The abstract describes an algorithm to control the level
of denoising using knowledge of intrinsic noise and
parallel imaging g-factor for application towards
functional MRI
|
2702. |
A Simple Fast Method of
Gibbs Ringing Artifact and Noise Reduction with Edge
Enhancement Using Low-pass, Band-pass, and High-pass K-Space
Windowing Functions
Leping Zha1, Tsutomu Hoshino1, and
Yuichi Yamashita2
1Toshiba Medical Research Institute USA,
Inc., Vernon Hills, Illinois, United States, 2Toshiba
Medical Systems Corporation, Nasu, Tochigi, Japan
The existing Gibbs ringing reduction methods either
blurs out fine details in the images or tend to produce
piece-wise constant profile images of unnatural looking
for MR. A new simple, fast, and rather straightforward
method based on multiplying the k-space data with
low-pass, band-pass, and high-pass windowing functions,
and combining the results in image space simultaneously
and effectively reduces ringing artifacts and noise, and
enhance edges and fine details. The key components in
the algorithm include optimized matching windowing
functions and fast fuzzy edge extraction based on
band-pass spatial frequency selection.
|
2703. |
Three dimensional
restoration of cardiac magnetic resonance diffusion weighted
images based on sparse denoising
Lijun Bao1, Wanyu Liu2, Changwei
Hu1, Xiaobo Qu3, Shuhui Cai1,
and Zhong Chen1
1Department of Physics, Xiamen University,
Xiamen, Fujian, China, People's Republic of, 2Departments
of Automatic Measurement and Control, Harbin Institute
of Technology, Harbin, China, People's Republic of, 3Department
of Communication Engineering, Xiamen University, Xiamen,
Fujian, China, People's Republic of
There are spatial correlations between adjacent layers
in cardiac DWI sequence due to the organ consistency,
and each DWI contains repetitive structures. Therefore,
sparsity could arise from self-similarity of cardiac
DWIs. A 3D restoration method based on structure
adaptive sparse denoising (SAP-SPDN) is proposed.
Experimental results demonstrate that SAP-SPDN algorithm
has a good performance in denoising images with high
structural redundancy. It can achieve a trade-off
between image contrast and smoothness in denoising.
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|
|
Traditional Posters
: Pulse Sequences, Reconstruction & Analysis
|
Click on
to view the
abstract pdf and click on
to view the pdf of the poster viewable in the poster hall.
|
Fat & Water
Thursday May 12th
Exhibition Hall |
13:30 - 15:30 |
2704. |
Accelerated Water-Fat
Imaging Using Restricted Subspace Fieldmap Estimation
Samir D Sharma1, Houchun H Hu1,
and Krishna S Nayak1
1Electrical Engineering, University of
Southern California, Los Angeles, CA, United States
Water-fat separation based on multi-echo methods play an
important role in several clinical applications because
they reliably separate water and fat signals in the
presence of B0-field inhomogeneity. However, multi-echo
methods require longer scan times as compared to
single-echo imaging. An accelerated imaging technique is
desirable to reduce the length of these methods. This
work proposes a new approach for water-fat separation
from undersampled data acquisitions. The typical voxel-independent
model is generalized to consider estimation of water,
fat, field map, and R2* images directly from the
undersampled k-space data. Unlike previous works,
region-growing is not used for field map estimation.
|
2705. |
Joint Inhomogeneitiy
Estimation for Water-fat Separation with Multi-peak Fat
Modeling
Wenmiao Lu1, and Yi Lu2
1Electrical & Electronic Engineering, Nanyang
Technological University, Singapore, SG, Singapore, 2Electrical
and Computer Engineering, University of Illinois, Urbana
Champaign, Urbana, IL, United States
Key to the success of phase-sensitive water-fat
separation lies in robust estimation of field
inhomogeneities. This work describes a novel field map
estimation technique that systematically incorporates
field map smoothness and a priori likelihood of field
map values via belief propagation algorithm, which
perform joint estimation of field inhomogeneities across
2D image grid.
|
2706. |
Feasibility of water-fat
separation with diffusion weighted EPI
Ken-Pin Hwang1,2, and Jingfei Ma2
1Global Applied Science Laboratory, GE
Healthcare, Houston, TX, United States, 2Department
of Imaging Physics, University of Texas M.D. Anderson
Cancer Center, Houston, TX, United States
Fat suppression methods for EPI sequences are often
prone to inconsistency or loss of SNR. It is observed
that with parallel imaging, spatial shift of fat is
small relative to the variation in background field. In
this study, we evaluate the feasibility of applying
water-fat separation to an echo shifting EPI sequence.
Without diffusion weighting, successful water-fat
separation was achieved without modifications to the
algorithm. With diffusion weighting, water-fat
separation was possible when phase variations from the
coil sensitivity and the background field are first
corrected. These phase error maps can be estimated from
images acquired without diffusion weighting.
|
2707. |
Two-point Dixon imaging
with flexible echo times and a region growing-based
postprocessing algorithm
Jingfei Ma1
1Imaging Physics, University of Texas MD
Anderson Cancer Center, Houston, TX, United States
Water and fat separation using a two-point Dixon
technique is possible with images obtained at flexible
echo times. However, postprocessing has previously been
based on a statistical iterative process and involved a
specific fat signal model and empirical image
thresholding. In this study, we propose an alternative
strategy that includes a precalibration method for
determining the complex fat signal variation with echo
times and a fully automated region growing algorithm for
phase correction. Successful application of the proposed
strategy was demonstrated by phantom and in vivo images
obtained using a 3D dual-echo acquisition with flexible
echo times.
|
2708. |
A networked GPU
reconstructor within the clinical workflow for rapid fat
quantification.
Grzegorz Kowalik1,2, Jennifer Anne Steeden1,2,
David Atkinson2, and Vivek Muthurangu1
1Centre for Cardiovascular MR, UCL Institute
of Child Health, London, United Kingdom, 2Centre
for Medical Image Computing, UCL Department of Medical
Physics & Bioengineering, London, United Kingdom
Rapid imaging techniques and quantitative model fitting
often require significant computation time that hinders
clinical uptake. A good example is MRI fat water
separation techniques. This work aims to provide a GPU
accelerated image reconstruction platform to facilitate
computationally intensive algorithms. Flexible
networking architecture is used to accommodate
bidirectional communication between an external
reconstruction system and a scanner. The implementation
uses affordable GPU card to provide a real time
response. T2-IDEAL reconstruction, as an example of
time-consuming algorithm, is implemented and tested in
clinical environment. The adopted reconstruction
framework allows rapid reconstruction and immediate
assessment of the results.
|
2709. |
Combining phase images
from multi-channel RF coils using 3D phase offset maps
derived from a dual-echo scan
Simon Robinson1, Günter Grabner1,
Stephan Witoszynskyj1, and Siegfried Trattnig1
1Department of Radiology, Medical University
of Vienna, Vienna, Austria
We present a new, simple method for the combination of
phase images from multi-channel coils without the need
for a volume reference coil or prior processing such as
spatial filtering. The method is based on the
calculation and subtraction of 3D phase offsets for each
channel which are derived from a dual-echo scan. This
data comes either from the high resolution scan or is
acquired in a separate, fast, low resolution scan. This
second alternative is particularly computationally
efficient, can be applied to single-echo high resolution
data, and requires only a short (circa 30 s) additional
measurement. Both method variants give near-perfect
phase matching are compatible with parallel imaging.
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|
|
Traditional Posters
: Pulse Sequences, Reconstruction & Analysis
|
Click on
to view the
abstract pdf and click on
to view the pdf of the poster viewable in the poster hall.
|
Fat-Water MRI
Monday May 9th
Exhibition Hall |
14:00 - 16:00 |
2710. |
Fat Fraction Bias
Correction using Estimated T1 Values
Issac Yiqun Yang1, Curtis Nathan Wiens2,
Lanette Friesen-Waldner1, and Charles Andrew
McKenzie1,2
1Medical Biophysics, University of Western
Ontario, London, Ontario, Canada, 2Physics
and Astronomy, University of Western Ontario, London,
Ontario, Canada
Synopsis: Using small flip angles with IDEAL-SPGR
acquisitions reduces T1 bias
in fat fraction quantification at the cost of decreased
SNR. Since the exact T1 values
are unknown, bias correction using estimated T1s
was investigated. Simulations were used to determine
theoretical decrease in fat fraction bias using T1s
of various deviations. Measurement of T1 bias
in phantoms of various fat fractions demonstrated that
fat fraction bias can be reduced with estimated T1s,
even when those values are significantly different from
the true T1. This suggests that using
estimated T1s can be a simple but effective
means of fat fraction bias correction.
|
2711. |
Fat Water Classification
of Symmetrically Sampled Two-Point Dixon Images Using Biased
Partial Volume Effects
Thobias Romu1,2, Olof Dahlqvist Leinhard2,3,
Mikael F Forsgren3,4, Sven Almer4,
Nils Dahlström3,5, Stergios Kechagias3,
Fredrik Nyström3, Örjan Smedby2,3,
Peter Lundberg1,2, and Magnus Borga2,6
1Department of Radiation Physics, Center for
Surgery, Orthopedics and Oncology, Linköping University
Hospital, Linköping, Sweden, 2Center
for Medical Imaging Science and Visualization (CMIV),
Linköping University, Sweden, 3Department
of Medical and Health Sciences, Linköping University,
Sweden, 4Department
of Clinical and Experimental Medicine Faculty of Health
Science, Linköping University, Sweden, 5Department
of Radiology, Diagnostic Imaging Center, Linköping
University Hospital, Sweden, 6Department
of Biomedical Engineering, Linköping University, Sweden
Fat and water classification of symmetrically sampled
two-point Dixon images is required for automatic post
processing of the data after the phase sensitive
reconstruction. The problem was resolved by analyzing
the fat/water partial volume intensities which were
biased due to the mean intensity difference between the
two classes of signal. An evaluation was performed on
pre and post Gd-EOB-DTPA injection volumes of the liver
and whole-body datasets. A total of 905 tissue volumes
were included in the evaluation. Visual classification
was used as a golden standard. The result was a 100%
success rate.
|
2712. |
Simultaneous
Quantification of Fat Fraction and Fatty Acid Composition
Using MRI
Pernilla Peterson1, and Sven Månsson1
1Medical Radiation Physics, Lund University,
Malmö, Sweden
In this phantom study, a new reconstruction algorithm
based on multi-echo imaging is introduced which uses
theoretical knowledge of the chemical structure of fatty
acids (FA) to simultaneously quantify the fat fraction
(FF) and the FA composition. An iterative least squares
approach was used to estimate the number of double
bonds, number of methylene-interrupted double bonds,
chain length and water and fat signals. From these
estimates, FF and the fraction unsaturated FA (UF) were
calculated. Both FF and UF were successfully quantified.
These results clearly show that the investigated imaging
technique enables simultaneous quantification of FF and
FA composition.
|
2713. |
Assessment of Accuracy,
Repeatability, Reproducibility and Robustness of Fat
Quantification in a Water-Fat Phantom
Huanzhou Yu1, Catherine D.G. Hines2,
Ann Shimakawa1, Charles A McKenzie3,
Scott B Reeder4, and Jean H. Brittain5
1Global Applied Science Laboratory, GE
Healthcare, Menlo Park, CA, United States, 2Departments
of Radiology, Biomedical Engineering, University of
Wisconsin, Madison, Wisconsin, United States,3Department
of Medical Biophysics, University of Western Ontario,
London, Ontario, Canada, 4Departments
of Radiology, Medical Physics, Biomedical Engineering,
University of Wisconsin, Madison, WI, United States, 5Global
Applied Science Laboratory, GE Healthcare, Madison,
Wisconsin, United States
In this work, we assess the performance of an
IDEAL-based fat quantification method in a water-fat
phantom with fat-fractions ranging from 0 to 100%.
Assessment of the ground truth in phantoms allows
evaluation of accuracy. By repeating the scans on the
same scanner and different scanners, precision including
repeatability and reproducibility are also evaluated.
Finally, robustness is studied by changing a variety of
imaging parameters. We demonstrate that quantitative
IDEAL is highly accurate, repeatable, reproducible and
robust. It has potential to offer an accurate and
precise MR imaging method to measure fat-fraction in a
0~100% range, independent of imaging parameters.
|
2714. |
Mapping the Double Bonds
in Triglyceride
Mark Bydder1, Gavin Hamilton1,
Michael S Middleton1, and Claude B Sirlin1
1University of California San Diego, San
Diego, CA, United States
This study demonstrates the validity and feasibility of
using chemical shift imaging to map the degree of
saturation of triglycerides.
|
2715. |
Noise Performance of
Magnitude-based Water-Fat Separation is Sensitive to the
Echo Times
Huanzhou Yu1, Ann Shimakawa1,
Diego Hernando2, Catherine D.G. Hines3,
Charles A McKenzie4, Scott B Reeder5,
and Jean H. Brittain6
1Global Applied Science Laboratory, GE
Healthcare, Menlo Park, CA, United States, 2Departments
of Radiology, University of Wisconsin, Madison,
Wisconsin, United States, 3Departments
of Radiology, Biomedical Engineering, University of
Wisconsin, Madison, Wisconsin, United States, 4Department
of Medical Biophysics, University of Western Ontario,
London, Ontario, Canada,5Departments of
Radiology, Medical Physics, Biomedical Engineering,
University of Wisconsin, Madison, WI, United States, 6Global
Applied Science Laboratory, GE Healthcare, Madison,
Wisconsin, United States
Accurate fat-fraction quantification using chemical
shift based water-fat separation methods requires
correction of eddy-current induced phase errors that can
lead to substantial errors at low fat-fraction
estimates. The undesired phase modulation can be removed
by magnitude-signal based water-fat separation methods.
We show that noise performance of the magnitude-based
reconstruction is sensitive to echo times. Some
combinations of echo times may result in poor noise
performance, demonstrated by both simulations and
in-vivo scans. As a result, careful design of the
acquisition is required to avoid poor SNR that may lead
to inaccurate fat-fraction measurement when using
magnitude-based methods.
|
2716. |
Water fat opposed phase
(WFOP) sequence is a robust fat suppression technique under
the presence of B0 inhomogeneity in abdominal MRI at 3.0 T.
Koji Fujimoto1, Tomohissa Okada1,
Aki Kido1, Hiroshi Kusahara2,
Andrew Wheaton3, Mitsue Miyazaki3,
and Kaori Togashi1
1Diagnostic Imaging and Nueclear Medicine,
Kyoto university, Kyoto, Kyoto, Japan, 2Toshiba
Medical Systems Corporation, Otawara, Tochigi, Japan, 3Toshiba
Medical Research Institute, USA, OH, United States
Robustness of water fat opposed phase (WFOP) sequence to
B0/B1 inhomogeneity was evaluated at 3T quantitatively
and qualitatively by comparing with CHESS, and SPAIR.
Voxels with unsuppressed fat due to B0 inhomogeneity was
fewest for WFOP, and the degree was well presented by
inhomogeneity index. Image quality was rated best for
SPAIR due to effects of B1 field inhomogeneity in WFOP
and CHESS.
|
2717. |
Fully Automated
Quantification of Subcutaneous and Visceral Abdominal
Adipose Tissue using Water and Fat Acquisition and Graph
Cuts
Vitali Zagorodnov1, Sarayu Parimal2,
and Michael WL Chee2
1Nanyang Technological University, Singapore,
Singapore, Singapore, 2Duke-NUS
Graduate Medical School
We developed a fully automated algorithm for
quantification of visceral (VAT) and subcutaneous (SAT)
adipose tissue. Our algorithm is based on water and fat
acquisition (Dixon sequences), and improves on previous
work by utilizing fat-fraction images (for fat/non-fat
separation) and graph cuts (for separation of VAT and
SAT compartments). In our evaluation, the algorithm
achieved excellent correlations with manual
measurements, and outstanding reproducibility for both
SAT and VAT (coefficient of variation 1.5% and 2.3%
respectively).
|
2718. |
Image-based weighted B0
shimming using a fast multi-echo DIXON technique:
feasibility for abdominal imaging
Arjan Willem Simonetti1, Gabriele Beck1,
Hans Hoogduin2, Jeroen C.W. Siero3,
and Gwenael Herigault4
1MR CTO, Philips Healthcare, Best,
Netherlands, 2Brain
Division University Medical Center Utrecht, Utrecht,
Netherlands, 3Rudolf
Magnus Institute, University Medical Center Utrecht,
Utrecht, Netherlands, 4Clinical
Science, Philips Healthcare, Best, Netherlands
Clinically acceptable fat suppression is a key element
in abdominal MRI. B0 homogeneity plays an important role
in achieving fat suppression, but is not always optimal
using standard spectral-based B0 shimming approaches. We
propose a new method that combines mDIXON and
image-based weighted B0 shimming to achieve optimal fat
suppression. mDIXON allows to generate 3D B0 maps as
well as water and fat images which, when automatically
segmented, can be used to tailor the cost function
method employed in our shimming approach. Our results
show that this method improves significantly fat
suppression without impact on examination workflow and
duration.
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