ISMRM 24th Annual Meeting & Exhibition • 07-13 May 2016 • Singapore |
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Sunrise
Educational Session: Multiparametric MR for Cancer
Skill Level: Basic to Intermediate
Organizers: Guanshu Liu, Ph.D. & Mark D. Pagel, Ph.D.
Wednesday 11 May 2016
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Overview
MRI of cancer now involves many different sequence and protocol options.
This session will discuss diffusion, perfusion and spectroscopy as
multiparametric options. In addition, it will discuss the potential of
combining multiple methods in one paradigm to improve tumour detection
and monitoring.
Target Audience
This will benefit PhD and MD's who are interested in novel MRI methods
for detection and monitoring of cancer.
Educational Objectives
Upon completion of this course, participants should be able to:
- Understand the potential of
diffusion MRI for detection and monitoring of cancer;
- Understand the potential of
spectroscopy for detection and monitoring of cancer;
- Understand the potential of
perfusion MRI for detection and monitoring of cancer; and
- Understand the options for
using a multiparametric analysis to identify and monitor cancer.
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PROGRAM |
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Moderators: Jeong Min Lee, Taro
Takahara |
07:00
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Tumor Diagnosis with Diffusion - Permission Withheld
Nandita deSouza1
1The Institute of Cancer Research, London, UK
Diffusion-weighted MRI (DW-MRI) exploits the incoherent
motion of water molecules within tissues to generate
contrast. Many solid tumours exhibit restricted
diffusion of water molecules compared to many normal
tissues, leading to bright signal on diffusion-weighted
images and low values of Apparent Diffusion Coefficient
(ADC). Increase in necrosis/cell death after treatment
increases ADC which has been shown to be predictive of
response to chemotherapy in various tumour sites.
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07:30
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Multiparametric MRI Therapy Response in Bone 
Anwar R Padhani1
1Mount Vernon Cancer Centre, UK,
anwar.padhani@stricklandscanner.org.uk
Multimodal bone marrow imaging has the potential to
address the unmet need for a robust imaging methodology
that allows understanding of tumor biology, lesion
detection and therapy evaluation of advanced metastatic
disease. This means that there is a clearer
categorization of bone metastases response. Multimodal
bone imaging could be used for both clinical practice
and can be incorporated into clinical trials, generating
new biomarkers that in turn will require independent
validation.
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08:00
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Adjournment & Meet the
Teachers |
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The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for
Continuing Medical Education to provide continuing medical education for physicians. |