ISMRM 24th Annual Meeting & Exhibition • 07-13 May 2016 • Singapore |
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Sunrise Educational Session: CEST Imaging: Techniques & Challenges
Skill Level: Advanced
Organizers: Jenny T. Bencardino, M.D., Eric Y. Chang, M.D., Christine Chung, M.D., Ravinder R. Regatte, Ph.D., Philip Robinson, M.D. & Siegfried Trattnig, M.D.
Wednesday 11 May 2016
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Overview
This one-hour sunrise session will cover the added value of assessment of cartilage, disc and muscle using Chemical Exchange Saturation Transfer (CEST).
Target Audience
Radiologists and Physicists.
Educational Objectives
Upon completion of this course, participants should be able to:
- Describe current protocols and technical challenges in CEST imaging applied to the MSK system;
- Recognize the added value of CEST Imaging in evaluation of clinical and research patients; and
- Describe the current challenges for implementation of CEST method for clinical translation.
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PROGRAM |
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Moderator: Ravinder Reddy |
07:00
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CEST Imaging Techniques & Challenges 
Gil Navon1
1School of Chemistry, Tel Aviv University,
Tel Aviv, Israel
The following applications of CEST-MRI for endogenous
and exogenous diamagnetic agents will be reviewed:
glycoCEST, gagCEST, gluCEST, APT, crCEST, miCEST,
sialoCEST and mucCEST, glucoCEST and acidoCEST.
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07:25
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MSK Applications (Cartilage, Disc , Muscle)
Benjamin Schmitt1
1Magnetic Resonance, Siemens Healthcare
The two main applications for CEST in MSK are discussed
in this session. This will include an introduction to
glycosaminoglycan-dependent chemical exchange saturation
transfer (gagCEST) imaging as well as CEST imaging with
endogenous contrast in skeletal muscle. GagCEST imaging
has been very successfully used to assess loss of
proteoglycans in cartilage tissue and intervertebral
discs. The technical challenges of gagCEST, such as the
effect of field strength on signal will be explained,
and experimental considerations will be discussed.
Applications in skeletal muscle include CEST imaging of
lactate and creatine. Both metabolites are important
markers of energy metabolism and can be detected with
high spatial and temporal resolution using CEST.
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07:50
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Adjournment & Meet the
Teachers |
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The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for
Continuing Medical Education to provide continuing medical education for physicians. |