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			Weekend Course 
			ORGANIZERS: Jenny T. Bencardino, M.D., Eric Y. Chang, M.D., Christine Chung, M.D. & Philip Robinson, M.D.
 
 
			Sunday, 23 April 2017 
			
				| Room 316A | 08:15 - 12:15 | Moderators: | Neal Bangerter, Catherine Roberts |  
			Skill Level: Intermediate
 
 
			Slack Channel: #e_mskSession Number: WE22
 
 Overview
 The course will provide an in-depth discussion of state-of-the-art imaging techniques used musculoskeletal imaging from both technical and clinical perspectives. Imaging around metal, acceleration methods, diffusion imaging, multiparametric mapping, and spectroscopy will be reviewed. Each topic will contain a lecture focused on technical review as well as a lecture demonstrating clinical application.
 
 Target Audience
 Radiologists, Physicists and Clinical Care providers interested in reviewing current MR imaging techniques and their diagnostic applications.
 
 Educational Objectives
 Upon completion of this course, participants should be able to:
 
 -Recognize the importance of imaging around metal and need for acceleration techniques;
 -Apply and interpret diffusion imaging and multiparametric mapping in the clinical setting; and
 -Integrate proton MR spectroscopy for the characterization of tumors and tissues.
 
 
 
 
			
				| 08:15 
 | MR Imaging Around Metal: Technical Aspects  
					Clemens Bos 
					Orthopedic implants cause significant artifact in MRI. Here, we will make a classification of these artifacts. Then approaches to minimize the susceptibility related artifacts are desciribed, such as the use of "wide band" sequences, view angle tilting and multi-spectral imaging methods.  
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				| 08:50 
 | MR Imaging Around Metal: Clinical Applications  
					Kathryn Stevens 
					Metal implants are now commonplace in modern medicine. MRI evaluation of symptomatic patients with orthopedic hardware used to be severely limited by susceptibility artifact. However, recent advances in metal suppression techniques allow improved imaging around metal, making MRI effective for evaluation of patients with symptomatic implants, even at higher magnetic field strengths. This lecture will cover some of the common clinical applications of metal suppression MRI, particularly with respect to total hip and knee arthroplasties, and will also demonstrate the utility of metal suppression with respect to other implants and in the evaluation of patients with spinal hardware. 
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				| 09:25 
 | Acceleration Methods: Technical Aspects  
					Leslie Ying, Xiaojuan Li 
					MR quantitative imaging have been shown to be promising markers for detecting early degeneration and predicting disease progression in musculoskeletal (MSK) imaging due to its relatively independence of scanners/protocols. However, the long acquisition time and associated low resolution quantitative imaging have impeded their wide applications in clinical trials and practice. Recently compressed sensing and parallel imaging based acceleration methods have shown promise to address these challenges such that the quantitative imaging can be translated into clinical practice. Despite the extensive studies in other applications such as brain imaging, MR quantitative imaging in MSK has been overlooked. This course will teach some acceleration methods combining compressed sensing and parallel imaging and show their applications in MSK imaging.  
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				| 10:00 
 | Acceleration Methods: Clinical Applications  
					Richard Kijowski 
					Multiple different methods are now available which can been used to accelerate musculoskeletal MRI and improve the efficiency of MRI protocols for evaluating musculoskeletal diseases without compromising image quality or diagnostic performance.  These methods including the use of highly efficient spiral and radial k-space trajectories, 3T scanners, parallel imaging acceleration, isotropic resolution imaging, compressed sensing k-space under-sampling, and T2 shuffling.  
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				| 10:35 
 | Break & Meet the Teachers |  
				| 11:05 
 | MSK Applications of Diffusion Weighted Imaging: Technical Aspects  
					Jose Raya 
					The objective of this talk is to present a hands-on on the acquisition and processing of diffusion-weighted imaging tailored to MSK applications. In this presentation we will 
						explain how diffusion is measured and which is the meaning of the experimental parameters;
						
						discuss the different acquisition strategies for diffusion-weighted imaging; and learn how to optimize a diffusion protocol for a given
 
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				| 11:40 
 | MSK Applications of Diffusion Weighted Imaging: Clinical Applications  
					Won Hee Jee |  
				| 12:15 
 | Break & Meet the Teachers |  | 
	
		| 
			Translational Musculoskeletal Imaging: From Qualitative to QuantitativeWeekend Course
 
			ORGANIZERS: Jenny T. Bencardino, M.D., Eric Y. Chang, M.D., Christine Chung, M.D. & Philip Robinson, M.D.
 
 
			Sunday, 23 April 2017 
			
				| Room 316A | 13:15 - 16:05 | Moderators: | Neal Bangerter, Catherine Roberts |  
			Skill Level: Intermediate
 
 
			Slack Channel: #e_mskSession Number: WE22
 
 Overview
 The course will provide an in-depth discussion of state-of-the-art imaging techniques used musculoskeletal imaging from both technical and clinical perspectives. Imaging around metal, acceleration methods, diffusion imaging, multiparametric mapping, and spectroscopy will be reviewed. Each topic will contain a lecture focused on technical review as well as a lecture demonstrating clinical application.
 
 Target Audience
 Radiologists, Physicists and Clinical Care providers interested in reviewing current MR imaging techniques and their diagnostic applications.
 
 Educational Objectives
 Upon completion of this course, participants should be able to:
 
 -Recognize the importance of imaging around metal and need for acceleration techniques;
 -Apply and interpret diffusion imaging and multiparametric mapping in the clinical setting; and
 -Integrate proton MR spectroscopy for the characterization of tumors and tissues.
 
 
 
 
			
				| 13:15 
 | Quantitative MR Imaging: Technical Aspects - permission withheld 
					Yang Xia 
					Quantitative MRI in musculoskeletal tissues is challenging. Our technical ability to accurately measure and reliably interpret MRI parameters in musculoskeletal tissues can be influenced by the complexity of our specimens (human patient, animals, ex vivo specimen), instrumentation, experimental details, and data-analysis. This talk examines a number of these issues and their impact on the robustness of quantitative MRI, using the examples mainly from articular cartilage and its degradation process that leads to osteoarthritis. A brief comparison between articular cartilage and other musculoskeletal tissues (tendon, nasal cartilage, meniscus, and bone) will also be given. 
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				| 13:50 
 | Quantitative MR Imaging: Clinical Applications  
					Siegfried Trattnig 
					Quantitative techniques such T2/T2* imaging, sodium MRI and gagCEST help to analyze the composition of the connective tissues Results from quantitative techniques provide additional information and predictive markers for MSK structures and have the potential for the development of imaging biomarkers.
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				| 14:25 
 | Break & Meet the Teachers |  
				| 14:55 
 | MR Spectroscopy: Technical Aspects  
					Dimitrios Karampinos 
					Chemical shift encoding techniques can quantify chemical species content and investigate metabolic changes in physiological and diseased conditions of multiple musculoskeletal tissues, including skeletal muscle, bone marrow, intervertebral disc, cartilage and bone. The present lecture aims to provide an overview of the most important technical aspects when applying chemical shift encoding techniques, including single-voxel magnetic resonance spectroscopy, chemical shift imaging and chemical shift encoding-based water-fat separation techniques, for targeting lipids, creatine, macromolecules, choline and phosphorous metabolites in musculoskeletal tissues. 
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				| 15:30 
 | MR Spectroscopy: Clinical Applications - permission withheld 
					Miriam Bredella 
					MR spectroscopy is able to quantify intramyocellular lipids, intrahepatic lipids, and marrow adipose tissue in several clinical conditions. 
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				| 16:05 
 | Adjournment |    |