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Educational Course
Theranostics & Novel Molecular Probes |
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Theranostics & Novel Molecular Probes
Weekday Course
ORGANIZERS: Guanshu Liu, Arvind Pathak
Monday, 18 June 2018
| S02 |
08:15 - 10:15 |
Moderators: Robia Pautler, Xiaolei Song |
Skill Level: Intermediate to Advanced
Session Number: M-04
Overview
This course will provide a comprehensive overview of theranostic MR agents, including "smart" and "responsive" agents. The course will also cover precision diagnosis and treatment monitoring via theranostic approaches. Finally, a speaker from industry will summarize the translational potential of theranostic imaging.
Target Audience
Physicians, imaging scientists/engineers, technologists and other health professionals who are interested in MRI theranostics.
Educational Objectives
As a result of attending this course, participants should be able to:
-List recent developments in MRI theranostics;
-Describe structure and physical properties of preclinical and clinical MR contrast agents for precision diagnosis and treatment monitoring; and
-Discuss the potential and future of clinical translation of theranostic MRI.
08:15
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 MRI Capable Theranostic Agents
Hui Mao
New generation magnetic resonance imaging (MRI) contrast agents such as nanoparticles can be developed as theranostic agents which integrate the MRI contrast enhancing capability with therapeutic functions. The objective of this lecture is to give the audience an update of the recent developments in MRI enabled theranostics and stimulate the interests and new ideas to further advance the research and clinical translations of MRI enabled theranostics. The rational design of MRI capable theranostics agents, approaches for making the desired theranostic platforms, and MRI methods developed to enable MRI visualization of delivery processes will be discussed and presented with examples.
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08:55
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Treatment Monitoring Using Smart MRI Agents
Dmitri Artemov
In this presentation we will summarize the current state of molecular MRI using biologically active and/or targeted “smart” imaging agents to detect treatment response in several preclinical models of human diseases including cancer. Both methodological and biological aspects of the MR imaging strategies will be considered. We anticipate that by the end of the talk the audience should have improved understanding and appreciation of mechanisms and applications of novel state-of-the-art MRI imaging agents to various disease processes in preclinical models.
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09:35
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Potential & Requirements for Clinical Translation
John Waterton
This presentation discusses clinical translation of novel agents. Firstly, the conventional diagnostic drug development pathway is outlined. Then six unconventional pathways are introduced and illustrated with examples from MR and other diagnostic imaging modalities.
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10:15
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Adjournment & Meet the Teachers |
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| Back |
| The International Society for Magnetic Resonance in Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. |
