Sunrise Session
Cutting-Edge Primers on Preclinical Imaging: Neuroscience
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Session Topic: Educational Q&A: Preclinical
Session Sub-Topic: Cutting-Edge Primers on Preclinical Imaging: Neuroscience
Sunrise Session
ORGANIZERS: Catherine Hines, Damian Tyler, Neil Harris, Arvind Pathak
| Wednesday Parallel 1 Live Q&A | Wednesday, 12 August 2020, 15:15 - 16:00 UTC | Moderators: |
Skill Level: Intermediate
Session Number: S-M-03
Overview
This course will provide researchers a biology overview on animal models in neuroscience, cancer, inflammation, and cardiovascular medicine, followed by cutting-edge applications to study these disease areas.
Target Audience
Physicists beginning in vivo imaging, or needing a refresher on current techniques and animal models.
Educational Objectives
As a result of attending this course, participants should be able to:
- Define appropriate animal models for probing various diseases;
- Explain the underlying biology of these disease processes; and
- Identify appropriate techniques for answering biological questions in neuroscience, inflammation, infectious disease, oncology, and cardiovascular medicine.
| Primer on Transgenic Mouse Models for Neuropathologies
Piotr Walczak
Transgenic mice are now used in practically every branch of research. Studies on neuropathologies rely heavily on the use of transgenic mice including calcium indicator mice for in vivo imaging of neuronal function, knockout mice such as immune deficient models serving as excellent recipients of allo/xenografts. Multi-transgene models are also available with an example of immune deficient, myelin deficient rag2/shiverer mice used for studies on cell transplantation for the repair of white matter. Production of new transgenic lines are now cost effective and very fast, accelerating progress in biomedical research.
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| Structural & Functional Neuroimaging in Rodents
Jianyang Zhang
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