ISMRM & SMRT Virtual Conference • 08-14 August 2020

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Sunrise Session

Cutting-Edge Primers on Preclinical Imaging: Cardiac

Session Topic: Educational Q&A: Preclinical
Session Sub-Topic: Cutting-Edge Primers on Preclinical Imaging: Cardiac
Sunrise Session
ORGANIZERS: Catherine Hines, Damian Tyler, Neil Harris, Arvind Pathak
Wednesday Parallel 1 Live Q&A Wednesday, 12 August 202015:15 - 16:00 UTC Moderators: 
Skill Level: Intermediate

Session Number: S-Th-03

Overview
This course will provide researchers a biology overview on animal models in neuroscience, cancer, inflammation, and cardiovascular medicine, followed by cutting-edge applications to study these disease areas.

Target Audience
Physicists beginning in vivo imaging, or needing a refresher on current techniques and animal models.

Educational Objectives
As a result of attending this course, participants should be able to:
- Define appropriate animal models for probing various diseases;
- Explain the underlying biology of these disease processes; and
- Identify appropriate techniques for answering biological questions in neuroscience, inflammation, infectious disease, oncology, and cardiovascular medicine.

    Primer on Small & Large Animal Cardiac Models
Dara Kraitchman

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    Beyond Cardiac Function: Microstructure & Metabolism
Jürgen Schneider

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The cardiac microarchitecture is a key determinant of the relevant functions of the heart, including elec­trophysiological properties and mechanical activity, affecting both systemic blood flow and coronary perfusion. Thus, it also fundamentally determines metabolism of the heart muscle as a constant supply of substrates is crucial for the heart’s ability to continuously pump blood through the body. The aim of this presentation is to discuss two techniques beyond routinely applied assessments of cardiac function, namely the use of Diffusion Magnetic Resonance Imaging to investigate the microstructure of the heart and MR Spectroscopy to interrogate metabolic processes in the myocardium.