Junghun Cho1, Yuhan Ma2, Pascal Spincemaille3, Bruce Pike2,4, and Yi Wang1,3
1Biomedical Engineering, Cornell University, New York, NY, United States, 2McConnell Brain Imaging Centre, McGill University, Montreal, QC, Canada, 3Radiology, Weill Cornell Medical College, New York, NY, United States, 4Radiology, University of Calgary, Calgary, AB, Canada
1Biomedical Engineering, Cornell University, New York, NY, United States, 2McConnell Brain Imaging Centre, McGill University, Montreal, QC, Canada, 3Radiology, Weill Cornell Medical College, New York, NY, United States, 4Radiology, University of Calgary, Calgary, AB, Canada
Comparison between dual-gas
challenge calibrated-BOLD and QSM+qBOLD (QQ) model provided similar OEF and
CMRO2 in healthy subjects. QQ does not require a gas challenge, and reveal 14%
CMRO2 decrease with hypercapnia compared to baseline.
Baseline OEF, CBF, CMRO2 maps
between DGC and QQ in two healthy subjects. QQ CBF map is obtained by registering DGC CBF
map to QSM resolution. QQ showed less inter-subject
variation in OEF.
OEF, CBF, CMRO2 from QQ between
baseline (BL) and hypercapnia (HC) in two healthy subjects. Compared to BL, HC
shows lower OEF, higher CBF, slightly lower CRMO2.