Eberhard Daniel Pracht1, Philipp Ehses1, Hankyeol Lee2, Kamil Uludag2,3, and Tony Stoecker1,4
1German Center for Neurodegenerative Diseases, Bonn, Germany, 2Center for Neuroscience Imaging Research, Institute for Basic Science & Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Korea, Republic of, 3Techna Institute & Koerner Scientist in MR Imaging, University Health Network, Toronto, ON, Canada, 4Department of Physics and Astronomy, University of Bonn, Bonn, Germany
1German Center for Neurodegenerative Diseases, Bonn, Germany, 2Center for Neuroscience Imaging Research, Institute for Basic Science & Department of Biomedical Engineering, Sungkyunkwan University, Suwon, Korea, Republic of, 3Techna Institute & Koerner Scientist in MR Imaging, University Health Network, Toronto, ON, Canada, 4Department of Physics and Astronomy, University of Bonn, Bonn, Germany
We present an optimized, scan-time efficient multi-echo MP2RAGE sequence (ME-MP2RAGE) for improved brain segmentation at ultra-high field. The proposed method removes susceptibility induced image distortions along the readout direction.
Figure 2: ME-MP2RAGE acquisition
Left: Composite image 1 (odd_odd-even_even echo). Image distortions are significantly reduced compared to the MP2RAGE acquisition.
Right: A further decrease in image distortions is achieved using composite image 2 (odd_even - odd_even echoes).
Animated GIF images are depicted as well for better illustration of locally induced image distortions.
Figure1: MP2RAGE acquisition
Left: Difference image (odd -even echo). Image distortions induce signal enhancements/attenuations at tissue boundaries.
Right: Corresponding animated GIF illustrating the image distortions in greater detail.
