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Development of simultaneous calcium photometry and fMRI of the mouse brain
Shabnam Khorasani Gerdekoohi1, Hsu-Lei Lee1, Helena Hung-Yin Huang1, Pankaj Sah1, and Kai-Hsiang Chuang1,2
1Queensland Brain Institute, University of Queensland, Brisbane, Australia, 2Centre for Advanced Imaging, University of Queensland, Brisbane, Australia
We evaluated the feasibility of simultaneous optic fiber photometry of calcium reporter GCaMP6f and event-related fMRI in the mouse brain.
Fig.1 Visual evoked GCaMP6f response in mouse V1.
Fig.2 BOLD activation in the visual pathway detected by 1 and 0.3 s TR overlaid on the raw EPI.