1991
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Analysis of resting-state networks alterations of first-episode obsessive–compulsive disorder patients by independent component analysis
Junhong Liu1 and Jingliang Cheng1
1The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China
It’s considered that changes of abnormal resting-state networks might reveal the possible neural mechanism of OCD.
Figure 1. Three significant different masks of resting-state networks between obsessive-compulsive disorder patients and healthy controls. A) Posterior default-mode network (pDMN); B) Right frontoparietal network (RFP); C) Lateral visual network (lVN)
Figure 2. Compared with healthy controls, OCD patients exhibited increased functional connectivity (FC) in pDMN in the bilateral cuneus. The pDMN FC of OCD patients were higher than that of healthy controls in bilateral cuneus (T=3.822，P=0.005) in OCD patients. MNI coordinate (3, -75, 27), Brodmann's area 31, voxel 50.