Deep B. Gandhi1, Jonathan Dudley1, Ruchi Singh2, Jean A. Tkach1, Divya Sharma3, Amy Taylor2, Alexander G. Miethke2, and Jonathan R. Dillman1
1Imaging Research Center, Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States, 2Division of Hepatology, Gastroenterology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States, 3Department of Pathology and Laboratory Medicine, University of Cincinnati Medical Center, Cincinnati, OH, United States
1Imaging Research Center, Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States, 2Division of Hepatology, Gastroenterology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States, 3Department of Pathology and Laboratory Medicine, University of Cincinnati Medical Center, Cincinnati, OH, United States
Significant positive correlations were observed between GraSE and conventional liver T2 measurements for the weighted mean (r=0.80; p<0.01) and for individual
slices (r=0.72; p<0.01). No significant correlation was observed between
liver T2 measurements and histologic fibrosis stage.
Scatter
plots show the correlations between GraSE and conventional FSE T2 relaxation
times using the weighted mean (r=0.80; p<0.0001) for all slices for each
subject (n=31, left) and all individual slices (r=0.72; p<0.0001) for each
subject (n=181, right).
Box
plot on the left shows conventional T2 relaxation times for Metavir fibrosis
scores F0-F1 and F2-F4 (Mann Whitney U test p=0.75). Similarly, box plot on the
right shows GraSE T2 relaxation times for Metavir fibrosis scores F0-F1 and
F2-F4 (Mann Whitney U test p = 0.745)
