Sami Lehtovirta1,2, Ahti Kemppainen1,2, Marianne Haapea2,3, Jaro Karppinen2,4,5, Eveliina Lammentausta2,3, Vesa Koivukangas6, Eero Kyllönen7, Mika Nevalainen1,2,3, Anna-Maija Kauppila7, Victor Casula1,2, and Miika T. Nieminen1,2,3
1Research Unit of Medical Imaging, Physics and Technology, University of Oulu, Oulu, Finland, 2Medical Research Center, University of Oulu and Oulu University Hospital, Oulu, Finland, 3Department of Diagnostic Radiology, Oulu University Hospital, Oulu, Finland, 4Center for Life Course Health Research, University of Oulu, Oulu, Finland, 5Finnish Institute of Occupational Health, Oulu, Finland, 6Department of Surgery, Oulu University Hospital, Oulu, Finland, 7Department of Physical Medicine and Rehabilitation, Oulu University Hospital, Oulu, Finland
1Research Unit of Medical Imaging, Physics and Technology, University of Oulu, Oulu, Finland, 2Medical Research Center, University of Oulu and Oulu University Hospital, Oulu, Finland, 3Department of Diagnostic Radiology, Oulu University Hospital, Oulu, Finland, 4Center for Life Course Health Research, University of Oulu, Oulu, Finland, 5Finnish Institute of Occupational Health, Oulu, Finland, 6Department of Surgery, Oulu University Hospital, Oulu, Finland, 7Department of Physical Medicine and Rehabilitation, Oulu University Hospital, Oulu, Finland
Gastric
bypass surgery improves quality of cartilage in the lateral compartment of
femoral cartilage, reflected by significantly decreased T2 relaxation time, already
12 months after surgery.
Figure 1.
Sagittal T2-weighted image of tibiofemoral joint of a 57-year-old male from the
study group with a BMI of 32.2. Studied regions of interest are presented with
colors: central femur (blue), central tibia (red). Lighter color indicates deep
(d) and darker color superficial (s) cartilage. Bulk (b) cartilage contains
both superficial and deep component.
Figure 2. Estimated marginal
means with 95% confidence intervals of the T2 relaxation times at baseline and at
12-month follow-up from the repeated measures analysis of variance for the
study and control groups, adjusted for relative BMI change and
Kellgren-Lawrence grade. b=bulk, s=superficial, d=deep, c=central, F=femur.