Maria Concetta Morrone1, Alessandro Benedetto1, Mauro Costagli2, Michela Tosetti2, and Paola Binda1
1Department of Translational Research on New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy, 2IRCCS Stella Maris, Calambrone, Pisa, Italy
1Department of Translational Research on New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy, 2IRCCS Stella Maris, Calambrone, Pisa, Italy
Visual sensitivity
after a motor act oscillates over time. Using ultra-high field MR, we demonstrate
similar oscillations of V1 BOLD responses, together with functional coupling
between V1 and M1.
A. Event-related
design used to estimate BOLD responses to the visual stimulus
B. Black: perceptual
performance on the same task, measured outside the scanner on 7 subjects. Red:
BOLD response in central V1 (see also Figure 2B).
C. Results from a
representative subject, showing maps of BOLD responses to the keypress-only (discrimination
task) events and keypress+visual events (trial start), measured as GLM t-values.
D. BOLD response to
the keypress-only events averaged across all participants.
A-B. GLM estimates of
the BOLD response to keypress+visual events in the V1 subregion representing
the stimulus area. The response magnitude varies with the stimulus-to-keypress
delay from 70ms to 310ms, as summarized in panel B plotting the average across
subjects of the peak response at 6s.
C-D. Same as A-B for a
V1 far periphery (30-90 deg) representation. There is still a small BOLD
modulation (possibly reflecting contamination from a motor response), that is
not modulated as function of the stimulus-to-keypress delay.
