Boyu Zhang1, Xianfu Meng2, Yuwen Zhang1, Wenbo Bu2, and He Wang1,3
1Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China, 2School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, China, 3Human Phenome Institute, Fudan University, Shanghai, China
1Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China, 2School of Chemistry and Molecular Engineering, East China Normal University, Shanghai, China, 3Human Phenome Institute, Fudan University, Shanghai, China
We
propose an effective strategy that integrates T1 and MR temperature imaging for tracking photothermal
transducing agents and real-time temperature monitoring in
vivo. The time resolution is 20 seconds, and the
detection accuracy of temperature change is as low as 0.1K.
Figure3. Temperature
monitoring of tumors in: (A) intratumor
injection group, (B) intravenous injection group and (C) the control group.
Figure2. The T1 weighted images
before and after intratumorally injection of nanoPTAs (A) and intravenous injection
(B).