Augusto Lio M. Goncalves Filho1,2, Chanon Ngamsombat3, Stephen F. Cauley2, Wei Liu4, Daniel N. Splitthoff5, Wei-Ching Lo6, John E. Kirsch1, Pamela W. Schaefer1, Otto Rapalino1, Susie Y. Huang1,2, and John Conklin1,2
1Department of Radiology, Massachusetts General Hospital, Boston, MA, United States, 2Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, 3Department of Radiology, Siriraj Hospital, Bangkok, Thailand, 4Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, 5Siemens Healthcare GmbH, Erlangen, Germany, 6Siemens Medical Solutions Inc., Boston, MA, United States
1Department of Radiology, Massachusetts General Hospital, Boston, MA, United States, 2Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, 3Department of Radiology, Siriraj Hospital, Bangkok, Thailand, 4Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China, 5Siemens Healthcare GmbH, Erlangen, Germany, 6Siemens Medical Solutions Inc., Boston, MA, United States
Accelerated Wave-SPACE FLAIR is non-inferior to standard SPACE
FLAIR for detection of epileptogenic lesions on 3T MRI. Wave-SPACE FLAIR is up
to 4x faster than standard SPACE FLAIR, while being less susceptible to
flow-related artifacts and motion.
Figure 2. Representative
images showing a 36-year-old man with Left Mesial Temporal Sclerosis (arrow).
The signal and morphological abnormalities compatible with hippocampal
sclerosis are equally seen in both 3D Wave-CAIPI SPACE FLAIR (A) and in
the 3D standard SPACE FLAIR (B).
Figure 3. Representative
images showing a 32-year-old man with Tuberous Sclerosis presenting with
cortical tubers (arrows) and radial bands (arrowheads). The standard SPACE
FLAIR (A) sequence showed greater image degradation due to motion,
contrasting with the better performance of the Wave-CAIPI SPACE FLAIR (B) sequence
that was preferred over the standard sequence in the head-to-head comparison.
