Andrew T Curtis1 and Chad T Harris1
1Research and Development, Synaptive Medical, Toronto, ON, Canada
1Research and Development, Synaptive Medical, Toronto, ON, Canada
A bSSFP sequence with multiband saturation pulses was
implemented at 0.5T to assess ihMT contrast generation using the larger SAR and
B1+RMS limits. Results with B1+RMS as high as 15uT are promising with ihMT ratio
contrast of 12-16% in white matter.
Figure 1: Coronal and Axial views of MTR and ihMTR as a
function of pulse B1+RMS. Shaded regions
indicate ROIs used for MTR and ihMTR measurements in Table 2. Larger % ihMTR is
visible in the denser white matter tracts, as compared to MTR which is relatively
more homogeneous across all white matter.
Table 2: Observed and simulated MTR and ihMTR versus applied B1+RMS in two sample ROIs.