Casey P. Johnson1,2, Sampada Bhave1, Alexandra R. Armstrong1, and Ferenc Toth1
1Department of Veterinary Clinical Sciences, University of Minnesota, Saint Paul, MN, United States, 2Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States
1Department of Veterinary Clinical Sciences, University of Minnesota, Saint Paul, MN, United States, 2Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States
Quantitative
mapping of adiabatic T2ρ is sensitive in detecting ischemic injury to
the bone marrow, bone, and epiphyseal cartilage of the femoral head. This
technique may have advantages over and provide complementary information to T2
and T1ρ mapping.
Figure 1: Quantitative
T2, cwT1ρ,
αT1ρ,
and αT2ρ maps for one of the piglets. Also shown is subtracted
contrast-enhanced MRI, which shows a clear lack of perfusion to the ischemic
femoral head (asterisk), and the region of interest masks used to quantify the
regional relaxation time values. T2, cwT1ρ, and αT2ρ are all
noticeably increased in the secondary ossification center (SOC) of the ischemic
vs. contralateral-control femoral head. All four relaxation times are increased
in the epiphyseal cartilage.
Table 2: Region
of interest measurements for five pairs of ischemic and control femoral heads. Values
shown as mean ± standard deviation. * p<0.05.
