Ricardo Rios-Carrillo1, Ricardo Coronado-Leija2, Hiram Luna-Munguía1, Alonso Ramírez-Manzanares3, and Luis Concha1
1Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, Mexico, 2Radiology, New York University School of Medicine, New York, NY, United States, 3Centro de Investigación en Matemáticas, Guanajuato, Mexico
1Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, Mexico, 2Radiology, New York University School of Medicine, New York, NY, United States, 3Centro de Investigación en Matemáticas, Guanajuato, Mexico
Analysis of B-tensor encoding through QTE and DTD imaging is sensitive to white matter damage, and suggestive of specific diffusion signatures of axonal degeneration and inflammation.
Figure 2. QTE contrasts. A,C) Examples of denoised images with B-tensor encoding (b=2800 s/mm2) in a single slice from one representative animal per experimental condition. Yellow rectangles indicate enlarged areas in adjacent panels. B,D) QTE metrics for intact and injured optic nerves.
Figure 4. DTD imaging. A) and B) show examples of DTD representations obtained in regions as in Figure 2. C) and D) show the overlap of the DTDs for all voxels contained in the slice.