Charlotte E Buchanan1, Rebecca Noble2, Eleanor Cox1, Huda E Mahmoud2, Isma Kazmi2, Benjamin Prestwich1, Nicholas Selby2, Maarten Taal2, and Susan T Francis1
1Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom, 2Centre for Kidney Research and Innovation, University of Nottingham, Derby, United Kingdom
1Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom, 2Centre for Kidney Research and Innovation, University of Nottingham, Derby, United Kingdom
We assessed changes in renal MR measures to predict
progression of CKD. Baseline measures of T1 and perfusion were different
between progressors and stable patients, this could predict progression. Over time T1 and volume changed more in progressors which could be used to monitor progression
Figure 1: A)
Longitudinal relaxation time (T1) for the CKD cohort at baseline
divided into ‘stable’ (n=13) and ‘progressors’ (n=9), B) Percentage change in T1
at Year 1 and Year 2 as compared to baseline for the ‘stable’ and ‘progressor’
group, C) Individual subjects shown at baseline, Year 1 and Year 2 with the ‘stable’
group shown in black and ‘progressors’ in red. [CM diff = corticomedulllary
difference]
Figure 2: A) Renal cortex perfusion for the CKD cohort at baseline divided
into ‘stable’ (n=13) and ‘progressors’ (n=9), B) Percentage change in perfusion
at Year 1 and Year 2 as compared to baseline for the ‘stable’ and ‘progressor’
group. C) Individual subjects shown at baseline, Year 1 and Year 2 with the ‘stable’
group shown in black and ‘progressors’ in red.
