Filip Klimeš1,2, Andreas Voskrebenzev1,2, Lea Behrendt1,2, Marcel Gutberlet1,2, Gesa Helen Pöhler1,2, Till Frederik Kaireit1,2, Cristian Crisosto1,2, Frank Wacker1,2, and Jens Vogel-Claussen1,2
1Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany, 2Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Centre for Lung Research (DZL), Hannover, Germany
1Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany, 2Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Centre for Lung Research (DZL), Hannover, Germany
The influence of chosen target
volume for registration on PREFUL-derived parameters was assessed. Although small significant variations
were observed a high absolute agreement of all functional parameters was found indenpedent
on the chosen target volume.
Figure 1: Comparison of ventilation parameters of a 67-years-old COPD patient (left column – registration to expiration, middle column – registration to
middle respiratory state, right column – registration towards inspiration).
Note similar pattern of hypoventilated areas in RVent maps and areas with
abnormal ventilation dynamics in CC maps for all three different registrations.
RVent / CC: 0.22 ml/ml / 0.54 for registration towards expiration, 0.21 ml/ml /
0.59 for registration towards middle respiratory state and 0.27ml/ml / 0.55 for registration towards
inspiration.
Figure 2: Comparison of perfusion parameters (QN and QDP) of a 75-years-old CTEPH patient in representative dorsal
slice (left column – registration to expiration, middle column – registration
to middle respiratory state, right column – registration towards inspiration).
Note hypoperfused areas in the left lung, which are marked as defect areas in
perfusion defect percentage map. QN / QDP: 2.7% /
47.7%
for registration towards expiration, 2.0% / 57.6% for registration towards
middle respiratory state and 1.9% / 57.8% for registration towards
inspiration.
