Darren Hsu1, Fei Tan2, Michael Lustig3, and Peder E. Z. Larson4
1Department of Computer Science, University of California, Berkeley, Berkeley, CA, United States, 2Department of Bioengineering, University of California, Berkeley - University of California, San Francisco, San Francisco, CA, United States, 3Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA, United States, 4Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States
1Department of Computer Science, University of California, Berkeley, Berkeley, CA, United States, 2Department of Bioengineering, University of California, Berkeley - University of California, San Francisco, San Francisco, CA, United States, 3Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA, United States, 4Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States
To analyze localized respiratory function, biomarker metrics are extracted from 3D UTE phase resolved MR images using signal intensity based methods. Visualizations are then generated to depict the rate and velocity at which lung tissue expands from full inspiration to full expiration.
Coronal plane slice of a healthy volunteer with the Time to Peak (TTP) and Full Width Half Max (FWHM) biomarker on the left and right, respectively. The scans were repeated twice for reproducibility, with the first and second rows of the image corresponding to repeated scans of the volunteer. For the TTP biomarker, a value of five is to be expected as the fifth phase corresponds to exhalation, representing the highest signal intensity value. For the FWHM biomarker, a value of six is expected, as it would capture the phases before and after full exhalation.
Sagittal plane slice of a healthy volunteer with the Time to Peak (TTP) and Full Width Half Max (FWHM) biomarker on the left and right, respectively. The scans were repeated twice for reproducibility, with the first and second rows of the image corresponding to repeated scans of the volunteer. The results of the sagittal place slice support the findings of the coronal plane slice visualization.
