0614
Accurate and precise myocardial T1 and T2 mapping in a single breath-hold with multi-parametric SASHA
Kelvin Chow1, Genevieve Hayes2, Jacqueline Flewitt2, Patricia Feuchter2, Carmen Lydell2, Andrew Howarth2, Joseph Pagano3, Richard Thompson4, Peter Kellman5, and James White2
1Cardiovascular MR R&D, Siemens Medical Solutions USA, Inc., Chicago, IL, United States, 2Stephenson Cardiac Imaging Centre, University of Calgary, Calgary, AB, Canada, 3Division of Pediatric Cardiology, University of Alberta, Edmonton, AB, Canada, 4Biomedical Engineering, University of Alberta, Edmonton, AB, Canada, 5National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, United States
mSASHA is novel multi-parametric cardiac mapping sequence that provides T1 and T2 maps in a single breath-hold.  mSASHA was validated in phantoms with an average -0.7% T1 error and -1.3% T2 error.  In 10 volunteers at 3T, mSASHA had similar T1 and Tprecision compared to MOLLI, SASHA, and T2p-bSSFP.
Fig. 4. T1 and T2 maps with mSASHA, SASHA, MOLLI, and linear T2p-bSSFP in a healthy volunteer at 3T.
Fig. 1. Sequence diagram for multi-parametric SASHA. A series of images are acquired without magnetization preparation, with saturation-recovery preparation, and with both saturation-recovery and T2-preparation.