Jochen Keupp1, Petra J. v. Houdt2, Jakob Meineke1, Paul de Bruin3, Johannes M. Peeters3, Leon ter Beek4, and Mariya Doneva1
1Philips Research, Hamburg, Germany, 2Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, Netherlands, 3Philips Healthcare, Best, Netherlands, 4Department of Medical Physics, The Netherlands Cancer Institute, Amsterdam, Netherlands
1Philips Research, Hamburg, Germany, 2Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, Netherlands, 3Philips Healthcare, Best, Netherlands, 4Department of Medical Physics, The Netherlands Cancer Institute, Amsterdam, Netherlands
T2-maps may
provide objective results for diagnosis/therapy in prostate cancer (PCa) but need a long acquisition. 4min compressed
sensing T2-mapping was tested in a PCa patient using irregular sampling and low rank/sparsity
constraints with good results comparing to regular k-t T2-mapping.
Figure 1: Fast-spin echo imaging and T2-mapping results in a prostate cancer
patient. (A) Clinical image, transverse T2w. (B,D) Results from k-t T2 mapping,
(C,E) from T2-CSXD. (B,C) Show single
echo images at TE=128ms, (D,E) show the resulting T2 maps (grey scale 0...250ms)
from fitting all echoes images.
Figure 2: Optimization of T2-CSXD in terms of ΔT2[%] (relative deviation T2-CSXD
versus k-t T2) and precision (SD: relative standard deviation). Data for ROIs
within the prostate with low mean T2-values (A,B: 83ms) and mid-range T2-values
(C,D: 145ms) are shown.
