0631
Simultaneous pure spin-echo and gradient-echo BOLD fMRI using Echo Planar Time-resolved Imaging (EPTI) for mapping laminar fMRI responses
Fuyixue Wang1,2, Zijing Dong1,3, Lawrence L. Wald1,2, Jonathan Polimeni1,2, and Kawin Setsompop4,5
1Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 2Harvard-MIT Health Sciences and Technology, MIT, Cambridge, MA, United States, 3Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA, United States, 4Department of Radiology, Stanford University, Stanford, CA, United States, 5Department of Electrical Engineering, Stanford University, Stanford, CA, United States
The proposed method SE-EPTI provides pure SE, GE and SE images with different ETLs simultaneously. We demonstrated at 7T that the pure SE can significantly reduce the draining-vein-effect, and less T2’-contamination was introduced with shorter ETLs.
Figure 2. The activation maps in z-scores from the pure SE, GEs and the extracted conventional SE-EPI images provided by EPTI in a single acquisition.
Figure 5. Preliminary fMRI data of echo-train-shifted SE-EPTI: (a) the activation map in z-score compared with symmetric EPTI; (b) the cortical depth profiles of the percent signal change from GE, 6-shot SE EPI and pure SE provided by echo-train-shifted SE-EPTI.