Hsin-Ju Lee1,2, Pu-Yeh Wu1, Hankyeol Lee3, Kamil Uludag3,4, Hsiang-Yu Yu5,6,7, Cheng-Chia Lee6,7,8, Chien-Chen Chou5,6, Chien Chen5,6, Wen-Jui Kuo7,9, and Fa-Hsuan Lin1,2,10
1Physical Sciences Platform, Sunnybrook Research Institute, Toronto, ON, Canada, 2Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada, 3Center for Neuroscience Imaging Research, Institute for Basic Science, Suwon, Korea, Republic of, 4Techna Institute & Koerner Scientist in MR Imaging,, Joint Department of Medical Imaging and Krembil Brain Institute, University Health Network, Toronto, ON, Canada, 5Department of Epilepsy, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, 6School of Medicine, National Yang-Ming University, Taipei, Taiwan, 7Brain Research Center, National Yang-Ming University, Taipei, Taiwan, 8Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, 9Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan, 10Department of Neuroscience and Biomedical Engineering, Aalto University, Espoo, Finland
1Physical Sciences Platform, Sunnybrook Research Institute, Toronto, ON, Canada, 2Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada, 3Center for Neuroscience Imaging Research, Institute for Basic Science, Suwon, Korea, Republic of, 4Techna Institute & Koerner Scientist in MR Imaging,, Joint Department of Medical Imaging and Krembil Brain Institute, University Health Network, Toronto, ON, Canada, 5Department of Epilepsy, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, 6School of Medicine, National Yang-Ming University, Taipei, Taiwan, 7Brain Research Center, National Yang-Ming University, Taipei, Taiwan, 8Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan, 9Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan, 10Department of Neuroscience and Biomedical Engineering, Aalto University, Espoo, Finland
We found that the fMRI signals in the auditory cortex were positively and negatively correlated with neural oscillations in the gamma and alpha/beta bands, respectively, during music listening. These correlations were highest at the intermediate cortical depth.
Figure
4. Color-coded Z-scores of the correlation
between fMRI signal and frequency-specific (8 Hz to 150 Hz) neural oscillatory
response at deep (gray-white matter boundary; normalized depth n.d. = 0.1),
intermediate (n.d. = 0.5), and superficial (n.d. = 0.9) depths at the core (top
row) and non-core (middle row) auditory cortex (pink areas on the brain) and
their differences (bottom row) derived from 7T (left column) and 3T (right
column) data.
Figure 3. Z-scores of the correlation between fMRI signal and frequency-specific (8 Hz to 150 Hz) neural oscillatory response at deep (gray-white matter boundary; normalized depth n.d. = 0.1), intermediate (n.d. = 0.5), and superficial (n.d. = 0.9) depths in the auditory cortex (the pink area on the brain) at right (A, C) and left (B) hemispheres using 7T (A, B) and 3T (C) data. Significant differences between deep/superficial and intermediate depths have a transparent reddish/bluish background.