Chathura Kumaragamage1, Peter B Brown1, Scott McIntyre1, Terence W Nixon1, Henk M De Feyter1, and Robin A de Graaf1
1Department of Radiology and Biomedical Imaging, Magnetic Resonance Research Center, Yale University, New Haven, CT, United States
1Department of Radiology and Biomedical Imaging, Magnetic Resonance Research Center, Yale University, New Haven, CT, United States
An
asymmetric GOIA pulse was developed with TW = 1.7% by combining hyperbolic
secant, and hyperbolic tangent modulations (Tp = 6.66 ms, BW = 20
kHz). Utilizing a 4-pulse OVS method, highly selective B1 and T1-independent
OVS can be achieved in vivo.
Figure
3. (A-C) Phantom results illustrating localization performance of the RF pulses
compared, selective for a 7 cm slab, and (D) illustrates traces along the X
direction for the cases with a zoomed cut out
illustrating the transition profile obtained for the three pulses. Excellent
signal suppression throughout the slice (Mz/M0 < 0.02)
and minimal perturbation outside the inversion band is seen for all pulses.
Figure
5. An in vivo MRSI data acquired (TE/TR = 30 ms/2000 ms, 8.2 min acquisition time, 10 x 10 mm2
grid from a 5 mm axial slab) utilizing ECLIPSE localization. The anatomical
image illustrates six-voxel positions on the left, and 9 voxel locations on the
right, corresponding to illustrated spectra. The ellipse in red color
illustrates the water ROI selected with ECLIPSE, and the blue ellipse
corresponds to the lipid ROI due to chemical shift ~1.6 mm smaller in radius along
the x-direction.
