Abdul Wahed Kajabi1,2,3, Stefan Zbyn1,3, Cyrus M. Nouraee1, Kai D. Ludwig1,3, Casey P. Johnson1,4, Steen Moeller1, Mark A. Tompkins5, Bradley J. Nelson5, Gregory J. Metzger1, Cathy S. Carlson4, and Jutta M. Ellermann1,3
1Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 2Research Unit of Medical Imaging, Physics and Technology, University of Oulu, Oulu, Finland, 3Department of Radiology, University of Minnesota, Minneapolis, MN, United States, 4Department of Veterinary Clinical Sciences, University of Minnesota, Minneapolis, MN, United States, 5Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN, United States
1Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 2Research Unit of Medical Imaging, Physics and Technology, University of Oulu, Oulu, Finland, 3Department of Radiology, University of Minnesota, Minneapolis, MN, United States, 4Department of Veterinary Clinical Sciences, University of Minnesota, Minneapolis, MN, United States, 5Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN, United States
Diffusion-weighted MRI allows
quantitative evaluation of juvenile
osteochondritis dissecans of the knee, can differentiate between healed
and not yet healed lesions, and can distinguish between the operative and
nonoperative treatment groups.
Figure 2. A 15-year old boy with stage III JOCD
lesion. (A) The first echo of the T2*-weighted images showing lesion region
(arrow). (B) The corresponding color-coded apparent diffusion coefficient (ADC)
map. The zoomed in box of the lesion and control regions in (A) depicts the
evaluated regions: progeny lesion (light green), interface (red), adjacent
parent bone (cyan), distant parent bone (magenta), adjacent cartilage (dark
blue), contralateral cartilage (yellow), and contralateral parent bone (dark
green).
Figure 3. The average
of the median ADC values measured in ROIs at JOCD stage I (n=7), stage II
(n=20), stage III (n=12) and stage IV (n=7). Decreased ADC values
were observed in patients with JOCD stage IV compared to JOCD stages I-III in
the interface, lesion and adjacent parent bone.
