SHUANG MENG1, Ailian Liu1, Lihua Chen1, Qinhe Zhang1, Qingwei Song1, and Yunsong Liu1
1The First Affiliated Hospital of Dalian Medical University, Dalian, China
1The First Affiliated Hospital of Dalian Medical University, Dalian, China
In this study, we evaluated the diagnostic
performances of Tofts model (TM) in assessing oligometastatic prostate cancer
(PCa). The results showed that transfer constant (Ktrans) can differentiate the
diagnosis oligometastatic and widely metastasis PCa ((OR (95CI)＜0.001,95%
CI:0.000-0,028), and the AUC (95CI)= 0.77). Ktrans combined with clinical
characteristics (such as age and prostate specific antigen (PSA)) had the higher
diagnostic efficiency (AUC (95CI)=0.958). Therefore Ktrans has the potential to
assess the aggressiveness of PCa . And Ktrans combined age and PSA maybe have the
higher diagnostic efficiency for oligometastatic and widely metastasis PCa
Figure 1 A 60-year-old male with localized lesions PCa.ROI was manually placed on the local
lesion of DCE map (A). The Ktrans, Kep and Ve maps of TM were shown(B-D).
Figure
2.ROC curves show performangces of Ktrans
individually and combination of age and PSA to
differentiate between oligometastatic and
widely metastasis PCa.