Banu Sacli-Bilmez1, Ayca Ersen Danyeli2,3, Murat Şakir Ekşi4, Kübra Tan5, Ozge Can6, Cengiz Yakicier7, M.Necmettin Pamir3,4, Alp Dincer3,8, Koray Özduman3,4, and Esin Ozturk-Isik1
1Institute of Biomedical Engineering, Bogazici University, Istanbul, Turkey, 2Department of Medical Pathology, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey, 3Center for Neuroradiological Applications and Reseach, Acıbadem Mehmet Ali Aydinlar University, Istanbul, Turkey, 4Department of Neurosurgery, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey, 5Health Institutes of Turkey, Istanbul, Turkey, 6Department of Medical Engineering, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey, 7Department of Molecular Biology and Genetics, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey, 8Department of Radiology, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey
1Institute of Biomedical Engineering, Bogazici University, Istanbul, Turkey, 2Department of Medical Pathology, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey, 3Center for Neuroradiological Applications and Reseach, Acıbadem Mehmet Ali Aydinlar University, Istanbul, Turkey, 4Department of Neurosurgery, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey, 5Health Institutes of Turkey, Istanbul, Turkey, 6Department of Medical Engineering, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey, 7Department of Molecular Biology and Genetics, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey, 8Department of Radiology, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey
Higher Glyc and
Ins+Glyc levels in aggressive meningiomas, and higher Glu, GPC, and Glx levels
in hyperostotic tumors as determined by noninvasive, clinical, single-voxel
1H-MRS can provide clinically useful clues on tumor biology in meningiomas.
Figure 1. MR spectroscopic data with some of the LCModel
results of grade I (a) and grade II (b) meningioma.
Table 1. The metabolite peak intensity differences
between different grades of meningiomas
and the p-values of a Mann-Whitney U
test.