Intra-patient comparison of 3D and 2D MRE techniques for assessment of liver fibrosis
Roberta Catania1, Amir A. Borhani1, Camila Lopes Vendrami1, Roger C Grimm2, Bradley D. Bolster3, and Frank Miller1
1Northwestern University Feinberg School of Medicine, Chicago, IL, United States, 2Mayo Clinic, Rochester, MN, United States, 3Siemens Medical Solutions USA, Inc., Salt Lake City, UT, United States
3D
MRE provides liver stiffness measures with less susceptibility to artifacts and
larger measurable areas of liver compared to 2D techniques. The Liver Stiffness
Measures based on 3D MRE are lower than 2D techniques.
Elastograms with overlying confidence maps
obtained with 2D GRE (A), 2D EPI (B), and 3D EPI (C) MR elastography techniques
in a 70-year-old male patient with non-alcoholic fatty liver disease. The liver
parenchyma available for LSM measurement was significantly larger with 3D MRE.
Bland-Altman
plots showing magnitude of variation of LSMs between 3D EPI and 2D GRE (A), and
between 3D EPI and 2D EPI (B). Arbitrary lines for 0.5 kPa and 1 kPa difference
in LSMs are drawn.