Two patterns of cortical thickness relate to seizure relapse in pediatric patients with epilepsy after treatment
Wenjing Zhang1, Tao Yu2, Mengyuan Xu1, Chengmin Yang1, Naici Liu1, Su Lui1, and Haibo Qu3
1Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital of Sichuan University, Chengdu, China, 2Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China, 3Department of Radiology, Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, National Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University, Chengdu, China
Using biological imaging measures and data-driven
method, we observed two different patterns of cortical morphometric features of
gray matter in the early stage of pediatric patients with epilepsy, which were associated with the seizure relapse after treatment.
Cluster dendrogram and heat
map using cortical thickness measures in pediatric patients with epilepsy.
Regional cortical thickness
differences between patient subgroups and healthy controls.