1044
Cerebral Morphometric Alterations in Patients with Temporal Lobe Epilepsy related to Antero-inferior Temporal Meningoencephalocele
Laleh Eskandarian1,2, Safak Parlak3, Gokce Ayhan4, Irsel Tezer4, Serap Saygi4, and Kader Karli Oguz2,3
1Neuroscience Department, Bilkent University, Ankara, Turkey, 2National Magnetic Resonance Research Center (UMRAM), Bilkent University, Ankara, Turkey, 3Faculty of Medicine, Department of Radiology, Hacettepe University, Ankara, Turkey, 4Faculty of Medicine, Department of Neurology, Hacettepe University, Ankara, Turkey

This study investigates morphological alterations in patients with left TLE. Compared with HCs, cortical thickness was increased extensively in both cerebral hemispheres, both amygdala were significantly bigger and no difference was found in hippocampi and thalami.

Figure 2. Cortical thickness in patients vs HC shown on the inflated surface of the brain. Red and blue show regions with significantly thicker cortex in the patients and HCs respectively.
Figure 1. Cortical areas with statistically significant increased thickness in patients compared with HCs