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T2 relaxometry and 18F-FDG-PET alterations in hippocampus and hippocampal subfields in left and right MR-negative temporal lobe epilepsy
Hui Huang1, Miao Zhang2, Wei Liu3, Jia Wang1, Lihong Tang1, Qikang Li1, Biao Li2, and Jie Luo1
1School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China, 2Department of Nuclear Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, 3Department of Neurosurgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
We demonstrated that combination of T2 and PET could complement each other in lateralization for MR-negative LTLE. Our experimental results showed different alternation of T2 relaxometry and 18F-FDG-PET in hippocampal regions.
Figure 1. The statistical comparison of hippocampal volumes, mean T2 and PET SUVR in ipsilateral hippocampus and hippocampal subregions vs contralateral regions. To the left of the line is the ipsilateral ROIs, and to the right of the line is the contralateral ROIs. MR-negative LTLE is shown in blue, and RTLE is shown in orange. The significance level in all patients is indicated by a black asterisk. * P < 0.05, ** P < 0.01, *** P < 0.001.
Figure 3. Receiver operating characteristic (ROC) curve of the classification-models.